
Frederic G Barr MD PhD
Molecular Genetics, Anatomic Pathology
Senior Investigator and Deputy Chief, Laboratory of Pathology, National Cancer Institute
Join to View Full Profile
3400 Spruce StPhiladelphia, PA 19104
Phone+1 215-662-6503
Fax+1 301-480-0611
Dr. Barr is on Doximity
As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.
- Gain access to free telehealth tools, such as our “call shielding” and one-way patient texting.
- Connect with colleagues in the same hospital or clinic.
- Read the latest clinical news, personalized to your specialty.
Summary
- Dr. Frederic Barr is a physician/scientist based in Bethesda, MD, with subspecialties in molecular and anatomic pathology. He completed his medical education (MD) and graduate education (PhD, Molecular Biology) in 1987 at Washington University in St. Louis School of Medicine. Dr. Barr pursued residency training in Anatomic Pathology at the University of Pennsylvania and post-doctoral training at the Children's Hospital of Philadelphia. Currently, he serves as a Senior Investigator and Deputy Chief of Pathology at the National Cancer Institute and he is also an Adjunct Professor in the Department of Pathology and Laboratory Medicine at the University of Pennsylvania. His research focuses on oncologic pathology, specifically in genetics and epigenetics of the rhabdomyosarcoma family of soft tissue sarcomas. Notably, Dr. Barr was elected to The American Society for Clinical Investigation in 2001, served as the Senior Associate Editor for the Journal of Molecular Diagnostics from 2015 to 2022, and has served on the Soft Tissue Sarcoma Steering Committee of the Children's Oncology Group since 2000.
Education & Training
- Children's Hospital of PhiladelphiaPost-Doctoral Fellowship, 1989 - 1992
- University of PennsylvaniaResidency, 1987 - 1992
- Washington University in St. Louis School of MedicineClass of 1987
- Washington University in St. LouisPhD, Molecular Biology, 1982 - 1986
- Williams CollegeBA, Chemistry, Summa Cum Laude, 1976 - 1980
Certifications & Licensure
- PA State Medical License 1989 - 2026
- American Board of Pathology Anatomic Pathology
Awards, Honors, & Recognition
- Elected Member The American Society for Clinical Investigation, 2001
Publications & Presentations
PubMed
- 1 citationsDNA methylation patterns are influenced by Pax3::Foxo1 expression and developmental lineage in rhabdomyosarcoma tumours forming in genetically engineered mouse models.Wenyue Sun, Stephen M Hewitt, Hollis Wright, Charles Keller, Frederic G Barr
The Journal of Pathology. 2025-03-01 - Novel PAX3::MAML3 Fusion Identified in Alveolar Rhabdomyosarcoma, Using DNA Methylation Profiling to Expand the Genetic Spectrum of "Fusion-Positive" Cases.Josephine K Dermawan, Faizan Malik, John M Gross, Ezra Baraban, Christine Pratilas
Modern Pathology. 2024-11-01 - 6 citationsThe PAX Genes: Roles in Development, Cancer, and Other Diseases.Taryn Shaw, Frederic G Barr, Aykut Üren
Cancers. 2024-02-29
Grant Support
- DNA Methylation-Based Assays For Detecting Disease Spread In RhabdomyosarcomaNational Cancer Institute2010
- COG Studies Of Gene Amplification In RhabdomyosarcomaNational Cancer Institute2005–2009
- Studies Of The T(2;13) Of Alveolar RhabdomyosarcomaNational Cancer Institute2003–2007
- Cancer Molecular Pathology Training ProgramNational Cancer Institute2001–2006
- IRSG Studies Of Alveolar Rhabdomyosarcoma Gene FusionsNational Cancer Institute2001–2005
- Studies Of The T (2;13) Of Alveolar RhabdomyosarcomaNational Cancer Institute2001–2002
- Regulation Of Pax3/Pax7 Expression In RhabdomyosarcomaNational Cancer Institute1997–2001
- Studies Of The (2;13) Of Alveolar RhabdomyosarcomaNational Cancer Institute2000
- T(2--13) Of Alveolar RhabdomyosarcomaNational Cancer Institute1998–1999
- IRSG Laboratory Correlative StudiesNational Cancer Institute1998–1999
- Mechanisms Of Genomic Rearrangement In CarcinogenesisNational Cancer Institute1994–1998
- Alveolar RhabdomyosarcomaNational Cancer Institute1994–1997
Viewing the full profile is available to verified healthcare professionals only.
Find your profile and take control of your online presence: