GailLTorkildsenMD

Ophthalmology • Andover, MA

Physician

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Office
138 Haverhill St
Suite 104
Andover, MA 01810
Phone+1 978-475-0705

Fax+1 978-475-0008
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Education & Training

Icahn School of Medicine at Mount Sinai/New York Eye and Ear Infirmary at Mount SinaiResidency, Ophthalmology, 1994 - 1997
UPMC Medical Education (Pittsburgh)Residency, Surgery, 1992 - 1994
University of Pittsburgh School of MedicineClass of 1992

Certifications & Licensure

FL State Medical License 2002 - 2026
MA State Medical License 1997 - 2025
MD State Medical License 2002 - 2003
American Board of Ophthalmology Ophthalmology

Clinical Trials

Loteprednol Etabonate Opthalmic Suspension for the Treatment of Dry Eye Start of enrollment: 2005 Nov 01
Completed
Phase 2
Evaluation of the Efficacy of Topical Ophthalmic Steroids in a Modified Conjunctival Allergen Challenge (CAC) Model Start of enrollment: 2008 May 01
Completed
Phase 4
Safety and Efficacy Study of Iontophoresis and Dexamethasone Phosphate to Treat Dry Eye Start of enrollment: 2008 Oct 01
Completed
Phase 2
Safety and Efficacy Study of RX-10045 on the Signs and Symptoms of Dry Eye Start of enrollment: 2008 Nov 01
Completed
Phase 2
Evaluation of the Safety and Efficacy of Ketotifen 4.0% Patch as Compared to Placebo Patch, Olopatadine 0.2% Ophthalmic Solution, and Artificial Tears in the Conjunctival Allergen Challenge (CAC) Model of Acute Allergic Conjunctivitis Start of enrollment: 2009 Feb 01
Completed
Phase 2
Efficacy Study to Evaluate the Effectiveness of 3 Concentrations of SAR 1118 in Allergic Conjunctivitis Start of enrollment: 2009 Apr 24
Completed
Phase 2
A Study Evaluating the Efficacy of SAR 1118 (0.1%, 1.0%, 5.0%) Ophthalmic Solution in Subjects With Dry Eye Conducted in a Controlled Adverse Environment (CAE) Start of enrollment: 2009 Aug 03
Completed
Phase 2
A Pilot Study of the Safety of MC-1101 in Both Normal Volunteers and Patients With Early Dry AMD Start of enrollment: 2009 Aug 01
Completed
Phase 1
Safety and Efficacy Study of EGP-437 (Dexamethasone Phosphate Formulated for Ocular Iontophoresis) to Treat Dry Eye Start of enrollment: 2010 Jun 01
Completed
Phase 3
Safety and Efficacy Study of MIM-D3 Ophthalmic Solution for the Treatment of Dry Eye Start of enrollment: 2010 Nov 01
Completed
Phase 2
Evaluation of Prednisolone in a Modified Conjunctival Allergen Challenge Model Start of enrollment: 2012 Nov 01
Completed
Phase 4
A Phase 2, Open-Label, Randomized, Parallel Group, Placebo-Controlled, Single-Center Study to Assess Anti-microbial Efficacy and Safety of DCN01 Compared to Unisol® Following Topical Periocular Administration in Healthy Volunteers Start of enrollment: 2013 Apr 01
Completed
Phase 2
Safety and Efficacy of PG101 for Dry Eye Syndrome Start of enrollment: 2013 Dec 01
Completed
Phase 1, Phase 2
A Clinical Study to Assess the Safety and Efficacy of an Ophthalmic Solution (SkQ1) in the Treatment of Dry Eye Syndrome (DES) Start of enrollment: 2014 Apr 01
Completed
Phase 2
Efficacy and Safety of XG-104 for the Treatment of Dry Eye Start of enrollment: 2014 Sep 01
Completed
Phase 2
Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome : ARISE-2 Start of enrollment: 2016 Nov 01
Completed
Phase 3
A Study to Assess Efficacy of HL036 in Subjects With Dry Eyes Start of enrollment: 2017 Nov 05
Completed
Phase 2
Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome: ARISE-3 Start of enrollment: 2019 May 24
Completed
Phase 3
Evaluation of the Safety and Pharmacokinetics of Brimonidine Tartrate 0.025%/Ketotifen Fumarate 0.035% Combination Ophthalmic Solution Start of enrollment: 2023 Apr 20
Completed
Roles: Contact
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Publications & Presentations

