DouglasGRirieMDPh.D.

Anesthesiology • Winston Salem, NC

Cardiothoracic Anesthesiology, Pain Medicine, Pediatric Anesthesiology

Professor and Section Head, Pediatric Anesthesiology, Wake Forest University School of Medicine

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Office
Medical Center Blvd
Winston Salem, NC 27157
Phone+1 336-716-2255
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Education & Training

Louisiana State UniversityMHA, 2016 - 2018
Wake Forest UniversityPh.D., Molecular Medicine, 2004 - 2008
Children's Hospital/Harvard Medical SchoolFellowship, Pediatric Anesthesiology, 1994 - 1995
Wake Forest University School of MedicineResidency, Anesthesiology, 1991 - 1994
Cambridge Health AllianceInternship, Transitional Year, 1990 - 1991
University of North Carolina at Chapel Hill School of MedicineClass of 1990

Certifications & Licensure

NC State Medical License 1991 - 2025
MA State Medical License 1994 - 1999
American Board of Anesthesiology Anesthesiology
American Board of Anesthesiology Pediatric Anesthesiology

Awards, Honors, & Recognition

Top MD Consumers Checkbook

Clinical Trials

Pain Effect on Attention Using an Ipad Game App Start of enrollment: 2016 May 15
Recruiting
Not Applicable

