DennisEHallahanMDFASTRO

PubMed

• 1 citations
  Blocking the functional domain of TIP1 by antibodies sensitizes cancer to radiation therapy.
  Abhay K Singh, David Ya Dadey, Michael J Rau, James Fitzpatrick, Harendra K Shah, Minakshi Saikia, Reid Townsend, Dinesh Thotala, Dennis E Hallahan, Vaishali Kapoor> ;Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 2023 Oct 1
• 23 citations
  Long-Acting Recombinant Human Interleukin-7, NT-I7, Increases Cytotoxic CD8 T Cells and Enhances Survival in Mouse Glioma Models.
  Jian L Campian, Subhajit Ghosh, Vaishali Kapoor, Ran Yan, Sukrutha Thotala, Arijita Jash, Tong Hu, Anita Mahadevan, Kasem Rifai, Logan Page, Byung Ha Lee, Sara Ferrand...> ;Clinical Cancer Research. 2022 Mar 15
• 2 citations
  Exploiting Radiation Induction of Antigens in Cancer: Targeted Drug Delivery.
  Vaishali Kapoor, Abhay K Singh, Calvin D Lewis, Sapna Deore, Dennis E Hallahan> ;International Journal of Molecular Sciences. 2022 Mar 11
• In Regard to Salama et al
  Stephanie M. Perkins, Dennis E. Hallahan, Julie K. Schwarz> ;International Journal of Radiation Oncology, Biology, Physics. 2021 Jul 1
• 8 citations
  Targeting a Radiosensitizing Antibody-Drug Conjugate to a Radiation-Inducible Antigen
  Calvin D. Lewis, Abhay Kumar Singh, Fong Fu Hsu, Dinesh Thotala, Dennis E. Hallahan, Vaishali Kapoor> ;Clinical Cancer Research. 2021 Jun 1
• 4 citations
  Targetability of cervical cancer by magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU)-mediated hyperthermia (HT) for patients receiving radiation t...
  Lifei Zhu, Yi Huang, Dao Lam, H. Michael Gach, Imran Zoberi, Dennis E. Hallahan, Perry W. Grigsby, Hong Chen, Michael B. Altman> ;International Journal of Hyperthermia. 2021 Jan 1
• 41 citations
  Tumor microenvironment-targeted nanoparticles loaded with bortezomib and ROCK inhibitor improve efficacy in multiple myeloma.
  Cinzia Federico, Kinan Alhallak, Jennifer Sun, Kathleen Duncan, Feda Azab, Gail Sudlow, Pilar de la Puente, Barbara Muz, Vaishali Kapoor, Luna Zhang, Fangzheng Yuan, M...> ;Nature Communications. 2020 Nov 27
• 10 citations
  TAF15 contributes to the radiation-inducible stress response in cancer
  Abhay Kumar Singh, Vaishali Kapoor, Dinesh Thotala, Dennis E. Hallahan> ;Oncotarget. 2020 Jul 7
• 2 citations
  Concurrent chemo-radiotherapy with proton therapy: reduced toxicity with comparable oncological outcomes vs photon chemo-radiotherapy
  Brian C. Baumann, Dennis E. Hallahan, Jeff M. Michalski, James M. Metz, Carlos A. Perez> ;British Journal of Cancer. 2020 Jun 18
• 6 citations
  Radiation induces iatrogenic immunosuppression by indirectly affecting hematopoiesis in bone marrow.
  Vaishali Kapoor, Andrea Collins, Kaylan Griffith, Subhajit Ghosh, Nathan Wong, Xiaowei Wang, Grant A. Challen, Joseph R. Krambs, Daniel C. Link, Dennis E. Hallahan, Di...> ;Oncotarget. 2020 May 12
• 2 citations
  Characterization of magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU)-induced large-volume hyperthermia in deep and superficial targets in a porcin...
