
George C Tsokos MD
Lupus & Related
Professor of Medicine, Beth Israel Deaconess Medical Center
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330 Brookline Ave # Cls-937Beth Israel Deaconess MedicalBoston, MA 02215
Phone+1 617-735-4161
Fax+1 617-735-4170
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Summary
- George Tsokos, MD is a renowned rheumatologist based in Boston, MA, with a subspecialty in Lupus and related diseases. His education includes a fellowship in Immunology and Rheumatology at the National Institutes of Health Clinical Center, followed by a residency in Internal Medicine at MedStar Health/Georgetown University Hospital. Currently, he serves as a Professor of Medicine at Harvard Medical School and Chief of Rheumatology and Clinical Immunology at Beth Israel Deaconess Medicine Center. Dr. Tsokos has extensive experience in systemic lupus erythematosus and has numerous publications in respected journals like Nature Immunology, Nature Communications, Science Translational Medicine, NEJM and the Journal of Clinical Investigation. His work has been funded continuously by NIH for more than 30 years. He is notably a Master of the American College of Physicians, the American College of Rheumatology and Fellow of the AAAS and has been recognized as a Super Doctor by SuperDoctors.com. He has received numerous national and international awards.
Education & Training
National Institutes of Health Clinical CenterFellowship, Allergy and Immunology, 1983 - 1984
MedStar Health Georgetown University/Georgetown HospitalResidency, Internal Medicine, 1981 - 1982
National Institutes of Health Clinical CenterFellowship, Rheumatology, 1979 - 1981
University of AthensClass of 1975
Certifications & Licensure
MA State Medical License 1980 - 2027
VA State Medical License 1983 - 2008
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Diagnostic Laboratory Immunology
American Board of Internal Medicine Rheumatology
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification Online Medical Record, Beth Israel Deaconess Medical Center, 2012, 2014
- Super Doctor SuperDoctors.com
- Fellow American College of Rheumatology
Publications & Presentations
PubMed
- Development and validation of a lectin-based assay for detection of IgG Fc glycosylation as a biomarker in lupus nephritis.Rohit Upadhyay, Juan Gao, Alexia M Michelle Orellana Enamorado, Scott E Wenderfer, George C Tsokos
Lupus Science & Medicine. 2026-07-02 - IgG Glycosylation-Dependent CLEC7A Signaling Drives Podocyte Dysfunction in Lupus Nephritis.Rohit Upadhyay, Alexia Orellana, George C Tsokos, Rhea Bhargava
Arthritis & Rheumatology. 2026-06-22 - 1 citationsADAM9 supports regulatory T cell stability through TGF-β-SMAD signaling and is reduced in systemic lupus erythematosus.Theodoros Vichos, Wei Li, Kohei Karino, Limor Rubin, Maria G Tsokos
Clinical Immunology. 2026-06-01
Journal Articles
- Regulatory T Cells in the Treatment of DiseaseGeorge Tsokos, MD, Nature
- Pyruvate Dehydrogenase Phosphatase Catalytic Subunit 2 Limits Th17 DifferentiationVasileios C Kyttaris, George C Tsokos, Proceedings of the National Academy of Sciences
- SLAMF1 Engagement Inhibits T Cell‐B Cell Interaction and Diminishes IL‐6 Production and Plasmablast Differentiation in Systemic Lupus ErythematosusGeorge C Tsokos, Vasileios C Kyttaris, Arthritis & Rheumatology
Press Mentions
ACR Open Rheumatology Editor Anticipates Broader Scope & Greater Impact for the Open-Access JournalFebruary 28th, 2025
Experts to Explain Why CAR-T Cell Therapy Is Promising but Not a Cure-AllNovember 8th, 2024
AMPEL BioSolutions' Breakthrough Predicts Drug Options to Slow End Stage Renal DiseaseMarch 1st, 2023
Grant Support
- Phosphatases in lupusBETH ISRAEL DEACONESS MEDICAL CENTER2025–2030
- Lupus nephritis: novel insights in the pathogenesis and treatmentBETH ISRAEL DEACONESS MEDICAL CENTER2024–2029
- Gene Transcription in SLEBETH ISRAEL DEACONESS MEDICAL CENTER2002–2028
- Expanded Double Negative T cells in SLE.BETH ISRAEL DEACONESS MEDICAL CENTER2010–2026
- Phosphatases In Human LupusNational Institute Of Allergy And Infectious Diseases2007–2012
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