FrancisXDowneyMD

Thoracic Surgery • Phoenix, AZ

Adult Cardiac Surgery, Cardiovascular Surgery

Cardiothoracic Surgeon

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Office
5777 E. Mayo Boulevard
Phoenix, AZ 85050
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Education & Training

Loyola University Medical CenterFellowship, Thoracic Surgery, 1991 - 1993
Spectrum Health/Michigan State UniversityResidency, Surgery, 1986 - 1991
The University of Toledo College of MedicineClass of 1986

Certifications & Licensure

NM State Medical License 2023 - 2027
WI State Medical License 1993 - 2025
AK State Medical License 2023 - 2024
AZ State Medical License 2019 - 2024
IL State Medical License 1991 - 2002
MI State Medical License 1987 - 1994
American Board of Surgery Surgery
American Board of Thoracic Surgery Thoracic and Cardiac Surgery

Awards, Honors, & Recognition

Best Doctors 2015-2020
Top Doctors- M Magazine 2013
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013
Super Doctor SuperDoctors.com
Fellow (FACS) American College of Surgeons
Top MD Consumers Checkbook
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Clinical Trials

Randomized On-X Anticoagulation Trial Start of enrollment: 2006 Jun 06
Active, not recruiting
Not Applicable
A Clinical Trial to Evaluate the HeartWare™ Ventricular Assist System (ENDURANCE SUPPLEMENTAL TRIAL) Start of enrollment: 2013 Oct 01
Completed
Not Applicable
MOMENTUM 3 IDE Clinical Study Protocol Start of enrollment: 2014 Sep 02
Completed
Not Applicable

