FrankJJaconoMD

Pulmonology • Cleveland, OH

Critical Care Medicine, Pleural Disease

Associate Professor, Medicine, Case Western Reserve University School of Medicine

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Office
UH Cleveland Medical Center
11100 Euclid Ave Department of Medicine-Pulmonary/Critical Care
Cleveland, OH 44106
Phone+1 216-844-3201

Fax+1 216-844-2187
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Education & Training

Case Western Reserve University/University Hospitals Cleveland Medical CenterFellowship, Pulmonary Disease and Critical Care Medicine, 2001 - 2004
Case Western Reserve University/University Hospitals Cleveland Medical CenterResidency, Internal Medicine, 1998 - 2001
Washington University in St. Louis School of MedicineClass of 1998

Certifications & Licensure

OH State Medical License 2004 - 2024
American Board of Internal Medicine Critical Care Medicine
American Board of Internal Medicine Pulmonary Disease

Publications & Presentations

PubMed

Peritoneal sepsis caused by Escherichia coli triggers brainstem inflammation and alters the function of sympatho-respiratory control circuits.
Kola, G., Clifford, C., Campanaro, C., Dhingra, R., Dutschmann, M., Dick, T., Jacono, F.> ;Journal of Neuroinflammation. 2024 Feb 8
Keeping Cardiac Arrest Documentation Alive in the Electronic Medical Record.
Pallavi Sharma, Gavriella Pora, Paarth Sharma, Frank J Jacono, Maroun Matta, Simran Singh, Matthew J Stull> ;ATS Scholar. 2023 Dec 1
1 citations
Dynamics of ventilatory pattern variability and Cardioventilatory Coupling during systemic inflammation in rats.
Cara K Campanaro, David E Nethery, Fei Guo, Farhad Kaffashi, Kenneth A Loparo, Frank J Jacono, Thomas E Dick, Yee-Hsee Hsieh> ;Frontiers in Network Physiology. 2023 Jan 1
1 citations
Cannabinoid Receptor mRNA Expression in Central and Peripheral Tissues in a Rodent Model of Peritonitis.
Kofi-Kermit A Horton, Cara K Campanaro, Caitlyn Clifford, David E Nethery, Kingman P Strohl, Frank J Jacono, Thomas E Dick> ;Cannabis and Cannabinoid Research. 2023 Jun 1
3 citations
Do Interviews Really Matter in Generating Programs and Applicants' Rank Lists for the Match?
Christopher Di Felice, Pallavi Sharma, David A Folt, Rodney J Folz, Frank Jacono, Shine Raju, Mohammad A Shatat, Joanne McKell, Anna May, Maroun Matta> ;Southern Medical Journal. 2022 Apr 1
7 citations
Inhibiting Mycobacterium abscessus Cell Wall Synthesis: Using a Novel Diazabicyclooctane β-Lactamase Inhibitor To Augment β-Lactam Action.
Khalid M Dousa, Sebastian G Kurz, Magdalena A Taracila, Christopher R Bethel, William Schinabeck, Barry N Kreiswirth, Sheldon T Brown, W Henry Boom, Richard S Hotchkis...> ;Mbio. 2022 Feb 22
3 citations
Combined Radiomic and Visual Assessment for Improved Detection of Lung Adenocarcinoma Invasiveness on Computed Tomography Scans: A Multi-Institutional Study.
Pranjal Vaidya, Kaustav Bera, Philip A Linden, Amit Gupta, Prabhakar Shantha Rajiah, David R Jones, Matthew Bott, Harvey Pass, Robert Gilkeson, Frank Jacono, Kevin Li-...> ;Frontiers in Oncology. 2022 Jan 1
20 citations
Safety and efficacy of multipotent adult progenitor cells in acute respiratory distress syndrome (MUST-ARDS): a multicentre, randomised, double-blind, placebo-controll...
Geoff Bellingan, F Jacono, J Bannard-Smith, David Brealey, Nuala J. Meyer, David R Thickett, Duncan Young, Andrew Bentley, B J McVerry, Richard G. Wunderink, K C Doers...> ;Intensive Care Medicine. 2021 Nov 23
4 citations
A Novel Nodule Edge Sharpness Radiomic Biomarker Improves Performance of Lung-RADS for Distinguishing Adenocarcinomas from Granulomas on Non-Contrast CT Scans.
Mehdi Alilou, Prateek Prasanna, Kaustav Bera, Amit Gupta, Prabhakar Rajiah, Michael Yang, Frank J. Jacono, Vamsidhar Velcheti, Robert C. Gilkeson, Philip A. Linden, An...> ;Cancers. 2021 Jun 3
4 citations
Acute Responses to Oxygen Delivery via High Flow Nasal Cannula in Patients with Severe Chronic Obstructive Pulmonary Disease—HFNC and Severe COPD
Amy Attaway, Jihane Faress, Frank J. Jacono, Srinivasan Dasarathy> ;Journal of Clinical Medicine. 2021 Apr 21
16 citations
Distinguishing granulomas from adenocarcinomas by integrating stable and discriminating radiomic features on non-contrast computed tomography scans.
Mohammadhadi Khorrami, Kaustav Bera, Rajat Thawani, Prabhakar Rajiah, Amit Gupta, Pingfu Fu, Philip A. Linden, Nathan A. Pennell, Frank J. Jacono, Robert C. Gilkeson, ...> ;European Journal of Cancer. 2021 Mar 17
5 citations
Assessment and Management of Delirium in Critically Ill Veterans.
