FrankCSciurbaMD

Pulmonology • Pittsburgh, PA

Asthma & COPD, Critical Care Medicine, Interventional Pulmonology, Pulmonary Rehabilitation

Tenured Professor, Medicine, University of Pittsburgh School of Medicine

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Office
3471 5th Ave
Suite 1211
Pittsburgh, PA 15213
Phone+1 412-648-6494
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Summary

Dr. Frank Sciurba is a pulmonologist in Pittsburgh, PA and is affiliated with UPMC Presbyterian. He received his medical degree from University of Chicago Pritzker School of Medicine and has been in practice 35 years. He specializes in Personalized approaches to COPD and Emphysema, and pulmonary rehabilitation and is experienced in pulmonary function testing, cardiopulmonary exercise testing, device and biologic intervention in copd, and clinical trials and translational research in copd.

Education & Training

UPMC Medical EducationFellowship, Pulmonary Disease and Critical Care Medicine, 1986 - 1988
UPMC Medical EducationResidency, Internal Medicine, 1982 - 1984
University of Chicago Division of the Biological Sciences The Pritzker School of MedicineClass of 1982

Certifications & Licensure

PA State Medical License 1984 - 2024
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Pulmonary Disease

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011

Clinical Trials

Endobronchial Valve for Emphysema Palliation Trial (VENT) Start of enrollment: 2004 Jan 01
Completed
Phase 3
Emphysema Research Registry and Biosample Repository Start of enrollment: 2000 Aug 01
Recruiting
Benefits of Lightweight Ambulatory Oxygen Systems for Individuals With Chronic Obstructive Pulmonary Disease Start of enrollment: 2005 Mar 01
Terminated
Not Applicable
Macrolide Azithromycin to Prevent Rapid Worsening of Symptoms Associated With Chronic Obstructive Pulmonary Disease Start of enrollment: 2006 Mar 01
Completed
Not Applicable
Long-term Oxygen Treatment Trial Start of enrollment: 2009 Jan 01
Completed
Phase 3
Simvastatin Therapy for Moderate and Severe COPD Start of enrollment: 2010 Mar 01
Terminated
Phase 3
Lung Volume Reduction Coil Treatment in Patients With Emphysema (RENEW) Study Start of enrollment: 2012 Oct 01
Terminated
Not Applicable
The Use of High Frequency Oscillations With NIV in Hypercapnic COPD Participants Start of enrollment: 2015 Nov 13
Terminated
Not Applicable
Evaluation of the Safety and Efficacy of TLD in Patients With COPD Start of enrollment: 2019 May 23
Active, not recruiting
Not Applicable
Study of Humidified Air to Improve Mucociliary Clearance (MCC) in COPD Start of enrollment: 2019 Jul 15
Completed
Not Applicable
An Observational Study of Beta-Blocker Use in Patients With COPD and Acute MI Start of enrollment: 2020 Jun 28
Completed
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Publications & Presentations

