ElieATraerMD

PubMed

• Mapping the proteogenomic landscape enables prediction of drug response in acute myeloid leukemia.
  James C Pino, Camilo Posso, Sunil K Joshi, Michael Nestor, Jamie Moon, Joshua R Hansen, Chelsea Hutchinson-Bunch, Marina A Gritsenko, Karl K Weitz, Kevin Watanabe-Smit...> ;Cell Reports. Medicine. 2024 Jan 16
• 1 citations
  Phase Ib study of sabatolimab (MBG453), a novel immunotherapy targeting TIM-3 antibody, in combination with decitabine or azacitidine in high- or very high-risk myelod...
  Andrew M Brunner, Jordi Esteve, Kimmo Porkka, Steve Knapper, Elie Traer, Sebastian Scholl, Guillermo Garcia-Manero, Norbert Vey, Martin Wermke, Jeroen J W M Janssen, R...> ;American Journal of Hematology. 2024 Feb 1
• The FLT3mutation causes clinical AML resistance to gilteritinib and triggers TKI sensitivity switch to quizartinib.
  Sunil K Joshi, Janét Pittsenbarger, Vanessa E Kennedy, Cheryl A C Peretz, Alexander E Perl, Catherine C Smith, Jeffrey W Tyner, Brian J Druker, Elie Traer> ;American Journal of Hematology. 2023 Dec 1
• 2 citations
  Building on Foundations: Venetoclax-Based Combinations in the Treatment of Acute Myeloid Leukemia.
  Emmanuella Oyogoa, Elie Traer, Jeffrey Tyner, Curtis Lachowiez> ;Cancers. 2023 Jul 12
• 1 citations
  Outcomes with molecularly targeted agents as salvage therapy following frontline venetoclax + hypomethylating agent in adults with acute myeloid leukemia: A multicente...
  Vishesh Khanna, Tali Azenkot, Selina Qiuying Liu, Jason Gilbert, Edna Cheung, Kimberly Lau, Daniel A Pollyea, Elie Traer, Brian A Jonas, Tian Y Zhang, Gabriel N Mannis> ;Leukemia Research. 2023 Aug 1
• 63 citations
  Integrative analysis of drug response and clinical outcome in acute myeloid leukemia.
  Daniel Bottomly, Nicola Long, Anna Reister Schultz, Stephen E Kurtz, Cristina E Tognon, Kara Johnson, Melissa Abel, Anupriya Agarwal, Sammantha Avaylon, Erik Benton, A...> ;Cancer Cell. 2022 Aug 8
• 9 citations
  Proteomic and phosphoproteomic measurements enhance ability to predict ex vivo drug response in AML.
  Gosline, S., Tognon, C., Nestor, M., Joshi, S., Modak, R., Damnernsawad, A., Posso, C., Moon, J., Hansen, J., Hutchinson-Bunch, C., Pino, J., Gritsenko, M., Weitz, K.,...> ;Clinical Proteomics. 2022 Jul 27
• 48 citations
  The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance
  Sunil K. Joshi, Tamilla Nechiporuk, Daniel Bottomly, Paul D. Piehowski, Julie A. Reisz, Janét Pittsenbarger, Andy Kaempf, Sara J. C. Gosline, Yi-Ting Wang, Joshua R. H...> ;Cancer Cell. 2021 Jul 12
• 27 citations
  IDH Inhibitors in AML—Promise and Pitfalls
  Hannah Stowe McMurry, Luke B Fletcher, Elie Traer> ;Current Hematologic Malignancy Reports. 2021 Apr 30
• 11 citations
  Engrafted Donor-Derived Clonal Hematopoiesis after Allogenic Hematopoietic Cell Transplantation is Associated with Chronic Graft-versus-Host Disease Requiring Immunosu...
  Laura F. Newell, Todd Williams, James K. Liu, Yun Yu, Yiyi Chen, Georgeann C. Booth, R. Knight, Kelli R. Goslee, Rachel J. Cook, Jessica Leonard, Gabrielle Meyers, Eli...> ;Transplantation and Cellular Therapy. 2021 Aug 1
• 267 citations
  Proteogenomic and metabolomic characterization of human glioblastoma
  Liang-Bo Wang, Alla Karpova, Marina A. Gritsenko, Jennifer E. Kyle, Song Cao, Yize Li, Dmitry Rykunov, Antonio Colaprico, Joseph H. Rothstein, Runyu Hong, Vasileios St...> ;Cancer Cell. 2021 Apr 12
• 10 citations
  A noncanonical FLT3 gatekeeper mutation disrupts gilteritinib binding and confers resistance.
