EdgarTurnerOvertonMD

Infectious Disease • Birmingham, AL

Assistant Professor, Medicine, University of Alabama School of Medicine

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Office
908 20th St S
Birmingham, AL 35294
Phone(205) 934-5191
Fax(314) 975-6027
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Education & Training

Washington UniversityFellowship, Infectious Disease, 2002 - 2004
University of Alabama Medical CenterResidency, Internal Medicine, 1999 - 2002
University of Tennessee College of MedicineClass of 1999

Certifications & Licensure

AL State Medical License 2001 - 2021
American Board of Internal Medicine Internal Medicine

Clinical Trials

Effects of the Probiotic Visbiome Extra Strength on Gut Microbiome & Immune Activation Markers Start of enrollment: 2016 Mar 01Adriana Andrade, MD, MPH and Edgar T Overton, MD
A Prospective Randomized Controlled Study to Evaluate the Effect of Isotretinoin on Immune Activation Among HIV-1 Infected Subjects With Incomplete CD4+ T Cell Recovery on Suppressive Antiretroviral Therapy (ART) Start of enrollment: 2014 Jul 01Overton, E.T.,Arduino, R.C.,Haas, D.,Tashima, K.T.,Fichtenbaum, C.J.,Gandhi, R.T.,Wohl, D.A.,Sax, P.E.,Luque, A.,Havlir, D.V.,Swaminathan, S.,Kwon, D.,Landovitz, R.,Clifford, D.B.
Randomized, Open-label Phase II Trial to Assess the Safety and Immunogenicity of MVA-BN Smallpox Vaccine in Immunocompromised Subjects With HIV Infection Start of enrollment: 2014 Apr 01Peck, A.,Brown, A.,Walker, D.,Overton, E.T.,Quinn, J.,Franz, J.A.,Spitz, T.,Sauter, W.
FTC/RPV/TDF on T-Cell Activation, CD4 Cell Count, Inflammatory Biomarkers and Viral Reservoir Start of enrollment: 2013 Feb 01Lopez, A.,Luque, A.,Kershaw, A.,Collier, A.,Taiwo, B.,Berzins, B.,Adams, B.,Rio, C.d.,Greisberger, C.,Davis, C.,Marcus, C.,Tripoli, C.A.,Jonsson, C.,Benson, C.A.,Wohl, D.,Havlir, D.V.,Overton, E.T.,Telzak...
A Phase I/II, Two-Staged, Single-Center, Randomized, Double-Blind, Antibody Titer Study to Assess Immunogenicity and Safety of FluMist® Intranasal Influenza Vaccine Administered With and Without a TLR-3 Agonist, Ampligen®. Start of enrollment: 2012 Apr 01Overton, E.T.,Goepfert, P.A.,Strayer, D.R.
A Prospective, Randomized, Double-Blind Phase II Trial of High-Dose Vitamin D and Calcium for Bone Health in HIV-Infected Individuals Initiating Highly Active Antiretroviral Therapy (HAART) Start of enrollment: 2011 Sep 01Baum, J.,Berzins, B.,Brogden, G.,Chang, S.,Cuervo, H.,Downing, M.,Epperson, K.,Flynn, T.,Forcht, J.,Fritsche, J.,Gonzalez, M.,Gothing, J.,Greisberger, C.,Guerrero, M.,Klebert, M.,Kunkel, J.,Lusch, T.,Mans...
A Multicenter, Open-label, Controlled Phase II Study to Evaluate Safety and Immunogenicity of MVA-BN® (IMVAMUNE) Smallpox Vaccine in 18-55 Year Old Naive and Previously Vaccinated HIV Infected Subjects With CD4 Counts >200 - 750/µl. Start of enrollment: 2006 Jun 01Overton, E.T.
Safety and Effectiveness of an Adjuvant in Improving Immune Response to Hepatitis B Virus Vaccine in HIV Infected Individuals Overton, E.(.,Aberg, J.A.
PREPARE (A5361s) Substudy of REPRIEVE (A5332) Todd Brown, MD, PhD and Kristine Erlandson, MD
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Publications & Presentations

