DennisMichaelMarcusMD

Ophthalmology • Augusta, GA

Retinal Disease

Physician

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Office
3685 Wheeler Rd
Suite 201
Augusta, GA 30909
Phone+1 706-650-0061

Fax+1 706-650-0064
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Education & Training

Massachusetts Eye and Ear Infirmary/Harvard Medical SchoolResidency, Ophthalmology, 1990 - 1993
Hackensack University Medical Center (Palisades)Internship, Transitional Year, 1987 - 1988
Albert Einstein College of MedicineClass of 1987

Certifications & Licensure

FL State Medical License 2023 - 2026
MA State Medical License 2023 - 2026
IL State Medical License 2023 - 2026
SC State Medical License 1997 - 2025
GA State Medical License 1994 - 2025
NY State Medical License 2023 - 2025
American Board of Ophthalmology Ophthalmology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification MaximEyes SQL EHR, First Insight Corporation, 2012
Fellow (FAAO) American Academy of Ophthalmology

Clinical Trials

Intravitreal Ranibizumab for Vitreous Hemorrhage Due to Proliferative Diabetic Retinopathy (N) Start of enrollment: 2010 Jun 01
Completed
Phase 2, Phase 3
NSAID Phase II for Non-central Involved Diabetic Macular Edema (DME) Start of enrollment: 2011 May 01
Completed
Phase 2
Safety Study of 2.0mg Lucentis to Treat Polypoidal Choroidal Vasculopathy Start of enrollment: 2011 Sep 01
Completed
Phase 1, Phase 2
A Randomized, Multi-center, Phase II Study of the Safety, Tolerability and Bioactivity of Repeated Intravitreal Injections of iCo-007 as Monotherapy or in Combination With Ranibizumab or Laser Photocoagulation in the Treatment of Diabetic Macular Edema (the iDEAL Study) Start of enrollment: 2012 Feb 01
Terminated
Phase 2
Treatment for Presumed Ocular Histoplasmosis Start of enrollment: 2013 Mar 01
Unknown status
Phase 1, Phase 2
Ranibizumab For Persistent Diabetic Macular Edema After Bevacizumab Start of enrollment: 2013 Apr 01
Unknown status
Phase 1, Phase 2
Ocriplasmin Research to Better Inform Treatment (ORBIT) Start of enrollment: 2014 May 01
Completed
Intravitreal Aflibercept for Neovascular Polypoidal Choroidal Vasculopathy (RIVAL Trial) Start of enrollment: 2014 Mar 01
Unknown status
Phase 4
IAI for Persistent DME After Treatment With Bevacizumab And Ranibizumab Start of enrollment: 2015 Jun 01
Completed
Phase 4
A Study to Test How Well Different Doses of BI 754132 Are Tolerated in Patients With an Advanced Form of Age-related Macular Degeneration Called Geographic Atrophy Start of enrollment: 2019 Jul 26
Terminated
Phase 1
Evaluation of Additional Heidelberg Engineering SPECTRALIS With OCT Angiography Module (OCTA Module) Scan Types Start of enrollment: 2020 Oct 15
Completed
Endolaserless Vitrectomy With Intravitreal IAI for PDR-Related VH Start of enrollment: 2016 Jun 01
Unknown status
Phase 1, Phase 2
Roles: Contact, Principal Investigator
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Publications & Presentations

