GeorgeGillespieIIIDO

Family Medicine • Magee, MS

Emergency Medicine, Urgent Care

Emergency Physician/ EM Director Magee General Hospital/ Covington County Hospital

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Office
300 3rd Ave SE
Magee, MS 39111
Phone+1 601-849-5070
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Education & Training

North Mississippi Medical Center (Tupelo)Residency, Family Medicine, 2004 - 2007
Kansas City University of Medicine and Biosciences College of Osteopathic MedicineClass of 2004

Certifications & Licensure

MS State License 2006 - 2024
American Board of Family Medicine Family Medicine

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013

Publications & Presentations

PubMed

5 citations
Cancer Explant Models.
Christian T. Stackhouse, George Yancey Gillespie, Christopher D. Willey> ;Current Topics in Microbiology and Immunology. 2019 Mar 20
Myristoylated alanine-rich C-kinase substrate effector domain phosphorylation regulates the growth and radiation sensitization of glioblastoma.
Eustace, N. J.,Anderson, J. C.,Langford, C. P.,Trummell, H. Q.,Hicks, P. H.,Jarboe, J. S.,Mobley, J. A.,Hjelmeland, A. B.,Hackney, J. R.,Pedersen, R. T.,Cosby, K.,Gill...> ;Int. J. Oncol.. 2019 Apr 04
Safety and efficacy of oncolytic HSV-1 G207 inoculated into the cerebellum of mice.
Bernstock, J. D.,Vicario, N.,Li, R.,Nan, L.,Totsch, S. K.,Schlappi, C.,Gessler, F.,Han, X.,Parenti, R.,Beierle, E. A.,Whitley, R. J.,Aban, I.,Gillespie, G. Y.,Markert,...> ;Cancer Gene Ther.. 2019 Mar 29
17 citations
Stereotactic Placement of Intratumoral Catheters for Continuous Infusion Delivery of Herpes Simplex Virus -1 G207 in Pediatric Malignant Supratentorial Brain Tumors
Joshua D. Bernstock, Zachary Wright, Asim K. Bag, Florian Gessler, George Yancey Gillespie, James M. Markert, Gregory K. Friedman, James M. Johnston> ;World Neurosurgery. 2019 Feb 1
Characterization of iPSCs derived from low grade gliomas revealed early regional chromosomal amplifications during gliomagenesis.
Liu, Z.,Che, P.,Mercado, J. J.,Hackney, J. R.,Friedman, G. K.,Zhang, C.,You, Z.,Zhao, X.,Ding, Q.,Kim, K.,Li, H.,Liu, X.,Markert, J. M.,Nabors, B.,Gillespie, G. Y.,Zha...> ;J. Neurooncol.. 2018 Nov 22
51 citations
Enhanced Sensitivity of Patient-Derived Pediatric High-Grade Brain Tumor Xenografts to Oncolytic HSV-1 Virotherapy Correlates with Nectin-1 Expression
Gregory K. Friedman, Joshua D. Bernstock, Dongquan Chen, Li Nan, Blake P. Moore, Virginia M. Kelly, Samantha Youngblood, Catherine P. Langford, Xiaosi Han, Eric Ring, ...> ;Scientific Reports. 2018 Sep 17
Newly Characterized Murine Undifferentiated Sarcoma Models Sensitive to Virotherapy with Oncolytic HSV-1 M002.
Ring, E. K.,Li, R.,Moore, B. P.,Nan, L.,Kelly, V. M.,Han, X.,Beierle, E. A.,Markert, J. M.,Leavenworth, J. W.,Gillespie, G. Y.,Friedman, G. K.> ;Mol Ther Oncolytics. 2017 Oct 17
Chimeric HCMV/HSV-1 and Δγ134.5 oncolytic herpes simplex virus elicit immune mediated antigliomal effect and antitumor memory.
Ghonime, M. G.,Jackson, J.,Shah, A.,Roth, J.,Li, M.,Saunders, U.,Coleman, J.,Gillespie, G. Y.,Markert, J. M.,Cassady, K. A.> ;Transl Oncol. 2017 Dec 08
Intertumoral Heterogeneity Within Medulloblastoma Subgroups
G Yancey Gillespie, Reid C Thompson, Rajeev Vibhakar, William A Weiss, Linda M Liau, Samer K Elbabaa> ;Cell Press. 2017 Jun 14
24 citations
KLF6 depletion promotes NF-κB signaling in glioblastoma.
Anie P. Masilamani, Roberto Ferrarese, Eva Kling, Nanda K. Thudi, Hoon Kim, Denise M. Scholtens, Fangping Dai, Michael Hadler, T Unterkircher, L Platania, Astrid Weyer...> ;Oncogene. 2017 Feb 6
Integrated (Epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors
Lindsey M Hoffman, Amar Gajjar, A R Judkins, Nicholas K Foreman, G Yancey Gillespie> ;Cell Press. 2016 Dec 14
