FredLevineMDPhD

PubMed

• 10 citations
  Liver fat storage is controlled by HNF4α through induction of lipophagy and is reversed by a potent HNF4α agonist.
  Seung-Hee Lee, Vimal Veeriah, Fred Levine> ;Cell Death & Disease. 2021 Jun 11
• 6 citations
  Insulin acts as a repressive factor to inhibit the ability of PAR2 to induce islet cell transdifferentiation.
  Seung-Hee Lee, Ergeng Hao, David Scharp, Fred Levine> ;Islets. 2018 May 3
• 17 citations
  High-throughput screening and bioinformatic analysis to ascertain compounds that prevent saturated fatty acid-induced β-cell apoptosis.
  Seung-Hee Lee, Daniel Andrade Da Cunha, Carlo Piermarocchi, Giovanni Paternostro, Anthony B. Pinkerton, Laurence Ladrière, Piero Marchetti, Decio L. Eizirik, Miriam Cn...> ;Biochemical Pharmacology. 2017 Aug 15
• 13 citations
  PAR2 regulates regeneration, transdifferentiation, and death.
  Ron Piran, Seung-Hee Lee, Pia Kuss, Ergeng Hao, Robbin Newlin, José Luis Millán, Fred Levine> ;Cell Death & Disease. 2016 Nov 3
• 4 citations
  Maternal embryonic leucine zipper kinase regulates pancreatic ductal, but not β‐cell, regeneration
  Cheng-Ho Chung, Amber Miller, Andreas Panopoulos, Ergeng Hao, Robert L. Margolis, Alexey V. Terskikh, Fred Levine> ;Physiological Reports. 2014 Sep 1
• 47 citations
  Pharmacological induction of pancreatic islet cell transdifferentiation: relevance to type I diabetes
  Ron Piran, Seung-Hee Lee, Li Cr, Charbono A, Bradley Lm, Fred Levine> ;Cell Death & Disease. 2014 Jul 31
• 13 citations
  Efficient β-cell regeneration by a combination of neogenesis and replication following β-cell ablation and reversal of pancreatic duct ligation
  Ergeng Hao, Seung-Hee Lee, Fred Levine> ;Stem Cells. 2013 Nov 1
• 19 citations
  Identification of Alverine and Benfluorex as HNF4α Activators
  Seung-Hee Lee, Sonalee Athavankar, Tom Cohen, Ron Piran, Alice Kiselyuk, Fred Levine> ;ACS Chemical Biology. 2013 Aug 16
• 7 citations
  Induction of β-cell replication by a synthetic HNF4α antagonist.
  Seung-Hee Lee, Ron Piran, Ehud Keinan, Anthony B. Pinkerton, Fred Levine> ;Stem Cells. 2013 Nov 1
• Antipsychotics activate the TGF? pathway effector SMAD3.
  Cohen, T.,Sundaresh, S.,Levine, F.> ;Mol. Psychiatry. 2013 Mar
• 61 citations
  HNF4α Antagonists Discovered by a High-Throughput Screen for Modulators of the Human Insulin Promoter
  Alice Kiselyuk, Seung-Hee Lee, Suzette Farber-Katz, Mingjun Zhang, Sonalee Athavankar, Tom Cohen, Anthony B. Pinkerton, Mao Ye, Paul J. Bushway, Adam D. Richardson, He...> ;Chemistry & Biology. 2012 Jul 27
• 25 citations
  T-cadherin (Cdh13) in association with pancreatic β-cell granules contributes to second phase insulin secretion
  Björn Tyrberg, Philip D.G. Miles, Krist T. Azizian, Martin S. Denzel, Maria L. Nieves, Edward Monosov, Fred Levine, Barbara Ranscht> ;Islets. 2011 Nov 1
• 22 citations
  Id3 upregulates BrdU incorporation associated with a DNA damage response, not replication, in human pancreatic β-cells
  Seung-Hee Lee, Ergeng Hao, Fred Levine, Pamela Itkin-Ansari> ;Islets. 2011 Nov 1
• 16 citations
  β-Cell replication and islet neogenesis following partial pancreatectomy.
