GaryAlanSilvermanMD

PubMed

• 10 citations
  Functional characterization of four ATP-binding cassette transporter A3 gene (ABCA3) variants
  June Y. Hu, Ping Yang, Daniel J. Wegner, Hillary B. Heins, Cliff J. Luke, Fuhai Li, Frances V. White, Gary A. Silverman, F. Sessions Cole, Jennifer A. Wambach> ;Human Mutation. 2020 Jul 1
• 14 citations
  Mechanisms of Action of Autophagy Modulators Dissected by Quantitative Systems Pharmacology Analysis
  Qingya Shi, Fen Pei, Gary A. Silverman, Stephen C. Pak, David H. Perlmutter, Bing Liu, Ivet Bahar> ;International Journal of Molecular Sciences. 2020 Apr 19
• 30 citations
  Autophagy genes in myeloid cells counteract IFNγ-induced TNF-mediated cell death and fatal TNF-induced shock.
  Anthony Orvedahl, Michael R. McAllaster, Amy Sansone, Bria F. Dunlap, Chandni Desai, Ya-Ting Wang, Dale R. Balce, Cliff J. Luke, Sanghyun Lee, Robert C. Orchard, Maxim...> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Aug 13
• 8 citations
  CemOrange2 fusions facilitate multifluorophore subcellular imaging in C. elegans
  Brian J. Thomas, Ira E. Wight, Wendy Yen Yun Chou, Marco Moreno, Zachary Dawson, Arielle L. Homayouni, Huiyan Huang, Hyori Kim, Hanna Jia, Justin R. Buland, Jennifer A...> ;Plos One. 2019 Mar 26
• 14 citations
  An analog of glibenclamide selectively enhances autophagic degradation of misfolded α1-antitrypsin Z
  Yan Wang, Murat Can Cobanoglu, Jie Li, Tunda Hidvegi, Pamela Hale, Andrew S. Chu, Zhenwei Gong, Radhika Muzumdar, Gary A. Silverman, Ivet Bahar, David H. Perlmutter, > ;Plos One. 2019 Jan 23
• 40 citations
  Serum squamous cell carcinoma antigen as an early indicator of response during therapy of cervical cancer.
  Stephanie Markovina, Songyan Wang, Lauren E. Henke, Cliff J. Luke, Stephen C. Pak, Todd DeWees, John D. Pfeifer, Julie K. Schwarz, Weijun Liu, Shuai Chen, David G. Mut...> ;British Journal of Cancer. 2018 Jan 1
• 30 citations
  Quantitative assessment of cell fate decision between autophagy and apoptosis
  Bing Liu, Zoltán N. Oltvai, Hülya Bayır, Gary A. Silverman, Stephen C. Pak, David H. Perlmutter, Ivet Bahar> ;Scientific Reports. 2017 Dec 14
• 9 citations
  Activation of the Caenorhabditis elegans Degenerin Channel by Shear Stress Requires the MEC-10 Subunit.
  Shujie Shi, Cliff J. Luke, Gary A. Silverman, Thomas R. Kleyman> ;The Journal of Biological Chemistry. 2016 Jul 1
• 673 citations
  Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
  Vyas, J. M., Daniel J Klionsky, Kotb Abdelmohsen, Akihisa Abe, Md Joynal Abedin, Hagai Abeliovich, Abraham Acevedo Arozena, Hiroaki Adachi, Christopher M Adams, Peter ...> ;Autophagy. 2016 Jan 1
• 6 citations
  High-Throughput, Liquid-Based Genome-Wide RNAi Screening in C. elegans.
  Linda P. O’Reilly, Ryan R. Knoerdel, Gary A. Silverman, Stephen C. Pak> ;Methods in Molecular Biology. 2016 Jan 1
• 50 citations
  Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356
  Daniel J. Klionsky, Kotb Abdelmohsen, Akihisa Abe, Joynal Abedin, Hagai Abeliovich, Abraham Acevedo Arozena, Hiroaki Adachi, Christopher M. Adams, Peter D. Adams, Khos...> ;Autophagy. 2016 Jan 1
• 21 citations
  Enhancing autophagy with drugs or lung-directed gene therapy reverses the pathological effects of respiratory epithelial cell proteinopathy
  Tunda Hidvegi, Donna B. Stolz, John F. Alcorn, Samuel A. Yousem, Jieru Wang, Adriana S. Leme, A. McGarry Houghton, Pamela Hale, Michael Ewing, Houming Cai, Evelyn Akpa...> ;The Journal of Biological Chemistry. 2015 Dec 11
• 10 citations
  SERPINB12 Is a Slow-Binding Inhibitor of Granzyme A and Hepsin.
