Francisco Soto, MD, Pulmonology, Knoxville, TN, University of Tennessee Medical Center


Pulmonology Knoxville, TN

Critical Care Medicine, Interventional Pulmonology, Pleural Disease, Pulmonary Vascular Medicine

Associate Professor of Medicine / Pulmonary Hypertension Specialist / Advanced Diagnostic and Therapeutic Bronchoscopy / University of Tennessee Medical Center / Knoxville, TN

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  • Dr. Francisco Soto is an Associate Professor of Medicine at University of Tennessee (UT), Knoxville, TN. He is a respected clinician and researcher with 20 years of experience in the management of pulmonary hypertension (PH) and the evaluation of pulmonary manifestations of left heart disease.

    He is a past chair of the pulmonary vascular disease (PVD) network of the American College of Chest Physicians (ACCP) and he is a current steering committee member of the PVD network. He has also served on the editorial board of the journal Advances in Pulmonary Hypertension, the official journal of the Pulmonary Hypertension Association (PHA).

    Areas of pulmonary hypertension-related expertise include the use of prostacyclin infusions (subcutaneous and intravenous), the assessment of connective tissue disease-associated pulmonary hypertension (such as scleroderma) and the evaluation of pulmonary hypertension due to left heart disease and structural heart disease.
    Related areas of excellence include the use and interpretation of cardiothoracic ultrasonography and the evaluation of cardiopulmonary hemodynamics. He personally performs the right heart catheterizations in the cardiac cath lab as part of the comprehensive assessment of patients with known or suspected pulmonary hypertension.

    He has an additional interest and expertise in advanced diagnostic and therapeutic bronchoscopy, including evaluation of lung nodules and lung cancer using endobronchial ultrasound (EBUS), radial EBUS and electromagnetic navigational bronchoscopy (ENB); and management of severe emphysema/COPD symptoms through bronchoscopic placement of endobronchial valves (Zephyr® and Spiration®) for endoscopic lung volume reduction therapy.

    He has been selected by his peers to the Best Doctors in America® list from 2007-2020.

Education & Training

  • Medical College of WisconsinMS, Masters of Science in Epidemiology and Clinical Research, 2002 - 2004
  • Baylor College of Medicine
    Baylor College of MedicineFellowship, Pulmonary Disease and Critical Care Medicine, 1999 - 2002
  • John H. Stroger Hospital of Cook County
    John H. Stroger Hospital of Cook CountyChief Residency, Internal Medicine, 1998 - 1999
  • University of Illinois College of Medicine at Chicago
    University of Illinois College of Medicine at ChicagoResidency, Internal Medicine, 1995 - 1998
  • Universidad del Valle Health Sciences
    Universidad del Valle Health SciencesClass of 1992

Certifications & Licensure

  • KS State Medical License
    KS State Medical License 2017 - 2018
  • TN State Medical License
    TN State Medical License 2017 - 2021
  • MI State Medical License
    MI State Medical License 2017 - 2021
  • WI State Medical License
    WI State Medical License 2002 - 2021
  • IL State Medical License
    IL State Medical License 1995 - 1999
  • American Board of Internal Medicine Critical Care Medicine
  • American Board of Internal Medicine Pulmonary Disease
  • American Board of Internal Medicine Sleep Medicine
  • National Board of EchocardiographyExamination of Special Competence in Critical Care Echocardiography

Awards, Honors, & Recognition

  • Best Doctors in America® 2019-2020 BestDoctors®
  • "London Award" for Dedication to Excellence in Teaching (awarded by the Internal Medicine residents) Graduate School of Medicine, University of Tennessee, Knoxville, TN, 2018
  • CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011-2013

Publications & Presentations



  • 10th International Pulmonary Hypertension Conference and Scientific Sessions 
    Pulmonary Hypertension Association, Orlando, Florida - 6/22/2012

Press Mentions

  • ‘Feeling Good as Hell’: Boston Healthcare Workers Break into Dance to Celebrate Arrival of Pfizer Vaccine | Watch Video
    ‘Feeling Good as Hell’: Boston Healthcare Workers Break into Dance to Celebrate Arrival of Pfizer Vaccine | Watch VideoDecember 19th, 2020

Other Languages

  • Spanish

Hospital Affiliations