EricPerkeyMDPhD

PubMed

• 2 citations
  Stromal Notch ligands foster lymphopenia-driven functional plasticity and homeostatic proliferation of naive B cells.
  Daniela Gómez Atria, Brian T Gaudette, Jennifer Londregan, Samantha Kelly, Eric Perkey, Anneka Allman, Bhaskar Srivastava, Ute Koch, Freddy Radtke, Burkhard Ludewig, C...> ;The Journal of Clinical Investigation. 2022 Jul 1
• 2 citations
  Differential impact of a dyskeratosis congenita mutation in TPP1 on mouse hematopoiesis and germline.
  , , , , , , , , , , , , , , , , , , > ;Life Science Alliance. 2022 Jan 1
• 19 citations
  Acetylcholine-synthesizing macrophages in subcutaneous fat are regulated by β2 -adrenergic signaling.
  Alexander J. Knights, Shanshan Liu, Yingxu Ma, Victoria S Nudell, Eric Perkey, Matthew J. Sorensen, Robert T. Kennedy, Ivan Maillard, Li Ye, Heejin Jun, Jun Wu> ;The EMBO Journal. 2021 Aug 30
• 1 citations
  A Murine Model of X-Linked Moesin-Associated Immunodeficiency (X-MAID) Reveals Defects in T Cell Homeostasis and Migration.
  Lyndsay Avery, Tanner F Robertson, Christine F Wu, Nathan H Roy, Samuel D Chauvin, Eric Perkey, Ashley Vanderbeck, Ivan Maillard, Janis K Burkhardt> ;Frontiers in Immunology. 2021 Jan 1
• 228 citations
  Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies
  Kevin R. Parker, Denis Migliorini, Eric Perkey, Kathryn E. Yost, Aparna Bhaduri, Puneet Bagga, Mohammad Haris, Neil E. Wilson, Fang Liu, Khatuna Gabunia, John Scholler...> ;Cell. 2020 Oct 1
• 16 citations
  GCNT1-mediated O-glycosylation of the sialomucin CD43 is a sensitive indicator of notch signaling in activated T cells
  Eric Perkey, Dave Maurice De Sousa, Leolene J Carrington, Jooho Chung, Alexander Dils, David Granadier, Ute Koch, Freddy Radtke, Burkhard Ludewig, Bruce R. Blazar, Chr...> ;Journal of Immunology. 2020 Mar 15
• 112 citations
  Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia
  Szymon Klossowski, Hongzhi Miao, Katarzyna Kempińska, Tao Wu, Trupta Purohit, EunGi Kim, Brian M. Linhares, Dong Chen, Gloria Jih, Eric Perkey, Huang Huang, Miao He, B...> ;The Journal of Clinical Investigation. 2020 Feb 3
• 9 citations
  Early Notch Signals Induce a Pathogenic Molecular Signature during Priming of Alloantigen-Specific Conventional CD4+ T Cells in Graft-versus-Host Disease.
  Jooho Chung, Vedran Radojcic, Eric Perkey, Timothy J. Parnell, Yashar S. Niknafs, Xi Jin, Ann Friedman, Nathalie Labrecque, Bruce R. Blazar, Todd V. Brennan, Christian...> ;Journal of Immunology. 2019 Jul 15
• 26 citations
  Notch signaling mediated by Delta-like ligands 1 and 4 controls the pathogenesis of chronic GVHD in mice
  Vedran Radojcic, Katelyn Paz, Jooho Chung, Jing Du, Eric Perkey, Ryan Flynn, Sanja Ivčević, Michael Zaiken, Ann Friedman, Minhong Yan, Maria A. Pletneva, Stefanie Sara...> ;Blood. 2018 Nov 15
• 58 citations
  An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling.
  Heejin Jun, Hui Yu, Jianke Gong, Juan Jiang, Xiaona Qiao, Eric Perkey, Dong-Il Kim, Margo P. Emont, Alexander G. Zestos, Jung Sun Cho, Jianfeng Liu, Robert T. Kennedy,...> ;Nature Medicine. 2018 May 21
• 43 citations
  New Insights into Graft-Versus-Host Disease and Graft Rejection
  Eric Perkey, Ivan Maillard> ;Annual Review of Pathology. 2018 Jan 24
• 61 citations
  Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands
  Jooho Chung, Christen L. Ebens, Eric Perkey, Vedran Radojcic, Ute Koch, Leonardo Scarpellino, Alexander Tong, Frederick Allen, Sherri C. Wood, Jiane Feng, Ann Friedman...> ;The Journal of Clinical Investigation. 2017 Apr 3
• 34 citations
  BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells
  Ester Valls, Camille Lobry, Huimin Geng, Ling Wang, Mariano G. Cardenas, Martín A. Rivas, Leandro Cerchietti, Philmo Oh, Shao Ning Yang, Erin Oswald, Camille W. Graham...> ;Cancer Discovery. 2017 May 1
• 14 citations
  Increased Mammalian Target of Rapamycin Complex 2 Signaling Promotes Age-Related Decline in CD4 T Cell Signaling and Function
  Eric Perkey, Diane C. Fingar, Richard A. Miller, Gonzalo G. Garcia> ;Journal of Immunology. 2013 Nov 1
• 9 citations
  Ex vivo enzymatic treatment of aged CD4 T cells restores cognate T cell helper function and enhances antibody production in mice.
  Eric Perkey, Richard A. Miller, Gonzalo G. Garcia> ;Journal of Immunology. 2012 Dec 15
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Journal Articles

• Notch Signaling Mediated by Delta-like1/4 Ligands Controls the Pathogenesis of Chronic Graft-Versus-Host Disease in Mice  
  Ivan Maillard, Eric T Perkey, Maria A Pletneva, Stefanie Sarantopoulos, Bruce R Blazar, Vedran Radojcic, Blood