  Jason Z. Niehaus, Mark T. Miedel, Misty Good, Allyson N. Wyatt, Stephen C. Pak, Gary A. Silverman, Cliff J. Luke> ;Biochemistry. 2015 Nov 5
• 8 citations
  Deficient and Null Variants of SERPINA1 Are Proteotoxic in a Caenorhabditis elegans Model of α1-Antitrypsin Deficiency.
  Erin E. Cummings, Linda P. O’Reilly, Dale E. King, Richard M. Silverman, Mark T. Miedel, Cliff J. Luke, David H. Perlmutter, Gary A. Silverman, Stephen C. Pak> ;Plos One. 2015 Oct 29
• 16 citations
  Human SERPINB12 Is an Abundant Intracellular Serpin Expressed in Most Surface and Glandular Epithelia
  Jason Z. Niehaus, Misty Good, Laura E. Jackson, John A. Ozolek, Gary A. Silverman, Cliff J. Luke> ;The Journal of Histochemistry and Cytochemistry. 2015 Jul 28
• 1 citations
  The Aggregation-Prone Intracellular Serpin SRP-2 Fails to Transit the ER in Caenorhabditis elegans
  Richard M. Silverman, Erin E. Cummings, Linda P. O’Reilly, Gary A. Silverman, Cliff J. Luke, David H. Perlmutter, Stephen C. Pak> ;Genetics. 2015 Jan 1
• 7 citations
  Worming our way to novel drug discovery with the Caenorhabditis elegans proteostasis network, stress response and insulin-signaling pathways
  Linda P. O’Reilly, Joshua A. Benson, Erin E. Cummings, David H. Perlmutter, Gary A. Silverman, Stephen C. Pak> ;Expert Opinion on Drug Discovery. 2014 Aug 20
• Expanding the C. elegans toolbox into a toolshed.
  Arjumand Ghazi, Judith L. Yanowitz, Gary A. Silverman> ;Methods. 2014 Aug 1
• 4 citations
  Isolation of serpin-interacting proteins in C. elegans using protein affinity purification.
  Mark T. Miedel, Xuemei Zeng, Nathan A. Yates, Gary A. Silverman, Cliff J. Luke> ;Methods. 2014 Aug 1
• 20 citations
  A C. elegans model of human α1-antitrypsin deficiency links components of the RNAi pathway to misfolded protein turnover
  Olivia S. Long, Joshua A. Benson, Joon Hyeok Kwak, Cliff J. Luke, Sager J. Gosai, Linda P. O’Reilly, Yan Wang, Jie Li, Anne C. Vetica, Mark T. Miedel, Donna B. Stolz, ...> ;Human Molecular Genetics. 2014 May 16
• 27 citations
  A genome-wide RNAi screen identifies potential drug targets in a C. elegans model of α1-antitrypsin deficiency
  Linda P. O’Reilly, Olivia S. Long, Murat Can Cobanoglu, Joshua A. Benson, Cliff J. Luke, Mark T. Miedel, Pamela Hale, David H. Perlmutter, Ivet Bahar, Gary A. Silverma...> ;Human Molecular Genetics. 2014 May 16
• 154 citations
  C. elegans in high-throughput drug discovery.
  Linda P. O’Reilly, Cliff J. Luke, David H. Perlmutter, Gary A. Silverman, Stephen C. Pak> ;Advanced Drug Delivery Reviews. 2014 Apr 20
• 2 citations
  α1-Antitrypsin deficiency and the hepatocytes – An elegans solution to drug discovery
  Linda P. O’Reilly, David H. Perlmutter, Gary A. Silverman, Stephen C. Pak> ;The International Journal of Biochemistry & Cell Biology. 2014 Feb 1
• 29 citations
  Fluphenazine Reduces Proteotoxicity in C. elegans and Mammalian Models of Alpha-1-Antitrypsin Deficiency
  Jie Li, Stephen C. Pak, Linda P. O’Reilly, Joshua A. Benson, Yan Wang, Tunda Hidvegi, Pamela Hale, Christine S. Dippold, Michael Ewing, Gary A. Silverman, David H. Per...> ;Plos One. 2014 Jan 31
• 158 citations
  Update of the human and mouse SERPIN gene superfamily.
  Claire Heit, Brian C. Jackson, Monica S. McAndrews, Mathew W. Wright, David C. Thompson, Gary A. Silverman, Daniel W. Nebert, Vasilis Vasiliou> ;Human Genomics. 2013 Oct 30
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