PubMed

Subphenotypes of self-reported symptoms and outcomes in long COVID: a prospective cohort study with latent class analysis.
Georgios D Kitsios, Shawna Blacka, Jana J Jacobs, Taaha Mirza, Asma Naqvi, Heather Gentry, Cathy Murray, Xiaohong Wang, Konstantin Golubykh, Hafiz Qurashi, Akash Dodia...> ;BMJ Open. 2024 Mar 14
STAR Has Better Discrimination for Mortality than ERS/ATS COPD Severity Classification.
Nakhmani, A., Strand, M., Silverman, E., Wilson, C., Bodduluri, S., Bhatt, S., Fortis, S., Sciurba, F.> ;American Journal of Respiratory and Critical Care Medicine. 2024 Feb 2
Cell-free DNA levels associate with COPD exacerbations and mortality.
Ware, S., Giordano, L., Redding, K., Rumsey, W., Bates, S., Zhang, Y., Nouraie, S., Kaufman, B., Kliment, C., Sciurba, F.> ;Respiratory Research. 2024 Jan 18
Long-Term Effects of COVID-19 on the Cardiopulmonary System in Adults and Children: Current Status and Questions to be Resolved by the National Institutes of Health Re...
Altman, N. J., Franz Rischard, Natasha Altman, Jacqueline Szmuszkovicz, Frank Sciurba, Erika Berman-Rosenzweig, Simon Lee, Sankaran Krishnan, Ngan Truong, John Wood, A...> ;Chest. 2024 Apr 1
Utility of rehabilitation prior to bronchoscopic lung volume reduction:analysis of the VENT trial.
Judith Maria Brock, Konstantina Kontogianni, Frank C Sciurba, Gerard J Criner, Felix Herth> ;ERJ Open Research. 2024 Jan 1
Bronchial rheoplasty for chronic bronchitis: 2-year results from a US feasibility study with RheOx.
Sciurba, F., Dransfield, M., Kim, V., Marchetti, N., Comellas, A., Hogarth, D., Majid, A.> ;BMJ Open Respiratory Research. 2023 Dec 26
Validation of Constant Work Rate Cycling Endurance Time for Use in Chronic Obstructive Pulmonary Disease Clinical Trials.
Richard Casaburi, Debora Merrill, Nancy Kline Leidy, Nicholas Locantore, Thomas Dolmage, Judith Garcia-Aymerich, Roger Goldstein, Gale Harding, François Maltais, Denis...> ;Annals of the American Thoracic Society. 2023 Dec 18
1 citations
Reply to Neder, to Ogata, and to Graham.
Surya P Bhatt, Arie Nakhmani, Spyridon Fortis, Matthew J Strand, Edwin K Silverman, Frank C Sciurba, Sandeep Bodduluri> ;American Journal of Respiratory and Critical Care Medicine. 2024 Feb 1
Reply to Gan, to Calzetta, and to Poor.
Antonio Anzueto, Igor Z Barjaktarevic, Thomas M Siler, Tara Rheault, Thomas Bengtsson, Kathleen Rickard, Frank Sciurba> ;American Journal of Respiratory and Critical Care Medicine. 2024 Jan 15
Returning incidentally discovered Hepatitis C RNA-seq results to COPDGene study participants.
Bhatt, S. P., Edwin K Silverman, Arthur Y Kim, Barry J Make, Elizabeth A Regan, Jarrett D Morrow, Craig P Hersh, James O'Brien, James D Crapo, Nadia N Hansel, Gerard C...> ;NPJ Genomic Medicine. 2023 Oct 31
2 citations
Clonal Somatic Mutations in Chronic Lung Diseases Are Associated with Reduced Lung Function.
Jeong H Yun, M A Wasay Khan, Auyon Ghosh, Brian D Hobbs, Peter J Castaldi, Craig P Hersh, Peter G Miller, Carlyne D Cool, Frank Sciurba, Lucas Barwick, Andrew H Limper...> ;American Journal of Respiratory and Critical Care Medicine. 2023 Dec 1
Lifestyle Intervention and Excess Weight in Chronic Obstructive Pulmonary Disease (COPD): INSIGHT COPD Randomized Clinical Trial.
David H Au, Emily Gleason, Rachel Hunter-Merrill, Anna E Barón, Margaret Collins, Corina Ronneberg, Nan Lv, Peter Rise, Travis Hee Wai, Robert Plumley, Stephen R Wisni...> ;Annals of the American Thoracic Society. 2023 Dec 1
Incident low muscle mass is associated with greater lung disease and lower circulating leptin in a tobacco-exposed longitudinal cohort.
Richard H Zou, S Mehdi Nouraie, Chad Karoleski, Yingze Zhang, Frank C Sciurba, Daniel E Forman, Jessica Bon> ;Respiratory Research. 2023 Sep 22
Integrative genetic and genomic networks identify microRNA associated with COPD and ILD.
Kaminski, N., Pavel, A., Garrison, C., Luo, L., Liu, G., Taub, D., Xiao, J., Juan-Guardela, B., Tedrow, J., Alekseyev, Y., Yang, I., Geraci, M., Sciurba, F., Schwartz,...> ;Scientific Reports. 2023 Aug 11
8 citations
Ensifentrine, a Novel Phosphodiesterase 3 and 4 Inhibitor for the Treatment of Chronic Obstructive Pulmonary Disease: Randomized, Double-Blind, Placebo-controlled, Mul...
Antonio Anzueto, Igor Z Barjaktarevic, Thomas M Siler, Tara Rheault, Thomas Bengtsson, Kathleen Rickard, Frank Sciurba> ;American Journal of Respiratory and Critical Care Medicine. 2023 Aug 15
