EleanorBarrValenziMD

PubMed

• 1 citations
  Increased expression of CXCL6 in secretory cells drives fibroblast collagen synthesis and is associated with increased mortality in idiopathic pulmonary fibrosis.
  Bahudhanapati, H., Tan, J., Apel, R., Seeliger, B., Schupp, J., Li, X., Sullivan, D., Sembrat, J., Rojas, M., Tabib, T., Valenzi, E., Lafyatis, R., Mitash, N., Hernand...> ;The European Respiratory Journal. 2024 Jan 1
• LEF1 isoforms regulate cellular senescence and aging.
  Minxue Jia, Khaled Sayed, Maria G Kapetanaki, William Dion, Lorena Rosas, Saad Irfan, Eleanor Valenzi, Ana L Mora, Robert A Lafyatis, Mauricio Rojas, Bokai Zhu, Panayi...> ;Aging Cell. 2023 Dec 1
• LEF1 isoforms regulate cellular senescence and aging.
  Minxue Jia, Khaled Sayed, Maria G Kapetanaki, William Dion, Lorena Rosas, Saad Irfan, Eleanor Valenzi, Ana L Mora, Robert A Lafyatis, Mauricio Rojas, Bokai Zhu, Panayi...> ;Biorxiv. 2023 Jul 21
• Impact of enzymatic digestion on single cell suspension yield from peripheral human lung tissue.
  Anna Bondonese, Andrew Craig, Li Fan, Eleanor Valenzi, William Bain, Robert Lafyatis, John Sembrat, Kong Chen, Mark E Snyder> ;Cytometry. Part A. 2023 Oct 1
• 1 citations
  Usual interstitial pneumonia is the predominant histopathology in patients with systemic sclerosis receiving a lung transplant.
  Eleanor Valenzi, Brittany Cody, Robert Lafyatis> ;Clinical and Experimental Rheumatology. 2023 Aug 1
• 3 citations
  Increased CD8+ tissue resident memory T cells, regulatory T cells and activated natural killer cells in systemic sclerosis lungs.
  Cristina M Padilla, Eleanor Valenzi, Tracy Tabib, Banafsheh Nazari, John Sembrat, Mauricio Rojas, Patrizia Fuschiotti, Robert Lafyatis> ;Rheumatology. 2024 Mar 1
• 13 citations
  PCSK6 and Survival in Idiopathic Pulmonary Fibrosis.
  Kaminski, N., Justin M Oldham, Richard J Allen, Jose M Lorenzo-Salazar, Philip L Molyneaux, Shwu-Fan Ma, Chitra Joseph, John S Kim, Beatriz Guillen-Guio, Tamara Hernán...> ;American Journal of Respiratory and Critical Care Medicine. 2023 Jun 1
• 3 citations
  Single-nucleus chromatin accessibility identifies a critical role for TWIST1 in idiopathic pulmonary fibrosis myofibroblast activity.
  Eleanor Valenzi, Harinath Bahudhanapati, Jiangning Tan, Tracy Tabib, Daniel I Sullivan, Mehdi Nouraie, John Sembrat, Li Fan, Kong Chen, Silvia Liu, Mauricio Rojas, Aud...> ;The European Respiratory Journal. 2023 Jul 1
• 8 citations
  Biomarkers of haemodynamic severity of systemic sclerosis-associated pulmonary arterial hypertension by serum proteome analysis.
  Sébastien Sanges, Lisa Rice, Ly Tu, Eleanor Valenzi, Jean-Luc Cracowski, David Montani, Julio C Mantero, Camille Ternynck, Guillemette Marot, Andreea M Bujor, Eric Hac...> ;Annals of the Rheumatic Diseases. 2023 Mar 1
• 8 citations
  Assessment of disease outcome measures in systemic sclerosis.
  Robert Lafyatis, Eleanor Valenzi> ;Nature Reviews. Rheumatology. 2022 Sep 1
• 1 citations
  Fibronectin-EDA accumulates via reduced ubiquitination downstream of Toll-like receptor 9 activation in SSc-ILD fibroblasts.
  Ferhan Tuncer, Melissa Bulik, John Villandre, Travis Lear, Yanwen Chen, Beyza Tuncer, Daniel J Kass, Eleanor Valenzi, Christina Morse, John Sembrat 2nd, Robert Lafyati...> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2022 Oct 1
• 9 citations
  Epigenetic Regulation of Profibrotic Macrophages in Systemic Sclerosis-Associated Interstitial Lung Disease.
  Anna Papazoglou, Mengqi Huang, Melissa Bulik, Annika Lafyatis, Tracy Tabib, Christina Morse, John Sembrat, Mauricio Rojas, Eleanor Valenzi, Robert Lafyatis> ;Arthritis & Rheumatology. 2022 Dec 1
• 5 citations
  β-Agonist exposure preferentially impacts lung macrophage cyclic AMP-related gene expression in asthma and asthma COPD overlap syndrome
  Kaveh Moghbeli, Eleanor Valenzi, Rachel Naramore, John Sembrat, Kong Chen, Mauricio Rojas, Sally E. Wenzel, Robert Lafyatis, Brian D. Modena, Nathaniel M. Weathington> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2021 Sep 8
• 41 citations
  Disparate Interferon Signaling and Shared Aberrant Basaloid Cells in Single-Cell Profiling of Idiopathic Pulmonary Fibrosis and Systemic Sclerosis-Associated Interstit...
