GerardCrinerMD

Pulmonology • Philadelphia, PA

Critical Care Medicine, Pleural Disease

Professor of Medicine, Temple Univ

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Office
3401 N Broad St
Philadelphia, PA 19140
Phone+1 215-707-5864

Fax+1 215-707-6867
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Education & Training

Boston University Medical CenterFellowship, Pulmonary Disease and Critical Care Medicine, 1983 - 1986
Temple University HospitalResidency, Internal Medicine, 1979 - 1982
Lewis Katz School of Medicine at Temple UniversityClass of 1979

Certifications & Licensure

PA State Medical License 1980 - 2024
MD State Medical License 1986 - 1988
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Critical Care Medicine
American Board of Internal Medicine Pulmonary Disease

Awards, Honors, & Recognition

Philadelphia Magazine Castle Connolly, 2009-2014
America's Top Doctors Castle Connolly, 2009-2014
Super Doctor SuperDoctors.com
Top MD Consumers Checkbook
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Clinical Trials

Benefits of Lightweight Ambulatory Oxygen Systems for Individuals With Chronic Obstructive Pulmonary Disease Start of enrollment: 2005 Mar 01
Terminated
Not Applicable
Macrolide Azithromycin to Prevent Rapid Worsening of Symptoms Associated With Chronic Obstructive Pulmonary Disease Start of enrollment: 2006 Mar 01
Completed
Not Applicable
US 10 mL Biologic Lung Volume Reduction (BLVR) Phase 2 Emphysema Study Start of enrollment: 2007 Feb 01
Completed
Phase 2
US Biologic Lung Volume Reduction (BLVR) Phase 2 Emphysema Study Start of enrollment: 2007 Aug 01
Completed
Phase 2
Pennsylvania Idiopathic Pulmonary Fibrosis Research Registry Start of enrollment: 2007 Sep 01
Completed
Biologic Lung Volume Reduction (BLVR) Phase 2 Homogeneous Study Start of enrollment: 2008 Feb 01
Completed
Phase 2
Long-term Oxygen Treatment Trial Start of enrollment: 2009 Jan 01
Completed
Phase 3
Pennsylvania Study Of Chronic Obstructive Pulmonary Exacerbations Start of enrollment: 2004 Jun 01
Completed
Simvastatin Therapy for Moderate and Severe COPD Start of enrollment: 2010 Mar 01
Terminated
Phase 3
Symbicort in Airway Predominant Chronic Obstructive Pulmonary Disease (COPD) Start of enrollment: 2012 Apr 01
Completed
Phase 4
Lung Volume Reduction Coil Treatment in Patients With Emphysema (RENEW) Study Start of enrollment: 2012 Oct 01
Terminated
Not Applicable
Pulmonx Endobronchial Valves Used in Treatment of Emphysema (LIBERATE Study) Start of enrollment: 2013 Jul 01
Completed
Not Applicable
Prostaglandin Inhibition for Emphysema Start of enrollment: 2014 Jan 01
Completed
Phase 2
Benralizumab Efficacy in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With Exacerbation History Start of enrollment: 2014 Jun 13
Completed
Phase 3
The Frequency of Screening and SBT Technique Trial: The FAST Trial Start of enrollment: 2018 Jan 18
Recruiting
Not Applicable
Respiration Rate Monitoring in COPD Patients Start of enrollment: 2016 Dec 01
Completed
Not Applicable
RejuvenAir® System Trial for COPD With Chronic Bronchitis Start of enrollment: 2020 Jul 09
Recruiting
Not Applicable
Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent Exacerbations Start of enrollment: 2019 Aug 26
Recruiting
Phase 3
Study of CPI-006 as Immunotherapy for Hospitalized COVID-19 Patients Start of enrollment: 2020 Jul 01
Completed
Phase 1
Video Telehealth Pulmonary Rehabilitation to Reduce Hospital Readmission in Chronic Obstructive Pulmonary Disease Start of enrollment: 2022 Jun 28
Recruiting
Not Applicable
Roles: Contact
Tolerance and Acute Effects of a New HFNT Nasal Cannula Start of enrollment: 2022 May 25
Completed
Not Applicable
Roles: Principal Investigator, Contact
Autoantibody Reduction for Acute Exacerbations of Idiopathic Pulmonary Fibrosis Start of enrollment: 2018 Sep 04
Recruiting
Phase 2
Roles: Contact
DECAMP 1 PLUS: Prediction of Lung Cancer Using Noninvasive Biomarkers Start of enrollment: 2020 Aug 24
Recruiting
Roles: Contact
Extracorporeal CO2 Removal With the Hemolung RAS for Mechanical Ventilation Avoidance During Acute Exacerbation of COPD Start of enrollment: 2018 Feb 18
Terminated
Not Applicable
Roles: Contact, Principal Investigator
Functional Lung Imaging in Patients With Respiratory Compromise Undergoing Endobronchial Valve Placement Start of enrollment: 2022 Jul 05
Recruiting
Roles: Principal Investigator, Contact
Prospective Treatment Efficacy in IPF Using Genotype for Nac Selection (PRECISIONS) Trial Start of enrollment: 2020 Dec 17
Active, not recruiting
Phase 3
Roles: Contact
myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home Start of enrollment: 2022 Feb 02
Recruiting
Not Applicable
Roles: Contact
Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Single Lung Transplant (BOSTON-2) Start of enrollment: 2019 Mar 29
Active, not recruiting
Phase 3
Roles: Contact
Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Single Lung Transplant (BOSTON-1) Start of enrollment: 2019 Apr 02
Active, not recruiting
Phase 3
Roles: Contact
Trial of Therapeutic Hypothermia in Patients With ARDS Start of enrollment: 2021 Jun 29
Recruiting
Phase 2
Roles: Sub-Investigator
Clinical Effectiveness Of High Frequency Chest Wall Oscillation (HFCWO) In A Bronchiectasis Population Start of enrollment: 2020 Feb 18
Completed
Roles: Contact
GKT137831 in IPF Patients With Idiopathic Pulmonary Fibrosis Start of enrollment: 2020 Sep 07
Recruiting
Phase 2
Roles: Contact
Doxycycline for Emphysema in People Living With HIV (The DEPTH Trial) Start of enrollment: 2022 Aug 22
Recruiting
Phase 2
Roles: Contact
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Publications & Presentations

