GeorgeJaradMD

PubMed

• 8 citations
  Blocking CHOP-dependent TXNIP shuttling to mitochondria attenuates albuminuria and mitigates kidney injury in nephrotic syndrome.
  Sun-Ji Park, Yeawon Kim, Chuang Li, Junwoo Suh, Jothilingam Sivapackiam, Tassia M Goncalves, George Jarad, Guoyan Zhao, Fumihiko Urano, Vijay Sharma, Ying Maggie Chen> ;Proceedings of the National Academy of Sciences of the United States of America. 2022 Aug 30
• 4 citations
  Clinical trial recommendations for potential Alport syndrome therapies
  B. André Weinstock, David L. Feldman, Alessia Fornoni, Oliver Gross, Clifford E. Kashtan, Sharon Lagas, Rachel Lennon, Jeffrey H. Miner, Michelle N. Rheault, James F. ...> ;Kidney International. 2020 Jun 1
• 17 citations
  Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress
  Vasiliki Delitsikou, George Jarad, Renuga Devi Rajaram, Frédérique Ino, Joseph M. Rutkowski, Ci-Di Chen, Celio X.C. Santos, Philipp E. Scherer, Carmela R. Abraham, Aja...> ;FASEB Journal. 2020 Feb 1
• 32 citations
  Albumin contributes to kidney disease progression in Alport syndrome.
  George Jarad, Russell H. Knutsen, Robert P. Mecham, Jeffrey H. Miner> ;American Journal of Physiology. Renal Physiology. 2016 Jul 1
• 58 citations
  Albumin-associated free fatty acids induce macropinocytosis in podocytes
  Jun-Jae Chung, Tobias B. Huber, Markus Gödel, George Jarad, Björn Hartleben, Christopher Kwoh, Alexander Keil, Aleksey Karpitskiy, Jiancheng Hu, Christine J. Huh, Mari...> ;The Journal of Clinical Investigation. 2015 Jun 1
• 35 citations
  Forced expression of laminin β1 in podocytes prevents nephrotic syndrome in mice lacking laminin β2, a model for Pierson syndrome
  Jung Hee Suh, George Jarad, Rene G. VanDeVoorde, Jeffrey H. Miner> ;Proceedings of the National Academy of Sciences of the United States of America. 2011 Sep 13
• 27 citations
  Dystroglycan does not contribute significantly to kidney development or function, in health or after injury.
  George Jarad, Jeffrey W. Pippin, Stuart J. Shankland, Jordan A. Kreidberg, Jeffrey H. Miner> ;American Journal of Physiology. Renal Physiology. 2011 Mar 1
• 120 citations
  Activation of NFAT Signaling in Podocytes Causes Glomerulosclerosis
  Yinqiu Wang, George Jarad, Piyush Tripathi, Jeanette M. Cunningham, Daniel R. Martin, Helen Liapis, Jeffrey H. Miner, Feng Chen> ;Journal of the American Society of Nephrology. 2010 Oct 1
• 56 citations
  A new function for parietal epithelial cells: a second glomerular barrier
  Takamoto Ohse, Alice M. Chang, Jeffrey W. Pippin, George Jarad, Kelly L. Hudkins, Charles E. Alpers, Jeffrey H. Miner, Stuart J. Shankland> ;American Journal of Physiology. Renal Physiology. 2009 Sep 30
• 91 citations
  Update on the glomerular filtration barrier
  George Jarad, Jeffrey H. Miner> ;Current Opinion in Nephrology and Hypertension. 2009 May 1
• 13 citations
  Albuminuria, Wherefore Art Thou?
  George Jarad, Jeffrey H. Miner> ;Journal of the American Society of Nephrology. 2009 Mar 1
• 17 citations
  The Pax3-Cre transgene exhibits a rostrocaudal gradient of expression in the skeletal muscle lineage.
  George Jarad, Jeffrey H. Miner> ;Genesis. 2009 Jan 1
• 255 citations
  Podocyte-Specific Deletion of Dicer Alters Cytoskeletal Dynamics and Causes Glomerular Disease
  Scott J. Harvey, George Jarad, Jeanette M. Cunningham, Seth Goldberg, Bernhard Schermer, Brian D. Harfe, Michael T. McManus, Thomas Benzing, Jeffrey H. Miner> ;Journal of the American Society of Nephrology. 2008 Nov 1
• 100 citations
  Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction.
