EstelleS.HarrisMD

Pulmonology • Salt Lake City, UT

Critical Care Medicine, Pleural Disease

Associate Professor of Medicine Co-Director Medical ICU

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Office
50 N Medical Dr
Salt Lake City, UT 84132
Phone+1 801-581-7806
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Education & Training

University of Michigan Health SystemFellowship, Pulmonary Disease and Critical Care Medicine, 1991 - 1994
Boston University Medical CenterResidency, Internal Medicine, 1988 - 1991
University of Colorado School of Medicine Anschutz Medical CampusClass of 1988

Certifications & Licensure

UT State Medical License 1996 - 2026
MI State Medical License 1991 - 1998
American Board of Internal Medicine Critical Care Medicine
American Board of Internal Medicine Pulmonary Disease

Clinical Trials

Efficacy and Safety of Emapalumab and Anakinra in Reducing Hyperinflammation and Respiratory Distress in Patients With COVID-19 Infection. Start of enrollment: 2020 Apr 02
Terminated
Phase 2, Phase 3

Publications & Presentations

PubMed

1 citations
Intravenous aviptadil and remdesivir for treatment of COVID-19-associated hypoxaemic respiratory failure in the USA (TESICO): a randomised, placebo-controlled trial.
Samuel M Brown, Christina E Barkauskas, Birgit Grund, Shweta Sharma, Andrew N Phillips, Lindsay Leither, Ithan D Peltan, Michael Lanspa, Daniel L Gilstrap, Ahmad Moura...> ;The Lancet. Respiratory Medicine. 2023 Sep 1
4 citations
Inhaled Sargramostim (Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor) for COVID-19-Associated Acute Hypoxemia: Results of the Phase 2, Randomized, ...
Robert Paine, Robert Chasse, E Scott Halstead, Jay Nfonoyim, David J Park, Timothy Byun, Bela Patel, Guido Molina-Pallete, Estelle S Harris, Fiona Garner, Lorinda Simm...> ;Military Medicine. 2022 Dec 2
15 citations
Neutralizing COVID-19 Convalescent Plasma in Adults Hospitalized With COVID-19: A Blinded, Randomized, Placebo-Controlled Trial.
Wesley H Self, Allison P Wheeler, Thomas G Stewart, Harry Schrager, Jason Mallada, Christopher B Thomas, Vince D Cataldo, Hollis R O'Neal Jr, Nathan I Shapiro, Conor H...> ;Chest. 2022 Nov 1
44 citations
Responses to a Neutralizing Monoclonal Antibody for Hospitalized Patients With COVID-19 According to Baseline Antibody and Antigen Levels : A Randomized Controlled Trial.
, Lundgren, J., Grund, B., Barkauskas, C., Holland, T., Gottlieb, R., Sandkovsky, U., Brown, S., Knowlton, K., Self, W., Files, D., Jain, M., Benfield, T., Bowdish, M....> ;Annals of Internal Medicine. 2022 Feb 1
29 citations
Variation in Early Management Practices in Moderate-to-Severe ARDS in the United States: The Severe ARDS: Generating Evidence Study
Nida Qadir, Raquel R. Bartz, Mary Cooter, Catherine L. Hough, Michael J. Lanspa, Valerie Banner-Goodspeed, Jen-Ting Chen, Shewit P. Giovanni, Dina Gomaa, Michael W. Sj...> ;Chest. 2021 Oct 1
6 citations
Passive Immunity Trial for Our Nation (PassITON): study protocol for a randomized placebo-control clinical trial evaluating COVID-19 convalescent plasma in hospitalize...
Wesley H. Self, Thomas G. Stewart, Allison P. Wheeler, Wissam El Atrouni, Amanda J. Bistran-Hall, Jonathan D Casey, Vince D. Cataldo, James D. Chappell, Claudia S. Coh...> ;Trials. 2021 Mar 20
275 citations
A Neutralizing Monoclonal Antibody for Hospitalized Patients with Covid-19.
, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;The New England Journal of Medicine. 2021 Mar 11
10 citations
Passive Immunity Trial for Our Nation (PassITON): study protocol for a randomized placebo-control clinical trial evaluating COVID-19 convalescent plasma in hospitalize...
Wesley H. Self, Thomas G. Stewart, Allison P. Wheeler, Wissam El Atrouni, Amanda J. Bistran-Hall, Jonathan D Casey, Vince D. Cataldo, James D. Chappell, Claudia S. Coh...> ;Research Square. 2021 Mar 2
21 citations
Hydroxychloroquine vs. Azithromycin for Hospitalized Patients with COVID-19 (HAHPS): Results of a Randomized, Active Comparator Trial.
Samuel M. Brown, Ithan D. Peltan, Naresh Kumar, Lindsay M. Leither, Brandon J. Webb, Nathan Starr, Colin K. Grissom, Whitney R. Buckel, Rajendu Srivastava, Allison M. ...> ;Annals of the American Thoracic Society. 2021 Apr 1
891 citations
Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome.
Elizabeth A. Middleton, Xue-Yan He, Frederik Denorme, Robert A. Campbell, David Ng, Steven P. Salvatore, Maria Mostyka, Amelia Baxter-Stoltzfus, Alain C. Borczuk, Mass...> ;Blood. 2020 Sep 3
24 citations
Hydroxychloroquine versus Azithromycin for Hospitalized Patients with Suspected or Confirmed COVID-19 (HAHPS). Protocol for a Pragmatic, Open-Label, Active Comparator ...