PubMed

The Effect of Chronic Altitude Exposure on COPD Outcomes in the SPIROMICS Cohort.
Rajat Suri, Daniela Markovic, Han Woo, Mehrdad Arjomandi, R Graham Barr, Russell P Bowler, Gerard Criner, Jeffrey L Curtis, Mark T Dransfield, M Bradley Drummond, Spyr...> ;American Journal of Respiratory and Critical Care Medicine. 2024 Mar 20
Design of the STRIVE-IPF trial- study of therapeutic plasma exchange, rituximab, and intravenous immunoglobulin for acute exacerbations of idiopathic pulmonary fibrosis.
Tejaswini Kulkarni, Gerard J Criner, Daniel J Kass, Ivan O Rosas, Mary Beth Scholand, Daniel F Dilling, Ross Summer, Steven R Duncan> ;BMC Pulmonary Medicine. 2024 Mar 20
Pulmonary Vasodilator Therapy Is Associated with Decreased Mortality in Patients with Chronic Lung Disease and Severe Pulmonary Hypertension.
Olivia Schanz, Gerard J Criner, Parth Rali, Shameek Gayen> ;Journal of Cardiovascular Development and Disease. 2024 Mar 8
Design of the STRIVE-IPF Trial- Study of Therapeutic Plasma Exchange, Rituximab, and Intravenous Immunoglobulin for Acute Exacerbations of Idiopathic Pulmonary Fibrosis.
Tejaswini Kulkarni, Gerard J Criner, Daniel J Kass, Ivan O Rosas, Mary Beth Scholand, Daniel F Dilling, Ross Summer, Steven R Duncan> ;Research Square. 2024 Feb 28
Early Diagnosis and Treatment of COPD: The Costs and Benefits of Case-Finding.
Bhatt, S. P., Shawn D Aaron, Maria Montes de Oca, Bartolome Celli, Surya P Bhatt, Jean Bourbeau, Gerard J Criner, Dawn L DeMeo, David M G Halpin, MeiLan K Han, John R ...> ;American Journal of Respiratory and Critical Care Medicine. 2024 Feb 15
Elevated pulmonary vascular resistance is associated with increased lung transplant waitlist mortality among patients with chronic obstructive pulmonary disease and pu...
Zulty, M., Gayen, S., Criner, G.> ;Respiratory Research. 2024 Feb 7
Critical Care Management of Severe Asthma Exacerbations.
Gordon, M., Desai, P., Cardet, J., Shenoy, K., Gayen, S., Dachert, S., Lashari, B., Criner, G.> ;Journal of Clinical Medicine. 2024 Feb 1
Loss of Airway Phylogenetic Diversity Is Associated with Clinical and Pathobiological Markers of Disease Development in COPD.
Opron, K., Begley, L., Erb-Downward, J., Li, G., Alexis, N., Barjaktarevic, I., Barr, R., Bleecker, E., Boucher, R., Bowler, R., Christenson, S., Comellas, A., Criner,...> ;American Journal of Respiratory and Critical Care Medicine. 2024 Jan 23
Risk of Death and Cardiovascular Events Following an Exacerbation of COPD: The EXACOS-CV US Study.
Kimberly Daniels, Stephan Lanes, Arlene Tave, Michael F Pollack, David M Mannino, Gerard Criner, Amanda Neikirk, Kirsty Rhodes, Norbert Feigler, Clementine Nordon> ;International Journal of Chronic Obstructive Pulmonary Disease. 2024 Jan 1
Utility of rehabilitation prior to bronchoscopic lung volume reduction:analysis of the VENT trial.
Judith Maria Brock, Konstantina Kontogianni, Frank C Sciurba, Gerard J Criner, Felix Herth> ;ERJ Open Research. 2024 Jan 1
The Regulation of Fatty Acid Synthase by Exosomal miR-143-5p and miR-342-5p in Idiopathic Pulmonary Fibrosis.
Hassan Hayek, Ohoud Rehbini, Beata Kosmider, Thomas Brandt, Wissam Chatila, Nathaniel Marchetti, Gerard J Criner, Sudhir Bolla, Raj Kishore, Russell P Bowler, Karim Ba...> ;American Journal of Respiratory Cell and Molecular Biology. 2024 Apr 1
Potential systemic effects of acquired CFTR dysfunction in COPD.
Miravitlles, M., Mall, M., Vogelmeier, C., Hederer, B., Schoenberger, M., Altman, P., Criner, G., Rowe, S.> ;Respiratory Medicine. 2024 Jan 1
Any Decrease in Lung Function is Associated With Worse Clinical Outcomes: Post Hoc Analysis of the IMPACT Interventional Trial.
Halpin, D., Kerwin, E., Tombs, L., Lipson, D., Martinez, F., Singh, D., Han, M., Criner, G., Wise, R.> ;Chronic Obstructive Pulmonary Diseases. 2024 Jan 25
Associations Between Coronary Artery Calcium Score and Exacerbation Risk in BLOCK-COPD.