  Lifei Zhu, Dao Lam, Christopher Pham Pacia, H. Michael Gach, Ari Partanen, Michael Talcott, Suellen Greco, Imran Zoberi, Dennis E. Hallahan, Hong Chen, Michael B. Altman> ;International Journal of Hyperthermia. 2020 Jan 1
• 9 citations
  Feasibility and safety assessment of magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU)-mediated mild hyperthermia in pelvic targets evaluated using...
  Lifei Zhu, Ari Partanen, Michael Talcott, H. Michael Gach, Suellen Greco, Lauren E. Henke, Jessika Contreras, Imran Zoberi, Dennis E. Hallahan, Hong Chen, Michael B. A...> ;International Journal of Hyperthermia. 2019 Nov 21
• 37 citations
  Association of Posttreatment Lymphopenia and Elevated Neutrophil-to-Lymphocyte Ratio With Poor Clinical Outcomes in Patients With Human Papillomavirus-Negative Orophar...
  Alexander J. Lin, Y.J. Rao, Jian Campian, Mackenzie Daly, Peter Oppelt, Ryan S. Jackson, Jason T. Rich, Randal C. Paniello, Jose P. Zevallos, Dennis E. Hallahan, Dougl...> ;JAMA Otolaryngology-- Head & Neck Surgery. 2019 May 1
• 53 citations
  Ultrasound Hyperthermia Technology for Radiosensitization.
  Lifei Zhu, Michael B. Altman, Andrei Laszlo, William L. Straube, Imran Zoberi, Dennis E. Hallahan, Hong Chen> ;Ultrasound in Medicine & Biology. 2019 May 1
• 9 citations
  PEGylated peptide to TIP1 is a novel targeting agent that binds specifically to various cancers in vivo.
  Vaishali Kapoor, Abhay Kumar Singh, Buck E. Rogers, Dinesh Thotala, Dennis E. Hallahan> ;Journal of Controlled Release. 2019 Mar 28
• 3 citations
  ATM Inhibition Sensitizes Tumors to High-Dose Irradiation.
  Dennis E. Hallahan> ;Cancer Research. 2019 Feb 15
• 241 citations
  Phase I/II Trial of Electrophysiology-Guided Noninvasive Cardiac Radioablation for Ventricular Tachycardia.
  Clifford G. Robinson, Pamela Samson, K.M.S. Moore, Geoffrey D. Hugo, Nels C. Knutson, Sasa Mutic, S. Murty Goddu, Adam Lang, Daniel H. Cooper, Mitchell N. Faddis, Amit...> ;Circulation. 2019 Jan 15
• 16 citations
  Molecular and epigenetic regulatory mechanisms of normal stem cell radiosensitivity.
  Maria Rita Fabbrizi, Kacie E. Warshowsky, Cheri L. Zobel, Dennis E. Hallahan, Girdhar G. Sharma> ;Cell Death Discovery. 2018 Dec 18
• Retraction Note: Reprogramming glioblastoma multiforme cells into neurons by protein kinase inhibitors.
  Jie Yuan, Fan Zhang, Dennis E. Hallahan, Zhen Zhang, Liming He, Ling-Gang Wu, Meng You, Qin Yang> ;Journal of Experimental & Clinical Cancer Research. 2018 Dec 1
• 29 citations
  Post-operative radiation effects on lymphopenia, neutrophil to lymphocyte ratio, and clinical outcomes in palatine tonsil cancers.
  Alexander J. Lin, Yuan James Rao, R.I. Chin, Jian Campian, D. Mullen, Dinesh Thotala, Mackenzie Daly, Peter Oppelt, Dennis E. Hallahan, Douglas Adkins, Wade L. Thorstad> ;Oral Oncology. 2018 Sep 7
• 29 citations
  PERK Regulates Glioblastoma Sensitivity to ER Stress Although Promoting Radiation Resistance.
