DevyaniVDeshpandeMD

PubMed

• Ceftriaxone efficacy for Mycobacterium avium complex lung disease in the hollow fiber and translation to sustained sputum culture conversion in patients.
  Devyani Deshpande, Gesham Magombedze, Gunavanthi D Boorgula, Moti Chapagain, Shashikant Srivastava, Tawanda Gumbo> ;The Journal of Infectious Diseases. 2023 Nov 30
• 5 citations
  Hollow-fibre system model of tuberculosis reproducibility and performance specifications for best practice in drug and combination therapy development.
  Tawanda Gumbo, Shashikant Srivastava, Devyani Deshpande, Jotam G Pasipanodya, Alexander Berg, Klaus Romero, David Hermann, Debra Hanna> ;The Journal of Antimicrobial Chemotherapy. 2023 Apr 3
• Minocycline intra-bacterial pharmacokinetic hysteresis as a basis for pharmacologic memory and a backbone for once-a-week pan-tuberculosis therapy.
  Devyani Deshpande, Shashikant Srivastava, Jotam Garaimunashe Pasipanodya, Tawanda Gumbo> ;Frontiers in Pharmacology. 2022 Jan 1
• 5 citations
  Nouveau short-course therapy and morphism mapping for clinical pulmonary Mycobacterium kansasii.
  Shashikant Srivastava, Jann-Yuan Wang, Gesham Magombedze, Moti L. Chapagain, Hung-Ling Huang, Devyani Deshpande, Scott K. Heysell, Jotam G. Pasipanodya, Tawanda Gumbo> ;Antimicrobial Agents and Chemotherapy. 2021 Feb 8
• 6 citations
  Mycobacterium tuberculosis sterilizing activity of faropenem, pyrazinamide and linezolid combination and failure to shorten the therapy duration
  Tawanda Gumbo, Carleton M. Sherman, Devyani Deshpande, Jan-Willem C. Alffenaar, Shashikant Srivastava> ;International Journal of Infectious Diseases. 2021 Feb 5
• 7 citations
  Tedizolid, Faropenem, and Moxifloxacin Combination With Potential Activity Against Nonreplicating Mycobacterium tuberculosis.
  Shashikant Srivastava, Kayle N Cirrincione, Devyani Deshpande, Tawanda Gumbo> ;Frontiers in Pharmacology. 2021 Jan 19
• 11 citations
  Cumulative Fraction of Response for Once- and Twice-Daily Delamanid in Patients with Pulmonary Multidrug-Resistant Tuberculosis.
  Suresh Mallikaarjun, Moti L. Chapagain, Tomohiro Sasaki, Norimitsu Hariguchi, Devyani Deshpande, Shashikant Srivastava, Alexander Berg, Hirota Kuniko, Yusuke Inoue, Ma...> ;Antimicrobial Agents and Chemotherapy. 2020 Dec 16
• 6 citations
  Evaluation of Ceftriaxone Plus Avibactam in an Intracellular Hollow Fiber Model of Tuberculosis: Implications for the Treatment of Disseminated and Meningeal Tuberculo...
  Shashikant Srivastava, Johanna S. van Zyl, Kayle N Cirrincione, Katherine Riley Martin, Tania A Thomas, Devyani Deshpande, Jan-William Alffenaar, James A Seddon, Tawan...> ;The Pediatric Infectious Disease Journal. 2020 Dec 1
• 9 citations
  Duration of pretomanid/moxifloxacin/pyrazinamide therapy compared with standard therapy based on time-to-extinction mathematics.
  Shashikant Srivastava, Devyani Deshpande, Gesham Magombedze, Johanna S. van Zyl, Kayle N Cirrincione, Katherine Riley Martin, Paula Bendet, Alexander Berg, Debra Hanna...> ;The Journal of Antimicrobial Chemotherapy. 2020 Feb 1
• 13 citations
  Minocycline treatment for pulmonary Mycobacterium avium complex disease based on pharmacokinetics/pharmacodynamics and Bayesian framework mathematical models.
  Mike Marvin Ruth, Gesham Magombedze, Tawanda Gumbo, Paula Bendet, Jasper J. N. Sangen, Sanne M.H. Zweijpfenning, Wouter Hoefsloot, Lian J. Pennings, Valerie A. C. M. K...> ;The Journal of Antimicrobial Chemotherapy. 2019 Jul 1
• 12 citations
  Once-a-week tigecycline for the treatment of drug-resistant TB.
  Devyani Deshpande, Gesham Magombedze, Shashikant Srivastava, Paula Bendet, Pooi S Lee, Kayle N Cirrincione, Katherine Riley Martin, Keertan Dheda, Tawanda Gumbo> ;The Journal of Antimicrobial Chemotherapy. 2019 Jun 1
• 17 citations
  Minocycline Immunomodulates via Sonic Hedgehog Signaling and Apoptosis and Has Direct Potency Against Drug-Resistant Tuberculosis.
  Devyani Deshpande, Jotam G. Pasipanodya, Shashikant Srivastava, Katherine R Martin, Shruti Athale, Johanna S. van Zyl, John F. Antiabong, Thearith Koeuth, Pooi S Lee, ...> ;The Journal of Infectious Diseases. 2019 Feb 23
• 54 citations
  Levofloxacin Pharmacokinetics/Pharmacodynamics, Dosing, Susceptibility Breakpoints, and Artificial Intelligence in the Treatment of Multidrug-resistant Tuberculosis
  Devyani Deshpande, Jotam G. Pasipanodya, Stellah G. Mpagama, Paula Bendet, Shashikant Srivastava, Thearith Koeuth, Pooi S Lee, Sujata M. Bhavnani, Paul G. Ambrose, Guy...> ;Clinical Infectious Diseases. 2018 Nov 28
• 15 citations
  Efficacy Versus Hepatotoxicity of High-dose Rifampin, Pyrazinamide, and Moxifloxacin to Shorten Tuberculosis Therapy Duration: There Is Still Fight in the Old Warriors...
