GadiLalazarMD

PubMed

• 7 citations
  Oncogenic Addiction of Fibrolamellar Hepatocellular Carcinoma to the Fusion Kinase DNAJB1-PRKACA.
  Christoph Neumayer, Denise Ng, Caroline S Jiang, Adam Qureshi, Gadi Lalazar, Roger Vaughan, Sanford M Simon> ;Clinical Cancer Research. 2023 Jan 4
• 4 citations
  Human hepatocyte PNPLA3-148M exacerbates rapid non-alcoholic fatty liver disease development in chimeric mice.
  Mohammad Kabbani, Eleftherios Michailidis, Sandra Steensels, Clifton G Fulmer, Joseph M Luna, Jérémie Le Pen, Matteo Tardelli, Brandon Razooky, Inna Ricardo-Lax, Chenh...> ;Cell Reports. 2022 Sep 13
• 8 citations
  Targeting BCL-XL in fibrolamellar hepatocellular carcinoma.
  Bassem Shebl, Denise Ng, Gadi Lalazar, Carly Rosemore, Tova M Finkelstein, Rachael D Migler, Guangrong Zheng, Peiyi Zhang, Caroline S Jiang, Adam Qureshi, Roger Vaugha...> ;JCI Insight. 2022 Sep 8
• 6 citations
  Human liver organoids for disease modeling of fibrolamellar carcinoma.
  Nicole J C Narayan, David Requena, Gadi Lalazar, Lavoisier Ramos-Espiritu, Denise Ng, Solomon Levin, Bassem Shebl, Ruisi Wang, William J Hammond, James A Saltsman 3rd,...> ;Stem Cell Reports. 2022 Aug 9
• Mouse characteristics that affect establishing xenografts from hepatocellular carcinoma patient biopsies in the United States.
  Chenhui Zou, Imane El Dika, Koen O A Vercauteren, Marinela Capanu, Joanne Chou, Jinru Shia, Jill Pilet, Corrine Quirk, Gadi Lalazar, Linda Andrus, Mohammad Kabbani, Am...> ;Cancer Medicine. 2022 Feb 1
• 1 citations
  An Interesting Case of Isolated False-Reactive Hepatitis B Surface Antigen.
  Victoria Costa, Zhen Zhao, Sabrina E Racine-Brzostek, Gadi Lalazar, He S. Yang> ;Case Reports in Hepatology. 2021 Jul 19
• 20 citations
  Identification of Novel Therapeutic Targets for Fibrolamellar Carcinoma Using Patient-Derived Xenografts and Direct-from-Patient Screening.
  Gadi Lalazar, David Requena, Lavoisier Ramos-Espiritu, Denise Ng, Patrick Bhola, Ype P. de Jong, Ruisi Wang, Nicole J.C. Narayan, Bassem Shebl, Solomon Levin, Elefther...> ;Cancer Discovery. 2021 Apr 20
• 29 citations
  A Human Organoid Model of Aggressive Hepatoblastoma for Disease Modeling and Drug Testing
  James A. Saltsman, William J. Hammond, Nicole J.C. Narayan, David Requena, Helmuth Gehart, Gadi Lalazar, Michael P. LaQuaglia, Hans Clevers, Sanford M. Simon> ;Cancers. 2020 Sep 18
• 15 citations
  Administration of the Hyper-immune Bovine Colostrum Extract IMM-124E Ameliorates Experimental Murine Colitis.
  Marianne R. Spalinger, Kirstin Atrott, Katharina Baebler, Marlene Schwarzfischer, Hassan Melhem, Dan R Peres, Gadi Lalazar, Gerhard Rogler, Michael Scharl, Isabelle Fr...> ;Journal of Crohn's & Colitis. 2019 May 27
• 25 citations
  PSMD5 inactivation promotes 26S proteasome assembly during colorectal tumor progression
  Avi Levin, Adi Minis, Gadi Lalazar, Jose Rodriguez, Hermann Steller> ;Cancer Research. 2018 Jul 1
• 5 citations
  Intracranial metastasis in fibrolamellar hepatocellular carcinoma.
  William J. Hammond, Gadi Lalazar, James A. Saltsman, Benjamin A. Farber, Enrico Danzer, Tshering C. Sherpa, Charles D. Banda, Jeffrey R. Andolina, Sasan Karimi, Camero...> ;Pediatric Blood & Cancer. 2018 Apr 1
• 41 citations
  Fibrolamellar Carcinoma: Recent Advances and Unresolved Questions on the Molecular Mechanisms.