  David Y. A. Dadey, Vaishali Kapoor, Arpine Khudanyan, Dinesh Thotala, Dennis E. Hallahan> ;Molecular Cancer Research. 2018 Oct 1
• 9 citations
  Reprogramming glioblastoma multiforme cells into neurons by protein kinase inhibitors.
  Jie Yuan, Fan Zhang, Dennis E. Hallahan, Zhen Zhang, Liming He, Ling-Gang Wu, Meng You, Qin Yang> ;Journal of Experimental & Clinical Cancer Research. 2018 Aug 2
• 10 citations
  A convenient, reliable, and fast acoustic pressure field measurement method for magnetic resonance-guided high-intensity focused ultrasound systems with phased array t...
  Satya V.V.N. Kothapalli, Ari Partanen, Lifei Zhu, Michael B. Altman, H. Michael Gach, Dennis E. Hallahan, Hong Chen> ;Journal of Therapeutic Ultrasound. 2018 Jul 2
• 10 citations
  Transient PP2A inhibition alleviates normal tissue stem cell susceptibility to cell death during radiotherapy.
  Maria Rita Fabbrizi, Barbara Meyer, Sandeep Misri, Suyash Raj, Cheri L. Zobel, Dennis E. Hallahan, Girdhar G. Sharma> ;Cell Death & Disease. 2018 May 1
• 16 citations
  Association of 1p/19q Codeletion and Radiation Necrosis in Adult Cranial Gliomas After Proton or Photon Therapy
  Sahaja Acharya, Clifford G. Robinson, Jeff M. Michalski, D. Mullen, Todd DeWees, Jian Campian, Anupama Chundury, Beth Bottani, Dennis E. Hallahan, Jeffrey Bradley, Jia...> ;International Journal of Radiation Oncology, Biology, Physics. 2018 Jun 1
• Join now to see all

Journal Articles

• Radiation induced signal transduction through cPLA2 and Autotaxin.  
  Laszlo A, Thotala D, Hallahan DE, Lipid signaling, 1/1/2013
• Membrane Phospholipids, EML4-ALK and Hsp90, as Novel Targets in Lung Cancer Treatment.  
  Laszlo A, Thotala D, Hallahan DE, The Cancer Journal, 1/1/2013
• High-throughput identification of putative receptors for cancer-binding peptides using biopanning and microarray analysis.  
  Ferraro DJ, Bhave S, Kotipatruni R, Hunn J, Wildman S, Hong C, Jaboin J, Thotala D, Hallahan DE, Integrative Biology, 1/1/2013
• Cytosolic PhospholipaseA2 Inhibition with Giripladib Radiosensitizes Tumors in Lung Cancer Animal Models.  
  Thotala DK, Craft JM, Leahy K, Hung R, Hallahan DE, PLOS One, 1/1/2013
• Autotaxin and Lysophosphatidic Acid Receptors as Novel Targets for the radiosensitization of Tumor Vasculature in Non-Small Cell Lung Cancer.  
  Linkous AG, Hallahan DE, Yazlovitskaya EM, Current Angiogenesis, 1/1/2012
•  
  Thotala D, Hallahan DE, Yazlovetzkaya E, Cell Death and Differentiation, 1/1/2012
• NDRG4, the N-Myc downstream regulated gene, is important for cell survival, tumor invasion and angiogenesis in meningiomas.  
  Kotipatruni RP, Ferraro DJ, Ren X, Vanderwaal RP, Thotala DK, Hallahan DE, Jaboin JJ, Integrative Biology, 1/1/2012
• Kinomic profiling approach identifies Trk as a novel radiation modulator.  
  Jarboe JS, Jabon JJ, Anderson JC, Nowsheen S, Stanley J, Ruijtenbeek R, Tu T, Hallahan DE, Yang ES, Bonner JA, Willey CD, International Journal of Radiation Biology, 1/1/2012
• Towards novel radiosensitizing agents: cPLA2 inhibitors in combined modality cancer therapy.  