  Shashikant Srivastava, Devyani Deshpande, Gesham Magombedze, Tawanda Gumbo> ;Clinical Infectious Diseases. 2018 Nov 28
• 24 citations
  Ethionamide Pharmacokinetics/Pharmacodynamics-derived Dose, the Role of MICs in Clinical Outcome, and the Resistance Arrow of Time in Multidrug-resistant Tuberculosis.
  Devyani Deshpande, Jotam G. Pasipanodya, Stellah G. Mpagama, Shashikant Srivastava, Paula Bendet, Thearith Koeuth, Pooi S Lee, Scott K. Heysell, Tawanda Gumbo> ;Clinical Infectious Diseases. 2018 Nov 28
• 20 citations
  Transformation Morphisms and Time-to-Extinction Analysis That Map Therapy Duration From Preclinical Models to Patients With Tuberculosis: Translating From Apples to Or...
  Gesham Magombedze, Jotam G. Pasipanodya, Shashikant Srivastava, Devyani Deshpande, Marianne E Visser, Emmanuel Chigutsa, Helen McIlleron, Tawanda Gumbo> ;Clinical Infectious Diseases. 2018 Nov 28
• 22 citations
  Gatifloxacin Pharmacokinetics/Pharmacodynamics-based Optimal Dosing for Pulmonary and Meningeal Multidrug-resistant Tuberculosis.
  Devyani Deshpande, Jotam G. Pasipanodya, Shashikant Srivastava, Paula Bendet, Thearith Koeuth, Sujata M. Bhavnani, Paul G. Ambrose, Wynand Smythe, Helen McIlleron, Guy...> ;Clinical Infectious Diseases. 2018 Nov 28
• 36 citations
  d-Cycloserine Pharmacokinetics/Pharmacodynamics, Susceptibility, and Dosing Implications in Multidrug-resistant Tuberculosis: A Faustian Deal
  Devyani Deshpande, Jan-Willem C. Alffenaar, Claudio U. Köser, Keertan Dheda, Moti L. Chapagain, Noviana Simbar, Thomas B. Schön, Marieke G G Sturkenboom, Helen McIller...> ;Clinical Infectious Diseases. 2018 Nov 28
• 23 citations
  The Sterilizing Effect of Intermittent Tedizolid for Pulmonary Tuberculosis.
  Shashikant Srivastava, Devyani Deshpande, Eric L. Nuermberger, Pooi S Lee, Kayle N Cirrincione, Keertan Dheda, Tawanda Gumbo> ;Clinical Infectious Diseases. 2018 Nov 28
• 16 citations
  Multiparameter Responses to Tedizolid Monotherapy and Moxifloxacin Combination Therapy Models of Children With Intracellular Tuberculosis.
  Devyani Deshpande, Shashikant Srivastava, Eric L. Nuermberger, Thearith Koeuth, Katherine Riley Martin, Kayle N Cirrincione, Pooi S Lee, Tawanda Gumbo> ;Clinical Infectious Diseases. 2018 Nov 28
• 10 citations
  Artificial intelligence–derived 3-Way Concentration-dependent Antagonism of Gatifloxacin, Pyrazinamide, and Rifampicin During Treatment of Pulmonary Tuberculosis
  Jotam G. Pasipanodya, Wynand Smythe, Corinne Merle, Piero Olliaro, Devyani Deshpande, Gesham Magombedze, Helen McIlleron, Tawanda Gumbo> ;Clinical Infectious Diseases. 2018 Nov 28
• 27 citations
  Antibacterial and Sterilizing Effect of Benzylpenicillin in Tuberculosis.
  Devyani Deshpande, Shashikant Srivastava, Paula Bendet, Katherine Riley Martin, Kayle N Cirrincione, Pooi S Lee, Jotam G. Pasipanodya, Keertan Dheda, Tawanda Gumbo> ;Antimicrobial Agents and Chemotherapy. 2017 Nov 27
• 81 citations
  Systematic review and meta-analyses of the effect of chemotherapy on pulmonary Mycobacterium abscessus outcomes and disease recurrence
  Jotam G. Pasipanodya, Deborah Ogbonna, Beatriz E. Ferro, Gesham Magombedze, Shashikant Srivastava, Devyani Deshpande, Tawanda Gumbo> ;Antimicrobial Agents and Chemotherapy. 2017 Nov 1
• 31 citations
  Tedizolid is highly bactericidal in the treatment of pulmonary Mycobacterium avium complex disease.
  Devyani Deshpande, Shashikant Srivastava, Jotam G. Pasipanodya, Pooi S Lee, Tawanda Gumbo> ;The Journal of Antimicrobial Chemotherapy. 2017 Sep 1
• 11 citations
  Failure of the azithromycin and ethambutol combination regimen in the hollow-fibre system model of pulmonary Mycobacterium avium infection is due to acquired resistance.
  Shashikant Srivastava, Devyani Deshpande, Tawanda Gumbo> ;The Journal of Antimicrobial Chemotherapy. 2017 Sep 1
• Join now to see all