FrancineEvalina(Garrett)Garrett-BakelmanMD

PubMed

• Acute myeloid leukemia stratifies as 2 clinically relevant sphingolipidomic subtypes.
  B Bishal Paudel, Su-Fern Tan, Todd E Fox, Johnson Ung, Upendarrao Golla, Jeremy J P Shaw, Wendy Dunton, Irene Lee, Wisam A Fares, Satyam Patel, Arati Sharma, Aaron D V...> ;Blood Advances. 2024 Mar 12
• Multi-ancestry epigenome-wide analyses identify methylated sites associated with aortic augmentation index in TOPMed MESA.
  Ani Manichaikul, Xiaowei Hu, Jeongok Logan, Younghoon Kwon, Joao Lima, David Jacobs, Daniel Duprez, Lyndia Brumback, Kent Taylor, Peter Durda, Craig Johnson, Elaine Co...> ;Research Square. 2023 Jul 13
• 1 citations
  Measurable residual disease by flow cytometry in acute myeloid leukemia is prognostic, independent of genomic profiling.
  Chezi Ganzel, Zhuoxin Sun, Timour Baslan, Yanming Zhang, Mithat Gönen, Omar I Abdel-Wahab, Janis Racevskis, Francine Garrett-Bakelman, Scott W Lowe, Hugo F Fernandez, ...> ;Leukemia Research. 2022 Dec 1
• 1 citations
  Integrative analysis identifies an older female-linked AML patient group with better risk in ECOG-ACRIN Cancer Research Group's clinical trial E3999.
  Franck Rapaport, Kenneth Seier, Yaseswini Neelamraju, Duane Hassane, Timour Baslan, Daniel T Gildea, Samuel Haddox, Tak Lee, H Moses Murdock, Caroline Sheridan, Alexis...> ;Blood Cancer Journal. 2022 Sep 23
• 7 citations
  Harnessing the power of sphingolipids: Prospects for acute myeloid leukemia.
  Johnson Ung, Su-Fern Tan, Todd E Fox, Jeremy J P Shaw, Luke R Vass, Pedro Costa-Pinheiro, Francine E Garrett-Bakelman, Michael K Keng, Arati Sharma, David F Claxton, R...> ;Blood Reviews. 2022 Sep 1
• 26 citations
  DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation.
  R N Batra, Aviezer Lifshitz, Ana Tufegdzic Vidakovic, Suet-Feung Chin, Ankita Sati-Batra, Stephen John Sammut, Elena Provenzano, H. Raza Ali, A. Dariush, Alejandra Bru...> ;Nature Communications. 2021 Sep 13
• 25 citations
  Frequent somatic TET2 mutations in chronic NK-LGL leukemia with distinct patterns of cytopenias
  Thomas L. Olson, Hee Jin Cheon, Jeffrey C. Xing, Kristine C. Olson, Umadevi Paila, Cait E. Hamele, Yaseswini Neelamraju, Bryna C. Shemo, Matt Schmachtenberg, Shriram K...> ;Blood. 2021 Aug 26
• 6 citations
  An Esrrb and Nanog Cell Fate Regulatory Module Controlled by Feed Forward Loop Interactions.
  Ana Sevilla, Dimitri Papatsenko, Amin R. Mazloom, Huilei Xu, Ana Vasileva, Richard D. Unwin, Gary LeRoy, Edward Y. Chen, Francine E. Garrett-Bakelman, Dung Fang Lee, B...> ;Frontiers in Cell and Developmental Biology. 2021 Mar 19
• 8 citations
  Genomic and evolutionary portraits of disease relapse in acute myeloid leukemia.
  Franck Rapaport, Yaseswini Neelamraju, Timour Baslan, Duane C. Hassane, Agata Gruszczynska, Marc Robert de Massy, Noushin Farnoud, Samuel Haddox, Tak C. Lee, Juan S. M...> ;Leukemia. 2021 Feb 12
• 100 citations
  Chemotherapy Induces Senescence-Like Resilient Cells Capable of Initiating AML Recurrence.
  Cihangir Duy, Meng Li, Matt Teater, Cem Meydan, Francine E. Garrett-Bakelman, Tak C. Lee, Christopher R. Chin, Ceyda Durmaz, Kimihito Cojin Kawabata, Eugen Dhimolea, C...> ;Cancer Discovery. 2021 Jan 26
• 35 citations
  Temporal Telomere and DNA Damage Responses in the Space Radiation Environment.
  Jared J. Luxton, Miles J. McKenna, Lynn Taylor, Kerry George, Sara R. Zwart, Brian Crucian, Viktor R. Drel, Francine E. Garrett-Bakelman, Matthew MacKay, Daniel Butler...> ;Cell Reports. 2020 Dec 8
• 21 citations
  Clonal Hematopoiesis Before, During, and After Human Spaceflight.
  Nuria Mencia-Trinchant, Matthew J MacKay, Christopher Chin, Ebrahim Afshinnekoo, Jonathan Foox, Cem Meydan, Daniel Butler, Christopher Mozsary, Nicholas A Vernice, Cha...> ;Cell Reports. 2020 Dec 8
• 26 citations
  Circulating miRNA Spaceflight Signature Reveals Targets for Countermeasure Development.
