DouglasEugeneGaasterlandMD

Ophthalmology • Colonial Beach, VA

Glaucoma Related

Retired: Eye Doctors of Washington; glaucoma and general eye care and management

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Office
Retired from clinical care; continued participation in glaucoma genetics studies.
Colonial Beach, VA 22443
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Education & Training

NIH Clinical Center1971
Yale-New Haven Medical CenterResidency, Ophthalmology, 1970
Yale-New Haven Medical CenterResidency, Ophthalmology, 1966 - 1969
Johns Hopkins University/Bayview Medical CenterInternship, Internal Medicine, 1965 - 1966
Johns Hopkins University School of MedicineClass of 1965

Certifications & Licensure

DC State Medical License 1984 - 2013
VA State Medical License 1995 - 2012
MD State Medical License 1969 - 2012
American Board of Ophthalmology Ophthalmology

Awards, Honors, & Recognition

Member, Emeritus American Ophthalmological Society
Super Doctor SuperDoctors.com

Clinical Trials

Ocular Hypertension Treatment Study (OHTS) Start of enrollment: 1994 Feb 01
Completed
Phase 3
Advanced Glaucoma Intervention Study (AGIS) Start of enrollment: 1988 Apr 01
Unknown status
Phase 3

Publications & Presentations

PubMed

38 citations
Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry.
, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,...> ;JAMA. 2019 Nov 5
23 citations
Association of a Primary Open-Angle Glaucoma Genetic Risk Score With Earlier Age at Diagnosis.
Baojian Fan, Jessica N. Cooke Bailey, Robert P. Igo, Jae H. Kang, Tahani Boumenna, Murray H. Brilliant, Donald L. Budenz, John H. Fingert, Terry Gaasterland, Douglas E...> ;JAMA Ophthalmology. 2019 Oct 1
48 citations
Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases
Adriana I Iglesias, Aniket Mishra, Veronique Vitart, Yelena Bykhovskaya, René Höhn, Henriët Springelkamp, Gabriel Cuellar-Partida, Puya Gharahkhani, Jessica N. Cooke B...> ;Nature Communications. 2018 May 14
6 citations
Family-based genome-wide association study of south Indian pedigrees supports WNT7B as a central corneal thickness locus
Baojian Fan, Xueli Chen, Nisha Sondhi, P. Ferdinamarie Sharmila, Nagasamy Soumittra, Sarangapani Sripriya, Srinivasan Sacikala, Rashima Asokan, David S. Friedman, Loui...> ;Investigative Ophthalmology & Visual Science. 2018 May 1
26 citations
Analysis combining correlated glaucoma traits identifies five new risk loci for open-angle glaucoma
Puya Gharahkhani, Kathryn P. Burdon, Jessica N. Cooke Bailey, Alex W. Hewitt, Matthew Law, Louis R. Pasquale, Jae H. Kang, Jonathan L. Haines, Emmanuelle Souzeau, Tige...> ;Scientific Reports. 2018 Feb 15
30 citations
Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility
Sumana R Chintalapudi, Doaa Nabih Maria, Xiang Di Wang, Jessica N. Cooke Bailey, R. Rand Allingham, Murray H. Brilliant, D. L. Budenz, John H. Fingert, Douglas E. Gaas...> ;Nature Communications. 2017 Nov 24
5 citations
Age at natural menopause genetic risk score in relation to age at natural menopause and primary open-angle glaucoma in a US-based sample.
Louis R. Pasquale, Hugues Aschard, Jae H. Kang, Jessica N. Cooke Bailey, Sara Lindström, Daniel I. Chasman, William G. Christen, R. Rand Allingham, Allison E. Ashley-K...> ;Menopause. 2017 Feb 1
37 citations
Assessing the Association of Mitochondrial Genetic Variation With Primary Open-Angle Glaucoma Using Gene-Set Analyses
Anthony P Khawaja, Jessica N. Cooke Bailey, Jae H. Kang, R. Rand Allingham, Michael A. Hauser, Murray H. Brilliant, Donald L. Budenz, William G. Christen, John H. Fing...> ;Investigative Ophthalmology & Visual Science. 2016 Sep 1
34 citations
A common variant in MIR182 is associated with primary open-angle glaucoma in the NEIGHBORHOOD consortium
Yutao Liu, Jessica N. Cooke Bailey, Inas Helwa, W. Michael Dismuke, Jingwen Cai, Michelle Drewry, Murray H. Brilliant, Donald L. Budenz, William G. Christen, Daniel I....> ;Investigative Ophthalmology & Visual Science. 2016 Aug 1
166 citations
Genome-wide association analysis identifies TXNRD2 , ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma
Jessica N. Cooke Bailey, Stephanie Loomis, Jae H. Kang, R. Rand Allingham, Puya Gharahkhani, Chiea Chuen Khor, Kathryn P. Burdon, Hugues Aschard, Daniel I. Chasman, Ro...> ;Nature Genetics. 2016 Feb 1
78 citations
A common variant near TGFBR3 is associated with primary open angle glaucoma
Zheng Li, R. Rand Allingham, Masakazu Nakano, Liyun Jia, Yuhong Chen, Yoko Ikeda, Baskaran Mani, Li Jia Chen, Changwon Kee, David F. Garway-Heath, Sarangapani Sripriya...> ;Human Molecular Genetics. 2015 Jul 1
23 citations
