EPatrickMitchellDO

PubMed

• A phase II trial of perifosine in locally advanced, unresectable, or metastatic pancreatic adenocarcinoma.
  Marsh, R.W., Rocha Lima, C.M., Levy, D.E., Mitchell, E.P., Rowland, K.M., Benson, A.B.> ;Am J Clin Oncol. 2007 Feb
• Irinotecan in preoperative combined-modality therapy for locally advanced rectal cancer.
  Mitchell, E.P.> ;Oncology (Williston Park). 2000 Dec
• Oxaliplatin with 5-FU or as a single agent in advanced/metastatic colorectal cancer.
  Mitchell, E.P.> ;Oncology (Williston Park). 2000 Dec
• Phase I clinical/pharmacokinetic and pharmacodynamic trial of the c-raf-1 antisense oligonucleotide ISIS 5132 (CGP 69846A).
  Stevenson, J.P., Yao, K.S., Gallagher, M., Friedland, D., Mitchell, E.P., Cassella, A., Monia, B., Kwoh, T.J., Yu, R., Holmlund, J., Dorr, F.A., O'Dwyer, P.J.> ;J Clin Oncol. 1999 Jul
• Role of carcinoembryonic antigen in the management of advanced colorectal cancer.
  Mitchell, E.P.> ;Semin Oncol. 1998 Oct
• Advances in the treatment of metastatic colorectal cancer.
  Mitchell, E.P.> ;Surg Technol Int. 1998
• Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states.
  Mitchell, E.P., Withers, S.G., Ermert, P., Vasella, A.T., Garman, E.F., Oikonomakos, N.G., Johnson, L.N.> ;Biochemistry. 1996 Jun 11
• 37 citations
  Glucose analogue inhibitors of glycogen phosphorylase: from crystallographic analysis to drug prediction using GRID force-field and GOLPE variable selection.
  Kimberly A. Watson, E. P. Mitchell, Louise N. Johnson, Gabriele Cruciani, Jong Chan Son, C. J. F. Bichard, George W. J. Fleet, Nikos G. Oikonomakos, Maria Kontou, Spyr...> ;Acta Crystallographica. Section D, Biological Crystallography. 1995 Jul 1
• 6 citations
  The design of potential antidiabetic drugs: experimental investigation of a number of β-D-glucose analogue inhibitors of glycogen phosphorylase
  Nikos G. Oikonomakos, Maria Kontou, Spyros E. Zographos, H. S. Tsitoura, Louise N. Johnson, K.A. Watson, E. P. Mitchell, George W. J. Fleet, Jong Chan Son, C. J. F. Bi...> ;European Journal of Drug Metabolism and Pharmacokinetics. 1994 Sep 1
• 74 citations
  Design of inhibitors of glycogen phosphorylase: a study of alpha- and beta-C-glucosides and 1-thio-beta-D-glucose compounds.
  Kimberly A. Watson, E. P. Mitchell, Louise N. Johnson, Jong Chan Son, C. J. F. Bichard, Michael Glen Orchard, George W. J. Fleet, N.G. Oikonomakos, Demetres D. Leonida...> ;Biochemistry. 1994 May 17
• 82 citations
  Immunoscintigraphy performed with In-111-labeled CYT-103 in the management of colorectal cancer: comparison with CT.
  Collier Bd, Hani Abdel-Nabi, R J Doerr, S J Harwood, J Olsen, E H Kaplan, G G Winzelberg, S J Grossman, D N Krag, E P Mitchell> ;Radiology. 1992 Oct 1
• The nature of the di-iron site in the bacterioferritin from Desulfovibrio desulfuricans.
  Macedo, S., Romão, C. V., Mitchell, E., Matias, P. M., Liu, M. Y., Xavier, A. V., LeGall, J., Teixeira, M., Lindley, P., Carrondo, M. A.> ;Nat Struct Biol. 2003 Apr
• Phase II studies of methyl glyoxal bis-guanylhydrazone (NSC 32946) in carcinoma of the colon and lung.