PubMed

Long-acting cabotegravir and rilpivirine dosed every 2 months in adults with HIV-1 infection (ATLAS-2M), 48-week results: a randomised, multicentre, open-label, phase ...
Edgar T. Overton, Gary Richmond, Giuliano Rizzardini, Hans Jaeger, Catherine Orrell, Firaya Nagimova, Fritz Bredeek, Miguel García Deltoro, Susan Swindells, Jaime Andr...> ;The Lancet. 2020 Dec 9
Long-Acting Injectable Cabotegravir + Rilpivirine for HIV Maintenance Therapy: Week 48 Pooled Analysis of Phase 3 ATLAS and FLAIR Trials.
Giuliano Rizzardini, Edgar T. Overton, Chloe Orkin, Susan Swindells, Keikawus Arastéh, Miguel de Górgolas Hernández-Mora, Vadim Pokrovsky, Pierre Marie Girard, Shinich...> ;Journal of Acquired Immune Deficiency Syndromes. 2020 Dec 1
One-year Statin Persistence and Adherence in Adults with HIV in the United States
Kaylee B. Crockett, Ying Wen, Edgar T. Overton, Elizabeth A. Jackson, Robert S. Rosenson, Paul Muntner, Lisandro D. Colantonio> ;Journal of Clinical Lipidology. 2020 Nov 11
Direct Acting Antivirals in Hepatitis C-Infected Kidney Transplant Recipients: Associations with Long-term Graft Failure and Patient Mortality.
Goetsch, M. R., Tamhane, A., Overton, E. T., Towns, G. C., Franco, R. A.> ;Pathogens & immunity. 2020 Oct 23
Corrigendum to: Patterns of Antiretroviral Therapy Use and Immunologic Profiles at Enrollment in the REPRIEVE Trial.
Carl J. Fichtenbaum, Heather J. Ribaudo, Jorge Leon-Cruz, Edgar T. Overton, Markella V. Zanni, Carlos Malvestutto, Judith A. Aberg, Emma M. Kileel, Kathleen V. Fitch, ...> ;The Journal of Infectious Diseases. 2020 Oct 17
Alternative strategies of posttransplant influenza vaccination in adult solid organ transplant recipients.
Zaid Haddadin, Karen M. Krueger, Lora D. Thomas, Edgar T. Overton, Michael G. Ison, Natasha Halasa> ;American Journal of Transplantation. 2020 Sep 23
Hepatitis C Among High-Risk Alabamians: Disease Burden and Screening Effectiveness.
Lee, A. B., Karumberia, S., Gilmore, A., Williams, E., Bruner, N., Overton, E. T., Saag, M. S., Franco, R. A.> ;The Journal of infectious diseases. 2020 Sep 3
An Evaluation of Baseline Kidney Function in the REPRIEVE Trial of Pitavastatin in Human Immunodeficiency Virus
Edgar T. Overton, Amy Kantor, Kathleen V. Fitch, Paul Muntner, Khuanchai Supparatpinyo, Mosepele Mosepele, Lerato Mohapi, Sandra W. Cardoso, Sandesh Patil, Marcus V. G...> ;The Journal of Infectious Diseases. 2020 Jul 9
Physical Function Impairment and Frailty in Middle-Aged People Living With Human Immunodeficiency Virus in the REPRIEVE Trial Ancillary Study PREPARE
Triin Umbleja, Todd T. Brown, Edgar T. Overton, Heather J. Ribaudo, Jennifer A. Schrack, Kathleen V. Fitch, Pamela S. Douglas, Steven K. Grinspoon, Sarah Henn, Roberto...> ;The Journal of Infectious Diseases. 2020 Jul 9
Patterns of Antiretroviral Therapy Use and Immunologic Profiles at Enrollment in the REPRIEVE Trial
Carl J. Fichtenbaum, Heather J. Ribaudo, Jorge Leon-Cruz, Edgar T. Overton, Markella V. Zanni, Carlos Malvestutto, Judith A. Aberg, Emma M. Kileel, Kathleen V. Fitch, ...> ;The Journal of Infectious Diseases. 2020 Jul 9
Immune Activation and Inflammation in People With Human Immunodeficiency Virus: Challenging Targets.
Netanya S. Utay, Edgar T. Overton> ;The Journal of Infectious Diseases. 2020 Apr 27
Successful recruitment of a multi-site international randomized placebo-controlled trial in people with HIV with attention to diversity of race and ethnicity: critical...
Kathleen V. Fitch, Emma M. Kileel, Sara E. Looby, Markella V. Zanni, Laura Sanchez, Carl J. Fichtenbaum, Edgar T. Overton, Carlos Malvestutto, Judith A. Aberg, Karin L...> ;HIV research & clinical practice. 2020 Mar 11
Long-Acting Cabotegravir and Rilpivirine after Oral Induction for HIV-1 Infection
Chloe Orkin, Keikawus Arastéh, Miguel de Górgolas Hernández-Mora, Vadim Pokrovsky, Edgar Turner Overton, Pierre-Marie Girard, Shinichi Oka, Sharon Walmsley, Chris Bett...> ;The New England Journal of Medicine. 2020 Mar 4
Sexually transmitted infections and sexual behaviors of men who have sex with men in an American Deep South PrEP clinic.
