DebraJWallaceMD

PubMed

• 1 citations
  Ring-Closing Metathesis Reactions of Bis(enynes): Selectivity and Surprises
  Debra J. Wallace, Robert A. Reamer> ;The Journal of Organic Chemistry. 2014 Jun 3
• 55 citations
  CRTH2 antagonist MK-7246: a synthetic evolution from discovery through development.
  Carmela Molinaro, Paul G. Bulger, Ernest E. Lee, Birgit Kosjek, Stephen Lau, Danny Gauvreau, Melissa E. Howard, Debra J. Wallace, Paul D. O’Shea> ;The Journal of Organic Chemistry. 2012 Feb 15
• 40 citations
  Reaction development and mechanistic study of a ruthenium catalyzed intramolecular asymmetric reductive amination en route to the dual Orexin inhibitor Suvorexant (MK-...
  Neil A. Strotman, Carl A. Baxter, Karel M. J. Brands, Ed Cleator, Shane W. Krska, Robert A. Reamer, Debra J. Wallace, Timothy J. Wright> ;Journal of the American Chemical Society. 2011 May 11
• 5 citations
  Enantioselective, biocatalytic reduction of 3-substituted cyclopentenones: application to the asymmetric synthesis of an hNK-1 receptor antagonist.
  Kevin R. Campos, Artis Klapars, Yoshinori Kohmura, David Pollard, Hideaki Ishibashi, Shinji Kato, Akihiro Takezawa, Jacob H. Waldman, Debra J. Wallace, Cheng-yi Chen, ...> ;Organic Letters. 2011 Feb 8
• 80 citations
  Phosphine-catalyzed cycloadditions of allenic ketones: new substrates for nucleophilic catalysis.
  Debra J. Wallace, Rachel L. Sidda, Robert A. Reamer> ;The Journal of Organic Chemistry. 2007 Jan 10
• 26 citations
  The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: fragment couplings, completion of the synthesis, analogue generation and biological evaluation
  Ian Paterson, David Y.-K. Chen, Mark J. Coster, Jose Luis Acena, Jordi Bach, Debra J. Wallace> ;Organic & Biomolecular Chemistry. 2005 Jun 23
• 47 citations
  Relay ring-closing metathesis-a strategy for achieving reactivity and selectivity in metathesis chemistry.
  Debra J. Wallace> ;Angewandte Chemie. 2005 Mar 18
• 26 citations
  An investigation into causes and effects of high cyanide levels in the palladium-catalyzed cyanation reaction.
  Karen Marcantonio, Lisa F. Frey, Yong Liu, Yadan Chen, Jeff Strine, Brian D. Phenix, Debra J. Wallace, Cheng-yi Chen> ;Organic Letters. 2004 Sep 16
• 71 citations
  Palladium-Catalyzed Amidation of Enol Triflates: A New Synthesis of Enamides
  Debra J. Wallace, David J. Klauber, Cheng-yi Chen, Ralph P. Volante> ;Organic Letters. 2003 Nov 7
• 54 citations
  Synthesis and antimitotic/cytotoxic activity of hemiasterlin analogues.
  James A. Nieman, John Coleman, Debra Wallace, Edward Piers, Lynette Lim, Michel Roberge, Raymond J. Andersen> ;Journal of Natural Products. 2003 Feb 1
• Stereocontrolled Total Synthesis of (+)-Altohyrtin A/Spongistatin 1 Financial support was provided by the EPSRC (GR/L41646), Cambridge Commonwealth Trust (Scholarship ...
  Paterson, I., Chen, D. Y., Coster, M. J., Aceña, J. L., Bach, J., Gibson, K. R., Keown, L. E., Oballa, R. M., Trieselmann, T., Wallace, D. J., Hodgson, A. P., Norcross...> ;Angew Chem Int Ed Engl. 2001 Nov 5
• 22 citations
  A double ring closing metathesis reaction in the rapid, enantioselective synthesis of NK-1 receptor antagonists.
  Debra J. Wallace, Jonathan M. Goodman, Derek J. Kennedy, Antony J. Davies, Cameron J. Cowden, Michael S. Ashwood, Ian F. Cottrell, Ulf H. Dolling, Paul J. Reider> ;Organic Letters. 2001 Mar 8
• The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: the CD-spiroacetal segment.
  Paterson, I., Coster, M. J., Chen, D. Y., Gibson, K. R., Wallace, D. J.> ;Org Biomol Chem. 2005 Jul 7
• The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: the AB-spiroacetal segment.
  Paterson, I., Coster, M. J., Chen, D. Y., Oballa, R. M., Wallace, D. J., Norcross, R. D.> ;Org Biomol Chem. 2005 Jul 7
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