EmilyE(Ray)Ray KoMD

PubMed

• 10 citations
  Average Weighted Accuracy: Pragmatic Analysis for a Rapid Diagnostics in Categorizing Acute Lung Infections (RADICAL) Study.
  Ying Liu, Ephraim L. Tsalik, Yunyun Jiang, Emily R Ko, Christopher W. Woods, Ricardo Henao, Scott R. Evans> ;Clinical Infectious Diseases. 2020 Jun 10
• 165 citations
  Host gene expression classifiers diagnose acute respiratory illness etiology.
  Ephraim L. Tsalik, Ricardo Henao, Marshall Nichols, Thomas W. Burke, Emily R Ko, Micah T. McClain, Lori L. Hudson, Anna Mazur, D. Freeman, Tim Veldman, Raymond J. Lang...> ;Science Translational Medicine. 2016 Jan 20
• 29 citations
  Discriminating Bacterial and Viral Infection Using a Rapid Host Gene Expression Test
  Ephraim L. Tsalik, Ricardo Henao, Montgomery Jesse Linton, Jeff Nawrocki, Mert Aydin, Emily Lydon, Emily R Ko, Elizabeth Petzold, Bradly P. Nicholson, Charles B. Cairn...> ;Critical Care Medicine. 2021 Apr 28
• 3 citations
  Single-cell genome-wide association reveals that a nonsynonymous variant inconfers increased susceptibility to influenza virus.
  Benjamin H Schott, Liuyang Wang, Xinyu Zhu, Alfred T Harding, Emily R Ko, Jeffrey S Bourgeois, Erica J Washington, Thomas W Burke, Jack Anderson, Emma Bergstrom, Zoe G...> ;Cell Genomics. 2022 Nov 9
• Efficacy and safety of azithromycin versus placebo to treat lower respiratory tract infections associated with low procalcitonin: a randomised, placebo-controlled, dou...
  Tsalik EL, Rouphael NG, Sadikot RT, Rodriguez-Barradas MC, McClain MT, Wilkins DM, Woods CW, Swamy GK, Walter EB, El Sahly HM, Keitel WA, Mulligan MJ, Tuyishimire B, S...> ;The Lancet. Infectious diseases. 2022-12-13
• 2 citations
  Host Gene Expression to Predict Sepsis Progression.
  Cassandra Fiorino, Yiling Liu, Ricardo Henao, Emily R Ko, Thomas W Burke, Geoffrey S Ginsburg, Micah T McClain, Christopher W Woods, Ephraim L Tsalik> ;Critical Care Medicine. 2022 Dec 1
• 9 citations
  Infliximab for Treatment of Adults Hospitalized with Moderate or Severe Covid-19.
  Jane A O'Halloran, Eyal Kedar, Kevin J Anstrom, Matthew W McCarthy, Emily R Ko, Patricia Segura Nunez, Cynthia Boucher, P Brian Smith, Reynold A Panettieri, Sabina Men...> ;Medrxiv. 2022 Sep 26
• 7 citations
  Abatacept for Treatment of Adults Hospitalized with Moderate or Severe Covid-19.
  Emily R Ko, Kevin J Anstrom, Reynold A Panettieri, Anne M Lachiewicz, Martin Maillo, Jane A O'Halloran, Cynthia Boucher, P Brian Smith, Matthew W McCarthy, Patricia Se...> ;Medrxiv. 2022 Sep 26
• 56 citations
  Baricitinib versus dexamethasone for adults hospitalised with COVID-19 (ACTT-4): a randomised, double-blind, double placebo-controlled trial.
  Maves, R., Wang, J. P., Castro, J. G., Yang, O. O., Cameron R Wolfe, Kay M Tomashek, Thomas F Patterson, Carlos A Gomez, Vincent C Marconi, Mamta K Jain, Otto O Yang, ...> ;The Lancet. Respiratory Medicine. 2022 Sep 1
• The Association of Baseline Plasma SARS-CoV-2 Nucleocapsid Antigen Level and Outcomes in Patients Hospitalized With COVID-19.
  ACTIV-3/TICO Study Group, Rogers AJ, Wentworth D, Phillips A, Shaw-Saliba K, Dewar RL, Aggarwal NR, Babiker AG, Chang W, Dharan NJ, Davey VJ, Higgs ES, Gerry N, Ginde ...> ;Annals of internal medicine. 2022-08-30
• A New Era in Host Response Biomarkers to Guide Precision Medicine for Infectious Diseases.
  Emily R Ko, Ephraim L Tsalik> ;Journal of the Pediatric Infectious Diseases Society. 2022 Dec 5
• Efficacy and Safety of Ensovibep for Adults Hospitalized With COVID-19 : A Randomized Controlled Trial.
  ACTIV-3/TICO Study Group, Barkauskas C, Mylonakis E, Poulakou G, Young BE, Vock DM, Siegel L, Engen N, Grandits G, Mosaly NR, Vekstein AM, Rogers R, Shehadeh F, Kaczyn...> ;Annals of internal medicine. 2022-08-09
• 7 citations
  Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion.
