EstherHsuan-HsinChangMD

Obstetrics & Gynecology • San Francisco, CA

Physician

Join to view full profile

Dr. Chang is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

Connect with other colleagues in the same hospital or clinic
Search all U.S. specialist profiles and refer a patient
Read the latest clinical news and earn CME/CEU credits

See Dr. Chang's full profile

Already have an account?

Office
1520 stockton street
San Francisco, CA 94133
Phone+1 415-391-9686
Is this information wrong?

Education & Training

Kern Medical CenterResidency, Obstetrics and Gynecology, 1995 - 1999
Sidney Kimmel Medical College at Thomas Jefferson UniversityClass of 1995

Certifications & Licensure

CA State Medical License 1997 - 2024
NY State Medical License 2004 - 2013
PA State Medical License 2000 - 2004
American Board of Obstetrics and Gynecology Obstetrics & Gynecology

Awards, Honors, & Recognition

Fellow (FACOG) American Congress of Obstetricians and Gynecologists

Publications & Presentations

PubMed

42 citations
A tumor-targeting nanomedicine carrying the p53 gene crosses the blood–brain barrier and enhances anti-PD-1 immunotherapy in mouse models of glioblastoma
Sang-Soo Kim, Joe B. Harford, Manish Moghe, Tiffani Slaughter, Caroline Doherty, Esther H. Chang> ;International Journal of Cancer. 2019 Nov 1
11 citations
Activating p53 family member TAp63: A novel therapeutic strategy for targeting p53-altered tumors.
Preethi H. Gunaratne, Yinghong Pan, Abhi K. Rao, Chunru Lin, Anadulce Hernandez-Herrera, Ke Liang, Antonina Rait, Avinashnarayan Venkatanarayan, Ashley Benham, Farwah ...> ;Cancer. 2019 Jul 15
58 citations
Integrated Genomic and Functional microRNA Analysis Identifies miR-30-5p as a Tumor Suppressor and Potential Therapeutic Nanomedicine in Head and Neck Cancer
Anthony Saleh, Hui Cheng, Scott E. Martin, Han Si, Pinar Ormanoglu, Sophie Carlson, Paul E. Clavijo, Xinping Yang, Rita Das, Shaleeka Cornelius, Jamie Couper, Douglas ...> ;Clinical Cancer Research. 2019 May 1
31 citations
Combination with SGT-53 overcomes tumor resistance to a checkpoint inhibitor.
Sang-Soo Kim, Joe B. Harford, Manish Moghe, Antonina Rait, Esther H. Chang> ;Oncoimmunology. 2018 Aug 1
91 citations
Targeted nanocomplex carrying siRNA against MALAT1 sensitizes glioblastoma to temozolomide
Sang-Soo Kim, Joe B. Harford, Manish Moghe, Antonina Rait, Kathleen F. Pirollo, Esther H. Chang> ;Nucleic Acids Research. 2018 Feb 16
15 citations
Nanotherapeutics for Gene Modulation that Prevents Apoptosis in the Brain and Fatal Neuroinflammation.
Sang-Soo Kim, Antonina Rait, Emilio R. Garrido-Sanabria, Kathleen F. Pirollo, Joe B. Harford, Esther H. Chang> ;Molecular Therapy. 2018 Jan 3
24 citations
Nanocomplex-based TP53 gene therapy promotes anti-tumor immunity through TP53- and STING-dependent mechanisms.
Ellen C. Moore, Lillian Sun, Paul E. Clavijo, Jay Friedman, Joe B. Harford, Anthony Saleh, Carter Van Waes, Esther H. Chang, Clint T. Allen> ;Oncoimmunology. 2017 Nov 28
66 citations
Safety and Efficacy in Advanced Solid Tumors of a Targeted Nanocomplex Carrying the p53 Gene Used in Combination with Docetaxel: A Phase 1b Study.
Kathleen F. Pirollo, John Nemunaitis, Po Ki Leung, Robert Nunan, Jana Adams, Esther H. Chang> ;Molecular Therapy. 2016 Sep 1
35 citations
A Phase l Study of a Tumor-targeted Systemic Nanodelivery System, SGT-94, in Genitourinary Cancers.
Arlene O. Siefker-Radtke, Xin Qiao Zhang, Charles C. Guo, Yu Shen, Kathleen F. Pirollo, Sharjeel H. Sabir, Chris P. Leung, Cindy Leong-Wu, Chi Ming Ling, Esther H. Cha...> ;Molecular Therapy. 2016 Aug 1
89 citations
Effective treatment of glioblastoma requires crossing the blood–brain barrier and targeting tumors including cancer stem cells: The promise of nanomedicine
Sang-Soo Kim, Joe B. Harford, Kathleen F. Pirollo, Esther H. Chang> ;Biochemical and Biophysical Research Communications. 2015 Dec 18
69 citations
Nanomedicine: Past, present and future – A global perspective
