FranklinJosephZieveMD

Associate Professor, Internal Medicine, Virginia Commonwealth University, Medical College of Virginia School of Medicine. Preventative Cardiology

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Office
1201 Broad Rock Blvd
Hunter Holmes Mcguire Va Medical Center
Richmond, VA 23249
Phone+1 804-675-5151

Fax+1 804-675-5139
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Education & Training

University of MinnesotaResidency, Internal Medicine, 1974 - 1975
University of MinnesotaInternship, Internal Medicine, 1971 - 1972
University of Minnesota Medical SchoolClass of 1971

Certifications & Licensure

VA State Medical License 1979 - 2024
MN State Medical License 1972 - 1983
American Board of Internal Medicine Internal Medicine

Clinical Trials

VA NEPHRON-D: Diabetes iN Nephropathy Study Start of enrollment: 2008 Jul 01
Terminated
Phase 3
Study to Evaluate the Effects of BMS-813160 on Protein Loss in the Urine of Subjects With Type 2 Diabetes and Diabetic Kidney Disease Start of enrollment: 2013 Mar 18
Terminated
Phase 2

Publications & Presentations

PubMed

10 citations
Efficacy and safety of alirocumab in statin-intolerant patients over 3 years: open-label treatment period of the ODYSSEY ALTERNATIVE trial.
Patrick M. Moriarty, Paul D. Thompson, Christopher P. Cannon, John R. Guyton, Jean Bergeron, Franklin J. Zieve, Eric Bruckert, Terry A. Jacobson, Marie T. Baccara-Dine...> ;Journal of Clinical Lipidology. 2020 Jan 1
3 citations
Inverse relationship between high-density lipoprotein cholesterol raising and high-sensitivity C-reactive protein reduction in older patients treated with lipid-loweri...
W. Virgil Brown, JoAnne M. Foody, Franklin J. Zieve, Joanne E. Tomassini, Arvind Shah, Andrew M. Tershakovec> ;Journal of Clinical Lipidology. 2010 May 1
332 citations
Efficacy and safety of alirocumab vs ezetimibe in statin-intolerant patients, with a statin rechallenge arm: The ODYSSEY ALTERNATIVE randomized trial
Patrick M. Moriarty, Paul D. Thompson, Christopher P. Cannon, John R. Guyton, Jean Bergeron, Franklin J. Zieve, Eric Bruckert, Terry A. Jacobson, Stephen L. Kopecky, M...> ;Journal of Clinical Lipidology. 2015 Nov 1
17 citations
Atorvastatin 10 mg plus ezetimibe versus titration to atorvastatin 40 mg: attainment of European and Canadian guideline lipid targets in high-risk subjects ≥65 years
Christian Constance, Ori Ben-Yehuda, Nanette K. Wenger, Franklin J. Zieve, Jianxin Lin, Mary E. Hanson, Robert S. Lowe, Andrew M. Tershakovec> ;Lipids in Health and Disease. 2014 Jan 13
11 citations
Non-high-density lipoprotein cholesterol reporting and goal attainment in primary care.
Salim S. Virani, Degang Wang, Supicha S. Chitwood, Cassie R. Landrum, Franklin J. Zieve, Christie M. Ballantyne, Laura A. Petersen> ;Journal of Clinical Lipidology. 2012 Nov 1
113 citations
The duration of diabetes affects the response to intensive glucose control in type 2 subjects: the VA Diabetes Trial
William C. Duckworth, Carlos Abraira, Thomas E. Moritz, Stephen N. Davis, Nicholas V. Emanuele, Steven Goldman, Rodney A. Hayward, Grant D. Huang, Jennifer B. Marks, P...> ;Journal of Diabetes and Its Complications. 2011 Nov 1
22 citations
Safety and Efficacy of Ezetimibe/Simvastatin Combination Versus Atorvastatin Alone in Adults ≥65 Years of Age With Hypercholesterolemia and With or at Moderately High/...
JoAnne M. Foody, W. Virgil Brown, Franklin Zieve, Adeniyi J. Adewale, Doreen Flaim, Robert S. Lowe, Charlotte Jones-Burton, Andrew M. Tershakovec> ;The American Journal of Cardiology. 2010 Nov 1
34 citations
Safety and Efficacy of Ezetimibe Added to Atorvastatin Versus Up Titration of Atorvastatin to 40 mg in Patients ≥65 Years of Age (from the ZETia in the ELDerly [ZETELD...
Franklin J. Zieve, Nanette K. Wenger, Ori Ben-Yehuda, Christian Constance, Steven R. Bird, Raymond Lee, Mary E. Hanson, Charlotte Jones-Burton, Andrew M. Tershakovec> ;The American Journal of Cardiology. 2010 Mar 1
3187 citations
Glucose Control and Vascular Complications in Veterans with Type 2 Diabetes
William C. Duckworth, Carlos Abraira, Thomas E. Moritz, Domenic J. Reda, Nicholas V. Emanuele, Peter D. Reaven, Franklin J. Zieve, Jennifer B. Marks, Stephen N. Davis,...> ;The New England Journal of Medicine. 2009 Dec 10
159 citations