  Seung-Hee Lee, Ergeng Hao, Fred Levine> ;Islets. 2011 Jul 1
• 21 citations
  The Id3/E47 axis mediates cell-cycle control in human pancreatic ducts and adenocarcinoma.
  Seung-Hee Lee, Ergeng Hao, Alice Kiselyuk, James Shapiro, David J. Shields, Andrew M. Lowy, Fred Levine, Pamela Itkin-Ansari> ;Molecular Cancer Research. 2011 Jun 1
• 137 citations
  Pancreatic β-cell neogenesis by direct conversion from mature α-cells.
  Cheng-Ho Chung, Ergeng Hao, Ron Piran, Ehud Keinan, Fred Levine> ;Stem Cells. 2010 Sep 1
• 30 citations
  Adult Pancreatic Alpha-Cells: A New Source of Cells for Beta-Cell Regeneration
  Cheng-Ho Chung, Fred Levine> ;The Review of Diabetic Studies. 2010 Aug 10
• 24 citations
  Phenothiazine neuroleptics signal to the human insulin promoter as revealed by a novel high-throughput screen.
  Alice Kiselyuk, Suzette Farber-Katz, Tom Cohen, Seung-Hee Lee, Ifat Geron, Behrad Azimi, Susanne Heynen-Genel, Oded Singer, Jeffrey H. Price, Mark Mercola, Pamela Itki...> ;Journal of Biomolecular Screening. 2010 Jun 14
• 17 citations
  Adult human β‐cell neogenesis?
  Carla Demeterco, Ergeng Hao, Seung-Hee Lee, Pamela Itkin-Ansari, Fred Levine> ;Diabetes, Obesity & Metabolism. 2009 Oct 7
• 9 citations
  Derivation of a Retinoid X Receptor Scaffold from Peroxisome Proliferator-Activated Receptor γ Ligand 1-Di(1H-indol-3-yl)methyl-4-trifluoromethylbenzene
  Marcia I. Dawson, Mao Ye, Xihua Cao, Lulu Farhana, Qiong-Ying Hu, Yong Zhao, Liping Xu, Alice Kiselyuk, Ricardo G. Correa, Li Yang, Tingjun Hou, John C. Reed, Pamela I...> ;Chemmedchem. 2009 Jul 6
• 36 citations
  Coordinated regulation by Shp2 tyrosine phosphatase of signaling events controlling insulin biosynthesis in pancreatic β-cells
  Sharon S. Zhang, Ergeng Hao, Jianxiu Yu, Wen Liu, Jing Wang, Fred Levine, Gen-Sheng Feng> ;Proceedings of the National Academy of Sciences of the United States of America. 2009 May 5
• 47 citations
  Islet specific Wnt activation in human type II diabetes.
  Seung-Hee Lee, Carla Demeterco, Ifat Geron, Annelie Abrahamsson, Fred Levine, Pamela Itkin-Ansari> ;Experimental Diabetes Research. 2008 Jan 1
• 28 citations
  β-cell regeneration: Neogenesis, replication or both?
  Fred Levine, Pamela Itkin-Ansari> ;Journal of Molecular Medicine. 2008 Mar 1
• 7 citations
  HES6 reverses nuclear reprogramming of insulin-producing cells following cell fusion
  Andrew J. Ball, Annelie Abrahamsson, Björn Tyrberg, Pamela Itkin-Ansari, Fred Levine> ;Biochemical and Biophysical Research Communications. 2007 Apr 6
• 81 citations
  Cryopreservation by slow cooling with DMSO diminished production of Oct-4 pluripotency marker in human embryonic stem cells.
  Igor I. Katkov, Min S. Kim, Ruchi Bajpai, Yoav Altman, Marc Mercola, Jeanne F. Loring, Alexey V. Terskikh, Evan Y. Snyder, Fred Levine> ;Cryobiology. 2006 Oct 1
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