PubMed

1 citations
Efficacy and Safety of the Melanocortin Pan-Agonist PL9643 in a Phase 2 Study of Patients with Dry Eye Disease.
David Evans, Kenneth Kenyon, George Ousler, Michael Watson, Patrick Vollmer, Eugene B McLaurin, Gail Torkildsen, Jason Winters, John Dodd, Robert Jordan, Stephen T Wil...> ;Journal of Ocular Pharmacology and Therapeutics. 2023 Nov 1
19 citations
ONSET-1 Phase 2b Randomized Trial to Evaluate the Safety and Efficacy of OC-01 (Varenicline Solution) Nasal Spray on Signs and Symptoms of Dry Eye Disease.
David Wirta, Gail L Torkildsen, Blair Boehmer, David A Hollander, Edward Bendert, Lijuan Zeng, Michael Ackermann, Jeffrey Nau> ;Cornea. 2022 Oct 1
3 citations
Efficacy and Safety of Single-dose OC-02 (Simpinicline Solution) Nasal Spray on Signs and Symptoms of Dry Eye Disease: The PEARL Phase II Randomized Trial.
Gail L Torkildsen, Guruprasad R Pattar, Gary Jerkins, Kristen Striffler, Jeffrey Nau> ;Clinical Therapeutics. 2022 Sep 1
9 citations
Symptom improvement in dry eye subjects following intranasal tear neurostimulation: Results of two studies utilizing a controlled adverse environment
Guruprasad R. Pattar, Gary Jerkins, David G. Evans, Gail Torkildsen, George W Ousler, David A Hollander, Mark Holdbrook, Michelle Senchyna> ;The Ocular Surface. 2020 Apr 1
27 citations
Management of Ocular Allergy Itch With an Antihistamine-Releasing Contact Lens.
Brian Pall, Paul J Gomes, Frank Yi, Gail Torkildsen> ;Cornea. 2019 Jun 1
10 citations
Low-dose brimonidine for relief of ocular redness: integrated analysis of four clinical trials.
Stacey L Ackerman, Gail Torkildsen, Eugene B McLaurin, Jason L Vittitow> ;Clinical & Experimental Optometry. 2019 Mar 1
10 citations
Safety of cetirizine ophthalmic solution 0.24% for the treatment of allergic conjunctivitis in adult and pediatric subjects
Ranjan P. Malhotra, E. J. Meier, Gail Torkildsen, Paul J Gomes, Mark C Jasek> ;Clinical Ophthalmology. 2019 Feb 19
11 citations
A phase 2 randomized, double-masked, placebo-controlled study of novel nonsystemic kinase inhibitor TOP1630 for the treatment of dry eye disease.
Michael D. Taylor, George W Ousler, Gail Torkildsen, Claire A. Walshe, Matthew C. Fyfe, Adele Rowley, Steve Webber, John D. Sheppard, Ajay Duggal> ;Clinical Ophthalmology. 2019 Feb 12
36 citations
A Clinical Phase II Study to Assess Efficacy, Safety, and Tolerability of Waterfree Cyclosporine Formulation for Treatment of Dry Eye Disease.
David Wirta, Gail Torkildsen, Helen R. Moreira, John D. Lonsdale, Joseph B. Ciolino, Garrit Jentsch, Michael Beckert, George W Ousler, Philipp Steven, Sonja Krösser> ;Ophthalmology. 2019 Jan 28
20 citations
Characterization of tear production in subjects with dry eye disease during intranasal tear neurostimulation: Results from two pivotal clinical trials.
John D. Sheppard, Gail Torkildsen, Joel A. Geffin, Jung Dao, David G. Evans, George W Ousler, Jasmine Wilson, Stephanie N. Baba, Michelle Senchyna, Edward J. Holland> ;The Ocular Surface. 2019 Jan 1
6 citations
Phase III trials examining the efficacy of cetirizine ophthalmic solution 0.24% compared to vehicle for the treatment of allergic conjunctivitis in the conjunctival al...
E. J. Meier, Gail Torkildsen, Paul J Gomes, Mark C Jasek> ;Clinical Ophthalmology. 2018 Dec 13
9 citations
Evaluation of Efficacy and Safety of Brimonidine Tartrate Ophthalmic Solution, 0.025% for Treatment of Ocular Redness.
Gail Torkildsen, Christine M Sanfilippo, Heleen H DeCory, Paul J Gomes> ;Current Eye Research. 2018 Jan 1
12 citations
Evaluation of a new artificial tear formulation for the management of tear film stability and visual function in patients with dry eye.
Gail Torkildsen, Mile Brujic, Michael S Cooper, Paul M. Karpecki, Parag A. Majmudar, William Trattler, Meryl Reis, Joseph B. Ciolino> ;Clinical Ophthalmology. 2017 Oct 19
4 citations