Esther H. Chang, Joe B. Harford, Michael A.W. Eaton, Patrick M. Boisseau, Admire Dube, Rose Hayeshi, Hulda Swai, Dong Soo Lee> ;Biochemical and Biophysical Research Communications. 2015 Dec 18
67 citations
Encapsulation of temozolomide in a tumor-targeting nanocomplex enhances anti-cancer efficacy and reduces toxicity in a mouse model of glioblastoma.
Sang-Soo Kim, Antonina Rait, Eric Kim, James DeMarco, Kathleen F. Pirollo, Esther H. Chang> ;Cancer Letters. 2015 Dec 1
17 citations
Isolation and Culturing of Glioma Cancer Stem Cells
Sang-Soo Kim, Kathleen F. Pirollo, Esther H. Chang> ;Current Protocols in Cell Biology. 2015 Jun 1
70 citations
A Tumor-targeting p53 Nanodelivery System Limits Chemoresistance to Temozolomide Prolonging Survival in a Mouse Model of Glioblastoma Multiforme
Sang-Soo Kim, Antonina Rait, Eric Kim, Kathleen F. Pirollo, Esther H. Chang> ;Nanomedicine. 2015 Feb 1
100 citations
A nanoparticle carrying the p53 gene targets tumors including cancer stem cells, sensitizes glioblastoma to chemotherapy and improves survival.
Sang-Soo Kim, Antonina Rait, Eric Kim, Kathleen F. Pirollo, Maki Nishida, Natalia Farkas, John A. Dagata, Esther H. Chang> ;ACS Nano. 2014 May 15
21 citations
Hepatitis C virus clearance correlates with HLA-DR expression on proliferating CD8+ T cells in immune-primed chimpanzees.
Iryna Zubkova, Hongying Duan, Frances Wells, Howard Mostowski, Esther H. Chang, Kathleen F. Pirollo, Kris Krawczynski, Robert E. Lanford, Marian E. Major> ;Hepatology. 2014 Mar 1
37 citations
The Clinical Potential of Targeted Nanomedicine: Delivering to Cancer Stem-like Cells
Sang-Soo Kim, Antonina Rait, Farwah Rubab, Abhi K. Rao, Michael C Kiritsy, Kathleen F. Pirollo, Shangzi Wang, Louis M. Weiner, Esther H. Chang> ;Molecular Therapy. 2014 Feb 1
33 citations
Assessing the barriers to image-guided drug delivery
Gregory M. Lanza, Chrit T. W. Moonen, James R. Baker, Esther H. Chang, Zheng Cheng, Piotr Grodzinski, Katherine W. Ferrara, Kullervo Hynynen, Gary J. Kelloff, Yong Eun...> ;Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. 2014 Jan 1
160 citations
Phase I study of a systemically delivered p53 nanoparticle in advanced solid tumors.
Neil Senzer, John Nemunaitis, Derek Nemunaitis, Cynthia Bedell, Gerald Edelman, Minal A. Barve, Robert Nunan, Kathleen F. Pirollo, Antonina Rait, Esther H. Chang> ;Molecular Therapy. 2013 May 1
75 citations
Transferrin receptor targeting nanomedicine delivering wild-type p53 gene sensitizes pancreatic cancer to gemcitabine therapy
E.R. Camp, Cindy Wang, Elizabeth C. Little, Patricia M. Watson, Kathleen F. Pirollo, Antonina Rait, David J. Cole, Esther H. Chang, Dennis K. Watson> ;Cancer Gene Therapy. 2013 Mar 8
17 citations
Nanodelivery of MRI Contrast Agent Enhances Sensitivity of Detection of Lung Cancer Metastases
Matthew L. Freedman, Esther H. Chang, Qi Zhou, Kathleen F. Pirollo> ;Academic Radiology. 2009 May 1
26 citations
T-cell vaccines that elicit effective immune responses against HCV in chimpanzees may create greater immune pressure for viral mutation.
Iryna Zubkova, Y.H. Choi, Esther H. Chang, Kathleen F. Pirollo, T. Uren, Hisayoshi Watanabe, Frances Wells, Alla Kachko, Kris Krawczynski, Marian E. Major> ;Vaccine. 2009 Apr 28
35 citations
Nanoimmunoliposome Delivery of Superparamagnetic Iron Oxide Markedly Enhances Targeting and Uptake in Human Cancer Cells In Vitro and In Vivo
Chengli Yang, Antonina Rait, Kathleen F. Pirollo, John A. Dagata, Natalia Farkas, Esther H. Chang> ;Nanomedicine. 2008 Dec 1
238 citations
Does a targeting ligand influence nanoparticle tumor localization or uptake
Kathleen F. Pirollo, Esther H. Chang> ;Trends in Biotechnology. 2008 Oct 1
5 citations
Physical characterization methods for iron oxide contrast agents encapsulated within a targeted liposome-based delivery system
John A. Dagata, Natalia Farkas, Cindi L. Dennis, Robert D. Shull, Vincent A. Hackley, C Yang, Kathleen F. Pirollo, Esther H. Chang> ;Nanotechnology. 2008 Jul 30
Join now to see all

