EnnioAntonioChioccaMD

PubMed

• Cerebellar High-Grade Glioma: A Translationally Oriented Review of the Literature.
  Ashley L B Raghu, Jason A Chen, Pablo A Valdes, Walid Ibn Essayed, Elizabeth Claus, Omar Arnaout, Timothy R Smith, E Antonio Chiocca, Pier Paolo Peruzzi, Joshua D Bern...> ;Cancers. 2022 Dec 28
• 7 citations
  Dual Immunostimulatory Pathway Agonism through a Synthetic Nanocarrier Triggers Robust Anti-Tumor Immunity in Murine Glioblastoma.
  Sophie Lugani, Elias A Halabi, Juhyun Oh, Rainer H Kohler, Hannah M Peterson, Xandra O Breakefield, E Antonio A Chiocca, Miles A Miller, Christopher S Garris, Ralph We...> ;Advanced Materials. 2023 Feb 1
• 35 citations
  The emerging field of oncolytic virus-based cancer immunotherapy.
  Rui Ma, Zhenlong Li, E Antonio Chiocca, Michael A Caligiuri, Jianhua Yu> ;Trends in Cancer. 2023 Feb 1
• 17 citations
  Specific targeting of glioblastoma with an oncolytic virus expressing a cetuximab-CCL5 fusion protein via innate and adaptive immunity.
  Lei Tian, Bo Xu, Yuqing Chen, Zhenlong Li, Jing Wang, Jianying Zhang, Rui Ma, Shuai Cao, Weidong Hu, E Antonio Chiocca, Balveen Kaur, Michael A Caligiuri, Jianhua Yu> ;Nature Cancer. 2022 Nov 1
• 16 citations
  Variants of the adeno-associated virus serotype 9 with enhanced penetration of the blood-brain barrier in rodents and primates.
  Yizheng Yao, Jun Wang, Yi Liu, Yuan Qu, Kaikai Wang, Yang Zhang, Yuxin Chang, Zhi Yang, Jie Wan, Junfeng Liu, Hiroshi Nakashima, Sean E Lawler, E Antonio Chiocca, Choi...> ;Nature Biomedical Engineering. 2022 Nov 1
• 4 citations
  Perturbing DDR signaling enhances cytotoxic effects of local oncolytic virotherapy and modulates the immune environment in glioma.
  Marilin S Koch, Mykola Zdioruk, Michal O Nowicki, Alec M Griffith, Estuardo Aguilar-Cordova, Laura K Aguilar, Brian W Guzik, Francesca Barone, Paul Peter Tak, Katharin...> ;Molecular Therapy Oncolytics. 2022 Sep 15
• 6 citations
  Treat and repeat: oncolytic virus therapy for brain cancer.
  John D Christie, E Antonio Chiocca> ;Nature Medicine. 2022 Aug 1
• 1 citations
  Carole A. Miller, MD: Matriarch of the Ohio State University's Department of Neurosurgery.
  Daniel S Ikeda, E Antonio Chiocca, Russel R Lonser, Tracy E Sutton, John M McGregor, Gary L Rea, Victoria A Schunemann, Laura B Ngwenya, Evan S Marlin, Paul N Porensky...> ;World Neurosurgery. 2022 Oct 1
• 35 citations
  STING activation promotes robust immune response and NK cell-mediated tumor regression in glioblastoma models.
  Gilles Berger, Erik H Knelson, Jorge L Jimenez-Macias, Michal O Nowicki, Saemi Han, Eleni Panagioti, Patrick H Lizotte, Kwasi Adu-Berchie, Alexander Stafford, Nikolaos...> ;Proceedings of the National Academy of Sciences of the United States of America. 2022 Jul 12
• 15 citations
  Clinical utility of targeted next-generation sequencing assay in IDH-wildtype glioblastoma for therapy decision-making.
  Mary Jane Lim-Fat, Gilbert C Youssef, Mehdi Touat, J Bryan Iorgulescu, Sydney Whorral, Marie Allen, Rifaquat Rahman, Ugonma Chukwueke, J Ricardo McFaline-Figueroa, Lak...> ;Neuro-Oncology. 2022 Jul 1
• The current state of glioma data registries.
  Alexander G Yearley, Julian Bryan Iorgulescu, Ennio Antonio Chiocca, Pier Paolo Peruzzi, Timothy R Smith, David A Reardon, Michael A Mooney> ;Neuro-Oncology Advances. 2022 Jun 24
• 15 citations
  Agent-based computational modeling of glioblastoma predicts that stromal density is central to oncolytic virus efficacy.
  Adrianne L Jenner, Munisha Smalley, David Goldman, William F Goins, Charles S Cobbs, Ralph B Puchalski, E Antonio Chiocca, Sean Lawler, Paul Macklin, Aaron Goldman, Mo...> ;Iscience. 2022 Jun 17
• 6 citations
  Target receptor identification and subsequent treatment of resected brain tumors with encapsulated and engineered allogeneic stem cells.
  Deepak Bhere, Sung Hugh Choi, Pim van de Donk, David Hope, Kiki Gortzak, Amina Kunnummal, Jasneet Khalsa, Esther Revai Lechtich, Clemens Reinshagen, Victoria Leon, Nab...> ;Nature Communications. 2022 May 19
• 82 citations