  Killen, J. Y., Mitchell, E. P., Hoth, D. F., Willis, L. L., Gullo, J. J., Smith, F. P., Schein, P. S., Woolley, P. V.> ;Cancer. 1982 Oct 1
• Phase II study of PCNU in colorectal carcinoma.
  Mitchell, E. P., Killen, J. Y., Smith, F. P., Willis, L. L., Schein, P. S., Woolley, P. V.> ;Cancer Treat Rep. 1981 Nov 01
• Isolectins I-A and I-B of Griffonia (Bandeiraea) simplicifolia. Crystal structure of metal-free GS I-B(4) and molecular basis for metal binding and monosaccharide spec...
  Lescar, J., Loris, R., Mitchell, E., Gautier, C., Chazalet, V., Cox, V., Wyns, L., Pérez, S., Breton, C., Imberty, A.> ;J Biol Chem. 2002 Feb 22
• Immunoscintigraphy with 111In-satumomab pendetide in patients with colorectal adenocarcinoma: performance and impact on clinical management.
  Corman, M. L., Galandiuk, S., Block, G. E., Prager, E. D., Weiner, G. J., Kahn, D., Abdel-Nabi, H., Mitchell, E. P., Pascucci, V. L., Maroli, A. N.> ;Dis Colon Rectum. 1994 Feb
• Carcinoma of the anal region.
  Mitchell, E. P.> ;Semin Oncol. 1988 Apr
• Crystal structure of fungal lectin: six-bladed beta-propeller fold and novel fucose recognition mode for Aleuria aurantia lectin.
  Wimmerova, M., Mitchell, E., Sanchez, J. F., Gautier, C., Imberty, A.> ;J Biol Chem. 2003 Jul 18
• The crystal structure of the Dps2 from Deinococcus radiodurans reveals an unusual pore profile with a non-specific metal binding site.
  Cuypers, M. G., Mitchell, E. P., Romão, C. V., McSweeney, S. M.> ;J Mol Biol. 2007 Aug 17
• The complex of Sphingomonas elodea ATCC 31461 glucose-1-phosphate uridylyltransferase with glucose-1-phosphate reveals a novel quaternary structure, unique among nucle...
  Aragão, D., Fialho, A. M., Marques, A. R., Mitchell, E. P., Sá-Correia, I., Frazão, C.> ;J Bacteriol. 2007 Jun
• Unusual entropy-driven affinity of Chromobacterium violaceum lectin CV-IIL toward fucose and mannose.
  Pokorná, M., Cioci, G., Perret, S., Rebuffet, E., Kostlánová, N., Adam, J., Gilboa-Garber, N., Mitchell, E. P., Imberty, A., Wimmerová, M.> ;Biochemistry. 2006 Jun 20
• Engineering of PA-IIL lectin from Pseudomonas aeruginosa - Unravelling the role of the specificity loop for sugar preference.
  Adam, J., Pokorná, M., Sabin, C., Mitchell, E. P., Imberty, A., Wimmerová, M.> ;BMC Struct Biol. 2007
• Structural basis of calcium and galactose recognition by the lectin PA-IL of Pseudomonas aeruginosa.
  Cioci, G., Mitchell, E. P., Gautier, C., Wimmerová, M., Sudakevitz, D., Pérez, S., Gilboa-Garber, N., Imberty, A.> ;FEBS Lett. 2003 Dec 4
• Biochemical and structural analysis of Helix pomatia agglutinin. A hexameric lectin with a novel fold.
  Sanchez, J. F., Lescar, J., Chazalet, V., Audfray, A., Gagnon, J., Alvarez, R., Breton, C., Imberty, A., Mitchell, E. P.> ;J Biol Chem. 2006 Jul 21
• Gastrointestinal toxicity of chemotherapeutic agents.
  Mitchell, E. P.> ;Semin Oncol. 1992 Oct
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