Grant Support

Nanoimmunoliposome-Complexed Spio: Tumor-Specific Detection Of Early Lung CancerNational Cancer Institute2008–2010
A Tumor-Specific Nanoimmunocomplex Markedly Improves MR ImagingNational Cancer Institute2006
A Dual Molecular/Tumor Targeting Therapy For PancaNational Cancer Institute2004–2005
Enhancement Of Tumor-Targeted Transgene ExpressionNational Cancer Institute2004
A Dual Molecular/Targeting Therapy For PancaNational Cancer Institute2003
Immunoliposome-Mediated Gene Therapy For Prostate CancerNational Cancer Institute2002–2003
Targeting Stealth Liposome For Cancer Gene TherapyNational Cancer Institute2002
A Novel Improvement On Radiotherapy For ScchnNational Institute Of Dental &Craniofacial Research1999–2002
Immunoliposome Mediated Gene Therapy For Prostate CancerNational Cancer Institute1999
Status Of P53 In A Lfs Cancer Prone FamilyNational Cancer Institute1997–1999
Status Of P53 In A Lfs Cancer Prone FamilyNational Cancer Institute1995–1996
Oncogenes In Human Cancer InductionNational Cancer Institute1994
Oncogenes In Human Cancer InductionNational Cancer Institute1986–1994
Small Instrumentation ProgramNational Institute Of Allergy And Infectious Diseases1988
Oncogenes (C-Ras) In Human Cancer InductionNational Cancer Institute1985

Other Languages

Chinese (Mandarin), Chinese (Cantonese)

EstherHsuan-HsinChangMD

Dr. Chang is on Doximity

Education & Training

Certifications & Licensure

Awards, Honors, & Recognition

Publications & Presentations

Grant Support

Other Languages

Viewing the full profile is available to verified healthcare professionals only.