EngMengTanMD

PubMed

• 2 citations
  Henry G Kunkel and Rheumatoid Factor.
  Eng M. Tan> ;Annals of the Rheumatic Diseases. 2019 Jul 1
• 20 citations
  Early detection of hepatocellular carcinoma using autoantibody profiles from a panel of tumor-associated antigens
  James A. Koziol, Haruhiko Imai, Liping Dai, Jianying Zhang, Eng M. Tan> ;Cancer Immunology, Immunotherapy. 2018 Mar 1
• 41 citations
  Identification of autoantibodies to ECH1 and HNRNPA2B1 as potential biomarkers in the early detection of lung cancer.
  Liping Dai, Jitian Li, Jun Chieh J. Tsay, Ting An Yie, John S. Munger, Harvey I. Pass, William N. Rom, Eng M. Tan, Jianying Zhang> ;Oncoimmunology. 2017 Mar 31
• 69 citations
  Historical observations contributing insights on etiopathogenesis of rheumatoid arthritis and role of rheumatoid factor
  Eng M. Tan, Josef S Smolen> ;The Journal of Experimental Medicine. 2016 Sep 19
• 51 citations
  Autoantibodies against tumor-associated antigens in the early detection of lung cancer
  Liping Dai, Jun Chieh J. Tsay, Jitian Li, Ting An Yie, John S. Munger, Harvey I. Pass, William N. Rom, Yi Zhang, Eng M. Tan, Jianying Zhang> ;Lung Cancer. 2016 Sep 1
• 11 citations
  Tumor-associated antigen CAPERα and microvessel density in hepatocellular carcinoma.
  Liping Dai, Xuan Xian Peng, Eng M. Tan, Jianying Zhang> ;Oncotarget. 2016 Feb 25
• 40 citations
  Using immunomic approach to enhance tumor-associated autoantibody detection in diagnosis of hepatocellular carcinoma.
  Liping Dai, Pengfei Ren, Mei Liu, Haruhiko Imai, Eng M. Tan, Jianying Zhang> ;Clinical Immunology. 2014 May 1
• 10 citations
  Antinuclear antibodies defining autoimmunity pathways
  Eng M. Tan> ;Arthritis Research & Therapy. 2014 Feb 12
• 28 citations
  Autoantibodies, autoimmune disease, and the birth of immune diagnostics
  Eng M. Tan> ;The Journal of Clinical Investigation. 2012 Nov 1
• 51 citations
  Overexpression of the IGF2-mRNA binding protein p62 in transgenic mice induces a steatotic phenotype
  Elisabeth Tybl, Fu Dong Shi, Sonja M. Kessler, Sascha Tierling, Jörn Walter, Rainer M. Bohle, Stefan Wieland, Jianying Zhang, Eng M. Tan, Alexandra K. Kiemer> ;Journal of Hepatology. 2011 May 1
• 107 citations
  PBC Screen An IgG/IgA dual isotype ELISA detecting multiple mitochondrial and nuclear autoantibodies specific for primary biliary cirrhosis
  Haiying Liu, Gary L. Norman, Zakera Shums, Howard J. Worman, Edward L. Krawitt, Nicola Bizzaro, Diego Vergani, Dimitrios P. Bogdanos, George N. Dalekos, Piotr Milkiewi...> ;Journal of Autoimmunity. 2010 Dec 1
• 34 citations
  Identification of an autoantibody panel to separate lung cancer from smokers and nonsmokers
  William N. Rom, Judith D. Goldberg, Doreen Addrizzo-Harris, Heather N. Watson, Michael Khilkin, Alissa K. Greenberg, David P. Naidich, Bernard Crawford, Ellen Eylers, ...> ;BMC Cancer. 2010 May 26
• 72 citations
  Autoantibodies to tumor-associated antigens as diagnostic biomarkers in hepatocellular carcinoma and other solid tumors.
  Jianying Zhang, Eng M. Tan> ;Expert Review of Molecular Diagnostics. 2010 Apr 1
• 43 citations
  Autoantibodies to tumor-associated antigens combined with abnormal alpha-fetoprotein enhance immunodiagnosis of hepatocellular carcinoma
  Yao Chen, Yusen Zhou, Suimin Qiu, Kaijuan Wang, Siwei Liu, Xuan Xian Peng, Junfeng Li, Eng M. Tan, Jianying Zhang> ;Cancer Letters. 2010 Mar 1
• 1 citations
  Autoantibodies to nuclear proteins and ribonucleoprotein.
