GayMiriamCrooksMD

PubMed

• Generation of antigen-specific mature T cells from RAG1RAG2B2Mstem cells by engineering their microenvironment.
  Chang, P., Yuan, X., Zampieri, A., Towns, C., Yoo, S., Engstrom, C., Robles, C., Zhu, Y., Lopez, S., Montel-Hagen, A., Tsai, S., Seet, C., Crooks, G.> ;Nature Biomedical Engineering. 2023 Dec 7
• 6 citations
  IRIS: Discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing.
  Yang Pan, John W Phillips, Beatrice D Zhang, Miyako Noguchi, Eric Kutschera, Jami McLaughlin, Pavlo A Nesterenko, Zhiyuan Mao, Nathanael J Bangayan, Robert Wang, Wendy...> ;Proceedings of the National Academy of Sciences of the United States of America. 2023 May 23
• 13 citations
  Human T cell generation is restored in CD3δ severe combined immunodeficiency through adenine base editing.
  Grace E McAuley, Gloria Yiu, Patrick C Chang, Gregory A Newby, Beatriz Campo-Fernandez, Sorel T Fitz-Gibbon, Xiaomeng Wu, Sung-Hae L Kang, Amber Garibay, Jeffrey Butle...> ;Cell. 2023 Mar 30
• 8 citations
  Purine nucleoside phosphorylase enables dual metabolic checkpoints that prevent T cell immunodeficiency and TLR7-associated autoimmunity.
  Evan R Abt, Khalid Rashid, Thuc M Le, Suwen Li, Hailey R Lee, Vincent Lok, Luyi Li, Amanda L Creech, Amanda N Labora, Hanna K Mandl, Alex K Lam, Arthur Cho, Valerie Re...> ;The Journal of Clinical Investigation. 2022 Aug 15
• 4 citations
  Physical and in silico immunopeptidomic profiling of a cancer antigen prostatic acid phosphatase reveals targets enabling TCR isolation.
  Zhiyuan Mao, Pavlo A Nesterenko, Jami McLaughlin, Weixian Deng, Giselle Burton Sojo, Donghui Cheng, Miyako Noguchi, William Chour, Diana C DeLucia, Kathryn A Finton, Y...> ;Proceedings of the National Academy of Sciences of the United States of America. 2022 Aug 2
• 51 citations
  3D-organoid culture supports differentiation of human CARiPSCs into highly functional CAR T cells.
  Zhiqiang Wang, Helen P McWilliams-Koeppen, Hernan Reza, Julie R Ostberg, Wuyang Chen, Xiuli Wang, Christian Huynh, Vibhuti Vyas, Wen-Chung Chang, Renate Starr, Jamie R...> ;Cell Stem Cell. 2022 Apr 7
• 4 citations
  High Interferon Signature Leads to Increased STAT1/3/5 Phosphorylation in PBMCs From SLE Patients by Single Cell Mass Cytometry.
  Gloria Yiu, Tue Kruse Rasmussen, Brandon L Tsai, Vivian K Diep, David J Haddon, Jennifer Tsoi, Gopika D Miller, Begoña Comin-Anduix, Bent Deleuran, Gay M Crooks, Paul ...> ;Frontiers in Immunology. 2022 Jan 1
• Special Issue on pluripotent stem cells and hematopoiesis
  Amélie Montel-Hagen> ;Experimental Hematology. 2019 Feb 12
• The T-ALL related gene BCL11B regulates the initial stages of human T cell differentiation.
  Ha, V. L.,Luong, A.,Li, F.,Casero, D.,Malvar, J.,Kim, Y. M.,Bhatia, R.,Crooks, G. M.,Parekh, C.> ;Leukemia. 2017 Feb 25
• Long non-coding RNA profiling of human lymphoid progenitor cells reveals transcriptional divergence of B cell and T cell lineages.
  Casero, D.,Sandoval, S.,Seet, C. S.,Scholes, J.,Zhu, Y.,Ha, V. L.,Luong, A.,Parekh, C.,Crooks, G. M.> ;Nat. Immunol.. 2015 Oct 27
• 21 citations
  Lysophosphatidic acid mediates fibrosis in injured joints by regulating collagen type I biosynthesis
