DeepaJeyakumarMD

Oncology • Orange, CA

Hematologic Oncology

Associate Clinical Professor

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Office
Division of Hematology/Oncology UC Irvine Medical Center
101 The City Drive South Bldg 56
Orange, CA 92868
Phone+1 714-456-5153
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Education & Training

Stanford Health CareFellowship, Blood & Bone Marrow Transplant, 2012 - 2013
Tufts Medical CenterFellowship, Hematology and Medical Oncology, 2009 - 2012
University of Illinois College of Medicine at ChicagoResidency, Internal Medicine, 2005 - 2008
Lewis Katz School of Medicine at Temple UniversityClass of 2005

Certifications & Licensure

CA State Medical License 2012 - 2025
MA State Medical License 2009 - 2013
IL State Medical License 2005 - 2011
American Board of Internal Medicine Hematology
American Board of Internal Medicine Medical Oncology

Clinical Trials

Cytarabine and Daunorubicin Hydrochloride or Idarubicin and Cytarabine With or Without Vorinostat in Treating Younger Patients With Previously Untreated Acute Myeloid Leukemia Start of enrollment: 2013 Feb 12
Completed
Phase 3
Rituximab and Combination Chemotherapy With or Without Lenalidomide in Treating Patients With Newly Diagnosed Stage II-IV Diffuse Large B Cell Lymphoma Start of enrollment: 2013 Aug 27
Active, not recruiting
Phase 2
Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia Start of enrollment: 2014 May 19
Active, not recruiting
Phase 3
Ibrutinib and Rituximab Compared With Fludarabine Phosphate, Cyclophosphamide, and Rituximab in Treating Patients With Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Start of enrollment: 2014 Feb 20
Active, not recruiting
Phase 3
Ibrutinib and Azacitidine for Treatment of Higher Risk Myelodysplastic Syndrome Start of enrollment: 2016 May 17
Completed
Phase 1
CPX-351 and Glasdegib for Newly Diagnosed Acute Myelogenous Leukemia With MDS Related Changes or Therapy-related Acute Myeloid Leukemia Start of enrollment: 2020 Feb 19
Recruiting
Phase 2
CPX-351 and Gemtuzumab Ozogamicin in Treating Patients With Relapsed Acute Myeloid Leukemia Start of enrollment: 2019 Jul 18
Terminated
Phase 1
Roles: Contact, Principal Investigator
Use of Levocarnitine to Reduce Asparaginase Hepatotoxicity in Patients With Acute Lymphoblastic Leukemia Start of enrollment: 2023 Mar 03
Recruiting
Early Phase 1
Roles: Contact
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Publications & Presentations