PubMed

Reply to Letter to the Editor: Endolaserless Vitrectomy With Aflibercept Monotherapy for Proliferative Diabetic Retinopathy-Related Vitreous Hemorrhage.
Venkatkrish M Kasetty, Dennis M Marcus> ;Ophthalmic Surgery, Lasers & Imaging Retina. 2023 Oct 1
21 citations
Aflibercept Monotherapy or Bevacizumab First for Diabetic Macular Edema.
Chirag D Jhaveri, Adam R Glassman, Frederick L Ferris 3rd, Danni Liu, Maureen G Maguire, John B Allen, Carl W Baker, David Browning, Matthew A Cunningham, Scott M Frie...> ;The New England Journal of Medicine. 2022 Aug 25
18 citations
Association of Ultra-Widefield Fluorescein Angiography-Identified Retinal Nonperfusion and the Risk of Diabetic Retinopathy Worsening Over Time.
Paolo S Silva, Dennis M Marcus, Danni Liu, Lloyd Paul Aiello, Andrew Antoszyk, Michael Elman, Scott Friedman, Adam R Glassman, Joseph M Googe, Lee Merrill Jampol, Dani...> ;JAMA Ophthalmology. 2022 Oct 1
21 citations
Association of Predominantly Peripheral Lesions on Ultra-Widefield Imaging and the Risk of Diabetic Retinopathy Worsening Over Time.
Dennis M Marcus, Paolo S Silva, Danni Liu, Lloyd Paul Aiello, Andrew Antoszyk, Michael Elman, Scott Friedman, Adam R Glassman, Joseph M Googe, Lee Merrill Jampol, Dani...> ;JAMA Ophthalmology. 2022 Oct 1
6 citations
A Phase I, Single Ascending Dose Study of GEM103 (Recombinant Human Complement Factor H) in Patients with Geographic Atrophy.
Arshad M Khanani, Raj K Maturi, Nika Bagheri, Benjamin Bakall, David S Boyer, Stephen S Couvillion, Dilsher S Dhoot, Nancy M Holekamp, Karim N Jamal, Dennis M Marcus, ...> ;Ophthalmology Science. 2022 Jun 1
2 citations
Optical coherence tomography angiography and Humphrey visual field in patients with obstructive sleep apnea.
Arash Davanian, Lindsay Williamson, Caitlen Taylor, Abigail Harrover, Kathryn Bollinger, Bashir Chaudhary, Varsha Taskar, Tae Jin Lee, Yuhan Liu, Qingxia Chen, Dennis ...> ;Journal of Clinical Sleep Medicine. 2022 Sep 1
11 citations
A Randomized Trial of Photobiomodulation Therapy for Center-Involved Diabetic Macular Edema with Good Visual Acuity (Protocol AE).
Judy E. Kim, Adam R. Glassman, Kristin Josic, Michele Melia, Lloyd Paul Aiello, Carl W. Baker, Janis T. Eells, Lee M. Jampol, Timothy S. Kern, Dennis M. Marcus, Daniel...> ;Ophthalmology. Retina. 2021 Oct 7
63 citations
Effect of Intravitreous Anti-Vascular Endothelial Growth Factor vs Sham Treatment for Prevention of Vision-Threatening Complications of Diabetic Retinopathy: The Proto...
Raj K. Maturi, Adam R. Glassman, Kristin Josic, Andrew N. Antoszyk, Barbara A Blodi, Lee M. Jampol, Dennis M. Marcus, Daniel F. Martin, Michele Melia, Hani Salehi-Had,...> ;JAMA Ophthalmology. 2021 Jul 1
20 citations
Suprachoroidal CLS-TA plus Intravitreal Aflibercept for Diabetic Macular Edema: A Randomized, Double-Masked, Parallel-Design, Controlled Study.
Mark R. Barakat, Charles C. Wykoff, Victor H. Gonzalez, Allen Hu, Dennis M. Marcus, Eric Zavaleta, Thomas A. Ciulla> ;Ophthalmology. Retina. 2021 Jan 1
166 citations
The Port Delivery System with Ranibizumab for Neovascular Age-Related Macular Degeneration: Results from the Randomized Phase 2 Ladder Clinical Trial
Peter A. Campochiaro, Dennis M. Marcus, Carl C. Awh, Carl D. Regillo, Anthony P. Adamis, Vladimir Bantseev, Yawen Chiang, Jason S. Ehrlich, Signe Erickson, William D. ...> ;Ophthalmology. 2019 Aug 1
58 citations
Factors Associated With Visual Acuity and Central Subfield Thickness Changes When Treating Diabetic Macular Edema With Anti-Vascular Endothelial Growth Factor Therapy:...
Susan B. Bressler, Isoken Odia, Maureen G. Maguire, Dilsher S. Dhoot, Adam R. Glassman, Lee M. Jampol, Dennis M. Marcus, Sharon D. Solomon, Jennifer K. Sun> ;JAMA Ophthalmology. 2019 Apr 1
28 citations
Plasma Vascular Endothelial Growth Factor Concentrations after Intravitreous Anti-Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema.
Lee M. Jampol, Adam R. Glassman, Danni Liu, Lloyd Paul Aiello, Neil M. Bressler, Elia J. Duh, Susan E. Quaggin, John A. Wells, Charles C. Wykoff, David J. Browning, An...> ;Ophthalmology. 2018 Mar 7
135 citations
Effect of Bevacizumab vs Aflibercept on Visual Acuity Among Patients With Macular Edema Due to Central Retinal Vein Occlusion: The SCORE2 Randomized Clinical Trial.
