GaneshVenkataraman(Venkataraman)RajMD

PubMed

• ZNF397 Deficiency Triggers TET2-driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer.
  Yaru Xu, Yuqiu Yang, Zhaoning Wang, Martin Sjostrom, Yuyin Jiang, Yitao Tang, Siyuan Cheng, Su Deng, Choushi Wang, Julisa Gonzalez, Nickolas A Johnson, Xiang Li, Xiaol...> ;Cancer Discovery. 2024 Apr 8
• UBE2J1 is the E2 ubiquitin-conjugating enzyme regulating androgen receptor degradation and antiandrogen resistance.
  Carla Rodriguez Tirado, Choushi Wang, Xiaoling Li, Su Deng, Julisa Gonzalez, Nickolas A Johnson, Yaru Xu, Lauren A Metang, Medha Sundar Rajan, Yuqiu Yang, Yi Yin, Mia ...> ;Oncogene. 2024 Jan 1
• Evaluating physiochemical properties of FDA-approved orally administered drugs.
  Tanner C Reese, Anvita Devineni, Tristan Smith, Ismail Lalami, Jung-Mo Ahn, Ganesh V Raj> ;Expert Opinion on Drug Discovery. 2024 Feb 1
• 1 citations
  Transposable Elements Are Co-opted as Oncogenic Regulatory Elements by Lineage-Specific Transcription Factors in Prostate Cancer.
  Giacomo Grillo, Tina Keshavarzian, Simon Linder, Christopher Arlidge, Lisanne Mout, Ankita Nand, Mona Teng, Aditi Qamra, Stanley Zhou, Ken J Kron, Alex Murison, James ...> ;Cancer Discovery. 2023 Nov 1
• 3 citations
  Riluzole Suppresses Growth and Enhances Response to Endocrine Therapy in ER+ Breast Cancer.
  Ayodeji O Olukoya, Hillary Stires, Shaymaa Bahnassy, Sonali Persaud, Yanira Guerra, Suman Ranjit, Shihong Ma, M Idalia Cruz, Carlos Benitez, Aaron M Rozeboom, Hannah C...> ;Journal of the Endocrine Society. 2023 Aug 28
• 6 citations
  Loss of SYNCRIP unleashes APOBEC-driven mutagenesis, tumor heterogeneity, and AR-targeted therapy resistance in prostate cancer.
  Xiaoling Li, Yunguan Wang, Su Deng, Guanghui Zhu, Choushi Wang, Nickolas A Johnson, Zeda Zhang, Carla Rodriguez Tirado, Yaru Xu, Lauren A Metang, Julisa Gonzalez, Atre...> ;Cancer Cell. 2023 Aug 14
• 1 citations
  Critical role of antioxidant programs in enzalutamide-resistant prostate cancer.
  Eliot B Blatt, Karla Parra, Antje Neeb, Lorenzo Buroni, Denisa Bogdan, Wei Yuan, Yunpeng Gao, Collin Gilbreath, Alec Paschalis, Suzanne Carreira, Ralph J DeBerardinis,...> ;Oncogene. 2023 Jul 1
• 7 citations
  Testosterone and the Androgen Receptor.
  Thomas Gerald, Ganesh Raj> ;The Urologic Clinics of North America. 2022 Nov 1
• 5 citations
  A First-in-Class Inhibitor of ER Coregulator PELP1 Targets ER+ Breast Cancer.
  Kristin A Altwegg, Suryavathi Viswanadhapalli, Monica Mann, Dimple Chakravarty, Samaya Krishnan, Zexuan Liu, Junhao Liu, Uday P Pratap, Behnam Ebrahimi, John R Sanchez...> ;Cancer Research. 2022 Oct 17
• 1 citations
  Author Correction: Ectopic JAK-STAT activation enables the transition to a stem-like and multilineage state conferring AR-targeted therapy resistance.
  Su Deng, Choushi Wang, Yunguan Wang, Yaru Xu, Xiaoling Li, Nickolas A Johnson, Atreyi Mukherji, U-Ging Lo, Lingfan Xu, Julisa Gonzalez, Lauren A Metang, Jianfeng Ye, C...> ;Nature Cancer. 2022 Oct 1
• 2 citations
  Emerging hormonal agents for the treatment of prostate cancer.
  Sam Gold, Ganesh V Raj, Bochner, E.> ;Expert Opinion on Emerging Drugs. 2022 Sep 1
• 35 citations
  Ectopic JAK-STAT activation enables the transition to a stem-like and multilineage state conferring AR-targeted therapy resistance.
  Su Deng, Choushi Wang, Yunguan Wang, Yaru Xu, Xiaoling Li, Nickolas A Johnson, Atreyi Mukherji, U-Ging Lo, Lingfan Xu, Julisa Gonzalez, Lauren A Metang, Jianfeng Ye, C...> ;Nature Cancer. 2022 Sep 1
• 4 citations
  Targeting ESR1 mutation-induced transcriptional addiction in breast cancer with BET inhibition.
  Sm N Udden, Qian Wang, Sunil Kumar, Venkat S Malladi, Shwu-Yuan Wu, Shuguang Wei, Bruce A Posner, Sophie Geboers, Noelle S Williams, Yulun Liu, Jayesh K Sharma, Ram S ...> ;JCI Insight. 2022 Sep 8
• 8 citations
  Targeting LIPA independent of its lipase activity is a therapeutic strategy in solid tumors via induction of endoplasmic reticulum stress.