DNA copy number variants of known glaucoma genes in relation to primary open-angle glaucoma.
Yutao Liu, Melanie E. Garrett, Brian L. Yaspan, Jessica N. Cooke Bailey, Stephanie Loomis, Murray H. Brilliant, Donald L. Budenz, William G. Christen, John H. Fingert,...> ;Investigative Ophthalmology & Visual Science. 2014 Nov 20
27 citations
Hypothesis-independent pathway analysis implicates GABA and Acetyl-CoA metabolism in primary open-angle glaucoma and normal-pressure glaucoma
Jessica N. Cooke Bailey, Brian L. Yaspan, Louis R. Pasquale, Michael A. Hauser, Jae H. Kang, Stephanie Loomis, Murray H. Brilliant, Donald L. Budenz, William G. Christ...> ;Human Genetics. 2014 Jul 19
78 citations
Discovery and Functional Annotation of SIX6 Variants in Primary Open-Angle Glaucoma
Megan U. Carnes, Yangfan P. Liu, R. Rand Allingham, Benjamin T. Whigham, Shane J. Havens, Melanie E. Garrett, Chunyan Qiao, Nicholas Katsanis, Janey L. Wiggs, Louis R....> ;Plos Genetics. 2014 May 1
75 citations
Association of CAV1/CAV2 Genomic Variants with Primary Open-Angle Glaucoma Overall and by Gender and Pattern of Visual Field Loss
Stephanie Loomis, Jae H. Kang, Robert N. Weinreb, Brian L. Yaspan, Jessica N. Cooke Bailey, Douglas E. Gaasterland, Terry Gaasterland, Richard K. Lee, Paul R. Lichter,...> ;Ophthalmology. 2014 Feb 1
11 citations
Vascular tone pathway polymorphisms in relation to primary open-angle glaucoma
Jae H. Kang, Stephanie Loomis, Brian L. Yaspan, Jessica N. Cooke Bailey, Robert N. Weinreb, Richard K. Lee, Paul R. Lichter, D. L. Budenz, Yutao Liu, Tony Realini, Dou...> ;Eye. 2014 Jan 1
58 citations
Investigation of known genetic risk factors for primary open angle glaucoma in two populations of African ancestry.
Yutao Liu, Michael A. Hauser, Stephen Akafo, Xuejun Qin, Shiroh Miura, Jason Gibson, Joshua Wheeler, Douglas E. Gaasterland, Pratap Challa, Leon W. Herndon, Robert Rit...> ;Investigative Ophthalmology & Visual Science. 2013 Sep 17
46 citations
The NEIGHBOR consortium primary open-angle glaucoma genome-wide association study: rationale, study design, and clinical variables.
Janey L. Wiggs, Michael A. Hauser, Wael Abdrabou, Robert Rand Allingham, Donald L. Budenz, E. DelBono, David S. Friedman, Jae H. Kang, Douglas E. Gaasterland, Terry Ga...> ;Journal of Glaucoma. 2013 Sep 1
40 citations
Estrogen pathway polymorphisms in relation to primary open angle glaucoma: An analysis accounting for gender from the United States
Louis R. Pasquale, Stephanie Loomis, Robert N. Weinreb, Jae H. Kang, Brian L. Yaspan, Jessica N. Cooke Bailey, Douglas E. Gaasterland, Terry Gaasterland, Richard K. Le...> ;Molecular Vision. 2013 Jul 12
61 citations
CDKN2B-AS1 Genotype – Glaucoma Feature Correlations in Primary Open-Angle Glaucoma Patients from the United States
Louis R. Pasquale, Stephanie Loomis, Jae H. Kang, Brian L. Yaspan, Wael Abdrabou, Donald L. Budenz, Teresa C. Chen, E. DelBono, David S. Friedman, Douglas E. Gaasterla...> ;American Journal of Ophthalmology. 2013 Feb 1
39 citations
Genome-wide analysis of central corneal thickness in primary open-angle glaucoma cases in the NEIGHBOR and GLAUGEN consortia.
Megan Ulmer, Jun Li, Brian L. Yaspan, Ayse Bilge Ozel, Julia E. Richards, Sayoko E. Moroi, Felicia Hawthorne, Donald L. Budenz, David S. Friedman, Douglas E. Gaasterla...> ;Investigative Ophthalmology & Visual Science. 2012 Jul 1
229 citations
Common Variants at 9p21 and 8q22 Are Associated with Increased Susceptibility to Optic Nerve Degeneration in Glaucoma
Janey L. Wiggs, Brian L. Yaspan, Michael A. Hauser, Jae H. Kang, R. Rand Allingham, Lana M. Olson, Wael Abdrabou, Baojian Fan, Dan Y. Wang, Wendy Brodeur, Donald L. Bu...> ;Plos Genetics. 2012 Apr 26
31 citations
GALC Deletions Increase the Risk of Primary Open-Angle Glaucoma: The Role of Mendelian Variants in Complex Disease
Yutao Liu, Jason Gibson, Joshua Wheeler, Lydia Coulter Kwee, Cecile Santiago-Turla, Stephen Akafo, Paul R. Lichter, Douglas E. Gaasterland, Sayoko E. Moroi, Pratap Cha...> ;Plos One. 2011 Nov 4
42 citations
Asymmetries and visual field summaries as predictors of glaucoma in the ocular hypertension treatment study
Richard A. Levine, Shaban Demirel, Juanjuan Fan, John L. Keltner, Chris A. Johnson, Michael A. Kass, Donald L. Budenz, Francisco Fantes, Steven J. Gedde, Richard K. Pa...> ;Investigative Ophthalmology & Visual Science. 2006 Sep 1
58 citations
Pointwise linear regression for evaluation of visual field outcomes and comparison with the advanced glaucoma intervention study methods.
Kouros Nouri-Mahdavi, Joseph Caprioli, Anne L. Coleman, D. Hoffman, Douglas E. Gaasterland> ;Archives of Ophthalmology. 2005 Feb 1
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