  Eng M. Tan> ;Acta Medica Scandinavica. Supplementum. 2009 Apr 24
• 14 citations
  Identification of tumor-associated antigens as diagnostic and predictive biomarkers in cancer.
  Jianying Zhang, Kok Sun Looi, Eng M. Tan> ;Methods in Molecular Biology. 2009 Jan 1
• 59 citations
  Using Proteomic Approach to Identify Tumor-Associated Antigens as Markers in Hepatocellular Carcinoma
  Kok Sun Looi, Ernesto S. Nakayasu, Raquel A. De Diaz, Eng M. Tan, Igor C. Almeida, Jianying Zhang> ;Journal of Proteome Research. 2008 Aug 2
• 187 citations
  Autoantibodies to tumor-associated antigens: reporters from the immune system.
  Eng M. Tan, Jianying Zhang> ;Immunological Reviews. 2008 Apr 1
• 27 citations
  Cyclin B1 is commonly expressed in the cytoplasm of primary human acute myelogenous leukemia cells and serves as a leukemia-associated antigen associated with autoanti...
  Elisabeth Ersvær, Jianying Zhang, Emmet McCormack, Astrid Marta Olsnes, Nina Anensen, Eng M. Tan, Bjørn Tore Gjertsen, Øystein Bruserud> ;European Journal of Haematology. 2007 Sep 1
• 79 citations
  Antibody Detection Using Tumor-Associated Antigen Mini-Array in Immunodiagnosing Human Hepatocellular Carcinoma
  Jianying Zhang, Roxanne Megliorino, Xuan Xian Peng, Eng M. Tan, Yao Chen, Edward K. L. Chan> ;Journal of Hepatology. 2007 Jan 1
• 110 citations
  Tumor-associated Antigen Arrays for the Serological Diagnosis of Cancer
  Carlos A. Casiano, Melanie Mediavilla-Varela, Eng M. Tan> ;Molecular & Cellular Proteomics. 2006 Oct 1
• 34 citations
  Analyses of autoantibodies against tumor-associated antigens in patients with hepatocellular carcinoma
  Takashi Himoto, Shigeki Kuriyama, Jianying Zhang, Edward K. L. Chan, Yasuhiko Kimura, Tsutomu Masaki, Naohito Uchida, Mikio Nishioka, Eng M. Tan> ;International Journal of Oncology. 2005 Oct 1
• 30 citations
  Identification of kinectin as a novel Behcet's disease autoantigen.
  Yu Lu, Ping Ye, Shun-le Chen, Eng M. Tan, Edward K. L. Chan> ;Arthritis Research & Therapy. 2005 Jul 27
• 49 citations
  Preferential humoral immune response in prostate cancer to cellular proteins p90 and p62 in a panel of tumor-associated antigens.
  Fu Dong Shi, Jianying Zhang, Daorong Liu, Ann Rearden, Max L. Elliot, Dan Nachtsheim, Tracy R. Daniels, Carlos A. Casiano, Mary J. Heeb, Edward K. L. Chan, Eng M. Tan> ;The Prostate. 2005 May 15
• 28 citations
  Significance of autoantibodies against insulin-like growth factor II mRNA-binding proteins in patients with hepatocellular carcinoma.
  Takashi Himoto, Shigeki Kuriyama, Jianying Zhang, Edward K. L. Chan, Mikio Nishioka, Eng M. Tan> ;International Journal of Oncology. 2005 Feb 1
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Journal Articles

• Action spectrum of ultra¬violet light- induced damage to nuclear DNA in vivo.  
  Tan, E.M., R.G. Freeman and R.B. Stoughton, J Invest Derm 55
• In vivo and in vitro production of anti-histone antibodies in NZB/NZW mice.  
  Gioud, M., B.L. Kotzin, R.L. Rubin, F.G. Joslin and E.M. Tan, J Immunol
• An improved ELISA for anti-native DNA by elimination of interference by anti-histone antibodies.  
  Rubin, R.L., F.G. Joslin and E.M. Tan, J Immunol Methods
• Identification of a La protein binding site in a RNA polymerase III transcript (4.5 I RNA).  
