GeraldLinetteMDPhD

PubMed

• Facts and hopes in immunotherapy strategies targeting antigens derived from KRAS mutations.
  Gerald P Linette, Adham S Bear, Beatriz M Carreno> ;Clinical Cancer Research. 2024 Jan 24
• 2 citations
  A genetically encoded protein tag for control and quantitative imaging of CAR T cell therapy.
  Iris K Lee, Nitika Sharma, Estela Noguera-Ortega, Maria Liousia, Miren L Baroja, Jean M Etersque, Jonathan Pham, Swarbhanu Sarkar, Beatriz M Carreno, Gerald P Linette,...> ;Molecular Therapy. 2023 Dec 6
• 5 citations
  Phase I Trial of Autologous RNA-electroporated cMET-directed CAR T Cells Administered Intravenously in Patients with Melanoma and Breast Carcinoma.
  Payal D Shah, Alexander C Huang, Xiaowei Xu, Robert Orlowski, Ravi K Amaravadi, Lynn M Schuchter, Paul Zhang, Julia Tchou, Tina Matlawski, Amanda Cervini, Joanne Shea,...> ;Cancer Research Communications. 2023 May 1
• 10 citations
  Expression of inducible factors reprograms CAR-T cells for enhanced function and safety.
  Anže Smole, Alexander Benton, Mathilde A Poussin, Monika A Eiva, Claudia Mezzanotte, Barbara Camisa, Beatrice Greco, Prannda Sharma, Nicholas G Minutolo, Falon Gray, A...> ;Cancer Cell. 2022 Dec 12
• 12 citations
  Anti-BCMA/CD19 CAR T Cells with Early Immunomodulatory Maintenance for Multiple Myeloma Responding to Initial or Later-Line Therapy.
  Alfred L Garfall, Adam D Cohen, Sandra P Susanibar-Adaniya, Wei-Ting Hwang, Dan T Vogl, Adam J Waxman, Simon F Lacey, Vanessa E Gonzalez, Joseph A Fraietta, Minnal Gup...> ;Blood Cancer Discovery. 2023 Mar 1
• A Phase I Study of Apolizumab, an Anti-HLA-DR ß-chain Monoclonal Antibody, in Patients With Solid Tumor Malignancies.
  Paula M Fracasso, Sherry A Goodner, Jonathan D Wildi, Michael J Naughton, Gerald P Linette, Ramaswamy Govindan, Benjamin R Tan, Kristie A Blum, Gary J Jones, Tillman E...> ;American Journal of Clinical Oncology. 2022 Jul 1
• 22 citations
  BAMM (BRAF Autophagy and MEK Inhibition in Melanoma): A Phase I/II Trial of Dabrafenib, Trametinib, and Hydroxychloroquine in Advanced BRAFV600-mutant Melanoma.
  Janice M Mehnert, Tara C Mitchell, Alexander C Huang, Tomas S Aleman, Benjamin J Kim, Lynn M Schuchter, Gerald P Linette, Giorgos C Karakousis, Sheryl Mitnick, Lydia G...> ;Clinical Cancer Research. 2022 Mar 15
• 4 citations
  On the Twentieth Anniversary of Dendritic Cell Vaccines - Riding the Next Wave.
  Gerald P Linette, Beatriz M Carreno> ;Cancer Research. 2022 Mar 15
• 21 citations
  Avelumab in patients with previously treated metastatic Merkel cell carcinoma (JAVELIN Merkel 200): updated overall survival data after >5 years of follow-up
  Sandra P. D'Angelo, Shailender Bhatia, A.S. Brohl, Omid Hamid, Janice M. Mehnert, Patrick Terheyden, Kent C. Shih, Isaac Brownell, Céleste Lebbé, Karl D. Lewis, Gerald...> ;ESMO Open. 2021 Oct 26
• 19 citations
  Novel phosphatidylserine-binding molecule enhances antitumor T-cell responses by targeting immunosuppressive exosomes in human tumor microenvironments.
  Maulasri Bhatta, Gautam N Shenoy, Jenni L Loyall, Brian D. Gray, Meghana V. Bapardekar, Alexis Conway, Hans Minderman, Raymond J. Kelleher, Beatriz M. Carreno, Gerald ...> ;Journal for Immunotherapy of Cancer. 2021 Oct 1
• 39 citations
  Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting.
  Adham S. Bear, Tatiana Blanchard, Joseph Cesare, Michael J. Ford, Lee P. Richman, Chong Xu, Miren L. Baroja, Sarah McCuaig, Christina Costeas, Khatuna Gabunia, John Sc...> ;Nature Communications. 2021 Jul 16
• 181 citations
  Adjuvant pembrolizumab versus placebo in resected stage III melanoma (EORTC 1325-MG/KEYNOTE-054): distant metastasis-free survival results from a double-blind, randomi...
  Alexander M.M. Eggermont, Christian U. Blank, Mario Mandalà, Georgina V. Long, Victoria Atkinson, Stéphane Dalle, Andrew Haydon, Andrey Meshcheryakov, Adnan Khattak, M...> ;The Lancet. Oncology. 2021 May 1
• 32 citations
  Adjuvant pembrolizumab versus placebo in resected stage III melanoma (EORTC 1325-MG/KEYNOTE-054): health-related quality-of-life results from a double-blind, randomise...
