GeorgeCBobustucMD

Neurology • Austin, TX

Neurooncology

Physician

Join to view full profile

Dr. Bobustuc is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

Connect with other colleagues in the same hospital or clinic
Search all U.S. specialist profiles and refer a patient
Read the latest clinical news and earn CME/CEU credits

See Dr. Bobustuc's full profile

Already have an account?

Office
2600 E Martin Luther King Jr Blvd
Austin, TX 78702
Phone+1 512-505-5500
Is this information wrong?

Education & Training

University of Texas M D Anderson Cancer CenterFellowship, Neuro-Oncology, 1999 - 2001
University of Texas Health Science Center at HoustonResidency, Neurology, 1998 - 1999
University of Texas Southwestern Medical CenterResidency, Neurology, 1996 - 1998
University of Texas Health Science Center at HoustonInternship, Transitional Year, 1995 - 1996
Carol Davila University of Medicine and PharmacyClass of 1991

Certifications & Licensure

IL State Medical License 2002 - 2026
TX State Medical License 1999 - 2026
FL State Medical License 2004 - 2025
CA State Medical License 2020 - 2024
WI State Medical License 2012 - 2023
OK State Medical License 1999 - 2003
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013

Clinical Trials

Disulfiram and Copper Gluconate With Temozolomide in Unmethylated Glioblastoma Multiforme Start of enrollment: 2018 Mar 28
Terminated
Phase 2