  Reddy, R., D. Henning, E. Tan and H. Busch, J Biol Chem
• Antibodies from patients with mixed connective tissue disease react with heterogeneous nuclear ribonucleoprotein or ribonucleic acid (hnRNP/RNA) of the nuclear matrix.  
  Fritzler, M.H., R. Ali and E.M. Tan, J Immunol
• Identification of the SS- A(Ro) intracellular antigen with autoimmune sera.  
  Lieu, T.S., M. Jiang, J.C. Steigerwald and E.M. Tan, J Immunol Methods
• Multiple autoantigen binding capabilities of mouse monoclonal antibodies selected for rheumatoid factor activity.  
  Rubin, R.L., R. Baldares, E.M. Tan, F.J. Dixon and A. Theofilopoulos, J Exp Med
• Standardization of the immunofluorescence test for autoantibody to nuclear antigens (ANA): Use of reference sera of defined antibody specificity.  
  Molden, D.P., R. M. Nakamura and E.M. Tan, Am J Clin Path
• Anti-native DNA antibodies from autoimmune sera also bind to DNA in mitochondria.  
  Reimer, G., R.L. Rubin, B.L. Kotzin and E.M. Tan, J Immunol
• Monoclonal anti-histone antibodies derived from murine models of lupus.  
  Kotzin, B.L., J.A. Lafferty, J.P. Portanova, R.L. Rubin and E.M. Tan, J Immunol
• Autoallergic reactions induced by procainamide.  
  Tan, E.M. and R.L. Rubin, J Allergy Clin Immunol
• Immunological detection of thymidine photoproduct formation in vivo.  
  Natali, P.G. and E.M. Tan, Radiation Res 46
• Experimental renal disease induced by DNA-anti-DNA immune complexes.  
  Natali, P.G. and E.M. Tan, J Clin Invest 51
• Precipitin reactions between polyribonucleotides and heat labile serum factors.  
  Natali, P.G. and E.M. Tan, J Immunol
• Differentiation of antinuclear antibodies giving speckled staining patterns in immunofluorescence.  
  Northway, J.D. and E.M. Tan, Clin Immunol Immunopathol
• Identification of ribosomal protein autoantigens.  
  Francoeur, A.M., C.L. Peebles, K.J. Heckman, J.C. Lee and E.M. Tan, J Immunol
• An immunologic approach to the fate of nuclear and nucleolar macromolecules during the cell cycle.  
  Tan, E.M. and R.A. Lerner, J Mol Biol 68
• Purification and N-terminal amino acid sequence of proliferating cell nuclear antigen (PCNA)/cyclin and development of ELISA for anti-PCNA antibodies.  
  Ogata, K., Y. Ogata, R.M. Nakamura and E.M. Tan, J Immunol
• Clinical profiles of bronchial asthma.  
  Mathison, D.A., D.D. Stevenson, E.M. Tan and J.H. Vaughan, J Am Med Assoc 224
• Purification and partial characterization of a nucleolar scleroderma antigen (Mr = 34,000; pI = 8.5) rich in NG, NG-dimethylarginine.  
  .Lischwe, M.A., R.L. Ochs, R. Reddy, R.G. Cook, L.C. Yeoman, E.M. Tan, M. Reichlin and H. Busch, J Biol Chem
• Molecular definition and sequence motifs of the 52 kD component of human SS-A/Ro autoantigen.  
  Chan, E.K.L., Hamel, J.C., Buyon, J.P., and E.M. Tan, J Clin Invest
• Effect of actinomycin D on the expression of nuclear antigen SS-B/La.  
  Deng, J-S. and Tan, E.M, J Invest Derm
• Molecular characterization of an autoantigen of PM¬Scl in the polymyositis/scleroderma overlap syndrome. A unique and complete human cDNA encoding an apparent 75 kD ac...  
  Alderuccio, F., Chan, E.K.L. and E.M. Tan, J Exp Med
• Microhemagglutination tests for detection of native and single-stranded DNA antibodies and circulating DNA antigen.  
  Inami, Y.H., R.M. Nakamura and E.M. Tan, J Immunol Methods 3
• Identification of Ki (Ku, p70/p80) autoantigens and analysis of anti-Ki autoantibody reactivity.  
  Francoeur, A.M., C.L. Peebles, P.T. Gompper and E.M. Tan, J. Immunol
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Books/Book Chapters

• Production of potentially antigenic DNA in cells. 