  Craft J, Hallahan DE, Future Medicinal Chemistry, 1/1/2011
• GSK-3 inhibition promotes cell death, apoptosis, and in vivo tumor growth delay in neuroblastoma Neuro-2A cell line.  
  Dickey A, Schleicher S, Thotala D, Hallahan DE, Journal of Neuro-Oncology, 1/1/2011
• Autotaxin and LPA receptors represent potential molecular targets for the radiosensitization of malignant glioma through effects on tumor vasculature.  
  Schleicher S, Thotala D, Hallahan DE, PLoS ONE, 1/1/2011
• Tumor-targeted delivery of liposome-encapsulated doxorubicin by use of a peptide that selectively binds to irradiated tumors.  
  Lowery AR, Onishko HM, Hallahan D, Han Z, Journal of Controlled Release, 1/1/2011
• Tumor-targeted delivery of liposome-encapsulated doxorubicin by use of a peptide that selectively binds to irradiated tumors  
  Hariri G, Wellons MS, Morris WH III, Lukehart CM, Hallahan DE, Journal of Controlled Release, 1/1/2011
• Multifunctional FePt Nanoparticles for Radiation-Guided Targeting and Imaging of Cancer.  
  Schulte RR, Linkous AG, Hallahan DE, Yazlovitskaya EM, Annals of Biomedical Engineering,, 1/1/2011
• Cytosolic phospholipase A2 as a novel molecular target for the radiosensitization of ovarian cancer  
  Craft JM, Hallahan D, Cancer Letters, 1/1/2011
•  
  Thotala D, Hallahan DE, Yazlovetzkaya E, Int J Radiat Oncol Biol Physics, 2/1/2010
• Cytosolic Phospholipase A2: and phospholipids in tumor angiogenesis.  
  Linkous A, Yazlovetzkaya E, Hallahan DE, J. Natl Cancer Inst., 1/1/2010
• Targeted nanoparticles that deliver a sustained, specific release of Paclitaxel to irradiated tumors.  
  Passarella RJ, Spratt DE, van der Ende AE, Phillips JG, Wu H, Sathiyakumar V, Zhou L, Hallahan DE, Harth E, Diaz R, Cancer Research, 1/1/2010
• Radiation guided nanoparticle drug delivery to cancer.  
  Hariri G, Yan H, Wang H, Han Z, Hallahan DE, Clinical Cancer Research, 1/1/2010
• Correlation of Quantified Contrast-Enhanced Sonography to In Vivo Tumor Response.  
  Hwang M, Lyshchik A, Hariri G, Hallahan DE, Fleischer AC, J Ultrasound Medicine, 1/1/2010
• Linear Therapies Release Nanoparticle Devices for Advanced Targeted Cancer with Increased Efficacy.  
  van der Ende AE, Sathiyakumar S, Diaz R, Hallahan DE, Harth E, Polymer Chemistry, 1/1/2010
• Ionizing Radiation for Tumor-Targeted Drug Delivery.  
  Diaz R, Zhou L, Hallahan DE, Targeted Delivery of Small and Macromolecular Drugs, 1/1/2010
• TIP-1 Translocation onto the Cell Plasma Membrane Is a Molecular Biomarker of Tumor Response to Ionizing Radiation.  
  Wang H, Hallahan DE, Han X, PLOS One, 1/1/2010
• Pyridoxamine protects intestinal epithelium from ionizing radiation-induced apoptos.  
  Thotala D, Chetyrkin S, Hudson B, Hallahan D, Voziyan P, Yazlovitskaya E, Free Redicals in Biology, 9/1/2009
• Merkel cell carcinoma.  
  Miller SJ, Alam M, Andersen J, Berg D, Bichakjian CK, Bowen G, Cheney RT, Glass LF, Grekin RC, Hallahan DE, et al, J Natl Compr Canc Netw, 3/1/2009
• Join now to see all

Books/Book Chapters

• Targeted Delivery of Small and Macromolecular Drugs. 