Ingrid U. Scott, Paul C. VanVeldhuisen, Michael S Ip, Barbara A Blodi, Neal Oden, Carl C Awh, Derek Y Kunimoto, Dennis M. Marcus, John J Wroblewski, Jacqueline King> ;JAMA. 2017 May 23
6 citations
INTRAVITREAL AFLIBERCEPT INJECTION FOR CHOROIDAL NEOVASCULARIZATION DUE TO PRESUMED OCULAR HISTOPLASMOSIS SYNDROME: The HANDLE Study.
Brian W. Toussaint, John W. Kitchens, Dennis M. Marcus, Daniel M. Miller, Megan L. Kingdon, Diana M Holcomb, Ken Ivey> ;Retina. 2017 Mar 1
13 citations
Intravitreal Aflibercept Injection in Eyes With Substantial Vision Loss After Laser Photocoagulation for Diabetic Macular Edema: Subanalysis of the VISTA and VIVID Ran...
Charles C. Wykoff, Dennis M. Marcus, Edoardo Midena, Jean-François Korobelnik, Namrata Saroj, Andrea Gibson, Robert Vitti, Alyson J. Berliner, Zinaria Williams Liu, Ol...> ;JAMA Ophthalmology. 2017 Feb 1
2 citations
Intravitreal Aflibercept for Neovascular Polypoidal Choroidal Vasculopathy in a Predominantly Non-Asian Population: RIVAL Results.
Amina Farooq, Heather Frazier, William B Marcus, Chelsea Fechter, Harinderjit Singh, Dennis M. Marcus> ;Ophthalmic Surgery, Lasers & Imaging Retina. 2017 Jan 1
26 citations
Twenty-four–Month Outcomes of the Ranibizumab for Edema of the Macula in Diabetes – Protocol 3 with High Dose (READ-3) Study
Yasir J. Sepah, Mohammad Ali Sadiq, David S. Boyer, David Callanan, Ron P. Gallemore, Michael Bennett, Dennis M. Marcus, Lawrence Halperin, Muhammad Hassan, Peter A. C...> ;Ophthalmology. 2016 Dec 1
16 citations
Ranibizumab 0.3 mg for Persistent Diabetic Macular Edema After Recent, Frequent, and Chronic Bevacizumab: The ROTATE Trial
Chelsea Fechter, Heather Frazier, William B Marcus, Amina Farooq, Harinderjit Singh, Dennis M. Marcus> ;Ophthalmic Surgery, Lasers & Imaging Retina. 2016 Nov 1
273 citations
Intravitreal Aflibercept for Diabetic Macular Edema: 148-Week Results from the VISTA and VIVID Studies
Jeffrey S. Heier, Jean-François Korobelnik, David M. Brown, Ursula Schmidt-Erfurth, Diana V. Do, Edoardo Midena, David S. Boyer, Hiroko Terasaki, Peter K. Kaiser, Denn...> ;Ophthalmology. 2016 Nov 1
26 citations
Month-6 primary outcomes of the READ-3 study (Ranibizumab for Edema of the mAcula in Diabetes-Protocol 3 with high dose).
Diana V. Do, Yasir J. Sepah, David S. Boyer, David Callanan, Ron P. Gallemore, Michael Bennett, Dennis M. Marcus, Lawrence Halperin, Mohammad Ali Sadiq, Nithya Rajagop...> ;Eye. 2015 Jul 31
479 citations
Panretinal Photocoagulation vs Intravitreous Ranibizumab for Proliferative Diabetic Retinopathy: A Randomized Clinical Trial.
Jeffrey G. Gross, Adam R. Glassman, Lee M. Jampol, Seidu Inusah, Lloyd Paul Aiello, Andrew N. Antoszyk, Carl W. Baker, Brian B. Berger, Neil M. Bressler, David J. Brow...> ;JAMA. 2015 Nov 24
384 citations
Intravitreal Aflibercept for Diabetic Macular Edema: 100-Week Results From the VISTA and VIVID Studies.
David M. Brown, Ursula Schmidt-Erfurth, Diana V. Do, Frank G. Holz, David S. Boyer, Edoardo Midena, Jeffrey S. Heier, Hiroko Terasaki, Peter K. Kaiser, Dennis M. Marcu...> ;Ophthalmology. 2015 Oct 1
9 citations
High-dose ranibizumab monotherapy for neovascular polypoidal choroidal vasculopathy in a predominantly non-Asian population.
Dennis M. Marcus, H Singh, Chelsea Fechter, D P Chamberlain> ;Eye. 2015 Sep 4
14 citations
Microperimetric assessment of retinal sensitivity in eyes with diabetic macular edema from a phase 2 study of intravitreal aflibercept.
Victor H. Gonzalez, David S. Boyer, Ursula Schmidt-Erfurth, Jeffrey S. Heier, Carmelina Gordon, Matthew S. Benz, Dennis M. Marcus, Nelson R. Sabates, Robert Vitti, Hus...> ;Retina. 2015 Apr 1
63 citations
Monthly versus as-needed ranibizumab injections in patients with retinal vein occlusion: the SHORE study.
Peter A. Campochiaro, Charles C. Wykoff, Michael C. Singer, Robert N. Johnson, Dennis M. Marcus, Linda Yau, Gary Sternberg> ;Ophthalmology. 2014 Dec 1
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Press Mentions

Effect of Initial Management with Aflibercept vs Laser Photocoagulation vs Observation on Vision Loss Among Patients with Diabetic Macular Edema Involving the Center of the Macula and Good Visual AcuityMay 1st, 2019