GeorgeJAtieeMD

PubMed

• Population pharmacokinetic rationale for intravenous contezolid acefosamil followed by oral contezolid dosage regimens.
  Jürgen B Bulitta, Edward Fang, Martin E Stryjewski, Wen Wang, George J Atiee, Jeffrey G Stark, Barry Hafkin> ;Antimicrobial Agents and Chemotherapy. 2024 Apr 3
• A phase I, first-in-human study to evaluate the safety and tolerability, pharmacokinetics, and pharmacodynamics of MRG-001 in healthy subjects.
  Ali R Ahmadi, George Atiee, Bart Chapman, Laurie Reynolds, John Sun, Andrew M Cameron, Russell N Wesson, James F Burdick, Zhaoli Sun> ;Cell Reports. Medicine. 2023 Sep 19
• A Phase 1 pharmacokinetic study of a single-dose bioadhesive clindamycin 2% gel for bacterial vaginosis.
  Christine K Mauck, George J Atiee, Jennifer McCulloh, Laurie Reynolds, Nadene Zack, David R Friend> ;The Journal of Antimicrobial Chemotherapy. 2022 Dec 23
• 23 citations
  Improved Speech Intelligibility in Subjects With Stable Sensorineural Hearing Loss Following Intratympanic Dosing of FX-322 in a Phase 1b Study.
  Will Mclean, Ashley S. Hinton, Jenna T.J. Herby, Alec N. Salt, Jared J. Hartsock, Sam Wilson, David L. Lucchino, Thomas Lenarz, Athanasia Warnecke, Nils Prenzler, H Sc...> ;Otology & Neurotology. 2021 Feb 22
• 7 citations
  First-in-Human Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of an Oral Formulation of DS-1040, an Inhibitor of the Activated Form of Thrombin-Act...
  Jin Zhou, Tharin Limsakun, Ophelia Yin, Vance Warren, Cynthia Zamora, George Atiee, Jarema Kochan, Joseph Pav, Fumiaki Kobayashi, Vijay Vashi, Victor Dishy> ;Journal of Clinical Pharmacology. 2019 Dec 1
• 6 citations
  Comparing the Pharmacokinetics of 2 Novel Intravenous Tramadol Dosing Regimens to Oral Tramadol: A Randomized 3-Arm Crossover Study.
  Lucy Lu, Michael Ryan, Mark Harnett, George Atiee, Scott A Reines> ;Clinical Pharmacology in Drug Development. 2020 May 1
• 29 citations
  Clinical Pharmacokinetics and Drug-Drug Interaction Potential for Coadministered SCY-078, an Oral Fungicidal Glucan Synthase Inhibitor, and Tacrolimus.
  Stephen A. Wring, Gail Murphy, George Atiee, Christy Corr, Michele Hyman, Michael S. Willett, David Angulo> ;Clinical Pharmacology in Drug Development. 2019 Jan 1
• 2 citations
  Pharmacokinetics, Safety, and Tolerability of Single Oral Doses of a Novel Oxytocin Receptor Antagonist-Cligosiban-in Development for Premature Ejaculation: Three Rand...
  Ian H Osterloh, Gary J Muirhead, Stefan Sultana, Steven Whaley, Frans van den Berg, George Atiee> ;The Journal of Sexual Medicine. 2018 Nov 1
• 26 citations
  Lack of Impact by SCY-078, a First-in-Class Oral Fungicidal Glucan Synthase Inhibitor, on the Pharmacokinetics of Rosiglitazone, a Substrate for CYP450 2C8, Supports t...
  Stephen A. Wring, Gail Murphy, George Atiee, Christy Corr, Michele Hyman, Michael S. Willett, David Angulo> ;Journal of Clinical Pharmacology. 2018 Oct 1
• 11 citations
  Coadministration of probenecid and cimetidine with mirogabalin in healthy subjects: A phase 1, randomized, open-label, drug-drug interaction study.
  Masaya Tachibana, Naotoshi Yamamura, George Atiee, Ching Hsu, Vance Warren, Ling He, Victor Dishy, Hamim Zahir> ;British Journal of Clinical Pharmacology. 2018 Oct 1
• 15 citations
  An Open-Label Crossover Study of the Pharmacokinetics of the 60-mg Edoxaban Tablet Crushed and Administered Either by a Nasogastric Tube or in Apple Puree in Healthy A...
  Kenneth Duchin, Anil Duggal, George J. Atiee, Motonori Kidokoro, Tadanobu Takatani, N. Shipitofsky, Ling He, George Zhang, Tarundeep Kakkar> ;Clinical Pharmacokinetics. 2018 Feb 1
• 78 citations
  A Prospective Multicenter Evaluation of the Accuracy of a Novel Implanted Continuous Glucose Sensor: PRECISE II.