Sharon X Ling, Erika S Helgeson, Helen Voelker, Wassim W Labaki, Daniel Meza, Oisin O'Corragain, Jennifer Y So, Gerard J Criner, MeiLan K Han, Ravi Kalhan, Robert M Re...> ;Chronic Obstructive Pulmonary Diseases. 2024 Jan 25
1 citations
Sustained Clinical Benefits of Spiration Valve System in Patients with Severe Emphysema: 24-Month Follow-Up of EMPROVE.
Gerard J Criner, Jorge M Mallea, Muhanned Abu-Hijleh, Ashutosh Sachdeva, Ravi Kalhan, Christopher A Hergott, Donald R Lazarus, Richard A Mularski, Karel Calero, Michae...> ;Annals of the American Thoracic Society. 2024 Feb 1
Returning incidentally discovered Hepatitis C RNA-seq results to COPDGene study participants.
Bhatt, S. P., Edwin K Silverman, Arthur Y Kim, Barry J Make, Elizabeth A Regan, Jarrett D Morrow, Craig P Hersh, James O'Brien, James D Crapo, Nadia N Hansel, Gerard C...> ;NPJ Genomic Medicine. 2023 Oct 31
2 citations
Clonal Somatic Mutations in Chronic Lung Diseases Are Associated with Reduced Lung Function.
Jeong H Yun, M A Wasay Khan, Auyon Ghosh, Brian D Hobbs, Peter J Castaldi, Craig P Hersh, Peter G Miller, Carlyne D Cool, Frank Sciurba, Lucas Barwick, Andrew H Limper...> ;American Journal of Respiratory and Critical Care Medicine. 2023 Dec 1
Frequency of screening and SBT Technique Trial-North American Weaning Collaboration (FAST-NAWC): an update to the protocol and statistical analysis plan.
Karen E A Burns, Myriam Lafrienier-Roula, Nicholas S Hill, Deborah J Cook, Andrew J E Seely, Bram Rochwerg, Michael Mayette, Frederick D'Aragon, John W Devlin, Peter D...> ;Trials. 2023 Oct 2
Lifestyle Intervention and Excess Weight in Chronic Obstructive Pulmonary Disease (COPD): INSIGHT COPD Randomized Clinical Trial.
David H Au, Emily Gleason, Rachel Hunter-Merrill, Anna E Barón, Margaret Collins, Corina Ronneberg, Nan Lv, Peter Rise, Travis Hee Wai, Robert Plumley, Stephen R Wisni...> ;Annals of the American Thoracic Society. 2023 Dec 1
10 citations
COPD and multimorbidity: recognising and addressing a syndemic occurrence.
Leonardo M Fabbri, Bartolome R Celli, Alvar Agustí, Gerard J Criner, Mark T Dransfield, Miguel Divo, Jamuna K Krishnan, Lies Lahousse, Maria Montes de Oca, Sundeep S S...> ;The Lancet. Respiratory Medicine. 2023 Nov 1
Caveolin-1-derived peptide attenuates cigarette smoke-induced airway and alveolar epithelial injury.
Durgesh Nandini Das, Bijesh Puthusseri, Venkadesaperumal Gopu, Venugopal Krishnan, Ashoka Kumar Bhagavath, Sudhir Bolla, Yogesh Saini, Gerald J Criner, Nathaniel March...> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2023 Nov 1
1 citations
Longitudinal Follow-Up of Participants With Tobacco Exposure and Preserved Spirometry.
William McKleroy, Tracie Shing, Wayne H Anderson, Mehrdad Arjomandi, Hira Anees Awan, Igor Barjaktarevic, R Graham Barr, Eugene R Bleecker, John Boscardin, Russell P B...> ;JAMA. 2023 Aug 1
3 citations
Changes in Lung Volumes with Spirometric Disease Progression in COPD.
Bhatt, S. P., Mehrdad Arjomandi, Siyang Zeng, Jianhong Chen, Surya P Bhatt, Fereidoun Abtin, Igor Barjaktarevic, R Graham Barr, Eugene R Bleecker, Russell G Buhr, Gera...> ;Chronic Obstructive Pulmonary Diseases. 2023 Jul 26
Pulmonary artery diameter correlates with echocardiographic parameters of right ventricular dysfunction in patients with acute pulmonary embolism.
Oisin O'Corragain, Rami Alashram, Gregory Millio, Catherine Vanchiere, John Hojoon Hwang, Maruti Kumaran, Chandra Dass, Huaqing Zhao, Joseph Panero, Vlad Lakhter, Rohi...> ;Lung India. 2023 Jul 7
7 citations
Icenticaftor, a CFTR Potentiator, in COPD: A Multicenter, Parallel-Group, Double-Blind Clinical Trial.
Fernando J Martinez, Gerard J Criner, Christian Gessner, Margret Jandl, Fernando Scherbovsky, Masaharu Shinkai, Thomas M Siler, Claus F Vogelmeier, Robert Voves, Jadwi...> ;American Journal of Respiratory and Critical Care Medicine. 2023 Aug 15
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Journal Articles