Samuel M. Brown, Ithan D. Peltan, Brandon J. Webb, Naresh Kumar, Nathan Starr, Colin K. Grissom, Whitney R. Buckel, Raj Srivastava, Estelle S. Harris, Lindsay M. Leith...> ;Annals of the American Thoracic Society. 2020 Jul 31
94 citations
Sepsis alters the transcriptional and translational landscape of human and murine platelets
Elizabeth A. Middleton, Jesse W. Rowley, Robert A. Campbell, Colin K. Grissom, Samuel M. Brown, Sarah J. Beesley, Hansjörg Schwertz, Yasuhiro Kosaka, Bhanu Kanth Manne...> ;Blood. 2019 Sep 19
48 citations
Microcirculatory perfusion disturbances in septic shock: results from the ProCESS trial
Michael J. Massey, Peter C. Hou, Michael R. Filbin, Henry E. Wang, Long Ngo, David T. Huang, William C. Aird, Victor Novack, Stephen Trzeciak, Donald M. Yealy, John A....> ;Critical Care. 2018 Nov 20
97 citations
Neonatal NET-inhibitory factor and related peptides inhibit neutrophil extracellular trap formation
Christian C. Yost, Hansjörg Schwertz, Mark J. Cody, Jared Wallace, Robert A. Campbell, Adriana Vieira-de-Abreu, Claudia V. Araujo, Sebastian Schubert, Estelle S. Harri...> ;The Journal of Clinical Investigation. 2016 Oct 3
54 citations
Platelet–Monocyte Aggregate Formation and Mortality Risk in Older Patients With Severe Sepsis and Septic Shock
Matthew T. Rondina, McKenzie Carlisle, Tamra Fraughton, Samuel M. Brown, Russell R. Miller, Estelle S. Harris, Andrew S. Weyrich, Guy A. Zimmerman, Mark A. Supiano, Co...> ;The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 2015 Feb 1
23 citations
Integrin αDβ2 (CD11d/CD18) is expressed by human circulating and tissue myeloid leukocytes and mediates inflammatory signaling.
Yasunari Miyazaki, Adriana Vieira-de-Abreu, Estelle S. Harris, Amrapali M. Shah, Andrew S. Weyrich, Hugo C. Castro-Faria-Neto, Guy A. Zimmerman> ;Plos One. 2014 Nov 21
67 citations
Lessons from rare maladies: leukocyte adhesion deficiency syndromes.
Estelle S. Harris, Andrew S. Weyrich, Guy A. Zimmerman> ;Current Opinion in Hematology. 2012 Dec 1
89 citations
In Vivo Platelet Activation in Critically Ill Patients With Primary 2009 Influenza A(H1N1)
Matthew T. Rondina, BreAnna Brewster, Colin K. Grissom, Guy A. Zimmerman, Diana Kastendieck, Estelle S. Harris, Andrew S. Weyrich> ;Chest. 2012 Jun 1
16 citations
Whole blood flow cytometry measurements of in vivo platelet activation in critically-Ill patients are influenced by variability in blood sampling techniques.
Matthew T. Rondina, Colin K. Grissom, Shaohua Men, Estelle S. Harris, Hansjörg Schwertz, Guy A. Zimmerman, Andrew S. Weyrich> ;Thrombosis Research. 2012 Jun 1
15 citations
Leukocyte Adhesion Deficiency-I variant Syndrome (LAD-Iv, LAD-III): Molecular Characterization of the Defect in an Index Family
Estelle S. Harris, Tammy L. Smith, Gregory M. Springett, Andrew S. Weyrich, Guy A. Zimmerman> ;American Journal of Hematology. 2012 Mar 1
111 citations
The septic milieu triggers expression of spliced tissue factor mRNA in human platelets
Matthew T. Rondina, Hansjörg Schwertz, Estelle S. Harris, Bjoern F. Kraemer, Robert A. Campbell, Nigel Mackman, Colin K. Grissom, Andrew S. Weyrich, Guy A. Zimmerman> ;Journal of Thrombosis and Haemostasis. 2011 Apr 1
231 citations
Impaired neutrophil extracellular trap (NET) formation: a novel innate immune deficiency of human neonates
Christian C. Yost, Mark J. Cody, Estelle S. Harris, Nathan L. Thornton, Alison M. McInturff, Mark L. Martinez, Nancy B. Chandler, Christopher K. Rodesch, Kurt H. Alber...> ;Blood. 2009 Jun 18
19 citations
Integrin αDβ2 Is Dynamically Expressed by Inflamed Macrophages and Alters the Natural History of Lethal Systemic Infections
Yasunari Miyazaki, Michaeline Bunting, Diana M. Stafforini, Estelle S. Harris, Thomas M. McIntyre, Stephen M. Prescott, Valber da Silva Frutuoso, Fábio Coelho Amendoei...> ;Journal of Immunology. 2008 Jan 1
120 citations
Leukocyte adhesion deficiency syndromes: Adhesion and tethering defects involving β2 integrins and selectin ligands
Michaeline Bunting, Estelle S. Harris, Thomas M. McIntyre, Stephen M. Prescott, Guy A. Zimmerman> ;Current Opinion in Hematology. 2002 Jan 1
80 citations
Differential regulation of matrix metalloproteinase-9 by monocytes adherent to collagen and platelets.
Spencer W. Galt, Stephan Lindemann, Don Medd, Loren L. Allen, Larry W. Kraiss, Estelle S. Harris, Stephen M. Prescott, Thomas M. McIntyre, Andrew S. Weyrich, Guy A. Zi...> ;Circulation Research. 2001 Sep 14
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Press Mentions

Hospitals in Rocky Mountain States Struggling to Keep up with Coronavirus SurgeOctober 28th, 2020
Latest Booster Reduces Adults’ Risk of Moderate or Severe COVID by More Than HalfMarch 3rd, 2024