EdwardJCraneMD

PubMed

• 2 citations
  Sulfur-dependent microbial lifestyles: deceptively flexible roles for biochemically versatile enzymes.
  Edward J. Crane> ;Current Opinion in Chemical Biology. 2019 Apr 1
• 43 citations
  Circulating Tumor Cells in a Phase 3 Study of Docetaxel and Prednisone with or without Lenalidomide in Metastatic Castration-resistant Prostate Cancer
  Nicholas J. Vogelzang, Karim Fizazi, John M. Burke, Ronald de Wit, Joaquim Bellmunt, Thomas E. Hutson, Edward J. Crane, William R. Berry, Kevin Doner, John D. Hainswor...> ;European Urology. 2017 Feb 1
• 39 citations
  A Randomized, Open-Label Phase 2 Study of the CXCR4 Inhibitor LY2510924 in Combination with Sunitinib Versus Sunitinib Alone in Patients with Metastatic Renal Cell Car...
  John D. Hainsworth, James A. Reeves, Joseph R. Mace, Edward J. Crane, Oday Hamid, John R. Stille, Amy Flynt, Stephanie Roberson, John Polzer, Edward Arrowsmith> ;Targeted Oncology. 2016 May 7
• 5 citations
  Characterization of the mechanism of the NADH-dependent polysulfide reductase (Npsr) from Shewanella loihica PV-4: Formation of a productive NADH-enzyme complex and it...
  Kyu Hyun Lee, Scott Humbarger, Raj Bahnvadia, Matthew H. Sazinsky, Edward J. Crane> ;Biochimica Et Biophysica Acta. 2014 Sep 1
• 36 citations
  Pazopanib as second-line treatment after sunitinib or bevacizumab in patients with advanced renal cell carcinoma: a Sarah Cannon Oncology Research Consortium Phase II ...
  John D. Hainsworth, Mark S. Rubin, Edward Arrowsmith, James Khatcheressian, Edward J. Crane, Luis A. Franco> ;Clinical Genitourinary Cancer. 2013 Sep 1
• Nitrogen losses in anoxic marine sediments driven by Thioploca-anammox bacterial consortia.
  Prokopenko, M. G.,Hirst, M. B.,De Brabandere, L.,Lawrence, D. J.,Berelson, W. M.,Granger, J.,Chang, B. X.,Dawson, S.,Crane, E. J.,Chong, L.,Thamdrup, B.,Townsend-Small...> ;Nature. 2013 Aug 8
• 15 citations
  Structure and substrate specificity of the pyrococcal coenzyme A disulfide reductases/polysulfide reductases (CoADR/Psr): implications for S(0)-based respiration and a...
  Sanna E. Herwald, Albert Y. Liu, Brian E. Zhu, Kevin W. Sea, Karlo M. Lopez, Matthew H. Sazinsky, Edward J. Crane> ;Biochemistry. 2013 Apr 9
• 35 citations
  Electron transfer reactivity of type zero Pseudomonas aeruginosa azurin.
  Kyle M. Lancaster, Ole Farver, Scot Wherland, Edward J. Crane, John H. Richards, Israel Pecht, Harry B. Gray> ;Journal of the American Chemical Society. 2011 Apr 6
• 17 citations
  Characterization of an NADH-Dependent Persulfide Reductase from Shewanella loihica PV-4: Implications for the Mechanism of Sulfur Respiration via FAD-Dependent Enzymes .
  Megan D. Warner, Vinita Lukose, Kyu Hyun Lee, Karlo M. Lopez, Matthew H. Sazinsky, Edward J. Crane> ;Biochemistry. 2011 Jan 18
• 16 citations
  Cancer in nonagenarians: profile, treatments and outcomes.
  Martine Extermann, Edward J. Crane, David Boulware> ;Critical Reviews in Oncology/hematology. 2010 Aug 1
• 5 citations
  Single agent vinflunine in the salvage treatment of patients with castration-resistant prostate cancer: a phase II trial of the Sarah Cannon research consortium.
