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740 Rose StLexington, KY 40536
Phone+1 859-323-5661
Fax+1 859-257-5477
Dr. Kasarskis is on Doximity
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Education & Training
University of Virginia Medical CenterResidency, Neurology, 1976 - 1979
University of Wisconsin Hospitals and ClinicsResidency, Internal Medicine, 1974 - 1976
University of WisconsinPhD, Biochemistry, 1968 - 1975
University of Wisconsin School of Medicine & Public HealthClass of 1974
Certifications & Licensure
KY State Medical License 1980 - 2026
WI State Medical License 1975 - 2005
LA State Medical License 1979 - 1987
American Board of Psychiatry and Neurology Neurology
Clinical Trials
- Early Treatment of Amyotrophic Lateral Sclerosis (ALS) With Nutrition and Non-Invasive Positive Pressure Ventilation Start of enrollment: 2004 Aug 01
- Longitudinal Study of Outcomes Measures in ALS Trials Start of enrollment: 2013 Jul 01
- Treatment of FUS-Related ALS With Betamethasone - The TRANSLATE Study Start of enrollment: 2017 Aug 21
Publications & Presentations
PubMed
- Primary Lateral Sclerosis Natural History Study: Primary Lateral Sclerosis Functional Rating Scale and Other Outcomes Assessment.Ikjae Lee, Grace Jang, Ying Kuen Ken Cheung, Alexander V Sherman, Wendy S Johnston
Annals of Neurology. 2025-09-29 - 4 citationsVerdiperstat in Amyotrophic Lateral Sclerosis: Results From the Randomized HEALEY ALS Platform Trial., Jinsy Andrews, Sabrina Paganoni, Eric A Macklin, Lori B Chibnik
JAMA Neurology. 2025-04-01 - Interaction between riluzole treatment and dietary glycemic index in the disease progression of amyotrophic lateral sclerosis.Ikjae Lee, Hiroshi Mitsumoto, Seonjoo Lee, Edward Kasarskis, Michael Rosenbaum
Annals of Clinical and Translational Neurology. 2025-03-01
Journal Articles
- Trial of Sodium Phenylbutyrate–Taurursodiol for Amyotrophic Lateral SclerosisSabrina Paganoni, Michael A Elliott, Samuel Maiser, Margaret A Owegi, Stephen A Goutman, Carlayne E Jackson, Jeffrey D Rothstein, Edward J Kasarskis, Liberty Jenkins, ..., The New England Journal of Medicine
- ALS Mutations of FUS Suppress Protein Translation and Disrupt the Regulation of Nonsense-Mediated DecayEdward Kasarskis, MD, Proceedings of the National Academy of Sciences
Press Mentions
UK Pathology Resident Exhibits Photography Collection to Honor Friend with ALSNovember 21st, 2022
ALS-Causative Mutations in FUS/TLS Confer Gain- and Loss-of-Function by Altered Association with SMN and U1-snRNPJanuary 27th, 2020
49ers’ Dwight Clark Tragedy: Can Football Cause ALS?March 20th, 2017- Join now to see all
Grant Support
- Early Treatment Of ALS With Nutrition And NippvNational Center For Research Resources2005–2007
- Early Treatment Of ALS With Nutrition And NippvNational Institute Of Neurological Disorders And Stroke2004–2007
- Phase III Trial Of Minocycline In Amyotrophic Lateral SclerosisNational Center For Research Resources2004–2007
- Assessment Of Caloric Needs In Amyotrophic Lateral Sclerosis (ALS)National Center For Research Resources2004–2005
- Celebrex In ALSNational Center For Research Resources2004
- Upper And Lower Anthropometry To Assess The Progression Of Weakness In ALSNational Center For Research Resources1996–1997
- Laser Microprobe Analysis Of Neuronal MercuryNational Institute Of Neurological Disorders And Stroke1988–1990
- Zinc Nutrition And Alcohol--Effect On Fetal BrainNational Institute On Alcohol Abuse And Alcoholism1985–1987
- Role Of Zinc At The Hippocampal Mossy Fiber SynapseNational Institute Of Neurological Disorders And Stroke1985–1987
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