Frederick L. Ruberg MD (He/Him)

Echocardiography, Cardiothoracic Imaging, Non-Invasive Cardiology

Chief of Cardiovascular Medicine, Boston Medical Center, Boston University Chobanian and Avedisian School of Medicine

732 Harrison AvePreston 3RD floorBoston, MA 02118
Phone+1 617-638-7490
Fax+1 617-414-8742

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Summary

Dr. Frederick Ruberg is a cardiologist in Boston, MA and is affiliated with multiple hospitals in the area, including Boston Medical Center. He received his medical degree from Perelman School of Medicine at the University of Pennsylvania and has been in practice 14 years. He specializes in echocardiography, cardiothoracic imaging, and non-invasive cardiology and is experienced in general cardiology, echocardiography, cardiac ct / mri, and cardiac-gated imaging techniques.

Education & Training

Beth Israel Deaconess Medical CenterFellowship, Cardiovascular Disease, 2004 - 2005
Boston University Medical CenterFellowship, Cardiovascular Disease, 2001 - 2004
Mass General Brigham/Brigham and Women's HospitalResidency, Internal Medicine, 1998 - 2001
Perelman School of Medicine at the University of PennsylvaniaClass of 1998

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Certifications & Licensure

MA State Medical License 2000 - 2027
American Board of Internal Medicine Cardiovascular Disease

Awards, Honors, & Recognition

Fellow (FAHA) American Heart Association
Fellow (FACC) American College of Cardiology

Clinical Trials

Screening for Cardiac Amyloidosis With Nuclear Imaging for Minority Populations Start of enrollment: 2019 May 15
COMPLETED
Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis Start of enrollment: 2023 Sep 19
RECRUITING
Roles: Contact, Principal Investigator

Publications & Presentations

PubMed

Plain language summary of how acoramidis affects the total number of heart problems over time in people with ATTR-CM: findings from the ATTRibute-CM study.
Ahmad Masri, Daniel P Judge, Frederick L Ruberg, Julian D Gillmore, Justin L Grodin
Future Cardiology. 2026-08-03
Evaluating AL-ISS within a BNP-based model for AL amyloidosis in the daratumumab era.
Antonio Berumen, Andrew Staron, Grigorios Kalaitzidis, Omar K Siddiqi, Deepa M Gopal
Blood Advances. 2026-07-14
Quantitative single photon emission computed tomography/computed tomography of Tc-99m-pyrophosphate scans: metrics for short-term risk stratification in transthyretin ...
Mitchell Pleasure, Candace L Jackson, Michelle Castillo, Albert DeLuca, Mona Kinkhabwala
Nuclear Medicine Communications. 2026-07-13

Journal Articles

Early Diagnosis of Cardiac Amyloidosis by Carpal Tunnel Surgery
Frederick L Ruberg, Mathew S Maurer, ScienceDirect
Development and Validation of a Survival Staging System Incorporating BNP in Patients with Light Chain (AL) Amyloidosis
Frederick L Ruberg, Vaishali Sanchorawala, Blood

Authored Content

ACC CardiaCast: Understanding AL and ATTR Cardiac AmyloidosisMarch 2021
Original Research Native T1 and Extracellular Volume in Transthyretin AmyloidosisMarch 2018
More Than Meets the Eye: Time for a New Imaging Paradigm to Test for Cardiac AmyloidosisJanuary 2018

Press Mentions

Transthyretin Cardiac Amyloidosis a Common Cause of HF in Older Black PatientsSeptember 12th, 2025
Transthyretin Cardiac Amyloidosis in Older Black and Hispanic Individuals with Heart FailureSeptember 10th, 2025
2025 HFSA CME Symposium - Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in Patients with Heart Failure: New Opportunities to Improve Patient OutcomesAugust 19th, 2025

Grant Support

Mosaic loss of the Y chromosome in transthyretin (ATTR) cardiac amyloidosisBOSTON MEDICAL CENTER2026–2030
Screening for Cardiac Amyloidosis with a Blood Biomarker in Minority Populations – SCABB-MPUT SOUTHWESTERN MEDICAL CENTER2025–2029
SCAN-MP (Screening for Cardiac Amyloidosiswith Nuclear imaging in Minority Populations)COLUMBIA UNIVERSITY HEALTH SCIENCES2019–2025