FrankAnthonyGrecoMD

Oncology • Nashville, TN

Physician

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Office
250 25th Ave N
Ste 100
Nashville, TN 37203
Phone+1 615-320-5090

Fax+1 615-320-1225
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Education & Training

West Virginia UniversityResidency, Internal Medicine, 1973 - 1974
UCLA David Geffen School of Medicine/UCLA Medical CenterInternship, Internal Medicine, 1972 - 1973
West Virginia University School of MedicineClass of 1972
National Institutes of Health Clinical CenterFellowship, Medical Oncology

Certifications & Licensure

TN State Medical License 1976 - 2025
WV State Medical License 1973 - 1981
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2002-2014
America's Top Doctors for Cancer Castle Connolly, 2005-2013
Nashville Lifestyles Magazine Castle Connolly, 2006
Top MD Consumers Checkbook
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Clinical Trials

Review of Molecular Profiling-Real Time Polymerase Chain Reaction (Rt-Pcr) in Unknown Primary Cancer Start of enrollment: 2009 May 01
Completed

Publications & Presentations

PubMed

3 citations
International consensus on the initial diagnostic workup of cancer of unknown primary.
Iris van der Strate, Fatemeh Kazemzadeh, Iris D Nagtegaal, Debbie Robbrecht, Agnes van de Wouw, Catarina S Padilla, Saskia Duijts, Manel Esteller, F Anthony Greco, Nic...> ;Critical Reviews in Oncology/hematology. 2023 Jan 1
14 citations
Systematic review of the CUP trials characteristics and perspectives for next-generation studies.
Elie Rassy, Roy Chebel, Stergios Boussios, Julie Smith-Gagen, F Anthony Greco, Nicholas Pavlidis, Labaki, C.> ;Cancer Treatment Reviews. 2022 Jun 1
The need for validation of MI GPSai in patients with CUP: Comment on: "Machine learning analysis using 77,044 genomic and transcriptomic profiles to accurately predict...
F. Anthony Greco> ;Translational Oncology. 2021 Aug 1
22 citations
Development and Validation of a Novel Nomogram for Individualized Prediction of Survival in Cancer of Unknown Primary
Kanwal Pratap Singh Raghav, Hyunsoo Hwang, Alexandre A. Jácome, Eric Bhang, Anneleis Willett, Ryan W. Huey, N. Dhillon, Jignesh Modha, Brandon G. Smaglo, Aurelio Matam...> ;Clinical Cancer Research. 2021 Apr 15
25 citations
The role of site-specific therapy for cancers of unknown of primary: A meta-analysis.
Elie El Rassy, Ziad Bakouny, Toni K. Choueiri, Eliezer M. Van Allen, Karim Fizazi, F. Anthony Greco, Nicholas Pavlidis> ;European Journal of Cancer. 2020 Jan 30
16 citations
Renal Cell Carcinoma Presenting as Carcinoma of Unknown Primary Site: Recognition of a Treatable Patient Subset.
F. Anthony Greco, John D. Hainsworth> ;Clinical Genitourinary Cancer. 2018 Aug 1
11 citations
Erlotinib plus either pazopanib or placebo in patients with previously treated advanced non–small cell lung cancer: A randomized, placebo-controlled phase 2 trial with...
David R. Spigel, Howard A. Burris, F. Anthony Greco, Kent C. Shih, Victor G. Gian, Andrew Lipman, Davey B. Daniel, David M. Waterhouse, L Finney, John V. Heymach, John...> ;Cancer. 2018 Jun 1
24 citations
Cancer of Unknown Primary Site: New Treatment Paradigms in the Era of Precision Medicine.
John D. Hainsworth, F. Anthony Greco> ;American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting. 2018 May 23
8 citations
Phase II trial of preoperative pemetrexed plus carboplatin in patients with stage IB-III nonsquamous non-small cell lung cancer (NSCLC).
John D. Hainsworth, David M. Waterhouse, Kent C. Shih, Ralph V. Boccia, Victor M. Priego, Michael McCleod, Fred J. Kudrik, Reed Brian Mitchell, Howard A. Burris, F. An...> ;Lung Cancer. 2018 Apr 1
3 citations
Amrubicin and carboplatin with pegfilgrastim in patients with extensive stage small cell lung cancer: A phase II trial of the Sarah Cannon Oncology Research Consortium.
David R. Spigel, John D. Hainsworth, Dianna Shipley, Tarek Mekhail, John D. Zubkus, David M. Waterhouse, Davey B. Daniel, Howard A. Burris, F. Anthony Greco> ;Lung Cancer. 2018 Mar 1
10 citations
Randomized phase 2 trial of pemetrexed, pemetrexed/bevacizumab, and pemetrexed/carboplatin/bevacizumab in patients with stage IIIB/IV non–small cell lung cancer and an...