Pediatric medulloblastoma xenografts including molecular subgroup 3 and CD133+ and CD15+ cells are sensitive to killing by oncolytic herpes simplex viruses.
Friedman, G. K.,Moore, B. P.,Nan, L.,Kelly, V. M.,Etminan, T.,Langford, C. P.,Xu, H.,Han, X.,Markert, J. M.,Beierle, E. A.,Gillespie, G. Y.> ;Neuro-oncology. 2015 Jul 19
15 citations
Dynamics of Circulating γδ T Cell Activity in an Immunocompetent Mouse Model of High-Grade Glioma.
Benjamin H. Beck, Hyunggoon Kim, Rebecca L. O'Brien, Martin R. Jadus, G. Yancey Gillespie, Gretchen A. Cloud, Neil Hoa, Catherine P. Langford, Richard D. Lopez, Lualha...> ;Plos One. 2015 May 8
A Multi Targeting Conditionally Replicating Adenovirus Displays Enhanced Oncolysis while Maintaining Expression of Immunotherapeutic Agents.
Dobbins GC, Ugai H, Curiel DT, Gillespie GY> ;PLoS ONE. 2015-01-01
ROCK Inhibition Facilitates In Vitro Expansion of Glioblastoma Stem-Like Cells.
Tilson SG, Haley EM, Triantafillu UL, Dozier DA, Langford CP, Gillespie GY, Kim Y> ;PLoS ONE. 2015-01-01
Preclinical evaluation of engineered oncolytic herpes simplex virus for the treatment of pediatric solid tumors.
Megison ML, Gillory LA, Stewart JE, Nabers HC, Mroczek-Musulman E, Waters AM, Coleman JM, Kelly V, Markert JM, Gillespie GY, Friedman GK, Beierle EA> ;PLoS ONE. 2014-01-01
Combined efficacy of cediranib and quinacrine in glioma is enhanced by hypoxia and causally linked to autophagic vacuole accumulation.
Lobo MR, Wang X, Gillespie GY, Woltjer RL, Pike MM> ;PLoS ONE. 2014-01-01
Quinacrine synergistically enhances the antivascular and antitumor efficacy of cediranib in intracranial mouse glioma.
Lobo MR, Green SC, Schabel MC, Gillespie GY, Woltjer RL, Pike MM> ;Neuro-oncology. 2013-12-01
Engineered drug resistant γδ T cells kill glioblastoma cell lines during a chemotherapy challenge: a strategy for combining chemo- and immunotherapy.
Lamb LS, Bowersock J, Dasgupta A, Gillespie GY, Su Y, Johnson A, Spencer HT> ;PLoS ONE. 2013-01-01
Prognostic relevance of cytochrome C oxidase in primary glioblastoma multiforme.
Griguer CE, Cantor AB, Fathallah-Shaykh HM, Gillespie GY, Gordon AS, Markert JM, Radovanovic I, Clement-Schatlo V, Shannon CN, Oliva CR> ;PLoS ONE. 2013-01-01
CMV-independent lysis of glioblastoma by ex vivo expanded/activated Vδ1+ γδ T cells.
Knight A, Arnouk H, Britt W, Gillespie GY, Cloud GA, Harkins L, Su Y, Lowdell MW, Lamb LS> ;PLoS ONE. 2013-01-01
Preclinical evaluation of engineered oncolytic herpes simplex virus for the treatment of neuroblastoma.
Gillory LA, Megison ML, Stewart JE, Mroczek-Musulman E, Nabers HC, Waters AM, Kelly V, Coleman JM, Markert JM, Gillespie GY, Friedman GK, Beierle EA> ;PLoS ONE. 2013-01-01
Expression signature of IFN/STAT1 signaling genes predicts poor survival outcome in glioblastoma multiforme in a subtype-specific manner.
Duarte CW, Willey CD, Zhi D, Cui X, Harris JJ, Vaughan LK, Mehta T, McCubrey RO, Khodarev NN, Weichselbaum RR, Gillespie GY> ;PLoS ONE. 2012-01-01
Acquisition of chemoresistance in gliomas is associated with increased mitochondrial coupling and decreased ROS production.
Oliva CR, Moellering DR, Gillespie GY, Griguer CE> ;PLoS ONE. 2011-01-01
Downregulation of FIP200 induces apoptosis of glioblastoma cells and microvascular endothelial cells by enhancing Pyk2 activity.
Wang D, Olman MA, Stewart J, Tipps R, Huang P, Sanders PW, Toline E, Prayson RA, Lee J, Weil RJ, Palmer CA, Gillespie GY, Liu WM, Pieper RO, Guan J, Gladson CL> ;PLoS ONE. 2011-01-01
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Journal Articles

Original Article Stereotactic Placement of Intratumoral Catheters for Continuous Infusion Delivery of HSV-1 G207 in Pediatric Malignant Supratentorial Brain Tumors
Asim K Bag, G Yancey Gillespie, Gregory K Friedman, Zachary Wright, James M Markert, James M Johnston, ScienceDirect

Hospital Affiliations

Covington County HospitalCollins, Mississippi
Magee General HospitalMagee, Mississippi