Skip to main content
Ellen Gravallese, MD, Rheumatology, Boston, MA, Brigham and Women's Hospital

EllenMGravalleseMD

Rheumatology • Boston, MA

Rheumatoid Arthritis & Related, Spondyloarthropathy

Chief, Division of Rheumatology, Inflammation, and Immunity Brigham and Women's Hospital, Harvard Medical School

Join to view full profile

Dr. Gravallese is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

  • Connect with other colleagues in the same hospital or clinic
  • Search all U.S. specialist profiles and refer a patient
  • Read the latest clinical news and earn CME/CEU credits

See Dr. Gravallese's full profile

Already have an account?

  • Office

    Brigham and Women's Hospital
    Hale Building for Transformative Medicine; 60 Fenwood Road
    Boston, MA 02115
    Phone+1 617-525-1000
  • Is this information wrong?

Summary

  • Dr. Ellen M. Gravallese is the Theodore Bevier Bayles Professor of Medicine at Harvard Medical School and Chair of Rheumatology, Inflammation, and Immunity at Brigham and Women's Hospital. Her prior position was as the Myles J. McDonough Chair in Rheumatology, tenured Professor of Medicine and Chief of Rheumatology at University of Massachusetts Medical School. Dr. Gravallese received her AB degree from Harvard College and her MD from Columbia University College of Physicians and Surgeons. She completed a combined residency in Internal Medicine and Pathology at Brigham and Women’s Hospital, Harvard Medical School, where she also served as a fellow in the Division of Rheumatology, Immunology and Allergy. She is Board Certified in Anatomic Pathology, Internal Medicine and Rheumatology. Dr. Gravallese’s career focus has been in the areas of basic science investigation, the care of patients with rheumatic disease, and the training of young investigators. Dr. Gravallese’s basic science laboratory has been devoted for the past 20 years to the study of the pathogenesis of rheumatoid arthritis (RA), with a particular interest in the fundamental mechanisms of bone and cartilage destruction.

Education & Training

  • Brigham and Women's Hospital
    Brigham and Women's HospitalFellowship, Rheumatology, 1986 - 1989
  • Brigham and Women's Hospital
    Brigham and Women's HospitalResidency, Internal Medicine, 1981 - 1986
  • Columbia University Vagelos College of Physicians and Surgeons
    Columbia University Vagelos College of Physicians and SurgeonsClass of 1981
  • Harvard University
    Harvard UniversityA.B., Biochemical Sciences, Magna Cum Laude, 1977
  • Harvard University
    Harvard UniversityA.B., Biochemical Sciences, Summa Cum Laude, 1977

Certifications & Licensure

  • MA State Medical License
    MA State Medical License 1982 - 2025
  • American Board of Internal Medicine Internal Medicine
  • American Board of Internal Medicine Rheumatology
  • American Board of Pathology Anatomic Pathology

Awards, Honors, & Recognition

  • Carol Nachman Prize International research award, 2019
  • Stephen M. Krane Award ASBMR, 2017
  • Marion Ropes Award Arthritis Foundation, 2012
  • Join now to see all

Clinical Trials

Publications & Presentations

PubMed

Journal Articles

  • PRIME Time in Rheumatoid Arthritis  
    Ellen M Gravallese, William H Robinson, The New England Journal of Medicine
  • Effects of the IL-23–IL-17 Pathway on Bone in Spondyloarthritis  
    Ellen Gravallese, MD, Nature
  • Methods for High-Dimensonal Analysis of Cells Dissociated from Cyropreserved Synovial Tissue  
    Paul J Utz, William H Robinson, Ellen M Gravallese, Soumya Raychaudhuri, Alessandra B Pernis, Susan M Goodman, Michael B Brenner, Lionel B Ivashkiv, Brendan F Boyce, P..., BioMed Central
  • Join now to see all

