FabianBockMD

PubMed

• Rac1 promotes kidney collecting duct repair by mechanically coupling cell morphology to mitotic entry.
  Bock, F., Dong, X., Li, S., Viquez, O., Sha, E., Tantengco, M., Hennen, E., Plosa, E., Ramezani, A., Brown, K., Whang, Y., Terker, A., Arroyo, J., Harrison, D., Fogo, ...> ;Science Advances. 2024 Feb 9
• Angiotensin II acts through Rac1 to upregulate pendrin: role of NADPH oxidase.
  Truyen D Pham, Jill W Verlander, Chao Chen, Vladimir Pech, Hailey I Kim, Young Hee Kim, I David Weiner, Ginger L Milne, Roy Zent, Fabian Bock, Dennis Brown, Amity Eato...> ;American Journal of Physiology. Renal Physiology. 2024 Feb 1
• Does it matter how we measure urinary creatinine in patients taking SGLT2 inhibitors?
  Isermann, B., Bock, F.> ;Nephrology, Dialysis, Transplantation. 2024 Jan 13
• 2 citations
  Alveolar repair following LPS-induced injury requires cell-ECM interactions.
  Jennifer Ms Sucre, Fabian Bock, Nicholas M Negretti, John T Benjamin, Peter M Gulleman, Xinyu Dong, Kimberly T Ferguson, Christopher S Jetter, Wei Han, Yang Liu, Seung...> ;JCI Insight. 2023 Jul 24
• High sodium intake does not worsen low potassium-induced kidney damage.
  Yahua Zhang, Juan Pablo Arroyo, Fabian Bock, Ming-Zhi Zhang, Raymond C Harris, Andrew S Terker> ;Physiological Reports. 2023 Apr 1
• Insulin-regulated aminopeptidase is required for water excretion in response to acute hypotonic stress.
  Yvonne Zuchowski, Joshua Carty, Andrew S Terker, Fabian Bock, Jonathan B Trapani, Gautam Bhave, Jason A Watts, Susanna Keller, Mingzhi Zhang, Roy Zent, Raymond C Harri...> ;American Journal of Physiology. Renal Physiology. 2023 Jun 1
• 2 citations
  Kidney collecting duct cells make vasopressin in response to NaCl-induced hypertonicity.
  Juan Pablo Arroyo, Andrew S Terker, Yvonne Zuchowski, Jason A Watts, Fabian Bock, Cameron Meyer, Wentian Luo, Meghan E Kapp, Edward R Gould, Adam X Miranda, Joshua Car...> ;JCI Insight. 2022 Dec 22
• 6 citations
  Ligand-independent integrin β1 signaling supports lung adenocarcinoma development.
  Scott M Haake, Erin J Plosa, Jonathan A Kropski, Lindsay A Venton, Anupama Reddy, Fabian Bock, Betty T Chang, Allen J Luna, Kateryna Nabukhotna, Zhi-Qi Xu, Rebecca A P...> ;JCI Insight. 2022 Aug 8
• 2 citations
  The laminin-binding integrins regulate nuclear factor kappa-β-dependent epithelial cell polarity and inflammation.
  Eugenia M. Yazlovitskaya, Erin J. Plosa, Fabian Bock, Olga M. Viquez, Glenda Mernaugh, Leslie Gewin, Adèle De Arcangelis, Elisabeth Georges-Labouesse, Arnoud Sonnenber...> ;Journal of Cell Science. 2021 Nov 29
• 4 citations
  Rac1 promotes kidney collecting duct integrity by limiting actomyosin activity.
  Fabian Bock, Bertha C Elias, Xinyu Dong, Diptiben V. Parekh, Glenda Mernaugh, Olga M. Viquez, Anjana Hassan, Venkateswara Rao Amara, Jiageng Liu, Kyle L. Brown, Andrew...> ;The Journal of Cell Biology. 2021 Nov 1
• 21 citations
  Different DOACs Control Inflammation in Cardiac Ischemia-Reperfusion Differently.
  Ihsan Gadi, Sameen Fatima, Ahmed Elwakiel, Sumra Nazir, Moh'd Mohanad Al-Dabet, Rajiv Rana, Fabian Bock, Jayakumar Manoharan, Dheerendra Gupta, Ronald Biemann, Bernhar...> ;Circulation Research. 2021 Feb 19
• 15 citations
  Racial disparities in end-stage renal disease in a high-risk population: the Southern Community Cohort Study
  Fabian Bock, Thomas G. Stewart, Cassianne Robinson-Cohen, Jennifer Morse, Edmond K. Kabagambe, Kerri L. Cavanaugh, Kelly A. Birdwell, Adriana M. Hung, Khaled Abdel-Kad...> ;BMC Nephrology. 2019 Aug 7
• 26 citations
  Activated protein C reverses epigenetically sustained p66 Shc expression in plaque-associated macrophages in diabetes.
  Khurrum Shahzad, Ihsan Gadi, Sumra Nazir, Moh'd Mohanad Al-Dabet, Shrey Kohli, Fabian Bock, Lukas Breitenstein, Satish Ranjan, Tina Fuchs, Zuhir Halloul, Peter P. Nawr...> ;Communications Biology. 2018 Aug 6
• Production of [Formula: see text] and [Formula: see text] in p-Pb collisions at [Formula: see text] TeV.