  Mark P. Christiansen, Leslie J. Klaff, Ronald L. Brazg, Anna R Chang, Carol J. Levy, David K. Lam, Douglas S Denham, George Atiee, Bruce W. Bode, Steven J Walters, Lyn...> ;Diabetes Technology & Therapeutics. 2018 Jan 30
• 4 citations
  A Phase 1 Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Oral Doses of DS-3801b, a Motilin Receptor Agonist, in Healthy Sub...
  Justin Dennie, George Atiee, Vance Warren, Ben Tao, Kiyoshi Morimoto, Giorgio Senaldi> ;Journal of Clinical Pharmacology. 2017 Sep 1
• A First-in-Human Study of DS-1040, an Inhibitor of the Activated Form of Thrombin-Activatable Fibrinolysis Inhibitor, in Healthy Subjects
  George Atiee, MD> ;Journal of Thrombosis and Haemostasis. 2017 Feb 18
• 165 citations
  First-in-human assessment of PRX002, an anti–α-synuclein monoclonal antibody, in healthy volunteers
  Dale Schenk, Martin Koller, Daniel K. Ness, Sue G. Griffith, Michael Grundman, Wagner Zago, Jay Soto, George Atiee, Susanne Ostrowitzki, Gene G. Kinney> ;Movement Disorders. 2017 Feb 1
• 3 citations
  Pleocytosis in cerebrospinal fluid following multiple lumbar punctures in healthy volunteers.
  George Atiee, John J. Sramek, Joseph Palasota, Sarah Andrews, Michael F. Murphy, Neal R. Cutler> ;Journal of the Neurological Sciences. 2016 Jan 15
• 14 citations
  Efficacy and Safety of AVP-21D9, an Anthrax Monoclonal Antibody, in Animal Models and Humans
  Nina V. Malkevich, Robert J. Hopkins, Edward Bernton, Gabriel T. Meister, Eric M. Vela, George Atiee, Virginia Johnson, Gary S. Nabors, Ronald T. Aimes, Boris Ionin, M...> ;Antimicrobial Agents and Chemotherapy. 2014 Jul 1
• 50 citations
  Gut Hormone Pharmacology of a Novel GPR119 Agonist (GSK1292263), Metformin, and Sitagliptin in Type 2 Diabetes Mellitus: Results from Two Randomized Studies
  Derek J. Nunez, Mark A. Bush, David A. Collins, Susan L. McMullen, Dawn S. Gillmor, Glen Apseloff, George Atiee, Leonor Corsino, Paul L. Feldman, Linda Morrow> ;Plos One. 2014 Apr 3
• 27 citations
  Safety of ragweed sublingual allergy immunotherapy tablets in adults with allergic rhinoconjunctivitis.
  Anjuli Nayak, George J. Atiee, Ea Dige, Jennifer Maloney, Hendrik Nolte> ;Allergy and Asthma Proceedings. 2012 Sep 1
• 15 citations
  Absence of pharmacokinetic interaction between intravenous peramivir and oral oseltamivir or rimantadine in humans.
  George Atiee, Kenneth C. Lasseter, Sharon A. Baughman, Amy McCullough, Phil Collis, Alan S. Hollister, Jaime E. Hernandez> ;Journal of Clinical Pharmacology. 2012 Sep 1
• 29 citations
  Pharmacokinetics and Safety of FV-100, a Novel Oral Anti-Herpes Zoster Nucleoside Analogue, Administered in Single and Multiple Doses to Healthy Young Adult and Elderl...
  Helen Pentikis, Mark Matson, George Atiee, Brian Boehlecke, Jeff T. Hutchins, Joseph M. Patti, Geoffrey W. Henson, Amy Morris> ;Antimicrobial Agents and Chemotherapy. 2011 Jun 1
• 2 citations
  Single Therapeutic and Supratherapeutic Doses of Laropiprant, a Selective Prostaglandin D2 Receptor 1 Antagonist, Do Not Prolong the QTcF Interval in Healthy Volunteers
  Wen-Lin Luo, Tami Crumley, David L. Ebel, George Atiee, Jane Royalty, Amy O. Johnson-Levonas, John A. Wagner, Eseng Lai> ;Journal of Clinical Pharmacology. 2010 Nov 1
• 14 citations
  Effects of Aspirin When Added to the Prostaglandin D2 Receptor Antagonist Laropiprant on Niacin‐Induced Flushing Symptoms
  Victor Dishy, Fang Liu, David L. Ebel, George Atiee, Jane Royalty, Sandra Reilley, John F. Paolini, John A. Wagner, Eseng Lai> ;Journal of Clinical Pharmacology. 2009 Apr 1
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