  Advances in local therapy for glioblastoma - taking the fight to the tumour.
  Thomas S van Solinge, Lisa Nieland, E Antonio Chiocca, Marike L D Broekman> ;Nature Reviews. Neurology. 2022 Apr 1
• 18 citations
  NOTCH-Induced MDSC Recruitment after oHSV Virotherapy in CNS Cancer Models Modulates Antitumor Immunotherapy.
  Yoshihiro Otani, Ji Young Yoo, Cole T Lewis, Samantha Chao, Jessica Swanner, Toshihiko Shimizu, Jin Muk Kang, Sara A Murphy, Kimberly Rivera-Caraballo, Bangxing Hong, ...> ;Clinical Cancer Research. 2022 Apr 1
• 41 citations
  Immune Checkpoint Inhibition in GBM Primed with Radiation by Engineered Extracellular Vesicles.
  Tian Tian, Ruyu Liang, Gulsah Erel-Akbaba, Lorenzo Saad, Pierre J Obeid, Jun Gao, E Antonio Chiocca, Ralph Weissleder, Bakhos A Tannous> ;ACS Nano. 2022 Feb 22
• 14 citations
  Tumor-Associated Macrophages/Microglia in Glioblastoma Oncolytic Virotherapy: A Double-Edged Sword.
  Sarah E Blitz, Ari D Kappel, Florian A Gessler, Neil V Klinger, Omar Arnaout, Yi Lu, Pier Paolo Peruzzi, Timothy R Smith, Ennio A Chiocca, Gregory K Friedman, Joshua D...> ;International Journal of Molecular Sciences. 2022 Feb 4
• 7 citations
  Systemic high-dose dexamethasone treatment may modulate the efficacy of intratumoral viral oncolytic immunotherapy in glioblastoma models.
  Marilin S Koch, Mykola Zdioruk, Michal O Nowicki, Alec M Griffith, Estuardo Aguilar, Laura K Aguilar, Brian W Guzik, Francesca Barone, Paul P Tak, Ghazaleh Tabatabai, ...> ;Journal for Immunotherapy of Cancer. 2022 Jan 1
• 3 citations
  Combined immunotherapy with controlled Interleukin-12 gene therapy and immune checkpoint blockade in recurrent glioblastoma: an open-label, multi-institutional phase 1...
  E. Antonio Chiocca, Arnold Gelb, Clark C. Chen, Ganesh Rao, David A. Reardon, Patrick Y. Wen, Wenya Linda Bi, Pierpaolo Peruzzi, Christina Amidei, Dan Triggs, Leah Sef...> ;Neuro-Oncology. 2021 Nov 26
• 24 citations
  Quantitative imaging of apoptosis following oncolytic virotherapy by magnetic resonance fingerprinting aided by deep learning.
  Or Perlman, Hirotaka Ito, Kai Herz, Naoyuki Shono, Hiroshi Nakashima, Moritz Zaiss, E. Antonio Chiocca, O Cohen, Matthew S. Rosen, Christian T. Farrar> ;Nature Biomedical Engineering. 2021 Nov 11
• 47 citations
  An oncolytic virus expressing a full-length antibody enhances antitumor innate immune response to glioblastoma.
  Bo Xu, Lei Tian, Jing Chen, Jing Wang, Rui Ma, Wenjuan Dong, Aimin Li, Jianying Zhang, E. Antonio Chiocca, Balveen Kaur, Mingye Feng, Michael A. Caligiuri, Jianhua Yu> ;Nature Communications. 2021 Oct 8
• 71 citations
  Glial and myeloid heterogeneity in the brain tumour microenvironment.
  Brian M Andersen, Camilo Faust Akl, Michael A. Wheeler, E. Antonio Chiocca, David A. Reardon, Francisco J. Quintana> ;Nature Reviews. Cancer. 2021 Sep 28
• 1 citations
  The Evolving Role of Neurosurgical Intervention for Central Nervous System Tumors.
  Pierpaolo Peruzzi, Pablo Q. Valdes, Manish K. Aghi, Mitchel S. Berger, Ennio Antonio Chiocca, Alexandra J. Golby> ;Hematology/oncology Clinics of North America. 2022 Feb 1
• 2 citations
  Treatment of glioblastoma with current oHSV variants reveals differences in efficacy and immune cell recruitment.
  Joseph W. Jackson, Bonnie Hall, Marco Marzulli, Vrusha K. Shah, Lisa Bailey, E. Antonio Chiocca, William F. Goins, Gary Kohanbash, Justus B. Cohen, Joseph C. Glorioso> ;Molecular Therapy Oncolytics. 2021 Jul 29
• 2 citations
  Evolution of the Neurosurgeon's Role in Clinical Trials for Glioblastoma: A Systematic Overview of the Clinicaltrials.Gov Database.
  Alireza Mansouri, Michelle E Beyn, Aditya Pancholi, Clement T. Chow, Ryan Wang, Alexandre Boutet, Gavin J B Elias, Jürgen Germann, Aaron Loh, Mathew R. Voisin, Andres ...> ;Neurosurgery. 2021 Jul 15
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Lectures

• Original Articles Anticancer Activity of Osmium(VI) Nitrido Complexes in Patient-Derived Glioblastoma Initiating Cells and in Vivo Mouse Models 
  2019 ASCO Annual Meeting - 6/1/2019