Books/Book Chapters

  • UpToDate 
    Chapter: Synovial tissue analysis in rheumatoid arthritis, I and II. 
    Chopra R and Gravallese EMEditors: Rose BD.UpToDate, Wellesley, MA2014
  • Rheumatology 
    Chapter: Chapter 91, “The rheumatoid joint: Synovitis and tissue destruction.” 
    Gravallese EM and Monach PAEditors: Hochberg, Silman, Smolen, Weinblatt, Weisman.Mosby: An Imprint of Elsevier ScienceEdition 5th,2013
  • Rheumatology 
    Chapter: The rheumatoid joint: Synovitis and tissue destruction 
    Gravallese EM and Monach PAEditors: Hochberg, Silman, Smolen, Weinblatt, Weisman.Mosby: An Imprint of Elsevier ScienceEdition 5th,2013
  • Join now to see all

Abstracts/Posters

  • The STING Pathway Regulates Bone Remodeling in a Model of Autoimmune Disease. Plenary Abstract Presentation
    Gravallese E, American College of Rheumatology National Meeting, Boston, MA, 1/1/2014
  • The STING Pathway Regulates Bone Remodeling in a Model of Autoimmune Disease
    American College of Rheumatology national meeting, Boston, MA, 1/1/2014
  • DNA sensors regulate inflammation in a model of autoimmune arthritis
    American College of Rheumatology national meeting, Boston, MA, 1/1/2014
  • Join now to see all

Lectures

  • RA pathogenesis and the bone perspective 
    1/1/2015
  • What can we learn from synovial tissue in rheumatic diseases? 
    1/1/2015
  • Mechanisms of bone formation and the potential for erosion repair 
    Nice, France - 1/1/2015
  • Join now to see all

Other

  • Radio interview, with Dr. David Borenstein, on current research efforts in rheumatoid arthritis. 
    Gravallese E, Speaking of Health
    Washington, DC - 1/1/2014
  • Synovial tissue analysis in rheumatoid arthritis, I and II 
    Gravallese EM, Handel ML, UpToDate
    Wellesley, MA - 1/1/2004
  • Discussion of pathogenic mechanisms of joint destruction in RA and implications for therapy. 
    Gravallese E, Rheumaview Series
    JointandBone.org
    1/1/2002

Authored Content

  • Leveraging the ACR’s RISE Registry for ResearchSeptember 2020
  • PRIME Time in Rheumatoid ArthritisJuly 2020
  • The ACR Is Helping Rheumatology Practices Meet COVID-19 ChallengesJuly 2020
  • The ACR Is Helping Rheumatology Practices Meet COVID-19 ChallengesJuly 2020
  • Join now to see all

Press Mentions

  • Drug May Offer New Approach Against Rheumatoid Arthritis
    Drug May Offer New Approach Against Rheumatoid ArthritisMay 18th, 2023
  • Themes of Drama, Heroism & New Challenges Threaded President’s & Keynote Addresses at ACR Convergence 2022
    Themes of Drama, Heroism & New Challenges Threaded President’s & Keynote Addresses at ACR Convergence 2022November 18th, 2022
  • A New President Takes the ACR Helm: Introducing Douglas White, MD, PhD
    A New President Takes the ACR Helm: Introducing Douglas White, MD, PhDNovember 17th, 2022
  • Join now to see all

Grant Support

  • Inhibition Of Osteoblast Function In Bone Erosion In Rheumatoid ArthritisNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2009–2011
  • Pathogenesis Of Bone Erosion In Rheumatoid ArthritisNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2007
  • Pathogenesis Of Bone Erosion In Rheumatoid ArthritisNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2003–2006
  • Role Of Lipopolysaccharide In Connective Tissue DiseaseNational Institute Of Arthritis And Musculoskeletal And Skin Diseases1989–1993

Professional Memberships

Hospital Affiliations

Dr. Ellen Gravallese, Dr. Ellen Gravallese, MD, Dr. E Gravallese, Dr. Ellen M Gravallese