GeorgeJMurphyMD

PubMed

• 8 citations
  Inhibition of LSD1 by small molecule inhibitors stimulates fetal hemoglobin synthesis
  Cuong Le, Greggory Myers, Alawi Habara, Natee Jearawiriyapaisarn, George J. Murphy, David H.K. Chui, Martin H. Steinberg, James Douglas Engel, Shuaiying Cui> ;Blood. 2019 May 30
• 27 citations
  A phased SNP-based classification of sickle cell anemia HBB haplotypes.
  Elmutaz M. Shaikho, John J. Farrell, Abdulrahman Alsultan, Hatem O. Qutub, Amein K. Al-Ali, Maria Stella Figueiredo, David H.K. Chui, Lindsay A. Farrer, George J. Murp...> ;BMC Genomics. 2017 Aug 11
• 30 citations
  A Comprehensive, Ethnically Diverse Library of Sickle Cell Disease-Specific Induced Pluripotent Stem Cells.
  Seonmi Park, Andreia Gianotti-Sommer, F.J. Molina-Estevez, Kim Vanuytsel, Nick Skvir, Amy Leung, Sarah S. Rozelle, Elmutaz M. Shaikho, Isabelle R Weir, Zhihua Jiang, H...> ;Stem Cell Reports. 2017 Apr 11
• 14 citations
  A candidate transacting modulator of fetal hemoglobin gene expression in the Arab-Indian haplotype of sickle cell anemia.
  Vinod Vathipadiekal, John J. Farrell, Shuai Wang, Heather L. Edward, Heather Shappell, Abdullah M. Al-Rubaish, Fahad Al-Muhanna, Zaki A. Naserullah, Ahmed M. Al-Sulima...> ;American Journal of Hematology. 2016 Aug 22
• 12 citations
  Insulin-like growth factor 2 modulates murine hematopoietic stem cell maintenance through upregulation of p57
  Dolly D. Thomas, Andreia Gianotti Sommer, Alejandro B. Balazs, Isabel Beerman, George J. Murphy, Derrick J. Rossi, Gustavo Mostoslavsky> ;Experimental Hematology. 2016 May 1
• 6 citations
  Genome Editing of the CYP1A1 Locus in iPSCs as a Platform to Map AHR Expression throughout Human Development.
  Brenden W. Smith, Elizabeth A. Stanford, David H. Sherr, George J. Murphy> ;Stem Cells International. 2016 Apr 11
• 68 citations
  The role of the aryl hydrocarbon receptor in the development of cells with the molecular and functional characteristics of cancer stem-like cells
  Elizabeth A. Stanford, Zhongyan Wang, Olga Novikov, Francesca Mulas, Esther Landesman-Bollag, Stefano Monti, Brenden W. Smith, David C. Seldin, George J. Murphy, David...> ;BMC Biology. 2016 Mar 16
• 55 citations
  Emergence of a Stage-Dependent Human Liver Disease Signature with Directed Differentiation of Alpha-1 Antitrypsin-Deficient iPS Cells
  Andrew A. Wilson, Lei Ying, Marc Liesa, Charis Patricia Segeritz, Jason A. Mills, Steven S. Shen, Jyh-Chang Jean, Geordie C. Lonza, Derek C. Liberti, Alex H. Lang, Jea...> ;Stem Cell Reports. 2015 May 12
• 14 citations
  Stem cells, megakaryocytes, and platelets.
  Brenden W. Smith, George J. Murphy> ;Current Opinion in Hematology. 2014 Sep 1
• 89 citations
  ALS-Linked Mutations Enlarge TDP-43-Enriched Neuronal RNA Granules in the Dendritic Arbor
  Li Qun Liu-Yesucevitz, Amy Lin, Atsushi Ebata, Joon Y. Boon, Whitney Reid, Ya Fei Xu, Kendra Kobrin, George J. Murphy, Leonard Petrucelli, Benjamin Wolozin> ;The Journal of Neuroscience. 2014 Mar 19
• 4 citations
  Multisystemic Disease Modeling of Liver-Derived Protein Folding Disorders Using Induced Pluripotent Stem Cells (iPSCs).
  Amy Leung, George J. Murphy> ;Methods in Molecular Biology. 2014 Jan 1
• 34 citations
  Induced Pluripotent Stem Cell Modeling of Multisystemic, Hereditary Transthyretin Amyloidosis
  Amy Leung, Shirley K. Nah, Whitney Reid, Atsushi Ebata, Clarissa M. Koch, Stefano Monti, Joseph C. Genereux, R. Luke Wiseman, Benjamin Wolozin, Lawreen H. Connors, Joh...> ;Stem Cell Reports. 2013 Nov 19
• 101 citations
  The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation.