Publications & Presentations

PubMed

Effects of multiple anesthetic exposures on rhesus macaque brain development: a longitudinal structural MRI analysis.
Jeongchul Kim, Richard Barcus, Megan E Lipford, Hongyu Yuan, Douglas G Ririe, Youngkyoo Jung, Roza M Vlasova, Martin Styner, Michael A Nader, Christopher T Whitlow> ;Cerebral Cortex. 2024 Jan 14
Risk factors for administration of additional reversal following neuromuscular blockade with rocuronium in children: A retrospective case-control study.
Susan R Vishneski, Amit K Saha, Madeline R Fram, Leah B Templeton, Lisa K Lee, Douglas G Ririe, Eduardo Javier Goenaga-Diaz, Laura Daniela Smith, Thomas Wesley Templeton> ;Paediatric Anaesthesia. 2022 Aug 1
7 citations
A Painful Beginning: Early Life Surgery Produces Long-Term Behavioral Disruption in the Rat.
Douglas G. Ririe, James C. Eisenach, Thomas J. Martin> ;Frontiers in Behavioral Neuroscience. 2021 Jan 1
1 citations
A comparison of the breathing apparatus deadspace associated with a supraglottic airway and endotracheal tube using volumetric capnography in young children
Eduardo J. Goenaga-Díaz, Lauren Daniela Smith, Shelly H. Pecorella, Timothy E. Smith, Gregory B. Russell, Kathleen Nicole Johnson, Martina G. Downard, Douglas G. Ririe...> ;Korean Journal of Anesthesiology. 2021 Jun 1
3 citations
Nociceptive input after peripheral nerve injury results in cognitive impairment and alterations in primary afferent physiology in rats.
M. Danilo Boada, Douglas G. Ririe, Conner W Martin, Salem J Martin, Susy A. Kim, James C. Eisenach, Thomas J. Martin> ;Pain. 2020 May 1
8 citations
Recovery from nerve injury induced behavioral hypersensitivity in rats parallels resolution of abnormal primary sensory afferent signaling.
M. Danilo Boada, Thomas J. Martin, Renee Parker, Timothy T. Houle, James C. Eisenach, Douglas G. Ririe> ;Pain. 2020 May 1
14 citations
Assessment of Common Criteria for Awake Extubation in Infants and Young Children.
T. Wesley Templeton, Eduardo J. Goenaga-Díaz, Martina G. Downard, Christopher J. McLouth, Timothy E. Smith, Leah B. Templeton, Shelly H. Pecorella, Dudley E. Hammon, J...> ;Anesthesiology. 2019 Oct 1
9 citations
Incisional Nociceptive Input Impairs Attention-related Behavior and Is Associated with Reduced Neuronal Activity in the Prefrontal Cortex in Rats
Douglas G. Ririe, M. Danilo Boada, Megan K. MacGregor, Salem J Martin, Tracy J. Strassburg, Susy A. Kim, James C. Eisenach, Thomas J. Martin> ;Anesthesiology. 2018 Oct 1
2 citations
An inconvenient truth: Supraglottic devices can lead to potentially significant increases in the apparatus dead space in the anesthetized infant.
T. Wesley Templeton, Eduardo J. Goenaga-Díaz, Leah B. Templeton, Douglas G. Ririe> ;Paediatric Anaesthesia. 2018 Jul 1
1 citations
An in vitro analysis of the dead space in 5 supraglottic airway devices intended for use in small children and infants.
Thomas Wesley Templeton, Eduardo J. Goenaga-Díaz, Leah B. Templeton, Douglas G. Ririe> ;Paediatric Anaesthesia. 2018 Jun 1
13 citations
An initial experience with an Extraluminal EZ-Blocker® : A new alternative for 1-lung ventilation in pediatric patients.
Thomas Wesley Templeton, Leah B. Templeton, Ann E. Lawrence, Leah M. Sieren, Martina G. Downard, Douglas G. Ririe> ;Paediatric Anaesthesia. 2018 Feb 11
12 citations
Antinociception induced by a novel α 2A adrenergic receptor agonist in rodents acute and chronic pain models
Roberto T. Sudo, Rachel Vieiralves do Amaral, Carlos Eduardo da Silva Monteiro, Ivan da Rocha Pitta, Maria do Carmo Alves de Lima, Guilherme C Montes, Douglas G. Ririe...> ;European Journal of Pharmacology. 2017 Nov 15
6 citations
Post-discharge hyperpolarization is an endogenous modulatory factor limiting input from fast-conducting nociceptors (AHTMRs).
M. Danilo Boada, Douglas G. Ririe, James C. Eisenach> ;Molecular Pain. 2017 Aug 21
9 citations
Assessment of Behavioral Disruption in Rats with Abdominal Inflammation Using Visual Cue Titration and the Five-choice Serial-reaction Time Task.
Thomas J. Martin, Tracy J. Strassburg, Amanda Grigg, Susy A. Kim, Douglas G. Ririe, James C. Eisenach> ;Anesthesiology. 2017 Aug 1
3 citations
Audiovisual Distraction Increases Prefrontal Cortical Neuronal Activity and Impairs Attentional Performance in the Rat
Douglas G. Ririe, M. Danilo Boada, Benjamin S Schmidt, Salem J Martin, Susy A. Kim, Thomas J. Martin> ;Journal of Experimental Neuroscience. 2017 Apr 6
4 citations
A comparison of 3 ventilation strategies in children younger than 1 year using a Proseal laryngeal mask airway: a randomized controlled trial
T. Wesley Templeton, Lauren K. Hoke, Leah B. Templeton, Douglas G. Ririe, Danielle M. Rose, Yvon F. Bryan> ;Journal of Clinical Anesthesia. 2016 Dec 1
13 citations
Nerve injury induced activation of fast-conducting high threshold mechanoreceptors predicts non-reflexive pain related behavior.
M. Danilo Boada, Thomas J. Martin, Douglas G. Ririe> ;Neuroscience Letters. 2016 Oct 6
6 citations
Mechanical sensibility of nociceptive and non-nociceptive fast-conducting afferents is modulated by skin temperature.
M. Danilo Boada, James C. Eisenach, Douglas G. Ririe> ;Journal of Neurophysiology. 2016 Jan 1
5 citations
How long does incisional pain last: early life vulnerability could make it last a lifetime.
Douglas G. Ririe> ;Anesthesiology. 2015 Jun 1
16 citations
Assessment of attention threshold in rats by titration of visual cue duration during the five choice serial reaction time task
Thomas J. Martin, Amanda Grigg, Susy A. Kim, Douglas G. Ririe, James C. Eisenach> ;Journal of Neuroscience Methods. 2015 Feb 15
27 citations
Nerve injury induces a new profile of tactile and mechanical nociceptor input from undamaged peripheral afferents
M. Danilo Boada, Silvia Gutierrez, Carol A. Aschenbrenner, Timothy T. Houle, Ken-ichiro Hayashida, Douglas G. Ririe, James C. Eisenach> ;Journal of Neurophysiology. 2015 Jan 1
44 citations
Fast Conducting Mechanoreceptors Contribute to Withdrawal Behavior in Normal and Nerve Injured Rats
M. Danilo Boada, Thomas J. Martin, Christopher M. Peters, Ken-ichiro Hayashida, Michael H. Harris, Timothy T. Houle, Edward S. Boyden, James C. Eisenach, Douglas G. Ririe> ;Pain. 2014 Dec 1
18 citations
Nociceptor-selective peripheral nerve block induces delayed mechanical hypersensitivity and neurotoxicity in rats.
Christopher M. Peters, Douglas G. Ririe, Timothy T. Houle, Carol A. Aschenbrenner, James C. Eisenach> ;Anesthesiology. 2014 Apr 1
21 citations
Skin incision-induced receptive field responses of mechanosensitive peripheral neurons are developmentally regulated in the rat
M. Danilo Boada, Silvia Gutierrez, Kelly A. Giffear, James C. Eisenach, Douglas G. Ririe> ;Journal of Neurophysiology. 2012 Aug 15
95 citations
Parameters of care for craniosynostosis.
Joseph G. McCarthy, Stephen M. Warren, Joseph Bernstein, Whitney Burnett, Michael L. Cunningham, Jane C. Edmond, Alvaro A. Figueroa, Kathleen A. Kapp-Simon, Brian I. L...> ;The Cleft Palate-Craniofacial Journal. 2012 Jan 1
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Lectures

An Analysis of Laryngoscope Bulb Heat: Should There Be Concern?
Wake Forest School of Medicine, Winston-Salem, NC, USA. - 10/12/2014

Grant Support

Development Of An Optical Silencer Based Genetic Therapy For Neuropathic PainNational Institute Of Neurological Disorders And Stroke2011
Neurophysiologic Development Responses To SurgeryNational Institute Of General Medical Sciences2004–2007