David R. Spigel, John D. Hainsworth, Mathew John Joseph, Dianna Shipley, M. Kelly Hagan, Dana S. Thompson, Howard A. Burris, F. Anthony Greco> ;Cancer. 2018 May 1
9 citations
Sorafenib and continued erlotinib or sorafenib alone in patients with advanced non-small cell lung cancer progressing on erlotinib: A randomized phase II study of the ...
David R. Spigel, Mark S. Rubin, Victor G. Gian, Dianna Shipley, Howard A. Burris, Rebecca A. Kosloff, Kent C. Shih, Raven Quinn, F. Anthony Greco, John D. Hainsworth> ;Lung Cancer. 2017 Nov 1
5 citations
First-Line Carboplatin, Pemetrexed, and Panitumumab in Patients with Advanced Non-Squamous KRAS Wild Type (WT) Non-Small-Cell Lung Cancer (NSCLC)
David R. Spigel, Tarek Mekhail, David M. Waterhouse, Terence J. Hadley, Charles D. Webb, Howard A. Burris, John D. Hainsworth, F. Anthony Greco> ;Cancer Investigation. 2017 Aug 1
17 citations
A phase I dose escalation study of NK012, an SN-38 incorporating macromolecular polymeric micelle.
Howard A. Burris, Jeffrey R. Infante, F. Anthony Greco, Dana S. Thompson, John H. Barton, Johanna C. Bendell, Yoshihiro Nambu, Noriko Watanabe, Suzanne F. Jones> ;Cancer Chemotherapy and Pharmacology. 2016 Apr 9
2 citations
Lung Adenocarcinoma with Anaplastic Lymphoma Kinase (ALK) Rearrangement Presenting as Carcinoma of Unknown Primary Site: Recognition and Treatment Implications.
John D Hainsworth, F Anthony Greco> ;Drugs - Real World Outcomes. 2016 Mar 1
10 citations
A phase II trial of erlotinib and bevacizumab for patients with metastatic melanoma
Tejaswi V. Mudigonda, Kenneth Wyman, David R. Spigel, Kimberly B. Dahlman, F. Anthony Greco, Igor Puzanov, Mark C. Kelley, John D. Hainsworth, Jeffrey A. Sosman, Dougl...> ;Pigment Cell & Melanoma Research. 2016 Jan 1
25 citations
Poorly Differentiated Neoplasms of Unknown Primary Site: Diagnostic Usefulness of a Molecular Cancer Classifier Assay
F. Anthony Greco, Wayne J. Lennington, David R. Spigel, John D. Hainsworth> ;Molecular Diagnosis & Therapy. 2015 Mar 11
70 citations
A phase 1 study of the sachet formulation of the oral dual PI3K/mTOR inhibitor BEZ235 given twice daily (BID) in patients with advanced solid tumors
Johanna C. Bendell, Carla Kurkjian, Jeffrey R. Infante, Todd M. Bauer, Howard A. Burris, F. Anthony Greco, Kent C. Shih, D. S. Thompson, Cassie M. Lane, L Finney, Suza...> ;Investigational New Drugs. 2015 Feb 25
29 citations
Paclitaxel/carboplatin with or without belinostat as empiric first-line treatment for patients with carcinoma of unknown primary site: A randomized, phase 2 trial.
John D. Hainsworth, Gedske Daugaard, Thierry Lesimple, Gerdt Hübner, F. Anthony Greco, Michael J. Stahl, Christian Meyer Zum Büschenfelde, Djelila Allouache, Nicolas P...> ;Cancer. 2015 May 15
16 citations
Rituximab with or without bevacizumab for the treatment of patients with relapsed follicular lymphoma.
John D. Hainsworth, F. Anthony Greco, Eric Raefsky, Dana S. Thompson, Scott D. Lunin, James A. Reeves, Lynn White, Raven Quinn, Laura M. DeBusk, Ian W. Flinn> ;Clinical Lymphoma, Myeloma & Leukemia. 2014 Aug 1
49 citations
Gene expression profiling in patients with carcinoma of unknown primary site: from translational research to standard of care
John D. Hainsworth, F. Anthony Greco> ;Virchows Archiv. 2014 Feb 1
11 citations
Cancer of unknown primary site: still an entity, a biological mystery and a metastatic model
F. Anthony Greco> ;Nature Reviews. Cancer. 2014 Jan 1
32 citations
Molecular diagnosis of the tissue of origin in cancer of unknown primary site: useful in patient management.
F. Anthony Greco> ;Current Treatment Options in Oncology. 2013 Aug 29
5 citations
The impact of molecular testing on treatment of cancer of unknown primary origin.
F. Anthony Greco> ;Oncology. 2013 Aug 1
Reply to M.-E. Percival et al and L.B. Saltz.
John D. Hainsworth, David R. Spigel, Mark S. Rubin, Ralph V. Boccia, F. Anthony Greco> ;Journal of Clinical Oncology. 2013 Jul 1
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Professional Memberships

American Society of Clinical Oncology - ASCO
Member

Hospital Affiliations

Ascension Saint ThomasNashville, Tennessee
TriStar Centennial Medical CenterNashville, Tennessee