  Nicholas S Giroux, Shengli Ding, Micah T McClain, Thomas W Burke, Elizabeth Petzold, Hong A Chung, Grecia O Rivera, Ergang Wang, Rui Xi, Shree Bose, Tomer Rotstein, Br...> ;Scientific Reports. 2022 Jul 9
• 11 citations
  Prospective Validation of a Rapid Host Gene Expression Test to Discriminate Bacterial From Viral Respiratory Infection.
  Emily R Ko, Ricardo Henao, Katherine Frankey, Elizabeth A Petzold, Pamela D Isner, Anja K Jaehne, Nakia Allen, Jayna Gardner-Gray, Gina Hurst, Jacqueline Pflaum-Carlso...> ;JAMA Network Open. 2022 Apr 1
• 15 citations
  Systematic comparison of published host gene expression signatures for bacterial/viral discrimination.
  Nicholas Bodkin, Melissa Ross, Micah T McClain, Emily R Ko, Christopher W Woods, Geoffrey S Ginsburg, Ricardo Henao, Ephraim L Tsalik> ;Genome Medicine. 2022 Feb 21
• Efficacy and safety of two neutralising monoclonal antibody therapies, sotrovimab and BRII-196 plus BRII-198, for adults hospitalised with COVID-19 (TICO): a randomise...
  ACTIV-3/Therapeutics for Inpatients with COVID-19 (TICO) Study Group> ;The Lancet. Infectious diseases. 2021-12-23
• Responses to a Neutralizing Monoclonal Antibody for Hospitalized Patients With COVID-19 According to Baseline Antibody and Antigen Levels : A Randomized Controlled Trial.
  ACTIV-3/TICO Bamlanivimab Study Group, Lundgren JD, Grund B, Barkauskas CE, Holland TL, Gottlieb RL, Sandkovsky U, Brown SM, Knowlton KU, Self WH, Files DC, Jain MK, B...> ;Annals of internal medicine. 2021-12-21
• 3 citations
  A comparison of host response strategies to distinguish bacterial and viral infection.
  Melissa Ross, Ricardo Henao, Thomas W Burke, Emily R Ko, Micah T McClain, Geoffrey S Ginsburg, Christopher W Woods, Ephraim L Tsalik> ;Plos One. 2021 Jan 1
• 1 citations
  Comparing the Diagnostic Accuracy of Clinician Judgment to a Novel Host Response Diagnostic for Acute Respiratory Illness.
  Ian S Jaffe, Anja K Jaehne, Eugenia Quackenbush, Emily R Ko, Emanuel P Rivers, Micah T McClain, Geoffrey S Ginsburg, Christopher W Woods, Ephraim L Tsalik> ;Open Forum Infectious Diseases. 2021 Dec 1
• 13 citations
  The Host Response to Viral Infections Reveals Common and Virus-Specific Signatures in the Peripheral Blood.
  Ephraim L. Tsalik, Cassandra Fiorino, Ammara Aqeel, Yiling Liu, Ricardo Henao, Emily R Ko, Thomas W. Burke, Megan E. Reller, Champica K Bodinayake, Ajith Nagahawatte, ...> ;Frontiers in Immunology. 2021 Oct 27
• 96 citations
  Efficacy of interferon beta-1a plus remdesivir compared with remdesivir alone in hospitalised adults with COVID-19: a double-bind, randomised, placebo-controlled, phas...
  Andre C. Kalil, Aneesh K. Mehta, Thomas F Patterson, Nathaniel B. Erdmann, Carlos A. Gomez, Mamta K. Jain, Cameron R. Wolfe, Guillermo M. Ruiz-Palacios, Susan Kline, J...> ;The Lancet. Respiratory Medicine. 2021 Oct 18
• 2 citations
  Rationale and design of the prone position and respiratory outcomes in non-intubated COVID-19 patients: The "PRONE" study.
  , , , , , , , , , , , , , , , > ;Contemporary Clinical Trials. 2021 Aug 13
• 21 citations
  An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility.
  Liuyang Wang, Thomas J Balmat, Alejandro L. Antonia, Florica J Constantine, Ricardo Henao, Thomas W. Burke, Andy Ingham, Micah T. McClain, Ephraim L. Tsalik, Emily R K...> ;Genome Medicine. 2021 May 17
• A Neutralizing Monoclonal Antibody for Hospitalized Patients with Covid-19.
  ACTIV-3/TICO LY-CoV555 Study Group, Lundgren JD, Grund B, Barkauskas CE, Holland TL, Gottlieb RL, Sandkovsky U, Brown SM, Knowlton KU, Self WH, Files DC, Jain MK, Benf...> ;The New England journal of medicine. 2020-12-22
• 4 citations
  Previously Derived Host Gene Expression Classifiers Identify Bacterial and Viral Etiologies of Acute Febrile Respiratory Illness in a South Asian Population.
  L. Gayani Tillekeratne, Sunil Suchindran, Emily R Ko, Elizabeth Petzold, Champica K Bodinayake, Ajith Nagahawatte, Vasantha Devasiri, Ruvini Kurukulasooriya, Bradly P....> ;Open Forum Infectious Diseases. 2020 May 26
• Join now to see all