Tocilizumab in Patients Hospitalized with Covid-19 Pneumonia
Gerard J Criner, Lavannya Pandit, The New England Journal of Medicine
Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients with Moderate COVID-19
Robert L Gottlieb, Gerard J Criner, Onyema Ogbuagu, Kathleen M Mullane, Anuj Gaggar, Diana M Brainard, Gregory Huhn, JAMA
Association of Dysanapsis with Chronic Obstructive Pulmonary Disease Among Older Adults
Alain Bertoni, Gerard Criner, Mark T Dransfield, Meilan K Han, Nadia N Hansel, Erin D Michos, Elizabeth C Oelsner, Karol E Watson, JAMA
A Gene Expression Classifier from Whole Blood Distinguishes Benign from Malignant Lung Nodules Detected by Low-Dose CT
Anil Vachani, William N Rom, Gerard Criner, Harvey Pass, Clinical Cancer Research
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Authored Content

Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients with Moderate COVID-19August 2020
Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients with Moderate COVID-19August 2020
Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients with Moderate COVID-19August 2020
Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients with Moderate COVID-19August 2020
Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients with Moderate COVID-19August 2020
Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients with Moderate COVID-19August 2020
Failure of Low-Dose Theophylline to Prevent Exacerbations in Patients with COPDOctober 2018
Mepolizumab for Eosinophilic Chronic Obstructive Pulmonary DiseaseSeptember 2017
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Press Mentions

Endobronchial Valves: Sustained Improvement in EmphysemaMay 25th, 2023
Help COPD Patients with More Probing CareSeptember 12th, 2022
PRE-PROOF Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation PRE-PROOFJune 29th, 2022
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