  John D. Hainsworth, A. A. Meluch, Cassie M. Lane, David R. Spigel, Howard A. Burris, Jitendra G. Gandhi, Edward J. Crane, Michael A. Stipanov, F. Anthony Greco> ;Cancer Investigation. 2010 Feb 16
• 1 citations
  WITHDRAWN: Cancer in nonagenarians: Profile, treatments and outcomes.
  Martine Extermann, Edward J. Crane, David Boulware> ;Critical Reviews in Oncology/hematology. 2009 Aug 31
• 31 citations
  Shewanella and Photobacterium spp. in Oysters and Seawater from the Delaware Bay
  Gary P. Richards, Michael A. Watson, Edward J. Crane, Iris G. Burt, David Bushek> ;Applied and Environmental Microbiology. 2008 Jun 1
• Vinflunine (VFL) as salvage chemotherapy in hormone-refractory prostate cancer (HRPC).
  Meluch AA, Spigel DR, Burris HA, Greco FA, Gandhi J, Crane E, Markus TM, Hainsworth JD> ;J. Clin. Oncol.. 2008-05-20
• Treating nonagenarians with cancer.
  Crane EJ, Extermann M> ;J. Clin. Oncol.. 2006-06-20
• 62 citations
  Borrelia burgdorferi bb0728 encodes a coenzyme A disulphide reductase whose function suggests a role in intracellular redox and the oxidative stress response.
  Julie A. Boylan, Charles S. Hummel, Stéphane L. Benoit, Jorge Garcia-Lara, Jennifer Treglown‐Downey, Edward J. Crane, Frank C. Gherardini> ;Molecular Microbiology. 2006 Jan 1
• 2 citations
  Adjuvant chemotherapy for non-small cell lung cancer
  Edward J. Crane, George R. Simon> ;Current Treatment Options in Oncology. 2006 Jan 1
• 26 citations
  Determination of coenzyme A levels in Pyrococcus furiosus and other Archaea: implications for a general role for coenzyme A in thermophiles
  Charles S. Hummel, Kyle M. Lancaster, Edward J. Crane> ;FEMS Microbiology Letters. 2005 Nov 1
• 22 citations
  Lenalidomide: an immunomodulatory drug.
  Edward Crane, Alan F. List> ;Future Oncology. 2005 Sep 22
• 30 citations
  Discovery and characterization of a Coenzyme A disulfide reductase from Pyrococcus horikoshii
  Dennis R. Harris, Donald E. Ward, Jeremy M. Feasel, Kyle M. Lancaster, Ryan D. Murphy, T. Conn Mallet, Edward J. Crane> ;The FEBS Journal. 2005 Mar 1
• 54 citations
  The NADH oxidase from Pyrococcus furiosus. Implications for the protection of anaerobic hyperthermophiles against oxidative stress.
  Donald E. Ward, Christopher J. Donnelly, Michael Eugene Mullendore, John van der Oost, Willem M. de Vos, Edward J. Crane> ;European Journal of Biochemistry. 2001 Nov 15
• 13 citations
  Analysis of the kinetic and redox properties of the NADH peroxidase R303M mutant: correlation with the crystal structure.
  Edward J. Crane, Joanne I. Yeh, James Luba, Al Claiborne> ;Biochemistry. 2000 Aug 29
• 391 citations
  Protein-sulfenic acids: diverse roles for an unlikely player in enzyme catalysis and redox regulation.
  Al Claiborne, Joanne I. Yeh, Mallett Tc, Luba J, Crane Ej rd, Charrier, Derek Parsonage> ;Biochemistry. 1999 Nov 2
• 24 citations
  13C NMR Analysis of the Cysteine-Sulfenic Acid Redox Center of Enterococcal NADH Peroxidase†
  Edward J. Crane, Jacques Vervoort, Al Claiborne> ;Biochemistry. 1997 Jul 15
• 15 citations
  The Active-Site Histidine-10 of Enterococcal NADH Peroxidase Is Not Essential for Catalytic Activity†
  Edward J. Crane, Derek Parsonage, Al Claiborne> ;Biochemistry. 1996 Feb 20
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