FrederickEdwardDeweyMD

PubMed

• 1 citations
  Correction to: Early cancer diagnoses through BRCA1/2 screening of unselected adult biobank participants.
  Adam H. Buchanan, Kandamurugu Manickam, Michelle N. Meyer, Jennifer K. Wagner, Miranda L.G. Hallquist, Janet L. Williams, Alanna Kulchak Rahm, Marc S. Williams, Zong M...> ;Genetics in Medicine. 2021 Oct 13
• 76 citations
  Genomics-First Evaluation of Heart Disease Associated With Titin-Truncating Variants.
  Christopher M. Haggerty, Scott M. Damrauer, Michael G. Levin, David Birtwell, David J. Carey, Alicia Golden, Dustin N. Hartzel, Yirui Hu, Renae Judy, Melissa A. Kelly,...> ;Circulation. 2019 Jul 2
• 16 citations
  Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure.
  Pablo Cordero, Victoria N. Parikh, Elizabeth T Chin, Ayca Erbilgin, Michael J. Gloudemans, Ching Shang, Yong Huang, Alex C.Y. Chang, Kevin S. Smith, Frederick Dewey, K...> ;Nature Communications. 2019 Jun 24
• 42 citations
  Cyclin-dependent kinase inhibitor 2B regulates efferocytosis and atherosclerosis.
  Yoko Kojima, Kelly Downing, Ramendra Kundu, Clint Miller, Frederick Dewey, Hope Lancero, Uwe Raaz, Ljubica Perisic, Ulf Hedin, Eric Schadt, Lars Maegdefessel, Tom Quer...> ;The Journal of Clinical Investigation. 2019 May 1
• 40 citations
  Rare Protein-Truncating Variants in APOB, Lower Low-Density Lipoprotein Cholesterol, and Protection Against Coronary Heart Disease.
  Gina M. Peloso, Akihiro Nomura, Amit Khera, Mark Chaffin, Hong-Hee Won, Diego Ardissino, John Danesh, Heribert Schunkert, James G. Wilson, Nilesh J. Samani, Jeanette E...> ;Circulation. Genomic and Precision Medicine. 2019 May 1
• 115 citations
  Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation.
  Seung Hoan Choi, Lu-Chen Weng, Carolina Roselli, Honghuang Lin, Christopher M. Haggerty, M. Benjamin Shoemaker, John Barnard, Dan E. Arking, Daniel I. Chasman, Christi...> ;JAMA. 2018 Dec 11
• 1 citations
  Author Correction: Rare variants in drug target genes contributing to complex diseases, phenome-wide
  Shefali S. Verma, Navya Shilpa Josyula, Anurag Verma, Xinyuan Zhang, Yogasudha Veturi, Frederick E. Dewey, Dustin N. Hartzel, Daniel R. Lavage, Joe Leader, Marylyn D. ...> ;Scientific Reports. 2018 Oct 23
• 39 citations
  Loss-of-Function ABCC8 Mutations in Pulmonary Arterial Hypertension.
  Michael S. Bohnen, Lijiang Ma, Na Zhu, Hongjian Qi, Conor McClenaghan, Claudia Gonzaga-Jauregui, Frederick E. Dewey, John D. Overton, Jeffrey G. Reid, Alan R. Shuldine...> ;Circulation. Genomic and Precision Medicine. 2018 Oct 1
• 374 citations
  Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
  Derek Klarin, Scott M. Damrauer, Kelly Cho, Yan V. Sun, Tanya M. Teslovich, Jacqueline Honerlaw, David R. Gagnon, Scott L. DuVall, Jin Li, Gina M. Peloso, Mark Chaffin...> ;Nature Genetics. 2018 Oct 1
• 137 citations
  Exome Sequencing-Based Screening for BRCA1/2 Expected Pathogenic Variants Among Adult Biobank Participants.
  Kandamurugu Manickam, Adam H. Buchanan, Marci L.B. Schwartz, Miranda L.G. Hallquist, Janet L. Williams, Alanna Kulchak Rahm, Heather Rocha, Juliann M. Savatt, Alyson E...> ;JAMA Network Open. 2018 Sep 7
• 416 citations
  Biobank-driven genomic discovery yields new insight into atrial fibrillation biology
  Jonas B. Nielsen, Rosa B. Thorolfsdottir, Lars G. Fritsche, Weichen Zhou, Morten W. Skov, Sarah E. Graham, Todd J. Herron, Shane McCarthy, Ellen M. Schmidt, Gardar Sve...> ;Nature Genetics. 2018 Jul 30
• 90 citations
  Rare variants in SOX17 are associated with pulmonary arterial hypertension with congenital heart disease
  Na Zhu, Carrie L. Welch, Jiayao Wang, Philip M. Allen, Claudia Gonzaga-Jauregui, Lijiang Ma, Alejandra King, Usha Krishnan, Erika B. Rosenzweig, D. Dunbar Ivy, Eric D....> ;Genome Medicine. 2018 Jul 20
• 84 citations
  Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes
  Viktoria Gusarova, Colm O'Dushlaine, Tanya M. Teslovich, Peter N. Benotti, Tooraj Mirshahi, Omri Gottesman, Cristopher V. Van Hout, Michael F. Murray, Anubha Mahajan, ...> ;Nature Communications. 2018 Jun 13
