EdwardDBallMD

Oncology • La Jolla, CA

Professor of Hematology & Oncology, UCSD

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Office
3855 Health Sciences Dr
La Jolla, CA 92093
Phone+1 858-822-6600

Fax+1 858-822-6844
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Education & Training

Dartmouth-Hitchcock/Mary Hitchcock Memorial HospitalFellowship, Hematology and Medical Oncology, 1982 - 1983
Case Western Reserve University/University Hospitals Cleveland Medical CenterFellowship, Hematology and Medical Oncology, 1979 - 1981
University of ConnecticutResidency, Internal Medicine, 1976 - 1979
Case Western Reserve University School of MedicineClass of 1976

Certifications & Licensure

NH State Medical License 1982 - Present
CA State Medical License 1998 - 2026
PA State Medical License 1991 - 1998
OH State Medical License 1979 - 1982
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013
Elected Member The American Society for Clinical Investigation, 1988
Whos Who in Medicine and Healthcare Marquis Whos Who
Super Doctor SuperDoctors.com
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Clinical Trials

Allogeneic Stem Cell Transplant After ATG, High-Dose Melphalan, and Fludarabine for Patients With Breast Cancer Start of enrollment: 2003 Jul 01
Terminated
Phase 2
Dosing Study of Ara-C/EL625/Idarubicin in Refractory and Relapsed AML Start of enrollment: 2004 Apr 01
Completed
Phase 2
Treatment for Acute Graft-Versus-Host Disease (BMT CTN 0302) Start of enrollment: 2005 Sep 01
Completed
Phase 2
Rituxan/BEAM vs Bexxar/BEAM in Autologous Hematopoietic Stem Cell Transplant for Non-Hodgkin's Lymphoma (BMTCTN0401) Start of enrollment: 2005 Dec 01
Completed
Phase 3
Combination 5-azacitidine and Gemtuzumab Ozogamicin Therapy for Treatment of Relapsed Acute Myeloid Leukemia (AML) Start of enrollment: 2005 Jul 01
Completed
Phase 1, Phase 2
Blood Stem Cell Transplant With Low Dose Chemotherapy for Relapsed Follicular Non-Hodgkin's Lymphoma (BMT CTN 0701) Start of enrollment: 2009 Apr 01
Completed
Phase 2
Stem Cell Related Donor Safety Study Start of enrollment: 2010 Jan 01
Completed
Chronic Graft-versus-Host Disease Treatment (BMT CTN 0801) Start of enrollment: 2010 Apr 01
Completed
Phase 2, Phase 3
Stem Cell Transplant With Lenalidomide Maintenance in Patients With Multiple Myeloma (BMT CTN 0702) Start of enrollment: 2010 May 01
Completed
Phase 3
Reduced Intensity Regimen vs Myeloablative Regimen for Myeloid Leukemia or Myelodysplastic Syndrome (BMT CTN 0901) Start of enrollment: 2011 Jun 01
Terminated
Phase 3
A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) Start of enrollment: 2011 Oct 01
Recruiting
Roles: Principal Investigator, Contact
Intravenous Administration of RGI-2001 in Patient Undergoing Allogenic Hematopoietic Stem Cell Transplantation (AHSCT) Start of enrollment: 2011 Sep 01
Completed
Phase 1, Phase 2
Safety Study of Unlicensed, Investigational Cord Blood Units Manufactured by the National Cord Blood Program (NCBP) for Unrelated Transplantation Start of enrollment: 2012 Feb 01
Recruiting
Phase 2
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Publications & Presentations