  Chapter: VIth International Symposium 
  Page 346 - 349Tan, E.MEditors: P.A. Meischer.Grune & Stratton, New York
• Autoantibodies and autoimmunity. 
  Chapter: Encyclopedia of Molecular Biology and Molecular Medicine 
  Page 84 - 93Pollard, K.M., Chan, E.K.L., Rubin, R.L. and E.M. TanEditors: R.A. Meyers.
• Antinuclear antibodies. 
  Chapter: Significance of biochemical specificities 
  Page 367 - 378Tan, E.M. and J.H. VaughanEditors: E.H. Beutner.Hutchinson and Ross
• Proliferating cell nuclear antigen/cyclin. 
  Chapter: Methods in Enzymology 
  Page 147 - 159Ogata, K., Celis, J. and E.M. TanEditors: G. diSabato.
• The importance of the autoantibody –defined epitope. 
  Chapter: Autoantibodies and Autoimmunity: Molecular Mechanisms in Health and Disease 
  Tan, E.MEditors: K.M. Pollard.Wiley – VCH, Weinheim, Germany
• Identification of tumor-associated antigens as diagnostic and predictive markers in Cancer in Methods in Molecular Biology. 
  Zhang, J-Y., Looi, K. S. and Tan, E. MEditors: Tumor Biomarker Discovery, M A. Tainsky.Humana Press, New York
• Autoantibodies, in The ACR at 75. A Diamond Jubilee. D.S.Pisetsky. 
  Page 119 - 124Tan, E.MEditors: Wiley-Blackwell.Hoboken, N.J
• Bronchial asthma: Pathophysiology in asthma. 
  Chapter: Physiology, Immunopathology and Treatment 
  Page 1 - 13Vaughan, J.H., E.M. Tan, D.A. Mathison, D.D. Stevenson, S.Z. Berman and A.I. BrandeEditors: K.F. Austen and L. Lichtenstein.Academic Press
• Sunlight as a potential etiological factor in systemic lupus erythematosus. 
  Chapter: Modern Topics in Rheumatology 
  Page 99 - 106Tan, E.MEditors: G.R.V. Hughes.W. Heinemann Ltd., , London
• Quantitation of antibodies to Sm antigen and nuclear ribonucleoprotein by hemagglutination. 
  Chapter: Manual of Clinical Immunology 
  Page 660 - 664Tan, E.M. and C. PeeblesEditors: N.R. Rose and H. Friedman.Amer. Soc. for Microbiol.,
• Autoantibodies as biological markers. 
  Chapter: Biological Markers of Neoplasia: Basic and Applied Aspects 
  Page 399 - 408Tan, E.M., P. Reyes and M.J. FritzlerEditors: R.W. Ruddon.Elsevier North Holland, Inc.
• Systemic lupus erythematosus. 
  Chapter: Immunological Diseases 
  Page 1038 - 1060Tan, E.M. and N.F. RothfieldEditors: M. Samter.Little Brown Co.,
• Systemic lupus erythematosus-immunologic aspects. 
  Chapter: Arthritis and Allied Conditions 
  Page 715 - 722Tan, E.MEditors: D.J. McCarthy.Lea and Febiger
• Autoimmunity to nuclear antigens. 
  Chapter: The Cell Nucleus 
  Page 457 - 477Tan, E.MEditors: Vol. VII. H. Busch.Academic Press
• Experimental renal disease induced by streptococci. 
  Chapter: The Streptococcus, Rheumatic Fever and Glomerulonephritis 
  Tan, E.MEditors: J.W. Uhr.Williams and Wilkens Co.,, Baltimore
• Human antibodies to RNA-containing particles. 
  Chapter: The Cell Nucleus 
  Page 369 - 387Douvas, A.S. and E.M. TanEditors: Vol. VIII. Nuclear Particles Part A., H. Busch.Academic Press, New York
• Antihistone antibodies induced by procainamide and hydralazine. 
  Chapter: Nephrotoxic Mechanisms of Drugs and Environmental Toxins 
  Page 373 - 381Portanova, J.P., R.L. Rubin, and E.M. TanEditors: G. Porter.Plenum Publ. Corp.,
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Other

• Microvascular abnormalities as possible predictors of disease subsets in Raynaud phenomenon and early connective tissue disease. 
  Maricq, H.R., F.E. Harper, M.M. Khan, E.M. Tan and E.C. Leroy
• Henry George Kunkel 1916-1983. 