• 78 citations
  Exome Sequencing in Children With Pulmonary Arterial Hypertension Demonstrates Differences Compared With Adults
  Na Zhu, Claudia Gonzaga-Jauregui, Carrie L. Welch, Lijiang Ma, Hongjian Qi, Alejandra King, Usha Krishnan, Erika B. Rosenzweig, D. Dunbar Ivy, Eric D. Austin, Rizwan H...> ;Circulation. Genomic and Precision Medicine. 2018 Apr 1
• 42 citations
  Early cancer diagnoses through BRCA1/2 screening of unselected adult biobank participants.
  Adam H. Buchanan, Kandamurugu Manickam, Michelle N. Meyer, Jennifer K. Wagner, Miranda L.G. Hallquist, Janet L. Williams, Alanna Kulchak Rahm, Marc S. Williams, Zong M...> ;Genetics in Medicine. 2018 Apr 1
• 452 citations
  A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease
  , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;The New England Journal of Medicine. 2018 Mar 21
• 12 citations
  Rare variants in drug target genes contributing to complex diseases, phenome-wide
  Shefali S. Verma, Navya Shilpa Josyula, Anurag Verma, Xinyuan Zhang, Yogasudha Veturi, Frederick E. Dewey, Dustin N. Hartzel, Daniel R. Lavage, Joe Leader, Marylyn D. ...> ;Scientific Reports. 2018 Mar 15
• 41 citations
  Profiling and Leveraging Relatedness in a Precision Medicine Cohort of 92,455 Exomes.
  Jeffrey Staples, Evan Maxwell, Nehal Gosalia, Claudia Gonzaga-Jauregui, Christopher Snyder, Alicia Hawes, John Penn, Ricardo Ulloa, Xiaodong Bai, Alexander Lopez, Cris...> ;American Journal of Human Genetics. 2018 May 3
• 36 citations
  Genomic diagnostics within a medically underserved population: efficacy and implications.
  Kevin A. Strauss, Claudia Gonzaga-Jauregui, Karlla W. Brigatti, Katie B. Williams, Alejandra King, Cristopher V. Van Hout, Donna L. Robinson, Millie Young, Kavita Prav...> ;Genetics in Medicine. 2018 Jan 1
• 62 citations
  Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development
  Jonas B. Nielsen, Lars G. Fritsche, Wei Zhou, Tanya M. Teslovich, Oddgeir L. Holmen, Stefan Gustafsson, Maiken Elvestad Gabrielsen, Ellen M. Schmidt, Robin N Beaumont,...> ;American Journal of Human Genetics. 2018 Jan 4
• APPLICATIONS OF GENETICS, GENOMICS AND BIOINFORMATICS IN DRUG DISCOVERY.
  Richard Bourgon, Frederick E. Dewey, Zhengyan Kan, Shuyu D Li> ;Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 2018 Jan 1
• 36 citations
  Electronic health record phenotype in subjects with genetic variants associated with arrhythmogenic right ventricular cardiomyopathy: a study of 30,716 subjects with e...
  Christopher M. Haggerty, Cynthia A. James, Hugh Calkins, Crystal Tichnell, Joseph B. Leader, Dustin N. Hartzel, Christopher D. Nevius, Sarah A. Pendergrass, Thomas N. ...> ;Genetics in Medicine. 2017 May 4
• 10 citations
  MAPPIN: a method for annotating, predicting pathogenicity and mode of inheritance for nonsynonymous variants.
  Nehal Gosalia, Aris N. Economides, Frederick E. Dewey, Suganthi Balasubramanian> ;Nucleic Acids Research. 2017 Oct 13
• 56 citations
  Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease.
  Akihiro Nomura, Hong-Hee Won, Amit Khera, Fumihiko Takeuchi, Kaoru Ito, Shane McCarthy, Connor A. Emdin, Derek Klarin, Pradeep Natarajan, Seyedeh M. Zekavat, Namrata G...> ;Circulation Research. 2017 May 15
• 518 citations
  Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease
  Frederick E. Dewey, Viktoria Gusarova, Richard L Dunbar, Colm O'Dushlaine, Claudia Schurmann, Omri Gottesman, Shane McCarthy, Cristopher V. Van Hout, Shannon Bruse, Ha...> ;The New England Journal of Medicine. 2017 May 24
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Journal Articles

• Biobank-Driven Genomic Discovery Yields New Insight into Atrial Fibrillation Biology  
  Frederick E Dewey, Jordan A Shavit, Chad M Brummett, Michael R Mathis, Sachin Kheterpal, Nature
• Rare Variants in SOX17 Are Associated with Pulmonary Arterial Hypertension with Congenital Heart Disease  
  Usha Krishnan, Eric D Austin, Frederick E Dewey, D Dunbar Ivy, Wendy K Chung, Rizwan Hamid, BioMed Central