PubMed

HyperCVAD versus pegaspargase-containing regimens for Hispanic adults with newly diagnosed B-cell acute lymphoblastic leukemia.
Benjamin J Lee, Shawn P Griffin, Jean Doh, Alexandre Chan, Stefan O Ciurea, Deepa Jeyakumar, Angela G Fleischman, Kiran Naqvi, Nicholas R Pannunzio, Susan O'Brien, Piy...> ;European Journal of Haematology. 2024 Mar 1
Strategies to Mitigate the Drug-Drug Interaction between Nirmatrelvir/Ritonavir and Tacrolimus in Allogeneic Hematopoietic Stem Cell Transplant Recipients on Azole Ant...
Griffin, S., Lee, B., Doh, J., Paradyse, A., Jeyakumar, D., Arter, Z., Nam, H., Blodget, E., Smith, J., Valek, A., Vittayawacharin, P., Kongtim, P., Ciurea, S.> ;Acta Haematologica. 2023 Oct 9
Measurable residual disease conversion rate with consolidation chemotherapy in acute myeloid leukemia.
Daria Gaut, Caspian Oliai, Jonathan Boiarsky, Shiliang Zhang, Amandeep Salhotra, Tali Azenkot, Vanessa E Kennedy, Vishesh Khanna, Karla Olmedo Gutierrez, Navika Shukla...> ;Leukemia & Lymphoma. 2024 Jan 1
3 citations
Tolerability and Efficacy of the Anticluster of Differentiation 47 Antibody Magrolimab Combined With Azacitidine in Patients With Previously Untreated AML: Phase Ib Re...
Naval G Daver, Paresh Vyas, Suman Kambhampati, Monzr M Al Malki, Richard A Larson, Adam S Asch, Gabriel Mannis, Wanxing Chai-Ho, Tiffany N Tanaka, Terrence J Bradley, ...> ;Journal of Clinical Oncology. 2023 Nov 1
4 citations
Glasdegib plus intensive or non-intensive chemotherapy for untreated acute myeloid leukemia: results from the randomized, phase 3 BRIGHT AML 1019 trial.
Mikkael A Sekeres, Pau Montesinos, Jan Novak, Jianxiang Wang, Deepa Jeyakumar, Benjamin Tomlinson, Jiri Mayer, Erin Jou, Tadeusz Robak, David C Taussig, Hervé Dombret,...> ;Leukemia. 2023 Oct 1
2 citations
Impact of prior therapies and subsequent transplantation on outcomes in adult patients with relapsed or refractory B-cell acute lymphoblastic leukemia treated with bre...
Bijal D Shah, Ryan D Cassaday, Jae H Park, Roch Houot, Olalekan O Oluwole, Aaron C Logan, Nicolas Boissel, Thibaut Leguay, Michael R Bishop, Max S Topp, Dimitrios Tzac...> ;Journal for Immunotherapy of Cancer. 2023 Aug 1
3 citations
A phase 1b study of venetoclax and alvocidib in patients with relapsed/refractory acute myeloid leukemia.
Brian A Jonas, Jing-Zhou Hou, Gail J Roboz, Caroline L Alvares, Deepa Jeyakumar, John R Edwards, Harry P Erba, Richard J Kelly, Christoph Röllig, Walter Fiedler, Deann...> ;Hematological Oncology. 2023 Oct 1
Impact of triple intrathecal prophylaxis in acute lymphoblastic leukemia adults receiving HyperCVAD: A COVID-19 practice change.
Benjamin J Lee, Piyanuch Kongtim, Jean Doh, Shawn P Griffin, Alexandre Chan, Susan O'Brien, Stefan O Ciurea, Deepa Jeyakumar> ;European Journal of Haematology. 2023 Jul 1
3 citations
Once-Daily Foscarnet Is Effective for Human Herpesvirus 6 Reactivation after Hematopoietic Stem Cell Transplantation.
Pongthep Vittayawacharin, Ghayda' E'Leimat, Benjamin J Lee, Shawn Griffin, Jean Doh, Hannah Nam, Emily Blodget, Deepa Jeyakumar, Piyanuch Kongtim, Stefan O Ciurea> ;Transplantation and Cellular Therapy. 2023 Jun 1
Timing of intrathecal chemotherapy and blinatumomab impacts neurotoxicity in acute lymphoblastic leukemia.
Benjamin J Lee, Shawn P Griffin, Jean Doh, Piyanuch Kongtim, Alexandre Chan, Susan O'Brien, Deepa Jeyakumar, Stefan O Ciurea> ;American Journal of Hematology. 2023 May 1
18 citations
Two-year follow-up of KTE-X19 in patients with relapsed or refractory adult B-cell acute lymphoblastic leukemia in ZUMA-3 and its contextualization with SCHOLAR-3, an ...
Bijal D Shah, Armin Ghobadi, Olalekan O Oluwole, Aaron C Logan, Nicolas Boissel, Ryan D Cassaday, Thibaut Leguay, Michael R Bishop, Max S Topp, Dimitrios Tzachanis, Kr...> ;Journal of Hematology & Oncology. 2022 Dec 10
10 citations
Dasatinib/prednisone induction followed by blinatumomab/dasatinib in Ph+ acute lymphoblastic leukemia.
Anjali S Advani, Anna Moseley, Kristen M O'Dwyer, Brent L Wood, Jae Park, Matthew Wieduwilt, Deepa Jeyakumar, George Yaghmour, Ehab L Atallah, Aaron T Gerds, Susan M O...> ;Blood Advances. 2023 Apr 11
3 citations
CD19-directed immunotherapy use in KMT2A-rearranged acute leukemia: A case report and literature review of increased lymphoid to myeloid lineage switch.
Benjamin J Lee, Shawn P Griffin, Jean Doh, Alexandre Chan, Susan O'Brien, Deepa Jeyakumar, Stefan O Ciurea, Pamela S Becker, Piyanuch Kongtim> ;American Journal of Hematology. 2022 Dec 1
2 citations
Increased incidence of Pegaspargase-induced hypertriglyceridemia and associated pancreatitis observed in the Hispanic adult patient population.
Benjamin J Lee, Jean Doh, Alexandre Chan, Deepa Jeyakumar, Susan O'Brien> ;Leukemia & Lymphoma. 2022 Dec 1
254 citations
KTE-X19 for relapsed or refractory adult B-cell acute lymphoblastic leukaemia: phase 2 results of the single-arm, open-label, multicentre ZUMA-3 study
Bijal D. Shah, Armin Ghobadi, Olalekan O. Oluwole, Aaron C Logan, Nicolas Boissel, Ryan D. Cassaday, Thibaut Leguay, Michael R. Bishop, Max S. Topp, Dimitrios Tzachani...> ;Lancet. 2021 Aug 7
6 citations
Minimal Residual Disease in Acute Myeloid Leukemia.
Deepa Jeyakumar, Susan O'Brien> ;JAMA Oncology. 2020 Dec 1
1 citations
Prolymphocytic transformation of lymphoplasmacytic lymphoma: an extremely unusual event
Kuixing Zhang, Daniel Farrell, Deepa Jeyakumar, Susan O'Brien, Xiaohui Zhao, Sherif Rezk> ;Human Pathology. 2019 Aug 1
6 citations
The Next Generation of Targeted Molecules for the Treatment of Chronic Lymphocytic Leukemia
Deepa Jeyakumar, Susan O'Brien> ;Oncology. 2016 Nov 15
3 citations
A Patient with Supraclavicular Lymphadenopathy and Anterior Mediastinal Mass Presenting as a Rare Case of Composite Lymphoma: A Case Report and Literature Review.
Alex Raufi, James H. Jerkins, Yung Lyou, Deepa Jeyakumar> ;Case Reports in Oncology. 2016 Sep 1
7 citations
B cell receptor inhibition as a target for CLL therapy
Deepa Jeyakumar, Susan O'Brien> ;Best Practice & Research. Clinical Haematology. 2016 Mar 1
1 citations
An ab initio molecular orbital study of the reduction of carbonyls by alkylaluminum complexes
Jeanne Wilson Bundens, Pamela R. Seida, Deepa Jeyakumar, Michelle Francl> ;Journal of Molecular Graphics & Modelling. 2005 Dec 1
46 citations
Long HIV type 1 reverse transcripts can accumulate stably within resting CD4+ T cells while short ones are degraded.
William J. Swiggard, Una O'Doherty, David McGain, Deepa Jeyakumar, Michael H. Malim> ;AIDS Research and Human Retroviruses. 2004 Jul 5
190 citations
A Sensitive, Quantitative Assay for Human Immunodeficiency Virus Type 1 Integration
Una O'Doherty, William J. Swiggard, Deepa Jeyakumar, David McGain, Michael H. Malim> ;Journal of Virology. 2002 Nov 1
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Journal Articles

Prolymphocytic Transformation of Lymphoplasmacytic Lymphoma; An Extremely Unusual Event
Kuixing Zhang, Daniel Farrell, Deepa Jeyakumar, Sherif A Rezk, ScienceDirect

Abstracts/Posters

Blinatumomab in Combination with Pembrolizumab Is Safe for Adults with Relapsed or Refractory B-Lineage Acute Lymphoblastic Leukemia: University of California Hematolo...
Deepa Jeyakumar, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019