  Ling Wu, Frank A. Petrigliano, Kai Ba, Siyoung Lee, Jacob Bogdanov, David R. McAllister, John S. Adams, Ann K. Rosenthal, B. Van Handel, G.M. Crooks, Yunfeng Lin, Deni...> ;Osteoarthritis and Cartilage. 2015 Feb 1
• GPI-80 Defines Self-Renewal Ability in Hematopoietic Stem Cells during Human Development.
  Prashad, S. L.,Calvanese, V.,Yao, C. Y.,Kaiser, J.,Wang, Y.,Sasidharan, R.,Crooks, G.,Magnusson, M.,Mikkola, H. K.> ;Cell Stem Cell. 2014 Dec 04
• Perivascular Support of Human Hematopoietic stem/progenitor Cells
  Gay M Crooks, Chintan Parekh> ;Blood.
• Integrin alpha4 Blockade Sensitizes Drug Resistant Pre-B Acute Lymphoblastic Leukemia to Chemotherapy
  Carlton Scharman, Jacob Andrade, Hiroyuki Shimada, Mignon Loh, Gay M Crooks> ;Blood.
• Novel pathways to erythropoiesis induced by dimerization of intracellular C-mpl in human hematopoietic progenitors.
  Parekh, C., Sahaghian, A., Kim, W., Scholes, J., Ge, S., Zhu, Y., Asgharzadeh, S., Hollis, R., Kohn, D., Ji, L., Malvar, J., Wang, X., Crooks, G.> ;Stem Cells. 2012 Apr
• 1 citations
  Lineage assays: which pathway to take?
  GM Crooks> ;Blood. 2011 Mar 3
• VEGF-Mediated Cross-Talk Within the Neonatal Murine Thymus
  Gay Crooks, MD> ;Blood.
• Bone marrow fails to differentiate into liver epithelium during murine development and regeneration.
  Rountree, C.B., Wang, X., Ge, S., Barsky, L., Zhu, J., Gonzales, I., Crooks, G.M.> ;Hepatology. 2007 May
• 39 citations
  Stable gene transfer to human CD34(+) hematopoietic cells using the Sleeping Beauty transposon.
  Hollis, R. P., Nightingale, S. J., Wang, X., Pepper, K. A., Yu, X., Barsky, L., Crooks, G. M., Kohn, D. B.> ;Experimental hematology. 2006 Sep 20
• T cell depleted haploidentical bone marrow transplantation for the treatment of children with severe combined immunodeficiency.
  Smogorzewska, E. M., Brooks, J., Annett, G., Kapoor, N., Crooks, G. M., Kohn, D. B., Parkman, R., Weinberg, K. I.> ;Arch Immunol Ther Exp (Warsz). 2000
• Critical factors influencing stable transduction of human CD34(+) cells with HIV-1-derived lentiviral vectors.
  Haas, D. L., Case, S. S., Crooks, G. M., Kohn, D. B.> ;Mol Ther. 2000 Jul
• IL-3 increases production of B lymphoid progenitors from human CD34+CD38- cells.
  Crooks, G. M., Hao, Q. L., Petersen, D., Barsky, L. W., Bockstoce, D.> ;J Immunol. 2000 Sep 1
• Identification of a novel, human multilymphoid progenitor in cord blood.
  Hao, Q. L., Zhu, J., Price, M. A., Payne, K. J., Barsky, L. W., Crooks, G. M.> ;Blood. 2001 Jun 15
• Detection of leukemic cells in the CD34(+)CD38(-) bone marrow progenitor population in children with acute lymphoblastic leukemia.
  George, A. A., Franklin, J., Kerkof, K., Shah, A. J., Price, M., Tsark, E., Bockstoce, D., Yao, D., Hart, N., Carcich, S., Parkman, R., Crooks, G. M., Weinberg, K.> ;Blood. 2001 Jun 15
• Cutting edge: predominant expression of a novel Ikaros isoform in normal human hemopoiesis.
  Payne, K. J., Nicolas, J. H., Zhu, J. Y., Barsky, L. W., Crooks, G. M.> ;J Immunol. 2001 Aug 15
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Journal Articles

• IND-Enabling Studies for a Clinical Trial to Genetically Program a Persistent Cancer-Targeted Immune System  
  Kenneth Cornetta, Antoni Ribas, Gay M Crooks, Donald B Kohn, Clinical Cancer Research