  Sherina Malkani, Christopher R. Chin, Egle Cekanaviciute, Marie Mortreux, Hazeem Okinula, Marcel Tarbier, Ann-Sofie Schreurs, Yasaman Shirazi-Fard, Candice Tahimic, De...> ;Cell Reports. 2020 Dec 8
• 27 citations
  Multi-omic, Single-Cell, and Biochemical Profiles of Astronauts Guide Pharmacological Strategies for Returning to Gravity.
  Monica L. Gertz, Christopher R. Chin, Delia Tomoiaga, Matthew MacKay, Christina Chang, Daniel Butler, Ebrahim Afshinnekoo, Daniela Bezdan, Michael A. Schmidt, Christop...> ;Cell Reports. 2020 Nov 25
• 3 citations
  Targeted detection and quantitation of histone modifications from 1,000 cells
  Nebiyu Abshiru, Jacek Sikora, Jeannie M. Camarillo, Juliette A. Morris, Philip D. Compton, Tak C. Lee, Yaseswini Neelamraju, Samuel Haddox, Caroline Sheridan, Martin C...> ;Plos One. 2020 Oct 26
• 7 citations
  COCOA: coordinate covariation analysis of epigenetic heterogeneity.
  John T. Lawson, Jason P. Smith, Stefan Bekiranov, Francine E. Garrett-Bakelman, Nathan C. Sheffield> ;Genome Biology. 2020 Sep 7
• 21 citations
  CD97 is a critical regulator of acute myeloid leukemia stem cell function.
  Gaëlle H. Martin, Nainita Roy, Sohini Chakraborty, Alexis Desrichard, Stephen S. Chung, Carolien M. Woolthuis, Wenhuo Hu, Iryna berezniuk, Francine E. Garrett-Bakelman...> ;The Journal of Experimental Medicine. 2019 Oct 7
• 31 citations
  Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML.
  Cihangir Duy, Matt Teater, Francine E. Garrett-Bakelman, Tak C. Lee, Cem Meydan, Jacob L. Glass, Meng Li, Johannes C. Hellmuth, Helai P. Mohammad, Kimberly N. Smithema...> ;Cancer Discovery. 2019 Jul 1
• 413 citations
  The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight.
  Francine E. Garrett-Bakelman, Manjula Darshi, Stefan J. Green, Ruben C. Gur, Ling Lin, Brandon R. Macias, Miles J. McKenna, Cem Meydan, Tejaswini Mishra, Jad Nasrini, ...> ;Science. 2019 Apr 12
• 62 citations
  Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity
  Hiroyoshi Kunimoto, Cem Meydan, Abbas Nazir, Justin T. Whitfield, Kaitlyn Shank, Franck Rapaport, Rebecca Maher, Elodie Pronier, Sara C. Meyer, Francine E. Garrett-Bak...> ;Cancer Cell. 2018 Jan 8
• 746 citations
  The N 6 -methyladenosine (m 6 A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells
  Ly P. Vu, Brian F. Pickering, Yuanming Cheng, Sara Zaccara, Diu T.T. Nguyen, Gerard Minuesa, Timothy Chou, Arthur Chow, Yogesh Saletore, Matthew MacKay, Jessica Schulm...> ;Nature Medicine. 2017 Sep 18
• 81 citations
  Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers
  Jacob L. Glass, Duane C. Hassane, Bas J. Wouters, Hiroyoshi Kunimoto, Roberto Avellino, Francine E. Garrett-Bakelman, Olga A. Guryanova, Robert L. Bowman, Shira Redlic...> ;Cancer Discovery. 2017 Aug 1
• 70 citations
  Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells
  Ly P. Vu, Camila Prieto, Elianna M. Amin, Sagar Chhangawala, Andrei V. Krivtsov, M. Nieves Calvo-Vidal, Timothy Chou, Arthur Chow, Gerard Minuesa, Sun Mi Park, Trevor ...> ;Nature Genetics. 2017 Apr 24
• 15 citations
  Aid is a key regulator of myeloid/erythroid differentiation and DNA methylation in hematopoietic stem/progenitor cells
  Hiroyoshi Kunimoto, Anna Sophia McKenney, Cem Meydan, Kaitlyn Shank, Abbas Nazir, Franck Rapaport, Benjamin H. Durham, Francine E. Garrett-Bakelman, Elodie Pronier, Al...> ;Blood. 2017 Mar 30
• 73 citations
  Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2- and TET2-Mutant Acute Myeloid Leukemia.
  Alan H. Shih, Cem Meydan, Kaitlyn Shank, Francine E. Garrett-Bakelman, Patrick S. Ward, Andrew M. Intlekofer, Abbas Nazir, Eytan M. Stein, Kristina M. Knapp, Jacob L. ...> ;Cancer Discovery. 2017 May 1
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Lectures

• Special Symposium on ASH-Supported Researchers 
  60th American Society of Hematology Annual Meeting - 12/3/2018
• Special Symposium on ASH-Supported Researchers 
  60th American Society of Hematology Annual Meeting - 12/1/2018