Publications & Presentations

PubMed

4 citations
Practical Considerations for and Outcomes of Interfacility ECMO Transfer of Patients With COVID-19 During a Pandemic: Mayo Clinic Experience.
Ayan Sen, Stephanie Blakeman, Patrick A. DeValeria, Dominique Peworski, Louis A. Lanza, Francis X. Downey, Cory M. Alwardt, Jeffrey G. Dobberpuhl, Matthew DeMarco, Han...> ;Mayo Clinic Proceedings. Innovations, Quality & Outcomes. 2021 Mar 3
14 citations
Impact of statins on cellular respiration and de-differentiation of myofibroblasts in human failing hearts.
Larisa Emelyanova, Amar Sra, Eric G. Schmuck, Amish N. Raval, Francis X Downey, Arshad Jahangir, Farhan Rizvi, Gracious R Ross> ;ESC Heart Failure. 2019 Sep 14
4 citations
Deletion of transcription factor AP-2α gene attenuates fibroblast differentiation into myofibroblast.
Gracious R Ross, Stacie Edwards, Catherine Warner, Peter Homar, Francis X Downey, Larisa Emelyanova, Farhan Rizvi, Arshad Jahangir> ;Journal of Cellular and Molecular Medicine. 2019 Sep 1
92 citations
Comprehensive Analysis of Stroke in the Long-Term Cohort of the MOMENTUM 3 Study.
Paolo C. Colombo, Mandeep R. Mehra, Daniel J. Goldstein, Jerry D. Estep, Christopher T. Salerno, Ulrich P. Jorde, Jennifer A Cowger, Joseph C. Cleveland, Nir Uriel, Ga...> ;Circulation. 2019 Jan 8
9 citations
Xenoreactive antibodies and latent fibrin formation in VAD and cardiac transplant recipients can confound the detection and measurement of anti-AT1R antibodies.
Martin K. Oaks, Karen M Michel, Francis X Downey, Vinay Thohan> ;American Journal of Transplantation. 2018 Nov 1
41 citations
Enhanced store-operated Ca2+ influx and ORAI1 expression in ventricular fibroblasts from human failing heart.
Gracious R Ross, Tanvir Bajwa, Stacie Edwards, Larisa Emelyanova, Farhan Rizvi, Ekhson Holmuhamedov, Paul H Werner, Francis X Downey, A. Jamil Tajik, Arshad Jahangir> ;Biology Open. 2017 Mar 15
5 citations
Role of Echocardiography in the Evaluation of Left Ventricular Assist Devices: the Importance of Emerging Technologies
Luca Longobardo, Christopher Kramer, Scipione Carerj, Concetta Zito, Renuka Jain, Valentin Suma, Vinay Thohan, Nasir Z Sulemanjee, Francis X Downey, Bijoy K. Khandheria> ;Current Cardiology Reports. 2016 May 23
13 citations
Many de novo donor-specific antibodies recognize β2 -microglobulin-free, but not intact HLA heterodimers.
Karen M Michel, R Santella, Jeffery Steers, Ajay Sahajpal, Francis X Downey, Vinay Thohan, Martin K. Oaks> ;HLA. 2016 Apr 6
17 citations
Pharmacological strategies for prevention of postoperative atrial fibrillation.
Mohit K. Turagam, Francis X Downey, David C. Kress, Jasbir Sra, A. Jamil Tajik, Arshad Jahangir> ;Expert Review of Clinical Pharmacology. 2015 Feb 19
21 citations
Practical value of identifying antibodies to cryptic HLA epitopes in cardiac transplantation
Martin K. Oaks, Karen M Michel, Nasir Z Sulemanjee, Vinay Thohan, Francis X Downey> ;The Journal of Heart and Lung Transplantation. 2014 Jul 1
20 citations
Cardiac sarcoid: a chameleon masquerading as hypertrophic cardiomyopathy and dilated cardiomyopathy in the same patient.
Anushree Agarwal, Nasir Z. Sulemanjee, Omar Cheema, Francis X. Downey, A. Jamil Tajik> ;Echocardiography. 2014 May 1
1 citations
Orthotopic Heart Transplantation in a Patient With Corrected L-transposition of Great Arteries and Dextrocardia
Alfred J. Tector, Michael Savitt, C. Jennifer Dankle, Francis X Downey, Jonathan Levin, Rory Nelson, Anjan Gupta, Jonathan Kay> ;The Journal of Heart and Lung Transplantation. 2008 Dec 1
39 citations
Positive heparin-platelet factor 4 antibody complex and cardiac surgical outcomes.
David C. Kress, Solomon Aronson, Monica L. McDonald, Mohammad I. Malik, Ajit B. Divgi, Alfred J. Tector, Francis X Downey, Alfred J. Anderson, Mia Stone, Cassandra Clancy> ;The Annals of Thoracic Surgery. 2007 May 1
19 citations
Comparison of Novacor and HeartMate vented electric left ventricular assist devices in a single institution.
Anantharam V. Kalya, Alfred J. Tector, John Crouch, Francis X Downey, Monica L. McDonald, Alfred J. Anderson, Carla J. Bartoszewski, Jeffery D. Hosenpud> ;The Journal of Heart and Lung Transplantation. 2004 Feb 1
19 citations
A review of leukofiltration in cardiac surgery: the time course of reperfusion injury may facilitate study design of anti-inflammatory effects.
Girolamo A. Ortolano, Gabriel S. Aldea, Kevin J. Lilly, Joseph D Alkon, Frederick Madera, Tarek Murad, Charles P Altenbern, Charles S Tritt, Anthony Capetandes, Nicola...> ;Perfusion. 2002 Mar 1
54 citations
Purely internal thoracic artery grafts: outcomes.
Alfred J. Tector, Monica L. McDonald, David C. Kress, Francis X Downey, Terence M. Schmahl> ;The Annals of Thoracic Surgery. 2001 Aug 1
7 citations
Transition from cardiopulmonary bypass to the HeartMate left ventricular assist device
Alfred J. Tector, David C. Kress, Francis X Downey, Terence M. Schmahl, Kurt A. Dasse, Victor L. Poirier> ;The Annals of Thoracic Surgery. 1998 Mar 1
5 citations
Acute pulmonary hypertension complicating the arterial switch procedure.
Jenny E. Freeman, Serafin Y. DeLeon, Ronald H. Miles, Francis X. Downey, Joanne Hofstra, Jose A. Quinones, Elizabeth A. Fisher, Roque Pifarré> ;Pediatric Cardiology. 1995 Nov 1
3 citations
Reoperation in patients with closed SVG and patent LITA—LAD graft: T-graft approach
Alfred J. Tector, David C. Kress, Susan M. Amundsen, Francis X Downey, Terence M. Schmahl> ;The Annals of Thoracic Surgery. 1995 Jun 1
Disruption of sutured pulmonary valve in Fontan operation.
Francis X. Downey, Serafin Y. DeLeon, David O. Monson, Norbert E. Baumgartner, Robert C. Lichtenberg, Sullivan H, Roque Pifarre> ;The Annals of Thoracic Surgery. 1994 Nov 1
12 citations
Transsternal repair of coarctation and associated cardiac defects.
Serafin Y. DeLeon, Francis X. Downey, Norbert Baumgartner, E. Phillip Ow, Jose A. Quincnes, Ludgerio Torres, Michel N. Ilbawi, Roque Pifarré> ;The Annals of Thoracic Surgery. 1994 Jul 1
5 citations
Obligatory Glenn shunt in fenestrated Fontan.
Serafin Y. DeLeon, Jenny E. Freeman, E. Phillip Ow, Jose A. Quinones, Timothy J. Bell, Elizabeth A. Fisher, Francis X. Downey, Henry J. Sullivan, Roque Pifarré> ;The Annals of Thoracic Surgery. 1993 Sep 1
Complete revascularization with internal thoracic artery grafts.
Tector, A. J., Kress, D. C., Downey, F. X., Schmahl, T. M.> ;Semin Thorac Cardiovasc Surg. 1996 Jan
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