PubMed

4 citations
A global study for acute myeloid leukemia with RARG rearrangement.
Hong-Hu Zhu, Ya-Zhen Qin, Zhang-Lin Zhang, Yong-Jing Liu, Li-Jun Wen, M James You, Cheng Zhang, Esperanza Such, Hong Luo, Hong-Jian Yuan, Hong-Sheng Zhou, Hong-Xing Li...> ;Blood Advances. 2023 Jul 11
1 citations
Extracorporeal photopheresis for the treatment of chronic graft versus host disease.
Emin Kansu, David Ward, Amber P Sanchez, Robyn Cunard, Mutlu Hayran, Beril Huseyin, Majella Vaughan, Grace Ku, Peter Curtin, Carolyn Mulroney, Caitlin Costello, Januar...> ;Hematology. 2022 Dec 1
8 citations
Assessing CAR T-Cell Therapy Response Using Genome-Wide Sequencing of Cell-Free DNA in Patients With B-Cell Lymphomas.
Aaron M. Goodman, Kimberly A. Holden, Ah Reum Jeong, Lisa Kim, Kerry D. Fitzgerald, Eyad Almasri, Graham McLennan, Marcia Eisenberg, Amin Haghighat Jahromi, Carl K. Ho...> ;Transplantation and Cellular Therapy. 2021 Oct 13
11 citations
Alternative polyadenylation dysregulation contributes to the differentiation block of acute myeloid leukemia.
Amanda G Davis, Daniel T Johnson, Dinghai Zheng, Ruijia Wang, Nathan D. Jayne, Mengdan Liu, Jihae Shin, Luyang Wang, Samuel A Stoner, Jie-Hua Zhou, Edward D. Ball, Bin...> ;Blood. 2021 Sep 5
7 citations
MicroRNA let-7b downregulates AML1-ETO oncogene expression in t(8;21) AML by targeting its 3'UTR.
Daniel T Johnson, Amanda G Davis, Jie-Hua Zhou, Edward D. Ball, Dong-Er Zhang> ;Experimental Hematology & Oncology. 2021 Feb 2
5 citations
Predicting Responses to Checkpoint Inhibitors in Lymphoma: Are We Up to the Standards of Solid Tumors?
Ah-Reum Jeong, Edward D. Ball, Aaron M. Goodman> ;Clinical Medicine Insights. Oncology. 2020 Dec 28
7 citations
In vitro induction of neoantigen-specific T cells in myelodysplastic syndrome, a disease with low mutational burden
Valentina Ferrari, Alison Tarke, Hannah Fields, Luca Ferrari, Trevor Conley, Franco Ferrari, Zeynep Kosaloglu-Yalcin, Alessandro Sette, Bjoern Peters, Colin McCarthy, ...> ;Cytotherapy. 2021 Apr 1
8 citations
Gemtuzumab ozogamicin for the treatment of acute myeloid leukemia in adults.
Benjamin H. Goldenson, Aaron M. Goodman, Edward D. Ball> ;Expert Opinion on Biological Therapy. 2021 Jul 3
3 citations
Intensive Induction Therapy Compared With CHOP for Hepatosplenic T-cell Lymphoma.
Daniella Klebaner, Divya Koura, Dimitrios Tzachanis, Edward D. Ball, Steven M. Horwitz, Aaron M. Goodman> ;Clinical Lymphoma, Myeloma & Leukemia. 2020 Jul 1
48 citations
A multicenter phase 1 study of nivolumab for relapsed hematologic malignancies after allogeneic transplantation.
Matthew S. Davids, Haesook T. Kim, Caitlin Costello, Alex F. Herrera, Frederick L. Locke, Rodrigo O. Maegawa, Alexandra Savell, Michael Mazzeo, Adrienne Anderson, Alex...> ;Blood. 2020 Jun 11
66 citations
MHC-I genotype and tumor mutational burden predict response to immunotherapy.
Aaron M. Goodman, Andrea Castro, Rachel Marty Pyke, Ryosuke Okamura, Shumei Kato, Paul Riviere, Garrett M. Frampton, Ethan Sokol, Xinlian Zhang, Edward D. Ball, Hannah...> ;Genome Medicine. 2020 May 19
6 citations
Higher Risks of Toxicity and Incomplete Recovery in 13- to 17-Year-Old Females after Marrow Donation: RDSafe Peds Results.
Michael A. Pulsipher, Brent R. Logan, Deidre M. Kiefer, Pintip Chitphakdithai, Marcie L. Riches, J. Douglas Rizzo, Paolo Anderlini, Susan F. Leitman, James W. Varni, H...> ;Biology of Blood and Marrow Transplantation. 2019 May 1
10 citations
Effect of Aging and Predonation Comorbidities on the Related Peripheral Blood Stem Cell Donor Experience: Report from the Related Donor Safety Study
Michael A. Pulsipher, Brent R. Logan, Pintip Chitphakdithai, Deidre M. Kiefer, Marcie L. Riches, J. Douglas Rizzo, Paolo Anderlini, Susan F. Leitman, James W. Varni, H...> ;Biology of Blood and Marrow Transplantation. 2019 Apr 1
13 citations
Improved accuracy of clinical HLA genotyping by next-generation DNA sequencing affects unrelated donor search results for hematopoietic stem cell transplantation.