Results of the glucose-lowering effect of WelChol study (GLOWS): a randomized, double-blind, placebo-controlled pilot study evaluating the effect of colesevelam hydroc...
Franklin J. Zieve, Marcia F. Kalin, Sherwyn Schwartz, Michael R. Jones, William L. Bailey> ;Clinical Therapeutics. 2007 Jan 1
16 citations
Efficacy and safety of coadministration of ezetimibe and simvastatin in African-American patients with primary hypercholesterolemia.
Roxanne A Rodney, Daniel Sugimoto, Bernard Wagman, Franklin Zieve, Boris Kerzner, John Strony, Bo Yang, Ramachandran Suresh, Enrico P. Veltri> ;Journal of the National Medical Association. 2006 May 1
54 citations
Comparison of efficacy and safety of rosuvastatin versus atorvastatin in African-American patients in a six-week trial.
Keith C. Ferdinand, Luther T. Clark, Karol E. Watson, Ryan C. Neal, Clinton D. Brown, B. Waine Kong, Boisey O. Barnes, William R. Cox, Franklin J. Zieve, Jonathan L. I...> ;The American Journal of Cardiology. 2006 Jan 15
49 citations
Efficacy of extended-release niacin with lovastatin for hypercholesterolemia: assessing all reasonable doses with innovative surface graph analysis.
William Insull, Mark E. McGovern, Helmut G. Schrott, Paul D. Thompson, J. Robin Crouse, Franklin J. Zieve, John Corbelli> ;Archives of Internal Medicine. 2004 May 24
11 citations
The metabolic syndrome: diagnosis and treatment.
Franklin J. Zieve> ;Clinical Cornerstone. 2004 Jan 1
46 citations
Comparison of efficacy and safety of atorvastatin (10 mg) with simvastatin (10 mg) at six weeks
William Insull, Stephanie Kafonek, David Goldner, Franklin J. Zieve> ;The American Journal of Cardiology. 2001 Mar 1
19 citations
The Veterans Affairs Implantable Insulin Pump Study: Effect on cardiovascular risk factors
William C. Duckworth, Christopher D. Saudek, Anita Giobbie-Hurder, William G. Henderson, Robert R. Henry, David E. Kelley, Steven V. Edelman, Franklin Zieve, Robert A....> ;Diabetes Care. 1998 Oct 1
48 citations
Diabetes Prevalence and Hospital and Pharmacy Use in the Veterans Health Administration (1994): Use of an ambulatory care pharmacy-derived database
Leonard M. Pogach, Gerald Hawley, Ruth S. Weinstock, Clark T. Sawin, Harlan Schiebe, Franklin Cutler, Franklin Zieve, Mary Bates, Denis Repke> ;Diabetes Care. 1998 Mar 1
101 citations
Implantable insulin pump vs multiple-dose insulin for non-insulin-dependent diabetes mellitus: a randomized clinical trial. Department of Veterans Affairs Implantable ...
Christopher D. Saudek, William C. Duckworth, Anita Giobbie-Hurder, William G. Henderson, Robert R. Henry, David E. Kelley, Steven V. Edelman, Franklin Zieve, Robert A....> ;JAMA. 1996 Oct 23
2 citations
Presentation of the Julius M. Friedenwald Medal to John T. Farrar, M.D.
Z. Reno Vlahcevic, Alvin M. Zfass, Franklin J. Zieve> ;Gastroenterology. 1995 Dec 1
1 citations
Splenic protein synthesis in magnesium deficiency: mechanism of the inhibition
Kenneth A. Freude, Franklin J. Zieve, Leslie Zieve> ;The Journal of Nutrition. 1978 Oct 1
9 citations
Effects of Magnesium Deficiency on Protein and Nucleic Acid Synthesis in Vivo
Franklin J. Zieve, Kenneth A. Freude, Leslie Zieve> ;The Journal of Nutrition. 1977 Dec 1
11 citations
The hydrolytic and transacylation activity of the phospholipase A1 purified from human post-heparin plasma.
Moseley Waite, Patricia Sisson, Kenneth A. Freude, Franklin J. Zieve> ;Biochemical and Biophysical Research Communications. 1975 Nov 3
59 citations
SYNERGISM BETWEEN AMMONIA AND FATTY ACIDS IN THE PRODUCTION OF COMA: IMPLICATIONS FOR HEPATIC COMA
Franklin J. Zieve, Leslie Zieve, William M. Doizaki, Robert B. Gilsdorf> ;The Journal of Pharmacology and Experimental Therapeutics. 1974 Oct 1
14 citations
Effects of the carcinogen N-acetoxy-2-fluorenylacetamide on the template properties of deoxyribonucleic acid.
Franklin J. Zieve> ;Molecular Pharmacology. 1973 Sep 1
54 citations
Activation of glycogen synthetase and inactivation of phosphorylase kinase by the same phosphoprotein phosphatase
Franklin J. Zieve, Walter H. Glinsmann> ;Biochemical and Biophysical Research Communications. 1973 Feb 5
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Professional Memberships

American Association of Clinical Endocrinologists - AACE
Member

Hospital Affiliations

Hunter Holmes McGuire Veterans Affairs Medical Center-RichmondRichmond, Virginia