Gravett, R. M., Westfall, A. O., Overton, E. T., Kudroff, K., Muzny, C. A., Eaton, E. F.> ;International journal of STD & AIDS. 2020 Jan 30
Brief Report: Aging Attenuates the Association Between Coronary Artery Calcification and Bone Loss Among HIV-Infected Persons.
Gerome Escota, Jason V. Baker, Tim Bush, Lois Conley, John T. Brooks, Pragna Patel, William G. Powderly, Rachel M. Presti, Edgar T. Overton> ;Journal of Acquired Immune Deficiency Syndromes. 2019 Sep 1
Rationale and design of the Mechanistic Substudy of the Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE): Effects of pitavastatin on coronary artery disea...
Udo Hoffmann, Michael T. Lu, Devvora Olalere, Elizabeth C. Adami, Michael T. Osborne, Alexander R. Ivanov, John Sukumar Aluru, Saeyun Lee, Nadja Arifovic, Edgar T. Ove...> ;American Heart Journal. 2019 Jun 1
Rationale and design of the Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE).
Steven K. Grinspoon, Kathleen V. Fitch, Edgar T. Overton, Carl J. Fichtenbaum, Markella V. Zanni, Judith A. Aberg, Carlos Malvestutto, Michael T. Lu, Judith S. Currier...> ;American Heart Journal. 2019 Jun 1
Associations of food insecurity and psychosocial measures with diet quality in adults aging with HIV.
Josh Muhammad, Jose R. Fernandez, Olivio J. Clay, Michael S. Saag, Edgar T. Overton, Amanda L. Willig> ;Aids Care-psychological and Socio-medical Aspects of Aids\/hiv. 2019 May 1
Rapid Boosting of HIV-1 Neutralizing Antibody Responses in Humans Following a Prolonged Immunologic Rest Period.
Spearman, P., Tomaras, G. D., Montefiori, D. C., Huang, Y., Elizaga, M. L., Ferrari, G., Alam, S. M., Isaacs, A., Ahmed, H., Hural, J., McElrath, M. J., Ouedraogo, L.,...> ;The Journal of infectious diseases. 2019 Jan 8
Vitamin D does not modulate immune-mediated bone loss during ART initiation.
Michael T. Yin, Ellen S. Chan, Todd T. Brown, Jennifer Kinslow, Jeffrey Martinson, Alan L. Landay, Kathleen Melbourne, Heather J. Ribaudo, Edgar T. Overton, A Study Team> ;Antiviral Therapy. 2019 Jan 1
Alterations in the oral microbiome in HIV-infected participants after antiretroviral therapy administration are influenced by immune status.
Rachel M. Presti, Scott A. Handley, Lindsay Droit, Mahmoud A. Ghannoum, Mark A. Jacobson, Caroline H. Shiboski, Jennifer Webster-Cyriaque, Todd T. Brown, Michael T. Yi...> ;AIDS. 2018 Jun 19
The hidden risk: Incorporating inflammation and HIV serostatus into coronary artery disease screening
Gregory A. Payne, Edgar T. Overton> ;Journal of Nuclear Cardiology. 2018 Jun 1
Immunogenicity and safety of three consecutive production lots of the non replicating smallpox vaccine MVA: A randomised, double blind, placebo controlled phase III tr...
Overton, E. T., Lawrence, S. J., Wagner, E., Nopora, K., Rösch, S., Young, P., Schmidt, D., Kreusel, C., De Carli, S., Meyer, T. P., Weidenthaler, H., Samy, N., Chapli...> ;PloS one. 2018 Apr 14
Alterations in the oral microbiome in HIV-infected participants after ART administration are influenced by immune status.
Presti, R. M., Handley, S. A., Droit, L., Ghannoum, M. A., Jacobson, M. A., Shiboski, C. H., Webster-Cyriaque, J., Brown, T. T., Yin, M. T., Overton, E. T.> ;AIDS (London, England). 2018 Mar 30
Reply.
Elopre, L., Kudroff, K., Westfall, A. O., Overton, E. T., Mugavero, M. J.> ;Journal of acquired immune deficiency syndromes (1999). 2018 Jan 11
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Lectures

Screening in Emergency Department Identifies a Large Cohort of Unrecognized Chronic Hepatitis C Virus Infection among Baby Boomers
University of Alabama at Birmingham, Birmingham, AL - 5/15/2014

Press Mentions

Probiotic to Be Studied in People Living with HIVOctober 24, 2020 18:54
Antibody Supresses HIV in Infected IndividualsNovember 10, 2016 10:45
Probiotic to Be Studied in People Living with HIVFebruary 12, 2016 18:32

Hospital Affiliations

Birmingham Veterans Affairs Medical CenterBirmingham, Alabama
University of Alabama HospitalBirmingham, Alabama