Elizabeth S. Allen, Bing Yang, Jodi Garrett, Edward D. Ball, Martin Maiers, Gerald P. Morris> ;Human Immunology. 2018 Dec 1
28 citations
A Phase I/II Trial of the Combination of Azacitidine and Gemtuzumab Ozogamicin for Treatment of Relapsed Acute Myeloid Leukemia.
Bruno C. Medeiros, Tiffany N. Tanaka, Larisa Balaian, Asad Bashey, Amy Guzdar, Hongying Li, Karen Messer, Edward D. Ball> ;Clinical Lymphoma, Myeloma & Leukemia. 2018 May 1
8 citations
Proinflammatory Dual Receptor T Cells in Chronic Graft-versus-Host Disease.
Amritha Balakrishnan, Nicholas J. Gloude, Roman Sasik, Edward D. Ball, Gerald P. Morris> ;Biology of Blood and Marrow Transplantation. 2017 Nov 1
43 citations
Increased Foxp3+Helios+ Regulatory T Cells and Decreased Acute Graft-versus-Host Disease after Allogeneic Bone Marrow Transplantation in Patients Receiving Sirolimus a...
Yi Bin Chen, Yvonne A. Efebera, Laura Johnston, Edward D. Ball, David Avigan, Lazaros J. Lekakis, Carlos Bachier, Paul J. Martin, Omar Duramad, Yasuyuki Ishii, Semi Ha...> ;Biology of Blood and Marrow Transplantation. 2017 Apr 1
What are the latest advancements in acute myeloid leukemia therapy
Aaron M. Goodman, Edward D. Ball> ;Future Oncology. 2017 Feb 27
1 citations
A 60-Year-Old Man With Progressive Anemia While Receiving Checkpoint Blockade Therapy for Relapsed Myelofibrosis.
Aaron M. Goodman, Megan Rust, Caitlin Costello, Edward D. Ball> ;Oncology. 2017 Feb 15
75 citations
CD98-Mediated Adhesive Signaling Enables the Establishment and Propagation of Acute Myelogenous Leukemia
Jeevisha Bajaj, Takaaki Konuma, Nikki K. Lytle, Hyog Young Kwon, Jailal N. G. Ablack, Joseph M. Cantor, David A. Rizzieri, Charles Chuah, Vivian G. Oehler, Elizabeth H...> ;Cancer Cell. 2016 Nov 14
84 citations
RNA Splicing Modulation Selectively Impairs Leukemia Stem Cell Maintenance in Secondary Human AML.
Leslie Crews, Larisa Balaian, Nathaniel Delos Santos, Heather Leu, Angela C. Court, Elisa Lazzari, Anil Sadarangani, Maria A. Zipeto, James J. La Clair, Reymundo Villa...> ;Cell Stem Cell. 2016 Nov 3
360 citations
Ipilimumab for Patients with Relapse after Allogeneic Transplantation
Matthew S. Davids, Haesook T. Kim, Pavan Bachireddy, Caitlin Costello, Rebecca Liguori, Alexandra Savell, Alexander Lukez, David Avigan, Yi-Bin Chen, Peter McSweeney, ...> ;The New England Journal of Medicine. 2016 Jul 13
7 citations
Novel FNDC3B and MECOM fusion and WT1 L378fs* 7 frameshift mutation in an acute myeloid leukaemia patient with cytomorphological and immunophenotypic features reminisc...
Huan-You Wang, Caitlin McMahon, Siraj M. Ali, Lauren Young, Somaye Yekezare, Jeffrey S. Ross, Edward D. Ball> ;British Journal of Haematology. 2016 Mar 1
5 citations
A scalable method for molecular network reconstruction identifies properties of targets and mutations in acute myeloid leukemia
Edison Ong, Anthony Szedlak, Yunyi Kang, Peyton Smith, Nicholas Smith, Madison McBride, Darren Finlay, Kristiina Vuori, James R. Mason, Edward D. Ball, Carlo Piermaroc...> ;Journal of Computational Biology. 2015 Apr 6
11 citations
Augmentation of autologous T cell reactivity with acute myeloid leukemia (AML) blasts by Toll-like receptor (TLR) agonists
Rui-kun Zhong, Hongying Li, Karen Messer, Thomas A. Lane, Jie-Hua Zhou, Edward D. Ball> ;Cancer Immunology, Immunotherapy. 2015 Mar 21
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Abstracts/Posters

Phase II Study of the Combination of Daratumumab, Ixazomib, Pomalidomide, and Dexamethasone As Salvage Therapy in Relapsed/Refractory Multiple Myeloma: Results of a Sa...
Edward D. Ball, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
Phase II Study of the Combination of Daratumumab, Ixazomib, Pomalidomide, and Dexamethasone As Salvage Therapy in Relapsed/Refractory Multiple Myeloma: Results of a Sa...
Edward D. Ball, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019

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