Denise Kresevic, Donna M. Miller, Carole W Fuseck, Mia Wade, Laura Whitney, Mary Conley, Joanne Rimac, Frank J. Jacono, Heather L O'Leary-Wilson, Christopher J. Burant> ;Critical Care Nurse. 2020 Aug 1
16 citations
Brainstem inflammation modulates the ventilatory pattern and its variability after acute lung injury in rodents.
Yee-Hsee Hsieh, David Litvin, Abigail Rose Zaylor, David Nethery, Thomas E. Dick, Frank J. Jacono> ;The Journal of Physiology. 2020 Jul 1
14 citations
INSMA: An integrated system for multimodal data acquisition and analysis in the intensive care unit.
Yingcheng Sun, Fei Guo, Farhad Kaffashi, Frank J. Jacono, Michael DeGeorgia, Kenneth A. Loparo> ;Journal of Biomedical Informatics. 2020 Jun 1
12 citations
Peripheral-to-central immune communication at the area postrema glial-barrier following bleomycin-induced sterile lung injury in adult rats.
David Litvin, Scott J. Denstaedt, Lauren F. Borkowski, Nicole L. Nichols, Thomas E. Dick, Corey Smith, Frank J. Jacono> ;Brain, Behavior, and Immunity. 2020 Feb 22
9 citations
Acute lung injury in neonatal rats causes postsynaptic depression in nucleus tractus solitarii second-order neurons
Paulina M. Getsy, Catherine A. Mayer, Peter M. MacFarlane, Frank J. Jacono, Christopher G. Wilson> ;Respiratory Physiology & Neurobiology. 2019 Nov 1
Author Correction: Quantitative vessel tortuosity: A potential CT imaging biomarker for distinguishing lung granulomas from adenocarcinomas
Mehdi Alilou, Mahdi Orooji, Niha Beig, Prateek Prasanna, Prabhakar Rajiah, Christopher Donatelli, Vamsidhar Velcheti, Sagar Rakshit, Michael Yang, Frank J. Jacono, Rob...> ;Scientific Reports. 2019 Oct 29
12 citations
Mortality in Adults with Cystic Fibrosis Requiring Mechanical Ventilation. Cross-Sectional Analysis of Nationwide Events.
Matthew Siuba, Amy Attaway, Joe Zein, Xiaofeng Wang, Xiaozhen Han, Steven Strausbaugh, Frank J. Jacono, Elliot C. Dasenbrook> ;Annals of the American Thoracic Society. 2019 Aug 1
9 citations
Ventilatory pattern variability as a biometric for severity of acute lung injury in rats.
Benjamin P. Young, Kenneth A. Loparo, Thomas E. Dick, Frank J. Jacono> ;Respiratory Physiology & Neurobiology. 2019 Jul 1
188 citations
Perinodular and Intranodular Radiomic Features on Lung CT Images Distinguish Adenocarcinomas from Granulomas
Niha Beig, Mohammadhadi Khorrami, Mehdi Alilou, Prateek Prasanna, Nathaniel Braman, Mahdi Orooji, Sagar Rakshit, Kaustav Bera, Prabhakar Rajiah, Jennifer Ginsberg, Chr...> ;Radiology. 2019 Mar 1
11 citations
AGTR2 absence or antagonism prevents cystic fibrosis pulmonary manifestations.
Rebecca J. Darrah, Frank J. Jacono, Neha Joshi, Anna L. Mitchell, Abdus Sattar, Cara Campanaro, Paul Litman, Jennifer Frey, David E. Nethery, Eric Barbato, Craig A. Ho...> ;Journal of Cystic Fibrosis. 2019 Jan 1
17 citations
Quantitative vessel tortuosity: A potential CT imaging biomarker for distinguishing lung granulomas from adenocarcinomas
Mehdi Alilou, Mahdi Orooji, Niha Beig, Prateek Prasanna, Prabhakar Rajiah, Christopher Donatelli, Vamsidhar Velcheti, Sagar Rakshit, Michael Yang, Frank J. Jacono, Rob...> ;Scientific Reports. 2018 Oct 16
14 citations
Mid-cervical spinal cord contusion causes robust deficits in respiratory parameters and pattern variability.
Philippa M. Warren, Cara Campanaro, Frank J. Jacono, Warren J. Alilain> ;Experimental Neurology. 2018 Aug 1
Periodicity: A characteristic of heart rate variability modified by the type of mechanical ventilation after acute lung injury
Anurak Thungtong, Matthew F. Knoch, Frank J. Jacono, Thomas E. Dick, Kenneth A. Loparo> ;Frontiers in Physiology. 2018 Jun 19
12 citations
Lung-injury depresses glutamatergic synaptic transmission in the nucleus tractus solitarii via discrete age-dependent mechanisms in neonatal rats.
David Litvin, Thomas E. Dick, Corey Smith, Frank J. Jacono> ;Brain, Behavior, and Immunity. 2018 May 1
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Press Mentions

Athersys Announces Commencement of Patient Enrollment in the MACOVIA Study, a Pivotal Phase 2/3 Trial Evaluating MultiStem® Cell Therapy for COVID-19 Induced ARDSMay 5th, 2020
UH Cleveland Medical Center Will Be the First Clinical Site for a New Athersys Inc. TrialMay 1st, 2020
Athersys and University Hospitals Cleveland Medical Center Announce Activation of the First Clinical Site for the MACOVIA Study, a Pivotal Phase 2/3 Study Evaluating MultiStem® Cell Therapy for COVID-19 Induced ARDSMay 1st, 2020
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