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Office
Route 206 and Province Line Road
Princeton, NJ 08543- Is this information wrong?
Summary
- I am an infectious disease-trained physician-scientist with deep translational and clinical experience in hepatology, immunology, infectious diseases, autoimmunity and fibrosis. Broad clinical research experience in early and late stage drug development, including immunopathogenesis basic/translational research, target identification, biomarker identification, Phase 0-4 trials, and FDA registration.
Education & Training
Rockefeller UniversityMSc, Clinical and Translational Investigation, 2008 - 2009
NYU Grossman School of MedicineFellowship, Infectious Disease, 2002 - 2004- NYU Grossman School of MedicineResidency, Internal Medicine, 1999 - 2003
University of Alabama School of MedicineClass of 1999- University of ChicagoBA, Economics, Cum Laude, 1989 - 1993
Certifications & Licensure
NY State Medical License 2001 - 2024
Clinical Trials
- Characterization of Clonal B Cell Populations in HCV Infection Start of enrollment: 2007 Jan 01
- Pilot Study to Assess Gut Mucosal B Cells in Individuals With HCV and HIV Start of enrollment: 2009 Nov 01
Publications & Presentations
PubMed
- 12 citationsElbasvir/Grazoprevir in People With Hepatitis C Genotype 1 Infection and Child-Pugh Class B Cirrhosis: The C-SALT Study.Ira M. Jacobson, Fred Poordad, Roberto J. Firpi-Morell, Gregory T. Everson, Elizabeth C. Verna, S. Bhanja, Peggy Hwang, Luzelena Caro, Michael N. Robertson, Edgar D. C...> ;Clinical and Translational Gastroenterology. 2019 Mar 28
- 157 citationsPegbelfermin (BMS-986036), PEGylated FGF21, in Patients with Obesity and Type 2 Diabetes: Results from a Randomized Phase 2 Study.Edgar D. Charles, Brent A. Neuschwander-Tetri, Juan P. Frias, Sudeep Kundu, Yi Luo, Giridhar S. Tirucherai, Rose C. Christian> ;Obesity. 2019 Jan 1
- 309 citationsPegbelfermin (BMS-986036), a PEGylated fibroblast growth factor 21 analogue, in patients with non-alcoholic steatohepatitis: a randomised, double-blind, placebo-contro...Arun J. Sanyal, Edgar D. Charles, Brent A. Neuschwander-Tetri, Rohit Loomba, Stephen A. Harrison, Manal F. Abdelmalek, Eric Lawitz, Dina Halegoua-DeMarzio, Sudeep Kund...> ;Lancet. 2018 Dec 22
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Journal Articles
- The Lancet Child & Adolescent HealthArun Sanyal, Stephen A Harrison, Edgar D Charles, Stephanie Noviello, Manal F Abdelmalek, Eric J Lawitz, Rohit Loomba, The Lancet
Abstracts/Posters
- A Phase 2 Study of BMS-986036 (Pegylated FGF21) for 12 Weeks in Obese Adults with Type 2 Diabetes Mellitus (T2DM) and a High Prevalence of Fatty LiverEdgar D. Charles, Brent A. Neuschwander-Tetri, Yi Luo, Chunyu Kate Wu, Rose Christian, American Association for the Study of Liver Disease, Boston, 11/13/2016
- A Phase 1 Study of BMS-986171 (Pegylated FGF21) in Healthy Obese SubjectsChunyu Kate Wu1, Edgar D. Charles, Anh Bui, Rose Christian, Malaz AbuTarif, American Association for the Study of Liver Disease, Boston, 11/12/2016
- A Phase 1 Study of BMS-986036 (Pegylated FGF21) in Healthy Obese SubjectsEdgar D. Charles, Linda Morrow, Marcus Hompesch, Yi Luo, Chunyu Kate Wu, Rose Christian, American Association for the Study of Liver Disease, Boston, 10/12/2016
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Grant Support
- The Pathogenesis Of Autoimmunity In Hepatitis C Virus InfectionNational Institute Of Allergy And Infectious Diseases2008–2012
Hospital Affiliations
VA NY Harbor Healthcare System, Manhattan CampusBrooklyn, New York
Veterans Affairs New York Harbor Healthcare SystemBrooklyn, New York
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