  Hiroshi Nishimune, Gregorio Valdez, George Jarad, Casey L. Moulson, Ulrich Müller, Jeffrey H. Miner, Joshua R. Sanes> ;The Journal of Cell Biology. 2008 Sep 22
• 139 citations
  β1 integrin expression by podocytes is required to maintain glomerular structural integrity
  Ambra Pozzi, George Jarad, Gilbert W. Moeckel, Sergio Coffa, Xi Zhang, Leslie Gewin, Vera Eremina, Billy G. Hudson, Dorin-Bogdan Borza, Raymond C. Harris, Lawrence B. ...> ;Developmental Biology. 2008 Apr 15
• 122 citations
  Disruption of Glomerular Basement Membrane Charge through Podocyte-Specific Mutation of Agrin Does Not Alter Glomerular Permselectivity
  Scott J. Harvey, George Jarad, Jeanette M. Cunningham, Angelique L.W.M.M. Rops, Johan van der Vlag, Jo H. M. Berden, Marcus J. Moeller, Lawrence B. Holzman, Robert W. ...> ;The American Journal of Pathology. 2007 Jul 1
• 157 citations
  Proteinuria precedes podocyte abnormalities inLamb2–/– mice, implicating the glomerular basement membrane as an albumin barrier
  George Jarad, Jeanette M. Cunningham, Andrey S. Shaw, Jeffrey H. Miner> ;The Journal of Clinical Investigation. 2006 Aug 1
• 34 citations
  β8 Integrin Binds Rho GDP Dissociation Inhibitor-1 and Activates Rac1 to Inhibit Mesangial Cell Myofibroblast Differentiation
  Sujata Lakhe-Reddy, Shenaz Khan, Martha Konieczkowski, George Jarad, Karen L. Wu, Louis F. Reichardt, Yoshimi Takai, Leslie A. Bruggeman, Bingcheng Wang, John R. Sedor...> ;The Journal of Biological Chemistry. 2006 Jul 14
• 118 citations
  Podocyte-Specific Deletion of Integrin-Linked Kinase Results in Severe Glomerular Basement Membrane Alterations and Progressive Glomerulosclerosis
  Chiraz El-Aouni, Nadja Herbach, Simone M. Blattner, Anna Henger, Maria Pia Rastaldi, George Jarad, Jeffrey H. Miner, Marcus J. Moeller, René St-Arnaud, Shoukat Dedhar,...> ;Journal of the American Society of Nephrology. 2006 May 1
• 62 citations
  Transgenic isolation of skeletal muscle and kidney defects in laminin beta2 mutant mice: implications for Pierson syndrome.
  Jeffrey H. Miner, Gloriosa Go, Jeanette M. Cunningham, Bruce L. Patton, George Jarad> ;Development. 2006 Mar 1
• 4 citations
  Renal phenotype is exacerbated in Os and lpr double mutant mice
  George Jarad, Sujata Lakhe-Reddy, Jeffrey A. Blatnik, Morgan Koepke, Shenaz Khan, M. Ashraf El-Meanawy, Andrew S. O’Connor, John R. Sedor, Jeffrey R. Schelling> ;Kidney International. 2004 Sep 1
• 136 citations
  The NHE1 Na+/H+ Exchanger Recruits Ezrin/Radixin/Moesin Proteins to Regulate Akt-dependent Cell Survival
  Karen L. Wu, Shenaz Khan, Sujata Lakhe-Reddy, George Jarad, Amitava Mukherjee, Carlos A. Obejero-Paz, Martha Konieczkowski, John R. Sedor, Jeffrey R. Schelling> ;The Journal of Biological Chemistry. 2004 Jun 18
• 6 citations
  Nucleic acid-based techniques for post-transcriptional regulation of molecular targets.
  George Jarad, Jeffrey S. Simske, John R. Sedor, Jeffrey R. Schelling> ;Current Opinion in Nephrology and Hypertension. 2003 Jul 1
• 59 citations
  Renal tubular epithelial cell apoptosis is associated with caspase cleavage of the NHE1 Na+/H+ exchanger.
  Karen L. Wu, Shenaz Khan, Sujata Lakhe-Reddy, Liming Wang, George Jarad, R. Tyler Miller, Martha Konieczkowski, Arthur M. Brown, John R. Sedor, Jeffrey R. Schelling> ;American Journal of Physiology. Renal Physiology. 2003 Apr 1
• 35 citations
  Fas Activation Induces Renal Tubular Epithelial Cell β8 Integrin Expression and Function in the Absence of Apoptosis
  George Jarad, Bingcheng Wang, Shenaz Khan, Jay DeVore, Hui Miao, Karen Wu, Stephen L. Nishimura, Barbara A. Wible, Martha Konieczkowski, John R. Sedor, Jeffrey R. Sche...> ;The Journal of Biological Chemistry. 2002 Dec 6
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