  Sunil K. Joshi, Setareh Sharzehi, Janét Pittsenbarger, Daniel Bottomly, Cristina E. Tognon, Shannon K. McWeeney, Brian J. Druker, Elie Traer> ;American Journal of Hematology. 2021 Mar 29
• 162 citations
  Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma
  Chen Huang, Lijun Chen, Sara R. Savage, Rodrigo Vargas Eguez, Yongchao Dou, Yize Li, Felipe da Veiga Leprevost, Eric J. Jaehnig, Jonathan T. Lei, Bo Wen, Michael Schna...> ;Cancer Cell. 2021 Mar 8
• 84 citations
  Precision medicine treatment in acute myeloid leukemia using prospective genomic profiling: feasibility and preliminary efficacy of the Beat AML Master Trial.
  Amy Burd, Ross L. Levine, Amy S. Ruppert, Alice S. Mims, Uma Borate, Eytan M. Stein, Prapti A. Patel, Maria R. Baer, Wendy Stock, Michael W. Deininger, William Blum, G...> ;Nature Medicine. 2020 Oct 26
• 22 citations
  Discovery and characterization of targetable NTRK point mutations in hematologic neoplasms
  Sunil K. Joshi, Kristin Qian, William H. Bisson, Kevin Watanabe-Smith, Ariane Huang, Daniel Bottomly, Elie Traer, Jeffrey W. Tyner, Shannon K. McWeeney, Monika A. Dava...> ;Blood. 2020 Jun 11
• 9 citations
  ERBB2/HER2 mutations are transforming and therapeutically targetable in leukemia.
  Sunil K. Joshi, Jamie M. Keck, Christopher A. Eide, Daniel Bottomly, Elie Traer, Jeffrey W. Tyner, Shannon K. McWeeney, Cristina E. Tognon, Brian J. Druker> ;Leukemia. 2020 May 4
• 237 citations
  Proteogenomic Characterization of Endometrial Carcinoma.
  Yongchao Dou, Emily Kawaler, Daniel Cui Zhou, Marina A. Gritsenko, Chen Huang, Lili Blumenberg, Alla Karpova, Vladislav A. Petyuk, Sara R. Savage, Shankha Satpathy, We...> ;Cell. 2020 Feb 20
• 19 citations
  Profile of Quizartinib for the Treatment of Adult Patients with Relapsed/Refractory FLT3-ITD-Positive Acute Myeloid Leukemia: Evidence to Date.
  Luke B Fletcher, Sunil K. Joshi, Elie Traer> ;Cancer Management and Research. 2020 Jan 8
• 1 citations
  Reducing acetyl-CoA enhances BET inhibition
  Elie Traer> ;Blood. 2019 Dec 12
• 27 citations
  The combination of NPM1, DNMT3A, and IDH1/2 mutations leads to inferior overall survival in AML.
  Jennifer Dunlap, Jessica Leonard, Mara Rosenberg, Rachel J. Cook, Richard D. Press, Guang Fan, Philipp W. Raess, Brian J. Druker, Elie Traer> ;American Journal of Hematology. 2019 Aug 1
• 2 citations
  Erratum: Correction: FGF2-FGFR1 signaling regulates release of leukemia-protective exosomes from bone marrow stromal cells (eLife (2019) 8 PII: e47174)
  Nathalie Javidi-Sharifi, Jacqueline Martinez, Isabel English, Sunil K. Joshi, Renata Scopim-Ribeiro, Shelton K. Viola, David K. Edwards, Anupriya Agarwal, Claudia S. L...> ;Elife. 2019 Mar 29
• 5 citations
  Allogeneic transplantation outcomes amongst a contemporary cohort of high-risk myelodysplastic syndrome and acute myeloid leukemia patients aged ≥70 years.
  Curtis Lachowiez, Rachel J. Cook, Brandon Hayes-Lattin, Richard T. Maziarz, Uma Borate, Elie Traer, Jessica Leonard, Laura F. Newell, Kim Hien T. Dao, Gabrielle Meyers> ;Hematology/oncology and Stem Cell Therapy. 2019 Jun 1
• 44 citations
  Pracinostat plus azacitidine in older patients with newly diagnosed acute myeloid leukemia: results of a phase 2 study
  Guillermo Garcia-Manero, Yasmin Abaza, Koichi Takahashi, Bruno C. Medeiros, Martha Arellano, Samer K. Khaled, Mrinal M. Patnaik, Olatoyosi Odenike, Hamid Sayar, Mohan ...> ;Blood Advances. 2019 Feb 26
• 25 citations
  FGF2-FGFR1 signaling regulates release of Leukemia-Protective exosomes from bone marrow stromal cells.
  Nathalie Javidi-Sharifi, Jacqueline Martinez, Isabel English, Sunil K Joshi, Renata Scopim-Ribeiro, Shelton K Viola, David K Edwards 5th, Anupriya Agarwal, Claudia Lop...> ;Elife. 2019 Feb 5
• 702 citations
  Functional genomic landscape of acute myeloid leukaemia
  Jeffrey W. Tyner, Cristina E. Tognon, Daniel Bottomly, Beth Wilmot, Stephen E. Kurtz, Samantha L. Savage, Nicola Long, Anna Reister Schultz, Elie Traer, Melissa L. Abe...> ;Nature. 2018 Oct 17
• Join now to see all