  Eleanor Valenzi, Tracy Tabib, Anna Papazoglou, John Sembrat, Humberto E. Trejo Bittar, Mauricio Rojas, Robert Lafyatis> ;Frontiers in Immunology. 2021 Mar 30
• 8 citations
  Topographic heterogeneity of lung microbiota in end-stage idiopathic pulmonary fibrosis: The Microbiome in Lung Explants-2 (MiLEs-2) study
  Eleanor Valenzi, Haopu Yang, John Sembrat, L. Yang, Spencer A. Winters, Rachel Nettles, Daniel J. Kass, Shulin Qin, X. Wang, Michael M. Myerburg, Barbara Methé, Adam F...> ;Thorax. 2021 Mar 1
• 11 citations
  Mitochondria, Aging, and Cellular Senescence: Implications for Scleroderma
  Marta Bueno, Anna Papazoglou, Eleanor Valenzi, Mauricio Rojas, Robert Lafyatis, Ana L. Mora> ;Current Rheumatology Reports. 2020 Jun 19
• Kelch-like protein 42 is a profibrotic ubiquitin E3 ligase involved in systemic sclerosis.
  Travis B Lear, Karina C Lockwood, Mads Larsen, Ferhan Tuncer, Jason R Kennerdell, Christina Morse, Eleanor Valenzi, Tracy Tabib, Michael J Jurczak, Daniel J Kass, John...> ;The Journal of Biological Chemistry. 2020 Mar 27
• 45 citations
  Transcriptional profiling of lung cell populations in idiopathic pulmonary arterial hypertension.
  Didem Saygin, Tracy Tabib, Humberto E. Trejo Bittar, Eleanor Valenzi, John Sembrat, Stephen Y. Chan, Mauricio Rojas, Robert Lafyatis> ;Pulmonary Circulation. 2020 Feb 28
• 9 citations
  KIAA0317 regulates pulmonary inflammation through SOCS2 degradation
  Travis Lear, Alison C. McKelvey, John Evankovich, Shristi Rajbhandari, Tiffany A. Coon, Sarah R. Dunn, James D. Londino, Bryan J. McVerry, Yingze Zhang, Eleanor Valenz...> ;JCI Insight. 2019 Oct 3
• 148 citations
  Single-cell Analysis Reveals Fibroblast Heterogeneity and Myofibroblasts in Systemic Sclerosis-Associated Interstitial Lung Disease
  Eleanor Valenzi, Melissa Bulik, Tracy Tabib, Christina Morse, John Sembrat, Humberto E. Trejo Bittar, Mauricio Rojas, Robert Lafyatis> ;Annals of the Rheumatic Diseases. 2019 Oct 1
• 294 citations
  Proliferating SPP1/MERTK-expressing Macrophages in Idiopathic Pulmonary Fibrosis
  Christina Morse, Tracy Tabib, John Sembrat, Kristina L. Buschur, Humberto E. Trejo Bittar, Eleanor Valenzi, Yale Jiang, Daniel J. Kass, Kevin F. Gibson, Wei Chen, Ana ...> ;The European Respiratory Journal. 2019 Aug 1
• 1 citations
  Diagnosis from Afar: Is Remote Multidisciplinary Discussion Appropriate for Interstitial Lung Disease Care?
  Eleanor Valenzi, Daniel J. Kass> ;Annals of the American Thoracic Society. 2019 Apr 1
• 22 citations
  Interstitial Pneumonia With Autoimmune Features: Value of Histopathology
  Ayodeji Adegunsoye, Justin M. Oldham, Eleanor Valenzi, Cathryn Lee, Leah J. Witt, Lena Chen, Steven M. Montner, Jonathan H. Chung, Imre Noth, Rekha Vij, Mary E. Strek,...> ;Archives of Pathology & Laboratory Medicine. 2017 May 3
• 65 citations
  Azathioprine response in patients with fibrotic connective tissue disease-associated interstitial lung disease
  Justin M. Oldham, Cathryn Lee, Eleanor Valenzi, Leah J. Witt, Ayodeji Adegunsoye, Scully Hsu, Lena Chen, Steven M. Montner, Jonathan H. Chung, Imre Noth, Rekha Vij, Ma...> ;Respiratory Medicine. 2016 Dec 1
• 180 citations
  Characterisation of patients with interstitial pneumonia with autoimmune features.
  Justin M. Oldham, Ayodeji Adegunsoye, Eleanor Valenzi, Cathryn Lee, Leah J. Witt, Lena Chen, Aliya N. Husain, Steven M. Montner, Jonathan H. Chung, Vincent Cottin, Ary...> ;The European Respiratory Journal. 2016 Apr 21
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