  Brenden W. Smith, Sarah S. Rozelle, Amy Leung, Jessalyn M. Ubellacker, Ashley J. Parks, Shirley K. Nah, Deborah L. French, Paul Gadue, Stefano Monti, David H.K. Chui, ...> ;Blood. 2013 Jul 18
• 41 citations
  Mouse ES and iPS cells can form similar definitive endoderm despite differences in imprinted genes.
  Constantina Christodoulou, Tyler A. Longmire, Steven S. Shen, Alice Bourdon, Cesar Sommer, Paul Gadue, Avrum Spira, Valerie Gouon-Evans, George J. Murphy, Gustavo Most...> ;The Journal of Clinical Investigation. 2011 Jun 1
• 307 citations
  Generation of Transgene‐Free Lung Disease‐Specific Human Induced Pluripotent Stem Cells Using a Single Excisable Lentiviral Stem Cell Cassette
  Aba Somers, Jyh-Chang Jean, Cesar Sommer, Amel Omari, Christopher C. Ford, Jason A. Mills, Lei Ying, Andreia Gianotti Sommer, Jenny M. Jean, Brenden W. Smith, Robert L...> ;Stem Cells. 2010 Oct 1
• 66 citations
  Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages
  Andrew A. Wilson, George J. Murphy, Hiroshi Hamakawa, Letty W. Kwok, Sreedevi Srinivasan, Avi-Hai Hovav, Richard C. Mulligan, Salomon Amar, Béla Suki, Darrell N. Kotton> ;The Journal of Clinical Investigation. 2010 Jan 4
• 199 citations
  Excision of Reprogramming Transgenes Improves the Differentiation Potential of iPS Cells Generated with a Single Excisable Vector
  Cesar Sommer, Andreia Gianotti Sommer, Tyler A. Longmire, Constantina Christodoulou, Dolly D. Thomas, Monica Gostissa, Frederick W. Alt, George J. Murphy, Darrell N. K...> ;Stem Cells. 2010 Jan 1
• 490 citations
  Induced Pluripotent Stem Cell Generation Using a Single Lentiviral Stem Cell Cassette
  Cesar Sommer, Matthias Stadtfeld, George J. Murphy, Konrad Hochedlinger, Darrell N. Kotton, Gustavo Mostoslavsky> ;Stem Cells. 2009 Mar 1
• 42 citations
  Exogenous control of mammalian gene expression via modulation of translational termination
  George J. Murphy, Gustavo Mostoslavsky, Darrell N. Kotton, Richard C. Mulligan> ;Nature Medicine. 2006 Aug 6
• 110 citations
  LPAM (α4β7 integrin) is an important homing integrin on alloreactive T cells in the development of intestinal graft-versus-host disease
  Aleksandra Petrovic, Onder Alpdogan, Lucy M. Willis, Jeffrey M. Eng, Andrew S. Greenberg, Barry J. Kappel, Chen Liu, George J. Murphy, Glenn Heller, Marcel R.M. van de...> ;Blood. 2004 Feb 15
• 4 citations
  Using Retroviruses to Express Genes in Primary Megakaryocyte Lineage Cells
  Meenakshi Gaur, George J. Murphy, Jonathan Frampton, Andrew D. Leavitt> ;Methods in Molecular Biology. 2004 Jan 1
• Manipulation of gene expression in megakaryocytes.
  Nikla R. Emambokus, George J. Murphy, Jonathan Frampton> ;Methods in Molecular Biology. 2004 Jan 1
• 12 citations
  Manipulation of mouse hematopoietic progenitors by specific retroviral infection.
  George J. Murphy, Berthold Göttgens, Alexandros Vegiopoulos, María José Sánchez, Andrew D. Leavitt, Stephen P. Watson, Anthony R. Green, Jonathan Frampton> ;The Journal of Biological Chemistry. 2003 Oct 31
• Tyrosine 36 plays a critical role in the interaction of the AB loop of tissue inhibitor of metalloproteinases-2 with matrix metalloproteinase-14.
  Williamson RA, Hutton M, Vogt G, Rapti M, Knäuper V, Carr MD, Murphy G> ;J. Biol. Chem.. 2001-08-31
• Specific collagenolysis by gelatinase A, MMP-2, is determined by the hemopexin domain and not the fibronectin-like domain.
  Patterson ML, Atkinson SJ, Knäuper V, Murphy G> ;FEBS Lett.. 2001-08-17
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