ElizabethAnnStewartMD

PubMed

• DNAJB1-PRKACA fusion neoantigens elicit rare endogenous T cell responses that potentiate cell therapy for fibrolamellar carcinoma.
  Allison M Kirk, Jeremy Chase Crawford, Ching-Heng Chou, Cliff Guy, Kirti Pandey, Tanya Kozlik, Ravi K Shah, Shanzou Chung, Phuong Nguyen, Xiaoyu Zhang, Jin Wang, Matth...> ;Cell Reports. Medicine. 2024 Mar 19
• A spatial cell atlas of neuroblastoma reveals developmental, epigenetic and spatial axis of tumor heterogeneity.
  Patel, A., Ashenberg, O., Collins, N., Segerstolpe, Å., Jiang, S., Slyper, M., Huang, X., Caraccio, C., Jin, H., Sheppard, H., Xu, K., Chang, T., Orr, B., Shirinifard,...> ;Biorxiv. 2024 Jan 16
• 14 citations
  The myogenesis program drives clonal selection and drug resistance in rhabdomyosarcoma.
  Anand G Patel, Xiang Chen, Xin Huang, Michael R Clay, Natalia Komorova, Matthew J Krasin, Alberto Pappo, Heather Tillman, Brent A Orr, Justina McEvoy, Brittney Gordon,...> ;Developmental Cell. 2022 May 23
• 3 citations
  Antigen cross-presentation in young tumor-bearing hosts promotes CD8T cell terminal differentiation.
  Ardiana Moustaki, Jeremy Chase Crawford, Shanta Alli, Yiping Fan, Shannon Boi, Anthony E Zamora, Natalie M N McDonald, Gang Wu, Joy Nakitandwe, Scott Newman, Scott Foy...> ;Science Immunology. 2022 Feb 4
• 37 citations
  Improved Outcome in Children With Newly Diagnosed High-Risk Neuroblastoma Treated With Chemoimmunotherapy: Updated Results of a Phase II Study Using hu14.18K322A.
  Wayne L Furman, Beth McCarville, Barry L Shulkin, Andrew Davidoff, Matthew Krasin, Chia-Wei Hsu, Haitao Pan, Jianrong Wu, Rachel Brennan, Michael W Bishop, Sara Helmig...> ;Journal of Clinical Oncology. 2022 Feb 1
• 7 citations
  Methylation profiling reveals novel molecular classes of rhabdomyosarcoma.
  Michael R Clay, Anand G. Patel, Quynh T. Tran, Dale Hedges, Ti-Cheng Chang, Elizabeth Stewart, Greg W. Charville, Cynthia Cline, Michael A. Dyer, Brent A. Orr> ;Scientific Reports. 2021 Nov 15
• 31 citations
  The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma.
  Min Pan, William C. Wright, Richard H. Chapple, Asif Zubair, Manbir Sandhu, Jake E. Batchelder, Brandt C. Huddle, Jonathan Low, Kaley Blankenship, Yingzhe Wang, Brittn...> ;Nature Communications. 2021 Nov 9
• 4 citations
  SLFN11 is widely expressed in pediatric sarcoma and induces variable sensitization to replicative stress caused by DNA damaging agents
  Jessica Gartrell, Marcia Mellado-Largarde, Michael R. Clay, Armita Bahrami, Natasha Sahr, April Sykes, Kaley Blankenship, Lauren Hoffmann, Jia Xie, Hyekyung P. Cho, Na...> ;Molecular Cancer Therapeutics. 2021 Aug 19
• 6 citations
  Charting a path for prioritization of novel agents for clinical trials in osteosarcoma: A report from the Children's Oncology Group New Agents for Osteosarcoma Task Fo...
  Sarah B. Whittle, Katharine Offer, Ryan D. Roberts, Amy K. LeBlanc, Cheryl A. London, Robbie G. Majzner, Alex Yee-Chen Huang, Peter J. Houghton, E. Alejandro Sweet Cor...> ;Pediatric Blood & Cancer. 2021 Jun 16
• 9 citations
  Prioritization of Novel Agents for Patients with Rhabdomyosarcoma: A Report from the Children’s Oncology Group (COG) New Agents for Rhabdomyosarcoma Task Force
  Holly L Pacenta, Wendy Allen-Rhoades, David M. Langenau, Peter J. Houghton, Charles Keller, Christine M. Heske, Michael D. Deel, Corinne M. Linardic, Jack F. Shern, El...> ;Journal of Clinical Medicine. 2021 Apr 1
• 14 citations
  Next-generation humanized patient-derived xenograft mouse model for pre-clinical antibody studies in neuroblastoma
  Rosa Nguyen, Anand G. Patel, Lyra Griffiths, Jason Dapper, Elizabeth Stewart, Jim Houston, Melissa Johnson, Walter J. Akers, Wayne L. Furman, Michael A. Dyer> ;Cancer Immunology, Immunotherapy. 2021 Mar 1
• Orthotopic Implants in Mice.
