GaryP. H.HoMDPhD

PubMed

• 1 citations
  Increased palmitoylation improves estrogen receptor alpha-dependent hippocampal synaptic deficits in a mouse model of synucleinopathy.
  Tim E Moors, Shaomin Li, Thomas D McCaffery, Gary P H Ho, Pascal A Bechade, Luu N Pham, Maria Ericsson, Silke Nuber> ;Science Advances. 2023 Nov 15
• 7 citations
  Palmitoylation of the Parkinson's disease-associated protein synaptotagmin-11 links its turnover to α-synuclein homeostasis.
  Gary P H Ho, Erin C Wilkie, Andrew J White, Dennis J Selkoe> ;Science Signaling. 2023 Feb 14
• 16 citations
  Upregulation of Cellular Palmitoylation Mitigates α-Synuclein Accumulation and Neurotoxicity.
  Gary P.H. Ho, Nagendran Ramalingam, Thibaut Imberdis, Erin C. Wilkie, Ulf Dettmer, Dennis J. Selkoe> ;Movement Disorders. 2021 Feb 1
• 116 citations
  S-nitrosylation and S-palmitoylation reciprocally regulate synaptic targeting of PSD-95.
  Gary P.H. Ho, Balakrishnan Selvakumar, Jun Mukai, Lynda D. Hester, Yuxuan Wang, Joseph A. Gogos, Solomon H. Snyder> ;Neuron. 2011 Jul 14
• Correction to: Clinical trial-ready patient cohorts for multiple system atrophy: coupling biospecimen and iPSC banking to longitudinal deep-phenotyping.
  Alain Ndayisaba, Ariana T Pitaro, Andrew S Willett, Kristie A Jones, Claudio Melo de Gusmao, Abby L Olsen, Jisoo Kim, Eero Rissanen, Jared K Woods, Sharan R Srinivasan...> ;Cerebellum. 2024 Feb 1
• 2 citations
  Clinical Trial-Ready Patient Cohorts for Multiple System Atrophy: Coupling Biospecimen and iPSC Banking to Longitudinal Deep-Phenotyping.
  Alain Ndayisaba, Ariana T Pitaro, Andrew S Willett, Kristie A Jones, Claudio Melo de Gusmao, Abby L Olsen, Jisoo Kim, Eero Rissanen, Jared K Woods, Sharan R Srinivasan...> ;Cerebellum. 2024 Feb 1
• 5 citations
  Lipase regulation of cellular fatty acid homeostasis as a Parkinson's disease therapeutic strategy.
  Saranna Fanning, Haley Cirka, Jennifer L Thies, Jooyoung Jeong, Sarah M Niemi, Joon Yoon, Gary P H Ho, Julian A Pacheco, Ulf Dettmer, Lei Liu, Clary B Clish, Kevin J H...> ;NPJ Parkinson's Disease. 2022 Jun 9
• 88 citations
  Phosphorylation of FANCD2 on two novel sites is required for mitomycin C resistance.
  Gary P.H. Ho, Steven P. Margossian, Toshiyasu Taniguchi, Alan D. D'Andrea> ;Molecular and Cellular Biology. 2006 Sep 15
• 15 citations
  Rapid Alpha-Synuclein Toxicity in a Neural Cell Model and Its Rescue by a Stearoyl-CoA Desaturase Inhibitor.
  Elizabeth Terry-Kantor, Arati Tripathi, Thibaut Imberdis, Zachary M LaVoie, Gary P.H. Ho, Dennis J. Selkoe, Saranna Fanning, Nagendran Ramalingam, Ulf Dettmer> ;International Journal of Molecular Sciences. 2020 Jul 22
• 54 citations
  Cell models of lipid-rich α-synuclein aggregation validate known modifiers of α-synuclein biology and identify stearoyl-CoA desaturase.
  Thibaut Imberdis, Joseph Negri, Nagendran Ramalingam, Elizabeth Terry-Kantor, Gary P.H. Ho, Saranna Fanning, Georgia L. Stirtz, Tae-Eun Kim, Oren A. Levy, Tracy L. You...> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Oct 8
• 150 citations
  Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment
  , , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;Molecular Cell. 2019 Mar 7
• Clinical Reasoning: A 58-year-old woman with loss of vision in her left eye
  Gary P.H. Ho, Kate Brizzi, David Meredith, Edward R. Laws, Aaron L. Berkowitz> ;Neurology. 2016 Mar 8
• 29 citations
  Dexras1 mediates glucocorticoid-associated adipogenesis and diet-induced obesity
  Jiyoung Y. Cha, Hyo Jung Kim, Jung Hwan Yu, Jing Xu, Daham Kim, Bindu D. Paul, Hyeonjin Choi, Seyun Kim, Yoo Jeong Lee, Gary P.H. Ho, Feng Rao, Solomon H. Snyder, Jae ...> ;Proceedings of the National Academy of Sciences of the United States of America. 2013 Dec 17
• 103 citations
  Nitric oxide S-nitrosylates serine racemase, mediating feedback inhibition of D-serine formation.
  Asif K. Mustafa, Manish Kumar, Balakrishnan Selvakumar, Gary P.H. Ho, Jeffrey T. Ehmsen, Roxanne K. Barrow, L. Mario Amzel, Solomon H. Snyder> ;Proceedings of the National Academy of Sciences of the United States of America. 2007 Feb 20
• 79 citations
  DNA damage responses and their many interactions with the replication fork.
  Paul R. Andreassen, Gary P.H. Ho, Alan D. D'Andrea> ;Carcinogenesis. 2006 May 1
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Books/Book Chapters

• Restless Legs Syndrome/Willis Ekbom Disease 
  Chapter: Impulsive Behaviors: Definition, Prevalence, Neurobiology, and Management 
  Gary P. H. Ho, Charlene E. Gamaldo, Seema Gulyani, Rachel E. SalasEditors: Mauro Manconi and Diego García-Borreguero.2017