3 citations
FEV/FVC Severity Stages for Chronic Obstructive Pulmonary Disease.
Surya P Bhatt, Arie Nakhmani, Spyridon Fortis, Matthew J Strand, Edwin K Silverman, Frank C Sciurba, Sandeep Bodduluri> ;American Journal of Respiratory and Critical Care Medicine. 2023 Sep 15
Deep Learning Integration of Chest Computed Tomography Imaging and Gene Expression Identifies Novel Aspects of COPD.
Junxiang Chen, Zhonghui Xu, Li Sun, Ke Yu, Craig P Hersh, Adel Boueiz, John E Hokanson, Frank C Sciurba, Edwin K Silverman, Peter J Castaldi, Kayhan Batmanghelich> ;Chronic Obstructive Pulmonary Diseases. 2023 Oct 26
1 citations
Design of Lung Transplant Go (LTGO): A randomized controlled trial evaluating the efficacy of a telerehabilitation behavioral exercise intervention to improve physical...
Melissa L Vendetti, Seol Ju Esther Moon, Christopher C Imes, Andrea Hergenroeder, Frank Sciurba, Elizabeth Lendermon, Joseph Pilewski, Dianxu Ren, Bambang Parmanto, Ba...> ;Contemporary Clinical Trials Communications. 2023 Jun 1
Clinically stable covid-19 patients presenting to acute unscheduled episodic care venues have increased risk of hospitalization: secondary analysis of a randomized con...
Joseph Bledsoe, Scott C Woller, Maria Brooks, Frank C Sciurba, Jerry A Krishnan, Deborah Martin, Peter Hou, Janet Y Lin, Andrei Kindzelski, Eileen Handberg, Bridget-An...> ;BMC Infectious Diseases. 2023 May 15
2 citations
Researching COVID to enhance recovery (RECOVER) pregnancy study: Rationale, objectives and design.
Torri D Metz, Rebecca G Clifton, Richard Gallagher, Rachel S Gross, Leora I Horwitz, Vanessa L Jacoby, Susanne P Martin-Herz, Myriam Peralta-Carcelen, Harrison T Reede...> ;Medrxiv. 2023 Apr 24
Lung volume reduction in COPD: scope or surgery.
Francesca Polverino, Frank Sciurba> ;The European Respiratory Journal. 2023 Apr 1
2 citations
Distinct COPD subtypes in former smokers revealed by gene network perturbation analysis.
Kristina L Buschur, Craig Riley, Aabida Saferali, Peter Castaldi, Grace Zhang, Francois Aguet, Kristin G Ardlie, Peter Durda, W Craig Johnson, Silva Kasela, Yongmei Li...> ;Respiratory Research. 2023 Jan 25
6 citations
Researching COVID to Enhance Recovery (RECOVER) adult study protocol: Rationale, objectives, and design.
Chu, H. Y., Leora I Horwitz, Tanayott Thaweethai, Shari B Brosnahan, Mine S Cicek, Megan L Fitzgerald, Jason D Goldman, Rachel Hess, S L Hodder, Vanessa L Jacoby, Mich...> ;Plos One. 2023 Jan 1
Researching COVID to enhance recovery (RECOVER) pregnancy study: Rationale, objectives and design.
Metz, T., Clifton, R., Gallagher, R., Gross, R., Horwitz, L., Jacoby, V., Martin-Herz, S., Peralta-Carcelen, M., Reeder, H., Beamon, C., Chan, J., Chang, A., Costantin...> ;Plos One. 2023 Jan 1
1 citations
A Model to Predict Residual Volume from Forced Spirometry Measurements in Chronic Obstructive Pulmonary Disease.
John W Evankovich, S M Nouraie, Frank C Sciurba> ;Chronic Obstructive Pulmonary Diseases. 2023 Jan 25
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Press Mentions

PRE-PROOF Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation PRE-PROOFDecember 22nd, 2022
COPD Community: Where to Find SupportJanuary 28th, 2021
Managing Chronic Lung Diseases During the PandemicApril 29th, 2020
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Grant Support

Peripheral Markers Of Phenotypic Heterogeneity In COPDNational Heart, Lung, And Blood Institute2007–2012
Molecular And Cellular Determinants Of Disease Heterogeneity In COPDNational Heart, Lung, And Blood Institute2007–2012
ClinicalNational Heart, Lung, And Blood Institute2007–2012
AdministrativeNational Heart, Lung, And Blood Institute2007–2012
Lung Genomics Research ConsortiumNational Heart, Lung, And Blood Institute2010
Lung Genomics Research ConsortiumNational Heart, Lung, And Blood Institute2009–2010
UnknownNational Heart, Lung, And Blood Institute2007
COPD Clinical Research NetworkNational Heart, Lung, And Blood Institute2004–2007
Lung Tissue Research Consortium (Ltrc): Clinical CenterNational Center For Research Resources2005
Feasibility Of Retinoid Therapy For Emphysema (FORTE)National Center For Research Resources2004
Feasibility Studies On Retinoid Treatment In EmphysemaDivision Of Lung Diseases1999–2000