Publications & Presentations

PubMed

Dark Blood Contrast-Enhanced Brain MRI Using Echo-uTRESS.
Robert R Edelman, Nondas Leloudas, William J Ankenbrandt, Matthew T Walker, George C Bobustuc, Julian E Bailes, Aaron A Pruitt, Ioannis Koktzoglou> ;Journal of Magnetic Resonance Imaging. 2023 Nov 10
1 citations
Improved Brain Tumor Conspicuity at 3 T Using Dark Blood, Fat-Suppressed, Dixon Unbalanced T1 Relaxation-Enhanced Steady-State MRI.
Robert R Edelman, Matthew Walker, William J Ankenbrandt, Nondas Leloudas, Jianing Pang, Julian Bailes, George Bobustuc, Ioannis Koktzoglou> ;Investigative Radiology. 2023 Sep 1
33 citations
Epidemiology of male breast cancer.
Santhi D. Konduri, Maharaj Singh, George C. Bobustuc, Richard A. Rovin, Amin B. Kassam> ;Breast. 2020 Aug 22
4 citations
Racial Disparity Among Women Diagnosed With Invasive Breast Cancer in a Large Integrated Health System.
Maharaj Singh, Santhi D. Konduri, George C. Bobustuc, Amin B Kassam, Richard A. Rovin> ;Journal of Patient-Centered Research and Reviews. 2018 Jul 30
14 citations
MGMT inhibition in ER positive breast cancer leads to CDC2, TOP2A, AURKB, CDC20, KIF20A, Cyclin A2, Cyclin B2, Cyclin D1, ERα and Survivin inhibition and enhances resp...
George C. Bobustuc, Amin B. Kassam, Richard A. Rovin, Sheila Jeudy, Joshua Smith, Beth Isley, Maharaj Singh, Ameya Paranjpe, Kalkunte S. Srivenugopal, Santhi D. Konduri> ;Oncotarget. 2018 Jul 3
13 citations
New insights into estrogenic regulation of O 6 -methylguanine DNA-methyltransferase (MGMT) in human breast cancer cells: Co-degradation of ER-α and MGMT proteins by fu...
Ameya Paranjpe, Nathan I. Bailey, Santhi D. Konduri, George C. Bobustuc, Francis Ali-Osman, Mohd Aslam Yusuf, Surendra R. Punganuru, Hanumantha Rao Madala, Debasish Ba...> ;Journal of Biomedical Research. 2016 Sep 6
10 citations
MGMT inhibition suppresses survivin expression in pancreatic cancer.
George C. Bobustuc, Anand Patel, Michael A. Thompson, Kalkunte S. Srivenugopal, Jacob Frick, James L. Weese, Santhi D. Konduri> ;Pancreas. 2015 May 1
97 citations
Disulfiram is a direct and potent inhibitor of human O6-methylguanine-DNA methyltransferase (MGMT) in brain tumor cells and mouse brain and markedly increases the alky...
Ameya Paranjpe, Ruiwen Zhang, Francis Ali-Osman, George C. Bobustuc, Kalkunte S. Srivenugopal> ;Carcinogenesis. 2014 Mar 1
14 citations
Recurrent inflammatory pseudotumor of the jaw with perineural intracranial invasion demonstrating sustained response to Rituximab.
Bryan A. Garcia, Sarah Tinsley, Thomas Schellenberger, George C. Bobustuc> ;Medical Oncology. 2012 Dec 1
9 citations
MGMT inhibition restores ERα functional sensitivity to antiestrogen therapy.
George C. Bobustuc, Joshua Smith, Sreeram Maddipatla, Sheila Jeudy, Arati Limaye, Beth Isley, Maria-Lourdes M Caparas, Susan M Constantino, Nikita Shah, Cheryl H. Bake...> ;Molecular Medicine. 2012 Sep 7
20 citations
Combination of 6-thioguanine, capecitabine, and celecoxib with temozolomide or lomustine for recurrent high-grade glioma
Tobias Walbert, Mark R. Gilbert, Morris D. Groves, Vinay K. Puduvalli, W. K. Alfred Yung, Charles A. Conrad, George C. Bobustuc, Howard Colman, Sigmund Hsu, B. Nebiyou...> ;Journal of Neuro-Oncology. 2011 Apr 1
113 citations
Levetiracetam enhances p53-mediated MGMT inhibition and sensitizes glioblastoma cells to temozolomide
George C. Bobustuc, Cheryl H. Baker, Arati Limaye, Wayne D. Jenkins, Gary Pearl, Nicholas G. Avgeropoulos, Santhi D. Konduri> ;Neuro-Oncology. 2010 Sep 1
6 citations
Gene transfer of COX-1 improves lumen size and blood flow in carotid bypass grafts
Harald C. Eichstaedt, Qi Liu, Zhi Qiang Chen, George C. Bobustuc, Toya Terry, James T. Willerson, P. Zoldhelyi> ;The Journal of Surgical Research. 2010 Jun 1
65 citations
Headache in Cerebral Venous Thrombosis: incidence, pattern and location in 200 consecutive patients.
Mohammad Wasay, Suleman Kojan, Alper I. Dai, George Bobustuc, Zubair Sheikh> ;The Journal of Headache and Pain. 2010 Jan 29
25 citations
Blockade of MGMT expression by O6 benzyl guanine leads to inhibition of pancreatic cancer growth and induction of apoptosis.
Santhi D. Konduri, Jonathan Ticku, George C. Bobustuc, Robert M. Sutphin, Jimmie Colon, Beth Isley, Kishor K. Bhakat, Srivenugopal S. Kalkunte, Cheryl H. Baker> ;Clinical Cancer Research. 2009 Oct 1
133 citations
Cerebral venous thrombosis: analysis of a multicenter cohort from the United States.
Mohammad Wasay, Rohit Bakshi, George Bobustuc, Suleman Kojan, Zubair Sheikh, Alper I. Dai, Zahid Cheema> ;Journal of Stroke and Cerebrovascular Diseases. 2008 Mar 1
6 citations
Local Gene Transduction of Cyclooxygenase-1 Increases Blood Flow in Injured Atherosclerotic Rabbit Arteries
Qi Liu, Zhiqiang Chen, George C. Bobustuc, Janice McNatt, Harry Segall, Su Pan, James T. Willerson, Pierre Zoldhelyi> ;Circulation. 2005 Apr 12
161 citations
Brain metastasis from prostate carcinoma: The M. D. Anderson Cancer Center experience.
Ivo W. Tremont-Lukats, George C. Bobustuc, George K. Lagos, Konstantinos Lolas, Athanassios P. Kyritsis, Vinay K. Puduvalli> ;Cancer. 2003 Jul 15
9 citations
Diffusion-Weighted Magnetic Resonance Imaging in Superior Sagittal Sinus Thrombosis
Mohammad Wasay, Rohit Bakshi, George Bobustuc, Neeraj Dubey, Zahid Cheema, Alper I. Dai> ;Journal of Neuroimaging. 2002 Jul 1
112 citations
Nonrandomized Comparison of Local Urokinase Thrombolysis Versus Systemic Heparin Anticoagulation for Superior Sagittal Sinus Thrombosis
Mohammad Wasay, Rohit Bakshi, Suleman Kojan, George Bobustuc, Neeraj Dubey, D. H. Unwin> ;Stroke. 2001 Oct 1
10 citations
Superior sagittal sinus thrombosis due to lithium: local urokinase thrombolysis treatment.
M Wasay, Rohit Bakshi, Suleman Kojan, George Bobustuc, Neeraj Dubey> ;Neurology. 2000 Jan 25
Join now to see all

Hospital Affiliations

Evanston HospitalEvanston, Illinois

GeorgeCBobustucMD

Dr. Bobustuc is on Doximity

Education & Training

Certifications & Licensure

Awards, Honors, & Recognition

Clinical Trials

Publications & Presentations

Hospital Affiliations

Viewing the full profile is available to verified healthcare professionals only.