  Gadi Lalazar, Sanford M. Simon> ;Seminars in Liver Disease. 2018 Feb 1
• 16 citations
  Non coding RNA analysis in fibrolamellar hepatocellular carcinoma
  Benjamin A. Farber, Gadi Lalazar, Elana P. Simon, William J. Hammond, David Requena, Umesh Bhanot, La Quaglia Mp, Sanford M. Simon> ;Oncotarget. 2017 Dec 15
• 97 citations
  DNAJB1–PRKACA fusion kinase interacts with β-catenin and the liver regenerative response to drive fibrolamellar hepatocellular carcinoma
  Edward R. Kastenhuber, Gadi Lalazar, Shauna L. Houlihan, Darjus F. Tschaharganeh, Timour Baslan, Chi-Chao Chen, David Requena, Sha Tian, Benedikt Bosbach, John E. Wilk...> ;Proceedings of the National Academy of Sciences of the United States of America. 2017 Dec 12
• 39 citations
  Autophagy confers resistance to lipopolysaccharide-induced mouse hepatocyte injury
  Gadi Lalazar, Ghulam Ilyas, Shoaib Ahmad Malik, Kun Liu, Enpeng Zhao, Mohammad Amir, Yu Lin, Kathryn E. Tanaka, Mark J. Czaja> ;American Journal of Physiology. Gastrointestinal and Liver Physiology. 2016 Sep 1
• 76 citations
  Transcriptomic characterization of fibrolamellar hepatocellular carcinoma
  Elana P. Simon, Catherine A. Freije, Benjamin A. Farber, Gadi Lalazar, David G. Darcy, Joshua N. Honeyman, Rachel Chiaroni-Clarke, Brian D. Dill, Henrik Molina, Umesh ...> ;Proceedings of the National Academy of Sciences of the United States of America. 2015 Nov 3
• 64 citations
  Oral Administration of OKT3 MAb to Patients with NASH, Promotes Regulatory T-cell Induction, and Alleviates Insulin Resistance: Results of a Phase IIa Blinded Placebo-...
  Gadi Lalazar, Meir Mizrahi, Ilit Turgeman, Tomer Adar, Ami Ben Ya'acov, Yehudit Shabat, Assy Nimer, Nila Hemed, Lidya Zolotarovya, Yoav Lichtenstein, Nadya Lisovoder, ...> ;Journal of Clinical Immunology. 2015 Apr 17
• 320 citations
  Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization
  Kun Liu, Enpeng Zhao, Ghulam Ilyas, Gadi Lalazar, Yu Lin, Muhammad Haseeb, Kathryn E. Tanaka, Mark J. Czaja> ;Autophagy. 2015 Feb 4
• 57 citations
  Oral administration of immunoglobulin G‐enhanced colostrum alleviates insulin resistance and liver injury and is associated with alterations in natural killer T cells
  Tomer Adar, A. Ben Ya'acov, Gadi Lalazar, Yoav Lichtenstein, D. Nahman, Meir Mizrahi, Victor W. Wong, Brian Muller, Grant Rawlin, Yaron Ilan> ;Clinical and Experimental Immunology. 2012 Feb 1
• 19 citations
  Assessment of insulin resistance by a 13C glucose breath test: a new tool for early diagnosis and follow-up of high-risk patients
  Meir Mizrahi, Gadi Lalazar, Tomer Adar, Itamar Raz, Yaron Ilan> ;Nutrition Journal. 2010 May 27
• 60 citations
  Oral Administration of OKT3 Monoclonal Antibody to Human Subjects Induces a Dose-Dependent Immunologic Effect in T Cells and Dendritic Cells
  Yaron Ilan, Ehud Zigmond, Gadi Lalazar, Adi Dembinsky, Ami Ben Ya'acov, Nila Hemed, Ibrahim Kasis, Elizabeth Axelrod, Lidya Zolotarov, Athalia Klein, Madi El Haj, Roop...> ;Journal of Clinical Immunology. 2010 Jan 1
• 13 citations
  Decreased STAT-1 phosphorylation by a thio analogue of beta-D-glucosylceramide is associated with altered NKT lymphocyte polarization.
  Ami Ben Ya'acov, Gadi Lalazar, Dan M. Livovsky, Dimitri Kanovich, Elizabeth Axelrod, Sarah Preston, Guenter Schwarzmann, Yaron Ilan> ;Molecular Immunology. 2009 Oct 8
• 11 citations
  Administration of beta-glycolipids overcomes an unfavorable nutritional dependent host milieu: a role for a soy-free diet and natural ligands in intrahepatic CD8+ lymp...
  Dan M. Livovsky, Gadi Lalazar, Ami Ben Ya'acov, Orit Pappo, Sarah Preston, Lidya Zolotaryova, Yaron Ilan> ;International Immunopharmacology. 2008 Sep 1
• 25 citations
  Modulation of intracellular machinery by β-glycolipids is associated with alteration of NKT lipid rafts and amelioration of concanavalin-induced hepatitis
  Gadi Lalazar, Ami Ben Ya'acov, Adi Lador, Dan M. Livovsky, Orit Pappo, Sarah Preston, Menahem Hareati, Yaron Ilan> ;Molecular Immunology. 2008 Aug 1
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