  Chapter: The use of ionizing radiation for tumor targeted drug delivery. 
  Diaz R, Zhou L, Hallahan DEEditors: Narang A, Mahato R.CRC Press2009
• Abeloff’s Clinical Oncology. 
  Chapter: Cancer of the lung. 
  Johnson, DH., Blot, W., Carbone, D., Gonzalez, A., Hallahan, D., Massion, P., Putnam, JB., Sandler, AEditors: Abeloff, Armitage, Niederhuber, Kastan, McKenna.Churchill Livingstone2008
• Inflammation and Cell Adhesion Molecules are Involved in Radiation-Induced Lung Injury. 
  Willey CD, Hallahan DEEditors: Rubin.Springer, Germany2007
• Lung Cancer: Principles and Practice. 
  Chapter: Cell Cycle and Vascular Targets for Radiotherapy. 
  Moretti L, Ocak S, Hwang M, Lu B, Hallahan DEEditors: Johnson D.2007
• Multimodal Concepts for Integration of Cytotoxic Drugs and Radiation Therapy. 
  Chapter: Radiotherapy and tumor-targeted drug delivery. 
  Page 151 - 162Han ZZ, Hariri G, Hallahan DEEditors: Brown JM, Mehta MP, Nieder C.Springer Press2006
• Advances in Radiation Oncology 
  Chapter: The role of gene therapy in radiation oncology. 
  Page 153 - 168Hallahan, DE, Weichselbaum, RREditors: Mittal, Purdy, Ang.Kluwer Academic Publishers, Boston, MA1999
• Ionizing Radiation: A molecular switch for gene therapy. 
  Weichselbaum,RR, Wayne, JD, Mauceri, HJ, Seung, LP, Hanna, NN, Kharbanda, S, Kufe, DW, Hallahan, DEPrentice Hall Health1995
• Internet Book of Gene Therapy 
  Chapter: Ionizing Radiation: A molecular switch for gene therapy. 
  Weichselbaum RR, Wayne JD, Mauceri HJ, Seung LP, Hanna NN, Kharbanda S, Kufe DW, Hallahan DE1995
• Cancer Medicine 
  Chapter: Physical and biological basis to radiation oncology. 
  Weichselbaum RR, Hallahan DE, Chen GTYEditors: Holland J, Frei E, Bast RC, Kufe D, Morton DL, Weichselbaum RR.Lea and Febiger, Malvern, PAEdition 3rd,1993
• Important advances in Oncology. 
  Chapter: Role of Cytokines in Radiation Oncology. 
  Hallahan DE, Haimovitz-Friedman A, Kufe DW, Fuks Z, Weichselbaum RREditors: DeVita, Hellman, Rosenberg.Lippincott, PA1993
• Mechanisms of Drug Resistance. 
  Chapter: Signal transduction and gene expression during mammalian cell response to ionizing radiation. 
  Page 603 - 614Hallahan DE, Kufe D, Weichselbaum RREditors: Teicher B.Marcel Dekker, New York, NY1992
• Neoplastic transformation in human cell systems in vitro: Mechanisms of Carcinogenesis. 
  Chapter: Ionizing radiation-mediated protein kinase C activation and gene expression. 
  Page 81 - 92Hallahan DE, Sherman M, Kufe D, Weichselbaum RREditors: Rheim J, Dritschilo A.Humana Press Inc., Clifton, NJ1991
• Radiation Research: a Twentieth Century Perspective. 
  Chapter: Gene induction by ionizing radiation. 
  Page 375 - 379Weicheslbaum RR, Hallahan DE, Kufe DWEditors: Chapman JD, Dewey WC, Whitmore GF.Academic Press, San Diego, CA1991
• Join now to see all

Lectures

• Highlights; Radiation guided delivery of nanoparticles. 