  Elizabeth Stewart> ;Methods in Molecular Biology. 2021 Jan 1
• 34 citations
  A phase I trial of talazoparib and irinotecan with and without temozolomide in children and young adults with recurrent or refractory solid malignancies
  Sara M. Federico, Alberto S. Pappo, Natasha Sahr, April Sykes, Olivia Campagne, Clinton F. Stewart, Michael R. Clay, Armita Bahrami, Mary Beth McCarville, Sue C. Kaste...> ;European Journal of Cancer. 2020 Sep 1
• 11 citations
  Rhabdoid Tumors Are Sensitive to the Protein-Translation Inhibitor Homoharringtonine
  , , , , , , , , , , , , , , , , , , , , , , , , > ;Clinical Cancer Research. 2020 Jul 6
• 59 citations
  MYCN amplification and ATRX mutations are incompatible in neuroblastoma.
  Maged Zeineldin, Sara M. Federico, Xiang Chen, Yiping Fan, Beisi Xu, Elizabeth Stewart, Xin Zhou, Jongrye Jeon, Lyra Griffiths, Rosa Nguyen, Jackie L. Norrie, John Eas...> ;Nature Communications. 2020 Feb 14
• 45 citations
  ATRX In-Frame Fusion Neuroblastoma Is Sensitive to EZH2 Inhibition via Modulation of Neuronal Gene Signatures.
  Zulekha A. Qadeer, David Valle-Garcia, Dan Hasson, Zhen Sun, April Cook, Christie B. Nguyen, Aroa Soriano, Anqi Ma, Lyra Griffiths, Maged Zeineldin, Dan Filipescu, Luz...> ;Cancer Cell. 2019 Nov 11
• 47 citations
  A Phase II Trial of Hu14.18K322A in Combination with Induction Chemotherapy in Children with Newly Diagnosed High-Risk Neuroblastoma.
  Wayne L. Furman, Sara M. Federico, Mary Beth McCarville, Barry L. Shulkin, Andrew M. Davidoff, Matthew J. Krasin, Natasha Sahr, April Sykes, Jianrong Wu, Rachel C. Bre...> ;Clinical Cancer Research. 2019 Nov 1
• 25 citations
  Positron Emission Tomography Detects In Vivo Expression of Disialoganglioside GD2 in Mouse Models of Primary and Metastatic Osteosarcoma
  Elizabeth R. Butch, Paul E. Mead, Victor Amador Diaz, Heather Tillman, Elizabeth Stewart, Jitendra K. Mishra, Jieun Kim, Armita Bahrami, Jason L. J. Dearling, Alan B. ...> ;Cancer Research. 2019 Jun 15
• 49 citations
  Emerging novel agents for patients with advanced Ewing sarcoma: a report from the Children's Oncology Group (COG) New Agents for Ewing Sarcoma Task Force.
  Kelly M. Bailey, Carrye R. Cost, Ian J. Davis, Julia Glade-Bender, Patrick J. Grohar, Peter J. Houghton, Michael S. Isakoff, Elizabeth Stewart, Nadia N. Laack, Jason T...> ;F1000research. 2019 Apr 15
• 23 citations
  Combinatorial screening using orthotopic patient derived xenograft-expanded early phase cultures of osteosarcoma identify novel therapeutic drug combinations.
  Amos Hong Pheng Loh, Elizabeth Stewart, Cori Bradley, Xiang Chen, Vinay M. Daryani, Clinton F. Stewart, Christopher Calabrese, Amy J. Funk, Greg Miller, Asa Karlstrom,...> ;Cancer Letters. 2019 Feb 1
• 92 citations
  Identification of Therapeutic Targets in Rhabdomyosarcoma Through Integrated Genomic, Epigenomic, and Proteomic Analyses
  Elizabeth Stewart, Justina McEvoy, Hong Wang, Xiang Chen, Victoria Honnell, Monica Ocarz, Brittney Gordon, Jason Dapper, Kaley Blankenship, Yanling Yang, Yuxin Li, Tim...> ;Cancer Cell. 2018 Sep 10
• 181 citations
  Orthotopic patient-derived xenografts of paediatric solid tumours
  Elizabeth Stewart, Sara M. Federico, Xiang Chen, Anang A. Shelat, Cori Bradley, Brittney Gordon, Asa Karlstrom, Nathaniel R. Twarog, Michael R. Clay, Armita Bahrami, B...> ;Nature. 2017 Aug 30
• 55 citations
  The Childhood Solid Tumor Network: A new resource for the developmental biology and oncology research communities
  Elizabeth Stewart, Sara M. Federico, Asa Karlstrom, Anang A. Shelat, Andras Sablauer, Alberto S. Pappo, Michael A. Dyer> ;Developmental Biology. 2016 Mar 15
• 34 citations
  The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease.
  Heinrich Kovar, James F. Amatruda, Erika Brunet, Stefan Burdach, Florencia Cidre-Aranaz, Enrique de Alava, Uta Dirksen, Wietske van der Ent, Patrick J. Grohar, Thomas ...> ;Oncotarget. 2016 Jan 18
• 215 citations
  Targeting Oxidative Stress in Embryonal Rhabdomyosarcoma
  Xiang Chen, Elizabeth Stewart, Anang A. Shelat, Chunxu Qu, Armita Bahrami, Mark E. Hatley, Gang Wu, Cori Bradley, Justina McEvoy, Alberto S. Pappo, Sheri L. Spunt, Mar...> ;Cancer Cell. 2013 Dec 9
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