Pooled analysis of two studies evaluating efficacy and safety of olopatadine hydrochloride 0.77% in patients with allergic conjunctivitis
Eugene B McLaurin, M.T. Bergmann, Abhijit Narvekar, Adeniyi Adewale, Paul J Gomes, Gail Torkildsen> ;Clinical Ophthalmology. 2017 Jun 8
13 citations
Vehicle-Controlled, Phase 2 Clinical Trial of a Sustained-Release Dexamethasone Intracanalicular Insert in a Chronic Allergen Challenge Model
Gail Torkildsen, Mark B. Abelson, Paul J Gomes, Eugene McLaurin, Susan L Potts, Francis S. Mah> ;Journal of Ocular Pharmacology and Therapeutics. 2017 Mar 1
25 citations
The IMPACT study: a prospective evaluation of the effects of cyclosporine ophthalmic emulsion 0.05% on ocular surface staining and visual performance in patients with ...
Karl G Stonecipher, Gail Torkildsen, George W Ousler, Scot Morris, Linda Villanueva, David A Hollander> ;Clinical Ophthalmology. 2016 May 13
Safety and comfort evaluation of a new formulation of Visine® lubricant eye drops containing HydroBlend™ and GentlePur™
Gail Torkildsen, Sherryl Frisch, Mingqi Bai, Louis Gentner, Uday Doshi, Jane Zhang> ;Clinical Ophthalmology. 2016 Feb 19
16 citations
Efficacy and safety of olopatadine hydrochloride 0.77% in patients with allergic conjunctivitis using a conjunctival allergen-challenge model.
Gail Torkildsen, Abhijit Narvekar, M.T. Bergmann> ;Clinical Ophthalmology. 2015 Sep 14
137 citations
Lifitegrast Ophthalmic Solution 5.0% for Treatment of Dry Eye Disease: Results of the OPUS-1 Phase 3 Study
John D. Sheppard, Gail Torkildsen, John Lonsdale, Francis A. D'Ambrosio, Eugene B McLaurin, Richard A. Eiferman, Kathryn S. Kennedy, Charles P. Semba> ;Ophthalmology. 2014 Feb 1
76 citations
A phase 2 randomized, double-masked, placebo-controlled study of a novel integrin antagonist (SAR 1118) for the treatment of dry eye.
Charles P. Semba, Gail Torkildsen, John Lonsdale, Eugene B McLaurin, Joel A. Geffin, Thomas K. Mundorf, Kathryn S. Kennedy, George W Ousler> ;American Journal of Ophthalmology. 2012 Jun 1
7 citations
Integrated phase III trials of bepotastine besilate ophthalmic solution 1.5% for ocular itching associated with allergic conjunctivitis.
E. J. Meier, Gail Torkildsen, James A. Gow, Timothy R. McNamara, Paul J Gomes, Jon Williams> ;Allergy and Asthma Proceedings. 2012 May 1
12 citations
Prolonged Effectiveness of Bepotastine Besilate Ophthalmic Solution for the Treatment of Ocular Symptoms of Allergic Conjunctivitis
J.I. Williams, Kathryn S. Kennedy, James A. Gow, Gail Torkildsen, Mark B. Abelson, Paul J Gomes> ;Journal of Ocular Pharmacology and Therapeutics. 2011 Aug 2
61 citations
Ocular iontophoresis of EGP-437 (dexamethasone phosphate) in dry eye patients: results of a randomized clinical trial.
Michael A. Patane, Amy E. Cohen, Stephen From, Gail Torkildsen, Donna Welch, George W Ousler> ;Clinical Ophthalmology. 2011 May 15
16 citations
The safety and efficacy of alcaftadine 0.25% ophthalmic solution for the prevention of itching associated with allergic conjunctivitis.
Gail Torkildsen, Arthur Shedden> ;Current Medical Research and Opinion. 2011 Feb 14
24 citations
Evaluation of clinical efficacy and safety of tobramycin/dexamethasone ophthalmic suspension 0.3%/0.05% compared to azithromycin ophthalmic solution 1 % in the treatme...
Gail L Torkildsen, Paul Cockrum, E. J. Meier, William M Hammonds, Bruce Silverstein, Steven M Silverstein> ;Current Medical Research and Opinion. 2011 Jan 1
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Press Mentions

China’s Professor Lixin Xie Leads Dry Eye Treatment Study at Qingdao Eye HospitalOctober 15th, 2019
Novaliq Announces Last Patient Enrolled in Phase 2 Clinical Trial of CyclASol® for the Treatment of Moderate to Severe Dry Eye DiseaseMay 6th, 2016
Pour Le Traitement Du Syndrome De L'oeil Sec Modéré à GraveMay 6th, 2016