GaryEBrandtMD

PubMed

• Design, synthesis, and evaluation of efflux substrate-metal chelator conjugates as potential antimicrobial agents.
  Zhang Y, Eric Ballard C, Zheng S, Gao X, Ko K, Yang H, Brandt G, Lou X, Tai PC, Lu C, Wang B> ;Bioorg. Med. Chem. Lett.. 2007-02-01
• Engineering an antibiotic to fight cancer: optimization of the novobiocin scaffold to produce anti-proliferative agents.
  Zhao, H., Donnelly, A. C., Kusuma, B. R., Brandt, G. E., Brown, D., Rajewski, R. A., Vielhauer, G., Holzbeierlein, J., Cohen, M. S., Blagg, B. S.> ;J Med Chem. 2011 Jun 9
• Identification and initial SAR of silybin: an Hsp90 inhibitor.
  Zhao, H., Brandt, G. E., Galam, L., Matts, R. L., Blagg, B. S.> ;Bioorg Med Chem Lett. 2011 May 1
• A systematic protocol for the characterization of Hsp90 modulators.
  Matts, R. L., Brandt, G. E., Lu, Y., Dixit, A., Mollapour, M., Wang, S., Donnelly, A. C., Neckers, L., Verkhivker, G., Blagg, B. S.> ;Bioorg Med Chem. 2011 Jan 1
• Alternate strategies of Hsp90 modulation for the treatment of cancer and other diseases.
  Brandt, G. E., Blagg, B. S.> ;Curr Top Med Chem. 2009 Oct 29
• Design, synthesis, and biological evaluation of conformationally constrained cis-amide Hsp90 inhibitors.
  Duerfeldt, A. S., Brandt, G. E., Blagg, B. S.> ;Org Lett. 2009 Jun 04
• Gedunin, a novel hsp90 inhibitor: semisynthesis of derivatives and preliminary structure-activity relationships.
  Brandt, G. E., Schmidt, M. D., Prisinzano, T. E., Blagg, B. S.> ;J Med Chem. 2008 Oct 23
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