  Tan, E.M. In memoriam
• The role of RNP, Sm and SS-A/Ro specific antisera from patients with lupus erythematosus in inducing antibody-dependent cellular cytotoxicity (ADCC) of targets coated ... 
  Norris, D.A., S.R. Ryan, K.A. Fritz, M. Kubo, E.M. Tan, J.S. Deng and W.L. Weston
• Fibrin(ogen)olysis in polymyalgia rheumatica and temporal arteritis: Preliminary findings on association with disease activity. 
  Grau, R.F., S.S. Kassan, J.J. Franks, H. Kaplan, S.H. Walker and E.M. Tan
• Advances in laboratory tests for autoantibodies to nuclear antigens in systemic rheumatic diseases. 
  Nakamura, R.M., Peebles, C.L., Molden, D.P. and E.M. Tan
• Synthesis of small nuclear ribonucleoprotein particles by the malarial parasite Plasmodium falciparum. 
  Francoeur, A.M., Gritzmacher, C.A., Peebles, C.L., Reese, R.T. and E.M. Tan
• Detection of a 140 KDa nucleolar protein with an anti-PCNA autoantibody. 
  Chan, P.-K., Aldrich, M., Tan, E.M. and Busch, H
• Detection and clinical significance of IgM antibody. 
  Pollard, K.M. and E.M. Tan. Purification of the Sm nuclear autoantigen
• IgG antibodies to the histone H2A-H2B complex characterize procainamide-induced lupus. 
  Rubin, R.L., E.M. McNally, S.R. Nusinow, C.A. Robinson and E.M. Tan
• ANAs in systemic rheumatic disease. 
  Tan, E.M., Robinson, C.A. and R.M. Nakamura
• A time for change and a time to remain the same. 
  Tan, E.M
• Immunological reaction in keratoacanthoma, a spontaneously resolving skin tumor. 
  Brown, F.C. and E.M. Tan, Cancer Res 33
• Antinuclear Antibodies and Autoimmunity. 
  Tan, E.M, Encyclopedia of Human Biology
• Antinuclear antibodies and nuclear antigens in rheumatoid synovial fluids. 
  Robitaille, P., N.J. Zvaifler and E.M. Tan, Clin Immunol Immunopathol 1
• IgM anti-histone H3 antibody associated with undifferentiated rheumatic disease syndromes. 
  Molden, D.P., G.L. Klipple, C.L. Peebles, R.L. Rubin, R.M. Nakamura and E.M. Tan
• Polynucleotide specificities of murine monoclonal anti-DNA antibodies. 
  Pollard, K.M., Jones, J.E., Tan, E.M., Theofilopoulos, A.N., Dixon, F.J. and R.L. Rubin
• Molecular cloning and sequence analysis of U3 snoRNA-associated mouse fibrillarin. 
  Turley, S., Tan, E.M. and K.M. Pollard, Biochim Biophys Acta
• Procainamide elicits a selective autoantibody immune response. 
  Rubin, R.L., Reimer, G., McNally, E.M., Nusinow, S.R., Searles, R.P. and E.M. Tan
• Human 60-kDa SS-A/Ro ribonucleoprotein autoantigen gene (SSA 2) localized to 1q31 by fluorescence in situ hybridization. 
  Chan, E.K.L., Tan, E.M., Ward, D.C. and A.G. Matera, Genomics
• Autoantibody to DNA topoisomerase II in primary liver cancer. 
  Imai, H., Furuta, K., Landberg, G., Kiyosawa, K., Liu, L.F. and E.M.Tan, Clin Cancer Res
• Expression of proliferating cell nuclear antigen (PCNA)/cyclin during the cell cycle. 
  Kurki, P., Vanderlaan, M., Dolbeare, F., Gray, J. and E.M. Tan
• Nuclear autoantigen p330d/CENP-F - a marker for cell proliferation in human malignancies. 
  Landberg, G., Erlanson, M., Roos, G., Tan, E.M. and C.A. Casiano
• Recent developments in the understanding of antinuclear antibodies. 
  Casiano, C.A. and E.M. Tan, Int Arch Allergy Immunol
• What do they recognize? 
  Tan, E.M. Autoantibodies, Verh Dtsch Ges Path
• Antinuclear antibodies: probes to defining proteolytic events associated with apoptosis. 
  Casiano, C.A. and E.M. Tan, Mol Biol Rpts
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