  Xihui Liu, Suryavathi Viswanadhapalli, Shourya Kumar, Tae-Kyung Lee, Andrew Moore, Shihong Ma, Liping Chen, Michael Hsieh, Mengxing Li, Gangadhara R Sareddy, Karla Par...> ;Nature Cancer. 2022 Jul 1
• 4 citations
  Enrichment of "Cribriform" morphologies (intraductal and cribriform adenocarcinoma) and genomic alterations in radiorecurrent prostate cancer.
  Rajal B Shah, Doreen N Palsgrove, Neil B Desai, Jeffrey Gagan, Amanda Mennie, Ganesh Raj, Raquibul Hannan> ;Modern Pathology. 2022 Oct 1
• 5 citations
  Targeting radioresistance and replication fork stability in prostate cancer.
  Xiangyi Li, GuemHee Baek, Suzanne Carreira, Wei Yuan, Shihong Ma, Mia Hofstad, Sora Lee, Yunpeng Gao, Claudia Bertan, Maria de Los Dolores Fenor de la Maza, Prasanna G...> ;JCI Insight. 2022 May 9
• 8 citations
  The central role of Sphingosine kinase 1 in the development of neuroendocrine prostate cancer (NEPC): A new targeted therapy of NEPC.
  Cheng-Fan Lee, Yu-An Chen, Elizabeth Hernandez, Rey-Chen Pong, Shihong Ma, Mia Hofstad, Payal Kapur, Haiyen Zhau, Leland Wk Chung, Chih-Ho Lai, Ho Lin, Ming-Shyue Lee,...> ;Clinical and Translational Medicine. 2022 Feb 1
• 7 citations
  Poly-glutamine-dependent self-association as a potential mechanism for regulation of androgen receptor activity.
  Carlos M Roggero, Victoria Esser, Lingling Duan, Allyson M Rice, Shihong Ma, Ganesh V Raj, Michael K Rosen, Zhi-Ping Liu, Josep Rizo> ;Plos One. 2022 Jan 5
• Alterations in BRCA2 as Determinants of Therapy Response in Prostate Cancer.
  Mia Hofstad, Emily Y Huang, Andrea Woods, Yi Yin, Neil B Desai, Ganesh V Raj> ;Critical Reviews in Oncogenesis. 2022 Jan 1
• 1 citations
  Dose-Intensified Stereotactic Ablative Radiation for Localized Prostate Cancer.
  Lily Chen, Bhavani S Gannavarapu, Neil B Desai, Michael R Folkert, Michael Dohopolski, Ang Gao, Chul Ahn, Jeffrey Cadeddu, Aditya Bagrodia, Solomon Woldu, Ganesh V Raj...> ;Frontiers in Oncology. 2022 Jan 1
• 9 citations
  Validation of SV2A-Targeted PET Imaging for Noninvasive Assessment of Neuroendocrine Differentiation in Prostate Cancer.
  Bing Guan, Ning Zhou, Cheng-Yang Wu, Songye Li, Yu-An Chen, Sashi Debnath, Mia Hofstad, Shihong Ma, Ganesh V Raj, Dalin He, Jer-Tsong Hsieh, Yiyun Huang, Guiyang Hao, ...> ;International Journal of Molecular Sciences. 2021 Dec 3
• 7 citations
  Stereotactic Ablative Radiotherapy for High-Risk Prostate Cancer-a Prospective Multi-level MRI-based Dose Escalation Trial.
  Raquibul Hannan, Samer Salamekh, Neil Desai, Aurelie Garant, Michael R. Folkert, Daniel N. Costa, Samantha Mannala, Chul Ahn, Osama Mohamad, Aaron Laine, Dong W. Natha...> ;International Journal of Radiation Oncology, Biology, Physics. 2021 Nov 10
• 10 citations
  LIFR inhibition enhances the therapeutic efficacy of HDAC inhibitors in triple negative breast cancer.
  Mengxing Li, Suryavathi Viswanadhapalli, Bindu Santhamma, Uday P. Pratap, Yiliao Luo, Junhao Liu, Kristin A. Altwegg, Weiwei Tang, Zexuan Liu, Xiaonan Li, Behnam Ebrah...> ;Communications Biology. 2021 Oct 29
• 2 citations
  Synthesis and fluorine-18 radiolabeling of a phospholipid as a PET imaging agent for prostate cancer.
  Kim H. Kwan, Ingrid Burvenich, Margaret M. Centenera, Yit Wooi Goh, Angela Rigopoulos, Jonas Dehairs, Johannes V. Swinnen, Ganesh V. Raj, Andrew J. Hoy, Lisa M. Butler...> ;Nuclear Medicine and Biology. 2021 Feb 1
• 3 citations
  Dynamic differences between DNA damage repair responses in primary tumors and cell lines
  Collin Gilbreath, Shihong Ma, Lan Yu, Rajni Sonavane, Carlos M. Roggero, Anvita Devineni, Ryan Mauck, Neil Desai, Aditya Bagrodia, Ralf Kittler, Ganesh V. Raj, Yi Yin> ;Translational Oncology. 2021 Jan 1
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Journal Articles

• Alternative Splicing in Prostate Cancer  
  Ganesh V Raj, Stephen R Plymate, Nature