  NCI Workshop on image guided therapy. - 1/1/2013
• Mission and Vision of Washington Unviersity Dept of Radiation Oncology 
  Varian Medical Systems Retreat. - 1/1/2013
• Nanoparticles and drug delivery. 
  European Society for Radiation Oncology. - 1/1/2013
• Radiation guided drug delivery 
  University of Missouri, Nuclear Engineering, 2010; Varian Medical Systems, 2012; - 1/1/2012
• Molecular Imaging 
  Stanford. - 1/1/2012
• Physician Scientist in Radiation Oncology 
  Society for Chairmen of Radiation Oncology Programs (SCAROP). - 1/1/2012
• Radiation-inducible neoantigens 
  Oregon Health Sciences U. - 1/1/2012
• Radiation guided nanoparticles and antibodies. 
  Emory. - 1/1/2011
• Symposium on nanotechnology. 
  ASTRO, Miami, FL. - 1/1/2011
• Symposium on Normal Tissue Injury. 
  Am. Assoc. Physicists Medicine, Vancouver, Canada. - 1/1/2011
• Translation research symposium. 
  ASTRO, Atlanta, GA. - 1/1/2011
• PLA2 inhibitors for cancer therapy. 
  St Louis Pharmacology Club. - 1/1/2010
• Nanoparticle Characterization Lab. 
  NCI, Fredericksburg. - 1/1/2010
• Radiation Oncology. 
  Gordon Conference, Keynote Speaker. - 1/1/2010
• Conformal Drug delivery. 
  Presidential Symposium, ASTRO Annual Meeting. - 1/1/2009
• Pediatric Radiation Oncology Society. 
  Montreal. - 1/1/2009
• Mentoring the Mentor. 
  ASTRO Symposium, Boston, MA. - 9/1/2008
• New Paradigms in Radiation Oncology 
  University of Pennsylvania; Eli Gladstein Translational Research Conference. - 1/1/2008
• Imaging Cancer Response . 
  Bracco Research USA, Princeton NJ, 2008; Bracco Inc, Geneva, Switzerland, 2008. - 1/1/2008
• Molecular Targets for Radiation Protection. 
  Radiation Research Society Symposium. Amercan Society for Radiology Oncology /Radiation Research Soc - 1/1/2008
• Imaging Pharmacodynamics of cancer response. 
  Johns Hopkins Cancer Center, Grand Rounds, 2006; Oncology grand rounds, Georgetown Cancer Center, 20 - 1/1/2008
• Guiding drug delivery by use of ionizing radiation. 
  National Cancer Institute. - 1/1/2007
• Mechanisms of radiation-induced tumor immune response. 
  NCI Workshop. - 1/1/2007
• Radiotherapy for lung cancer. 
  Hoffman-LaRoche Preceptorship. - 1/1/2007
• Sutent and Radiation Therapy. 
  Pfizer, New York, NY. - 1/1/2007
• Join now to see all

Other

•  
  Jacobs KM, Bhave SR, Ferraro DJ, Jaboin JJ, Hallahan DE, Thotala D
  1/1/2012
• Microarray Informatic Array design name: VMSR M. musculus MEEBO 38.5K v1.0 
  Yazlovetzkaya E, Fu A, Hallahan DE
  http://www.ebi.ac.uk/arrayexpress/Submissions/
  European Bioinformatic Institute - 1/1/2005
• Symposium Chair 
  Hallahan D
  Radiation Research. - 1/1/2000
• Sugen, Inc. Visiting Professor 
  Hallahan D
  CA. - 1/1/2000
• ICOS, Inc., Visiting Professor 
  Hallahan D
  Seattle, WA. - 1/1/1999
• Moderator. 
  Hallahan D
  American Society of Therapeutic Radiology and Oncology. - 1/1/1994
• Differential radiation responses and radio- sensitivity of stem cells. 
  Sharma G, Thotala D, Hallahan DE
• Join now to see all