  Adamová, D.,Aggarwal, M. M.,Aglieri Rinella, G.,Agnello, M.,Agrawal, N.,Ahammed, Z.,Ahmad, S.,Ahn, S. U.,Aiola, S.,Akindinov, A.,Alam, S. N.,Albuquerque, DSD.,Aleksand...> ;Eur Phys J C Part Fields. 2018 Feb 13
• 119 citations
  Cytoprotective activated protein C averts Nlrp3 inflammasome–induced ischemia-reperfusion injury via mTORC1 inhibition
  Sumra Nazir, Ihsan Gadi, Moh'd Mohanad Al-Dabet, Ahmed Elwakiel, Shrey Kohli, Sanchita Ghosh, Jayakumar Manoharan, Satish Ranjan, Fabian Bock, Ruediger C. Braun-Dullae...> ;Blood. 2017 Dec 14
• 45 citations
  Farnesoid X Receptor Agonism Protects against Diabetic Tubulopathy: Potential Add-On Therapy for Diabetic Nephropathy
  Andi Marquardt, Moh'd Mohanad Al-Dabet, Sanchita Ghosh, Shrey Kohli, Jayakumar Manoharan, Ahmed Elwakiel, Ihsan Gadi, Fabian Bock, Sumra Nazir, Hongjie Wang, Jonathan ...> ;Journal of the American Society of Nephrology. 2017 Nov 1
• 26 citations
  Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function.
  Thati Madhusudhan, Hongjie Wang, Sanchita Ghosh, Wei Dong, Varun Kumar, Moh'd Mohanad Al-Dabet, Jayakumar Manoharan, Sumra Nazir, Ahmed Elwakiel, Fabian Bock, Shrey Ko...> ;Blood. 2017 Sep 21
• 30 citations
  Activated protein C protects from GvHD via PAR2/PAR3 signalling in regulatory T-cells.
  Satish Ranjan, Alexander Goihl, Shrey Kohli, Ihsan Gadi, Mandy Pierau, Khurrum Shahzad, Dheerendra Gupta, Fabian Bock, Hongjie Wang, Haroon Shaikh, Thilo Kähne, Dirk R...> ;Nature Communications. 2017 Aug 21
• 23 citations
  Thrombomodulin-dependent protein C activation is required for mitochondrial function and myelination in the central nervous system.
  Juliane Wolter, Lorenz Schild, Fabian Bock, Andrea Hellwig, Ihsan Gadi, Moh′d Mohanad Al‐Dabet, Satish Ranjan, Raik Rönicke, Peter P. Nawroth, Karl‐Uwe Petersen, Chris...> ;Journal of Thrombosis and Haemostasis. 2016 Sep 1
• 118 citations
  Maternal extracellular vesicles and platelets promote preeclampsia via inflammasome activation in trophoblasts
  Shrey Kohli, Satish Ranjan, Juliane Hoffmann, Muhammed Kashif, Evelyn A. Daniel, Moh'd Mohanad Al-Dabet, Fabian Bock, Sumra Nazir, Hanna Huebner, Peter R. Mertens, Kla...> ;Blood. 2016 Oct 27
• 65 citations
  Stabilization of endogenous Nrf2 by minocycline protects against Nlrp3-inflammasome induced diabetic nephropathy.
  Khurrum Shahzad, Fabian Bock, Moh'd Mohanad Al-Dabet, Ihsan Gadi, Sumra Nazir, Hongjie Wang, Shrey Kohli, Satish Ranjan, Peter R. Mertens, Peter P. Nawroth, Berend Ise...> ;Scientific Reports. 2016 Oct 10
• 83 citations
  Caspase-1, but Not Caspase-3, Promotes Diabetic Nephropathy
  Khurrum Shahzad, Fabian Bock, Moh'd Mohanad Al-Dabet, Ihsan Gadi, Shrey Kohli, Sumra Nazir, Sanchita Ghosh, Satish Ranjan, Hongjie Wang, Thati Madhusudhan, Peter P. Na...> ;Journal of the American Society of Nephrology. 2016 Feb 1
• 62 citations
  Activated Protein C Ameliorates Renal Ischemia-Reperfusion Injury by Restricting Y-Box Binding Protein-1 Ubiquitination
  Wei Dong, Hongjie Wang, Khurrum Shahzad, Fabian Bock, Moh'd Mohanad Al-Dabet, Satish Ranjan, Juliane Wolter, Shrey Kohli, Juliane Hoffmann, Vishnu M. Dhople, Cheng Zhu...> ;Journal of the American Society of Nephrology. 2015 May 26
• 124 citations
  Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy
  Thati Madhusudhan, Hongjie Wang, Wei Dong, Sanchita Ghosh, Fabian Bock, Veera Raghavan Thangapandi, Satish Ranjan, Juliane Wolter, Shrey Kohli, Khurrum Shahzad, Floria...> ;Nature Communications. 2015 Mar 10
• 299 citations
  Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy.
  Khurrum Shahzad, Fabian Bock, Wei Dong, Hongjie Wang, Stefan Kopf, Shrey Kohli, Moh'd Mohanad Al-Dabet, Satish Ranjan, Juliane Wolter, Christian Wacker, Ronald Biemann...> ;Kidney International. 2015 Jan 1
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