  Andrew Bottomley, Corneel Coens, Justyna Mierzynska, Christian U. Blank, Mario Mandalà, Georgina V. Long, Victoria Atkinson, Stéphane Dalle, Andrew Haydon, Andrey Mesh...> ;The Lancet. Oncology. 2021 May 1
• 4 citations
  Preclinical evaluation of cancer immune therapy using patient-derived tumor antigen-specific T cells in a novel xenograft platform.
  Gautam N Shenoy, Christopher J. Greene, Maulasri Bhatta, Miren L. Baroja, Jenni L Loyall, Sathy V. Balu-Iyer, Raymond J. Kelleher, Beatriz M. Carreno, Gerald P. Linett...> ;Clinical & Translational Immunology. 2021 Jan 1
• 113 citations
  Avelumab in patients with previously treated metastatic Merkel cell carcinoma: long-term data and biomarker analyses from the single-arm phase 2 JAVELIN Merkel 200 trial
  Sandra P. D'Angelo, Shailender Bhatia, Andrew S. Brohl, Omid Hamid, Janice M. Mehnert, Patrick Terheyden, Kent C. Shih, Isaac Brownell, Céleste Lebbé, Karl D. Lewis, G...> ;Journal for Immunotherapy of Cancer. 2020 May 1
• 33 citations
  Immunological ignorance is an enabling feature of the oligo-clonal T cell response to melanoma neoantigens.
  Gerald P. Linette, Michelle Becker-Hapak, Zachary L. Skidmore, Miren L. Baroja, Chong Xu, Jasreet Hundal, David H. Spencer, Weixuan Fu, Casey L. Cummins, Maya G. Robne...> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Nov 19
• 9 citations
  Primary Bone Tumors: Challenges and Opportunities for CAR-T Therapies.
  Ian W. Folkert, Samir Devalaraja, Gerald P. Linette, Kristy L. Weber, Malay Haldar> ;Journal of Bone and Mineral Research. 2019 Oct 1
• 53 citations
  Tumor-Infiltrating Lymphocytes in the Checkpoint Inhibitor Era
  Gerald P. Linette, Beatriz M. Carreno> ;Current Hematologic Malignancy Reports. 2019 Aug 1
• 403 citations
  A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma
  Alexander C. Huang, Robert J. Orlowski, Xiaowei Xu, Rosemarie Mick, Sangeeth M. George, Patrick Yan, Sasikanth Manne, Adam A. Kraya, Bradley Wubbenhorst, Liza Dorfman,...> ;Nature Medicine. 2019 Feb 25
• 19 citations
  Early objective response to avelumab treatment is associated with improved overall survival in patients with metastatic Merkel cell carcinoma
  Sandra P. D'Angelo, Matthias Hunger, Andrew S. Brohl, Paul Nghiem, Shailender Bhatia, Omid Hamid, Janice M. Mehnert, Patrick Terheyden, Kent C. Shih, Isaac Brownell, C...> ;Cancer Immunology, Immunotherapy. 2019 Feb 5
• 3 citations
  RNA-seq for identification of therapeutically targetable determinants of immune activation in human glioblastoma.
  Stephen J Bagley, Wei-Ting Hwang, Steven Brem, Gerald P. Linette, Donald M. O'Rourke, Arati Desai> ;Journal of Neuro-Oncology. 2019 Jan 1
• 171 citations
  CAR T-cell therapy for glioblastoma: recent clinical advances and future challenges.
  Stephen J Bagley, Arati Desai, Gerald P. Linette, Carl H. June, Donald M. O'Rourke> ;Neuro-Oncology. 2018 Oct 9
• 2 citations
  Health-related quality of life in patients with malignant melanoma by stage and treatment status.
  A.R. Rosenberg, Sara J. Weston, Teresa L. Deshields, Ryan C. Fields, Gerald P. Linette, Lynn A. Cornelius, Yevgeniy R. Semenov> ;Journal of the American Academy of Dermatology. 2021 Aug 1
• 170 citations
  Selumetinib in Combination With Dacarbazine in Patients With Metastatic Uveal Melanoma: A Phase III, Multicenter, Randomized Trial (SUMIT)
  Richard D. Carvajal, Sophie Piperno-Neumann, Ellen Kapiteijn, Paul B. Chapman, Stephen Frank, Anthony M. Joshua, Josep M. Piulats, Pascal Wolter, Veronique Cocquyt, Ba...> ;Journal of Clinical Oncology. 2018 Mar 12
• 28 citations
  Phase IIIb safety results from an expanded-access protocol of talimogene laherparepvec for patients with unresected, stage IIIB-IVM1c melanoma.
  Jason Chesney, Sanjay Awasthi, Brendan D. Curti, Laura F. Hutchins, Gerald P. Linette, Pierre L. Triozzi, Marcus C.B. Tan, Russell E. Brown, John Nemunaitis, Eric D. W...> ;Melanoma Research. 2018 Feb 1
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